Current RFPs

Clinical Trials in Immune Tolerance

The ITN  is currently seeking Concept Proposals for novel clinical trials designed to induce immune tolerance in allergy and asthma, autoimmune disease, transplantation, and type 1 diabetes. In addition, the ITN accepts applications for the development of novel tolerance assays or mechanistic studies for the purposes of establishing new surrogate biomarkers of immune tolerance and investigating the mechanisms of clinical tolerance.

Proposals should be submitted via our website:

Detailed information and instructions: RFP - Clinical Trials in Immune Tolerance

Request for Proposals – Antigen-Specific T Cell Tolerance Assays for Myelin-Associated Antigens in Multiple Sclerosis

The ITN has an interest in antigen-specific T cell tolerance in multiple sclerosis, an autoimmune disease in which autoreactive T cells specific for myelin-associated antigens are thought to play a role in pathogenesis. Assessment of antigen-specific tolerance in multiple sclerosis will require reliable assays to detect and phenotype T cell responses to myelin-associated antigens in a clinical trial setting. To this end, the ITN is seeking assays for assessing functional tolerance and biomarkers of tolerance in antigen-specific CD4 and CD8 effector and regulatory T cells.  

Deadline: February 13, 2015

Detailed information and instructions: RFP - T Cell Tolerance Assay for Myelin Associated Antigens

More Information: 

Research applications to the ITN are not limited to the RFPs seen here.The ITN accepts "Concept Proposals" year-round through it's always-open call for proposals. Visit the Proposals page for more information.