NEJM, Vol 358, pp 369-374, 2008
Chimerism and tolerance in a recipient of a deceased-donor liver transplant
Alexander SI, et al

Complete hematopoietic chimerism and tolerance of a liver allograft from a deceased male donor developed in a 9-year-old girl, with no evidence of graft-versus-host disease 17 months after transplantation. The tolerance was preceded by a period of severe hemolysis, reflecting partial chimerism that was refractory to standard therapies. The hemolysis resolved after the gradual withdrawal of all immunosuppressive therapy.

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Posted: Jan 28, 2008