Current RFPs

Clinical Trials in Immune Tolerance

The ITN  is currently seeking Concept Proposals for novel clinical trials designed to induce immune tolerance in Type 1 Diabetes, transplantation, autoimmune diseases, and allergy and asthma. In addition, the ITN accepts applications for the development of novel tolerance assays or mechanistic studies for the purposes of establishing new surrogate biomarkers of immune tolerance and investigating the mechanisms of clinical tolerance.

Proposals should be submitted via our website: www.immunetolerance.org/submit-a-proposal

Detailed information and instructions: RFP - Clinical Trials in Immune Tolerance

Past RFPs

Request for Proposals - Combination Therapy Tolerance Trials in Allergy and Asthma

The ITN is currently seeking Concept Proposals for novel combination therapy clinical trials designed to induce immune tolerance in allergy and asthma. The ITN is especially interested in the following:

1) Studies with a tolerance endpoint that combine allergen-specific approaches with other immunomodulatory agents.

2) Development of novel tolerance assays to investigate allergen-specific mechanisms of clinical tolerance.

Deadline: August 17, 2012

Detailed information and instructions: RFP - Combination Therapy Trials and Allergy and Asthma

Request for Proposals – Clinical Trials of Allogeneic Solid Organ Transplantation Plus Therapeutic Cell Transfer

The ITN is currently seeking Concept Proposals for novel clinical trials designed to induce immune tolerance in combined allogeneic solid organ transplantation plus therapeutic cell transfer. The specific criteria and instructions for preparing proposals are in the following RFP.

Deadline: August 31, 2011

Detailed Information and Instructions: RFP – Allogeneic Solid Organ Transplantation Plus Therapeutic Cell Transfer

Request for Proposals - Clinical Trials in Rheumatologic Disease

The ITN is currently seeking Concept Proposals for novel clinical trials designed to induce immune tolerance in Rheumatologic Disorders and other areas of Autoimmune Disease.

Deadline: March 1, 2011

Detailed Information and Instructions: RFP - Clinical Trials in Rheumatologic Diseases

Request for Proposals - Clinical Trials in Psoriasis and Autoimmune Dermatological Disorders

The ITN is seeking ‘Proposal Outlines' for novel clinical trials designed to induce immune tolerance in psoriasis and other autoimmune skin disorders, including those mediated by autoantibodies such as pemphigus and pemphigoid.

DEADLINE: August 30, 2009

Detailed information and instructions: RFP - Psoriasis and Autoimmune Dermatological Disorders

Request for Expressions of Interest for Innovative Clinical Trials in Type 1 Diabetes

The purpose of this EOI is to gather information from the scientific community about novel ideas for tolerogenic immunotherapeutic trials in type 1 diabetes (T1D).

DEADLINE: April 13, 2009

Detailed information and instructions: EOI - Type 1 Diabetes