Publications

Articles

Estimating the ratio of CD4+ to CD8+ T cells using high-throughput sequence data..

J Immunol Methods. 391: 14-21, 2013.

Emerson R, Sherwood A, Desmarais C, Malhotra S, Phippard D, Robins H

[PubMed] [Reprint] [Citation View]
Emerson R, Sherwood A, Desmarais C, Malhotra S, Phippard D, Robins H. Estimating the ratio of CD4+ to CD8+ T cells using high-throughput sequence data.. J Immunol Methods. 391: 14-21, 2013..

HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression.

New Eng L Med. 368: 1850-1852, 2013

Kawai T, Sachs DH, Sykes M, Cosimi BA for the Immune Tolerance Network

[Reprint] [Citation View]
Kawai T, Sachs DH, Sykes M, Cosimi BA for the Immune Tolerance Network. HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression. New Eng L Med. 368: 1850-1852, 2013.

Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: Immunologic effects and efficacy in NOD mice.

PLoS ONE, e54712 2013

Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Schneider D, Calvo TR, Coulombe M, Herold K, Atkinson M, Nepom G, Ehlers M, Staeva T, Garren H, Steinman L, Chan AC, von Herrath M, Pagni PP, Gill RG

[PubMed] [Reprint] [Citation View]
Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Schneider D, Calvo TR, Coulombe M, Herold K, Atkinson M, Nepom G, Ehlers M, Staeva T, Garren H, Steinman L, Chan AC, von Herrath M, Pagni PP, Gill RG. Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: Immunologic effects and efficacy in NOD mice. PLoS ONE, e54712 2013.

Circulating angiopoietin-2 as a biomarker in ANCA-associated Vasculitis.

PLoS ONE. 7:e30197, 2012

Monach PA, Kumpers P, Lukasz A, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Carette S, Ding L, Hoffman GS, Ikle D, Kallenberg CG, Khalidi NA, Langford CA, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Haubitz M, Merkel PA

[PubMed] [Reprint] [Citation View]
Monach PA, Kumpers P, Lukasz A, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Carette S, Ding L, Hoffman GS, Ikle D, Kallenberg CG, Khalidi NA, Langford CA, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Haubitz M, Merkel PA. Circulating angiopoietin-2 as a biomarker in ANCA-associated Vasculitis. PLoS ONE. 7:e30197, 2012.

Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants.

JAMA. 307: 283-293, 2012

Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP, Rosenthal P, Alonso EM, Philogene MC, Ikle D, Poole KM, Bridges ND, Turka LA, Tchao NK

[PubMed] [Reprint] [Citation View]
Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP, Rosenthal P, Alonso EM, Philogene MC, Ikle D, Poole KM, Bridges ND, Turka LA, Tchao NK. Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants. JAMA. 307: 283-293, 2012.

Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy.

Allergy 67: 217-226

Shamji MH, Francis JN, Calderon MA, Larché M, Kimber I, Lund K, Wurtzen PA, Durham SR, Ljorring C, Frew AJ, Ipsen H

[PubMed] [Reprint] [Citation View]
Shamji MH, Francis JN, Calderon MA, Larché M, Kimber I, Lund K, Wurtzen PA, Durham SR, Ljorring C, Frew AJ, Ipsen H. Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy. Allergy 67: 217-226.

Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study.

J Allergy Clin Immunol. 12: S0091-6749, 2012

Du Toit G, Roberts G, Sayre PH, Plaut M, Bahnson HT, Mitchell H, Radulovic S, Chan S, Fox A, Turcanu V, Lack G

[PubMed] [Reprint] [Citation View]
Du Toit G, Roberts G, Sayre PH, Plaut M, Bahnson HT, Mitchell H, Radulovic S, Chan S, Fox A, Turcanu V, Lack G. Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study. J Allergy Clin Immunol. 12: S0091-6749, 2012.

Lymphodepletion and homeostatic proliferation: Implications for transplantation.

Am J Transplant. 12: 1079-1090, 2012

Tchao NK, Turka LA

[PubMed] [Reprint] [Citation View]
Tchao NK, Turka LA. Lymphodepletion and homeostatic proliferation: Implications for transplantation. Am J Transplant. 12: 1079-1090, 2012.

Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes.

J Immunol Methods. 384: 25-32, 2012

Scadding GW, Calderon MA, Bellido V, Koed GK, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA, Nielsen NC

[PubMed] [Reprint] [Citation View]
Scadding GW, Calderon MA, Bellido V, Koed GK, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA, Nielsen NC. Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes. J Immunol Methods. 384: 25-32, 2012.

QUAliFiER: An automated pipeline for quality assessment of gated flow cytometry data.

BMC Informatics 13: 252, 2012

Finak G, Jiang W, Pardo J, Asare A, Gottardo R

[PubMed] [Citation View]
Finak G, Jiang W, Pardo J, Asare A, Gottardo R. QUAliFiER: An automated pipeline for quality assessment of gated flow cytometry data. BMC Informatics 13: 252, 2012.

Randomized controlled trial of atorvastatin in clinically isolated syndrome.

Neurology. 78: 1171-1178, 2012

Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Ikle D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C, Zamvil SS, ITN020AI Study Management Team, ITN STAyCIS Study Group

[PubMed] [Reprint] [Citation View]
Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Ikle D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C, Zamvil SS, ITN020AI Study Management Team, ITN STAyCIS Study Group. Randomized controlled trial of atorvastatin in clinically isolated syndrome. Neurology. 78: 1171-1178, 2012.

Rapamycin/IL-2 combination therapy in patients with Type 1 Diabetes augments Tregs yet transiently impairs beta-cell function.

Diabetes. 61: 2340-2348, 2012

Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network

[PubMed] [Reprint] [Citation View]
Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network. Rapamycin/IL-2 combination therapy in patients with Type 1 Diabetes augments Tregs yet transiently impairs beta-cell function. Diabetes. 61: 2340-2348, 2012.

Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis..

Ann Rheum Dis. doi: 10.1136/annrheumdis-2012-201981 2012

Monach PA, Warner RL, Tomasson G, Specks U, Stone JH, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Krischer J, Langford CA, Mueller M, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Johnson KJ, Merkel PA

[PubMed] [Reprint] [Citation View]
Monach PA, Warner RL, Tomasson G, Specks U, Stone JH, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Krischer J, Langford CA, Mueller M, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Johnson KJ, Merkel PA. Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis.. Ann Rheum Dis. doi: 10.1136/annrheumdis-2012-201981 2012.

Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts.

Am J Transplant. 11: 1464-1477, 2011

Farris AB, Taheri D, Kawai T, Fazlollahi L, Wong W, Tolkoff-Rubin N, Spitzer TR, Iafrate AJ, Preffer FI, LoCascio SA, Sprangers B, Saidman S, Smith RN, Cosimi AB, Sykes M, Sachs DH, Colvin RB

[PubMed] [Reprint] [Citation View]
Farris AB, Taheri D, Kawai T, Fazlollahi L, Wong W, Tolkoff-Rubin N, Spitzer TR, Iafrate AJ, Preffer FI, LoCascio SA, Sprangers B, Saidman S, Smith RN, Cosimi AB, Sykes M, Sachs DH, Colvin RB. Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts. Am J Transplant. 11: 1464-1477, 2011.

Challenges in the pursuit of immune tolerance.

Immunol Rev. 241:49-62, 2011

Nepom GT, St. Clair EW, Turka LA

[PubMed] [Reprint] [Citation View]
Nepom GT, St. Clair EW, Turka LA. Challenges in the pursuit of immune tolerance. Immunol Rev. 241:49-62, 2011.

Circulating markers of vascular injury and angiogenesis in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Arthritis Rheum 63: 3988-3997, 2011

Monach PA, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Langford CA, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Snyder RD, Merkel PA, Muelle M, Gu YZ

[PubMed] [Reprint] [Citation View]
Monach PA, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Langford CA, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Snyder RD, Merkel PA, Muelle M, Gu YZ. Circulating markers of vascular injury and angiogenesis in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheum 63: 3988-3997, 2011.

Design of the Rituximab in ANCA-associated Vasculitis (RAVE) Trial.

The Open Arthritis Journal: 4, 1-18, 2011

Specks U, Merkel PA, Hoffman GS, Langford CA, Spiera R, Seo P, Kallenberg CGM, St. Clair EW, Ding L, Webber L, Mokhtarani M, Tchao NK, Sayre PH, Seyfert-Margolis V, Ikle D, Brunetta P, Mueller M, Zhang D, Sejismundo L, Stone JH.

[Reprint] [Citation View]
Specks U, Merkel PA, Hoffman GS, Langford CA, Spiera R, Seo P, Kallenberg CGM, St. Clair EW, Ding L, Webber L, Mokhtarani M, Tchao NK, Sayre PH, Seyfert-Margolis V, Ikle D, Brunetta P, Mueller M, Zhang D, Sejismundo L, Stone JH.. Design of the Rituximab in ANCA-associated Vasculitis (RAVE) Trial. The Open Arthritis Journal: 4, 1-18, 2011.

Donor-specific indirect pathway analysis reveals a B-cell independent signature which reflects outcomes in kidney transplant recipients.

Am J Transplant 12: 640-648, 2011

Haynes LD, Jankowska-Gan E, Sheka A, Keller MR, Hernandez-Fuentes MP, Lechler RI, Seyfert-Margolis V, Turka LA, Newell KA, Burlingham WJ

[PubMed] [Reprint] [Citation View]
Haynes LD, Jankowska-Gan E, Sheka A, Keller MR, Hernandez-Fuentes MP, Lechler RI, Seyfert-Margolis V, Turka LA, Newell KA, Burlingham WJ. Donor-specific indirect pathway analysis reveals a B-cell independent signature which reflects outcomes in kidney transplant recipients. Am J Transplant 12: 640-648, 2011.

Increased frequencies of myelin oligodendrocyte glycoprotein/MHC Class II-binding CD4 cells in patients with multiple sclerosis.

J Immunol 187: 1039-1046, 2011

Kent SC, Yang J, Bourcier K, Bradshaw EM, Seyfert-Margolis V, Nepom GT, Kwok WW, Hafler DA, Radassi K

[PubMed] [Reprint] [Citation View]
Kent SC, Yang J, Bourcier K, Bradshaw EM, Seyfert-Margolis V, Nepom GT, Kwok WW, Hafler DA, Radassi K. Increased frequencies of myelin oligodendrocyte glycoprotein/MHC Class II-binding CD4 cells in patients with multiple sclerosis. J Immunol 187: 1039-1046, 2011.

Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies.

J Allergy Clin Immunol 127: 509-516, 2011

James LK, Shamji MH, Walker SM, Wilson DR, Wachholz PA, Francis JN, Jacobson MR, Kimber I, Till SJ, Durham, SR

[PubMed] [Reprint] [Citation View]
James LK, Shamji MH, Walker SM, Wilson DR, Wachholz PA, Francis JN, Jacobson MR, Kimber I, Till SJ, Durham, SR. Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies. J Allergy Clin Immunol 127: 509-516, 2011.

Regulatory cells and cell signatures in clinical transplantation tolerance.

Curr Opin Immunol. 23: 655-659, 2011

Newell KA, Phippard D, Turka LA

[PubMed] [Reprint] [Citation View]
Newell KA, Phippard D, Turka LA. Regulatory cells and cell signatures in clinical transplantation tolerance. Curr Opin Immunol. 23: 655-659, 2011.

Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy.

J Autoimmun. 34: 408-415, 2010

Orban T, Farkas K, Jalahej H, Kis J, Treszl A, Falk B, Reijonen H, Wolfsdorf J, Ricker A, Matthews JB, Tchao N, Sayre P, Bianchine P

[PubMed] [Reprint] [Citation View]
Orban T, Farkas K, Jalahej H, Kis J, Treszl A, Falk B, Reijonen H, Wolfsdorf J, Ricker A, Matthews JB, Tchao N, Sayre P, Bianchine P. Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy. J Autoimmun. 34: 408-415, 2010.

Bringing transplantation tolerance into the clinic: lessons from the ITN and RISET for the Establishment of Tolerance consortia.

Curr Opin Organ Transplant 15: 441-448, 2010

Turka LA, Wood K, Bluestone JA

[PubMed] [Citation View]
Turka LA, Wood K, Bluestone JA. Bringing transplantation tolerance into the clinic: lessons from the ITN and RISET for the Establishment of Tolerance consortia. Curr Opin Organ Transplant 15: 441-448, 2010.

Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN–JDRF Type 1 Diabetes Combination Therapy Assessment Group.

Clin. Exp. Immunol. 160: 176-184, 2010

Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, ITN/JDRF Type 1 Diabetes Combination Therapy Assessment Group

[Reprint] [Citation View]
Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, ITN/JDRF Type 1 Diabetes Combination Therapy Assessment Group. Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN–JDRF Type 1 Diabetes Combination Therapy Assessment Group. Clin. Exp. Immunol. 160: 176-184, 2010.

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans.

J Clin Invest 120: 1848-1861, 2010

Bourcier K, Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, Chapman S, Craciun L, Sergeant R, Brouard S, Rovis F, Jimenez E, Ballow A, Giral M, Rebollo-Mesa I, Le Moine A, Braudeau C, Hilton R, Gerstmayer B, Sharif A, Krajewska M, Lord GM

[PubMed] [Reprint] [Citation View]
Bourcier K, Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, Chapman S, Craciun L, Sergeant R, Brouard S, Rovis F, Jimenez E, Ballow A, Giral M, Rebollo-Mesa I, Le Moine A, Braudeau C, Hilton R, Gerstmayer B, Sharif A, Krajewska M, Lord GM. Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest 120: 1848-1861, 2010.

Identification of a B cell signature associated with renal transplant tolerance in humans.

J Clin Invest 120: 1836-1847, 2010

Newell KA, Asare A, Bourcier K, Burlingham WJ, Turka LA, Kirk AD, Gisler TD, Suthanthiran M, Marks WH, Sanz I, Lechler RI, Hernandez-Fuentes MP, Seyfert-Margolis VL

[PubMed] [Reprint] [Citation View]
Newell KA, Asare A, Bourcier K, Burlingham WJ, Turka LA, Kirk AD, Gisler TD, Suthanthiran M, Marks WH, Sanz I, Lechler RI, Hernandez-Fuentes MP, Seyfert-Margolis VL. Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest 120: 1836-1847, 2010.

Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance.

Transplantation. 90: 1607-1615, 2010.

LoCascio SA, Morokata T, Chittenden M, Preffer FI, Dombkowski DM, Andreola G, Crisalli K, Kawai T, Saidman Sl, Spitzer TR, Tolkoff-Rubin N, Cosimi BA, Sachs DH, Sykes M

[PubMed] [Citation View]
LoCascio SA, Morokata T, Chittenden M, Preffer FI, Dombkowski DM, Andreola G, Crisalli K, Kawai T, Saidman Sl, Spitzer TR, Tolkoff-Rubin N, Cosimi BA, Sachs DH, Sykes M. Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance. Transplantation. 90: 1607-1615, 2010..

Per-channel basis normalization methods for flow cytometry data.

Cytometry A 77:121-31, 2010

Seyfert-Margolis V, Bourcier K, Asare A, Hahne F, Khodabakhshi AH, Bashashati A, Wong CJ, Gascoyne RD, Weng AP, Lumley T, Gentleman R, Brinkman RR

[PubMed] [Reprint] [Citation View]
Seyfert-Margolis V, Bourcier K, Asare A, Hahne F, Khodabakhshi AH, Bashashati A, Wong CJ, Gascoyne RD, Weng AP, Lumley T, Gentleman R, Brinkman RR. Per-channel basis normalization methods for flow cytometry data. Cytometry A 77:121-31, 2010.

Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis.

New Eng J Med 363: 221-232, 2010

Stone JH, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, St. Clair EW, Turkiewicz A, Tchao NK, Webber L, Ding L, Sejismundo LP, Mieras K, Weitzenkamp D, Ikle D, Seyfert-Margolis V, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh KA, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Specks U, RAVE-ITN Research Group

[PubMed] [Reprint] [Citation View]
Stone JH, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, St. Clair EW, Turkiewicz A, Tchao NK, Webber L, Ding L, Sejismundo LP, Mieras K, Weitzenkamp D, Ikle D, Seyfert-Margolis V, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh KA, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Specks U, RAVE-ITN Research Group. Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis. New Eng J Med 363: 221-232, 2010.

Ten years of the Immune Tolerance Network: An integrated clinical research organization.

Sci Transl Med 2, 19cm7, 2010

Bluestone JA, Krensky AM, Turka LA, Rotrosen D, Matthews JB

[PubMed] [Reprint] [Citation View]
Bluestone JA, Krensky AM, Turka LA, Rotrosen D, Matthews JB. Ten years of the Immune Tolerance Network: An integrated clinical research organization. Sci Transl Med 2, 19cm7, 2010.

The Immune Tolerance Network at 10 years: Tolerance research at the bedside.

Nature Reviews Immunology 10: 797-803, 2010

Bluestone JA, Auchincloss H, Nepom GT, Rotrosen D, St. Clair EW, Turka LA

[PubMed] [Reprint] [Citation View]
Bluestone JA, Auchincloss H, Nepom GT, Rotrosen D, St. Clair EW, Turka LA. The Immune Tolerance Network at 10 years: Tolerance research at the bedside. Nature Reviews Immunology 10: 797-803, 2010.

B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans.

Am J Transplant 9: 2126-35, 2009

Wong W, Saidman Sl, Chittenden M, Shaffer J, Tolkoff-Rubin N, Spitzer TR, Colvin RB, Cosimi AB, Kawai T, Sachs DH, Sykes M, Porcheray F, De Vito J, Girouard TC, Dey BR, Zorn E

[PubMed] [Reprint] [Citation View]
Wong W, Saidman Sl, Chittenden M, Shaffer J, Tolkoff-Rubin N, Spitzer TR, Colvin RB, Cosimi AB, Kawai T, Sachs DH, Sykes M, Porcheray F, De Vito J, Girouard TC, Dey BR, Zorn E. B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans. Am J Transplant 9: 2126-35, 2009.

Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring.

American Journal of Transplantation 9: 1087-1098, 2009.

Knechtle SJ, Pascual J, Bloom DD, Torrealba JR, Jankowska-Gan E, Burlingham WJ, Kwun J, Colvin RB, Bourcier K, Sollinger HW, Seyferg-Margolis V

[PubMed] [Reprint] [Citation View]
Knechtle SJ, Pascual J, Bloom DD, Torrealba JR, Jankowska-Gan E, Burlingham WJ, Kwun J, Colvin RB, Bourcier K, Sollinger HW, Seyferg-Margolis V. Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring. American Journal of Transplantation 9: 1087-1098, 2009..

Murine high specificity/sensitivity competitive europium insulin autoantibody assay.

Diabetes Technol Ther 11:227-33, 2009

Miao D, Yu L, Eisenbarth GS, Babaya N, Liu E, Li M

[PubMed] [Reprint] [Citation View]
Miao D, Yu L, Eisenbarth GS, Babaya N, Liu E, Li M. Murine high specificity/sensitivity competitive europium insulin autoantibody assay. Diabetes Technol Ther 11:227-33, 2009.

Power enhancement via multivariate outlier testing with gene expression arrays.

Bioinformatics 25: 48-53, 2009

Asare A, Gao Z, Carey VJ, Wang R, Seyfert-Margolis V

[PubMed] [Reprint] [Citation View]
Asare A, Gao Z, Carey VJ, Wang R, Seyfert-Margolis V. Power enhancement via multivariate outlier testing with gene expression arrays. Bioinformatics 25: 48-53, 2009.

Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays.

BMC Immunol 10:52, 2009

de Jager W, Bourcier K, Rijkers GT, Prakken BJ, Seyfert-Margolis V

[PubMed] [Reprint] [Citation View]
de Jager W, Bourcier K, Rijkers GT, Prakken BJ, Seyfert-Margolis V. Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays. BMC Immunol 10:52, 2009.

Representing and Reasoning with Temporal Constraints in Clinical Trials Using Semantic Technologies.

Biomedical Engineering Systems and Technologies, Springer Berlin Heidelberg, Fred A, Filipe J, Gamboa H, Editors, pp 520-530, 2009

Shankar RD, Martins SB, O'Connor MJ, Parrish DB, Das AK

[Reprint] [Citation View]
Shankar RD, Martins SB, O'Connor MJ, Parrish DB, Das AK. Representing and Reasoning with Temporal Constraints in Clinical Trials Using Semantic Technologies. Biomedical Engineering Systems and Technologies, Springer Berlin Heidelberg, Fred A, Filipe J, Gamboa H, Editors, pp 520-530, 2009.

Single nucleotide transcription factor 7-like 2 (TCF7L2) gene polymorphisms in antiislet autoantibody-negative patients at onset of diabetes.

J Clin Endocrinol Metab 94:504-10, 2009

Yu L, Miao D, Eisenbarth GS, Yu J, Steck AK, Babu S, McFann K, Hutton J, Klingensmith G

[PubMed] [Reprint] [Citation View]
Yu L, Miao D, Eisenbarth GS, Yu J, Steck AK, Babu S, McFann K, Hutton J, Klingensmith G. Single nucleotide transcription factor 7-like 2 (TCF7L2) gene polymorphisms in antiislet autoantibody-negative patients at onset of diabetes. J Clin Endocrinol Metab 94:504-10, 2009.

Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years.

Clin Immunol 132: 166-173, 2009

Herold KC, Gitelman S, Greenbaum C, Puck J, Hagopian W, Gottlieb P, Sayre P, Bianchine P, Wong E, Seyfert-Margolis V, Bourcier K, Bluestone JA, ImmuneTolerance Network ITN007AI Study Group

[PubMed] [Reprint] [Citation View]
Herold KC, Gitelman S, Greenbaum C, Puck J, Hagopian W, Gottlieb P, Sayre P, Bianchine P, Wong E, Seyfert-Margolis V, Bourcier K, Bluestone JA, ImmuneTolerance Network ITN007AI Study Group. Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years. Clin Immunol 132: 166-173, 2009.

Validated protocol for FoxP3 reveals increased expression in type 1 diabetes patients.

Cytometry B Clin Cytom 76B: 69-78, 2009

Grant J, Bourcier K, Wallace S, Pan D, Conway A, Seyfert-Margolis V, Wallace PK

[PubMed] [Reprint] [Citation View]
Grant J, Bourcier K, Wallace S, Pan D, Conway A, Seyfert-Margolis V, Wallace PK. Validated protocol for FoxP3 reveals increased expression in type 1 diabetes patients. Cytometry B Clin Cytom 76B: 69-78, 2009.

CTLA4Ig treatment in patients with multiple sclerosis: An open-label, phase 1 clinical trial.

Neurology 71: 917-924, 2008

Viglietta V, Bourcier K, Buckle GJ, Healy B, Weiner HL, Hafler DA, Egorova S, Rusche JR, Khoury SJ, Guttman CR

[PubMed] [Reprint] [Citation View]
Viglietta V, Bourcier K, Buckle GJ, Healy B, Weiner HL, Hafler DA, Egorova S, Rusche JR, Khoury SJ, Guttman CR. CTLA4Ig treatment in patients with multiple sclerosis: An open-label, phase 1 clinical trial. Neurology 71: 917-924, 2008.

Differential gene expression profiles are dependent upon method of peripheral blood collection and RNA isolation.

BMC Genomics 9:474, 2008

Asare AL, Kolchinsky SA, Gao Z, Wang R, Raddassi K, Bourcier K, Seyfert-Margolis V

[PubMed] [Reprint] [Citation View]
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Grass pollen immunotherapy: IL-10 induction and suppression of late responses precedes IgG4 inhibitory antibody activity.

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Francis JN, James LK, Paraskevopoulos G, Wong C, Calderon MA, Durham SR, Till SJ

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HLA-Mismatched renal transplantation without maintenance immunosuppression.

N Engl J Med 358: 353-61, 2008.

Kawai T, Cosimi AB, Spitzer TR, Tolkoff-Rubin N, Suthanthiran M, Saidman Sl, Shaffer J, Preffer FI, Ding R, Sharma V, Fishman JA, Dey B, Hertl M, Goes NB, Wong W, Colvin RB, Sykes M, Sachs DH, Ko DS, Williams WW Jr.

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Knowledge-data integration for temporal reasoning in a clinical trial system.

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O'Connor MJ, Shankar RD, Parrish DB, Das AK

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Marking a path to transplant tolerance [Commentary].

J Clin Invest 118:2684-6, 2008

Seyfert-Margolis V, Turka LA

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MIFlowCyt: the minimum information about a Flow Cytometry Experiment.

Cytometry A 73:926-30, 2008

Lee JA, Spidlen J, Boyce K, Cai J, Crosbie N, Dalphin M, Furlong J, Gasparetto M, Goldberg M, Goralczyk EM, Hyun B, Jansen K, Kollmann T, Kong M, Leif R, McWeeney S, Moloshok TD, Moore W, Nolan G, Nolan J, Nikolich-Zugich J, Parrish D, Purcell B, Qian Y, Selvaraj B, Smith C, Tchuvatkina O, Wertheimer A, Wilkinson P, Wilson C, Wood J, Scheuermann RH, Brinkman RR, Zigon R, International Society for Advancement of Cytometry Data Standards Tawsk Force

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Retrospective tissue typing of the kidney donor from recipient urine.

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Srikantha M, Sergeant R, Khan T, Lechler RI, Davey N, Hernandez-Fuentes MP, Warrens AN

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Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis.

Immunology 123: 66-78, 2008.

Vandenbark AA, Culbertson NE, Bartholomew RM, Huan J, Agotsch M, LaTocha D, Yadav V, Mass M, Whitham R, Lovera J, Milano J, Theofan G, Chou YK, Offner H, Bourdette DN

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A robust immunoassay for anti-interferon autoantibodies that is highly specific for patients with autoimmune polyglandular syndrome type 1.

Clin Immunol 125:131-137, 2007

Zhang L, Barker JM, Babu S, Su M, Stenerson M, Eisenbarth GS, Cheng M, Shum A, Zamir E, Badolato R, Law A, Anderson MS

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