Publications

Articles

Development of cockroach immunotherapy by the Inner-City Asthma Consortium.

J Allergy Clin Immunol 2014; 133(3)846-852. PMID: 24184147, PMCID: 3943647.

Togias A, Durham SR, Shamji MH, Wood RA, Wildfire J, Visness CM, Matsui EC, Gruchalla R, Hershey G, Liu AH, O’Connor GT, Pongracic JA, Zoratti E, Little F, Granada M, Kennedy S, Busse WW.

[PubMed] [Citation View]
Togias A, Durham SR, Shamji MH, Wood RA, Wildfire J, Visness CM, Matsui EC, Gruchalla R, Hershey G, Liu AH, O’Connor GT, Pongracic JA, Zoratti E, Little F, Granada M, Kennedy S, Busse WW.. Development of cockroach immunotherapy by the Inner-City Asthma Consortium. J Allergy Clin Immunol 2014; 133(3)846-852. PMID: 24184147, PMCID: 3943647..

High-throughput flow cytometry data normalization for clinical trials.

Cytometry A 2014; 85(3):277-286. PMID: 24382714, PMCID: PMC3992339.

Finak G, Jiang W, Sanz I, Phippard D, Gottardo R, Krouse K, Wei C, Asare D, De Rosa SC, Self S

[PubMed] [Reprint] [Citation View]
Finak G, Jiang W, Sanz I, Phippard D, Gottardo R, Krouse K, Wei C, Asare D, De Rosa SC, Self S. High-throughput flow cytometry data normalization for clinical trials. Cytometry A 2014; 85(3):277-286. PMID: 24382714, PMCID: PMC3992339..

Long-Term Results in Recipients of Combined HLA-Mismatched Kidney and Bone Marrow Transplantation Without Maintenance Immunosuppression.

Am J Transplant 2014 Jul; 14(7):1599-611. PMID: 24903438

Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman Sl, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Wong W, Morris H, LoCascio SA, Sayre P, Williams WW, Colvin RB, Sykes M, Gao B, Shonts B, Smith R-N, Cosimi AB.

[PubMed] [Reprint] [Citation View]
Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman Sl, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Wong W, Morris H, LoCascio SA, Sayre P, Williams WW, Colvin RB, Sykes M, Gao B, Shonts B, Smith R-N, Cosimi AB.. Long-Term Results in Recipients of Combined HLA-Mismatched Kidney and Bone Marrow Transplantation Without Maintenance Immunosuppression. Am J Transplant 2014 Jul; 14(7):1599-611. PMID: 24903438.

Magnitude and mechanisms of glucose counterregulation following islet transplantation in patients with type 1 diabetes suffering from severe hypoglycaemic episodes.

Diabetologia 2014; 57(3):623-632.

Brendel MD, Bretzel RG, Ang M, Meyer C, Linn T

[Citation View]
Brendel MD, Bretzel RG, Ang M, Meyer C, Linn T. Magnitude and mechanisms of glucose counterregulation following islet transplantation in patients with type 1 diabetes suffering from severe hypoglycaemic episodes. Diabetologia 2014; 57(3):623-632..

Restoring the balance: Immunotherapeutic combinations for autoimmune disease.

Dis Model Mech 2014; 7:503-513. PMID:24795433, PMCID: PMC4007402

Smilek DE, Ehers MR, Nepom GT

[PubMed] [Reprint] [Citation View]
Smilek DE, Ehers MR, Nepom GT. Restoring the balance: Immunotherapeutic combinations for autoimmune disease. Dis Model Mech 2014; 7:503-513. PMID:24795433, PMCID: PMC4007402.

Rituximab for the Treatment of Relapses in ANCA-associated Vasculitis.

Arthritis Rheumatol 2014 Jul 21. [Epub ahead of print]. PMID:25047592

Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Tchao NK, Viviano L, Ding L, Ikle D, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH for the RAVE-ITN Research Group, Villareal M

[PubMed] [Citation View]
Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Tchao NK, Viviano L, Ding L, Ikle D, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH for the RAVE-ITN Research Group, Villareal M. Rituximab for the Treatment of Relapses in ANCA-associated Vasculitis. Arthritis Rheumatol 2014 Jul 21. [Epub ahead of print]. PMID:25047592.

Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy.

J Allergy Clin Immunol 2014;133(2):468-475. PMID: 24361082, PMCID: 3960331.

Shamji MH, Durham SR, Vickery BP, Scurlock AM, Kulis M, Steele PH, Kamilaris J, Berglund JP, Burk C, Hiegel A, Carlisle S, Christie L, Perry TT, Pesek RD, Sheikh S, Virkud Y, Smith PB, Jones SM, Burks AW

[PubMed] [Citation View]
Shamji MH, Durham SR, Vickery BP, Scurlock AM, Kulis M, Steele PH, Kamilaris J, Berglund JP, Burk C, Hiegel A, Carlisle S, Christie L, Perry TT, Pesek RD, Sheikh S, Virkud Y, Smith PB, Jones SM, Burks AW. Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy. J Allergy Clin Immunol 2014;133(2):468-475. PMID: 24361082, PMCID: 3960331..

T cell repertoire following autologous stem cell transplantation for multiple sclerosis.

J Clin Invest 2014; 124(3):1168-1172. PMID: 24531550, PMCID:3934160.

Muraro PA, Robins H, Malhotra S, Howell M, Phippard D, Desmarais C, de Paula Alves Sousa A, Griffith LM, Lim N, Nash RA, Turka LA

[PubMed] [Reprint] [Citation View]
Muraro PA, Robins H, Malhotra S, Howell M, Phippard D, Desmarais C, de Paula Alves Sousa A, Griffith LM, Lim N, Nash RA, Turka LA. T cell repertoire following autologous stem cell transplantation for multiple sclerosis. J Clin Invest 2014; 124(3):1168-1172. PMID: 24531550, PMCID:3934160..

Targeted immune interventions for type 1 diabetes: Not as easy as it looks!.

Curr Opin Diabetes Endorcinol Obes. 2014 Aug;21(4):271-8. PMID: 24983393, PMCID: 4133939.

Rigby MR, Ehlers MR

[PubMed] [Citation View]
Rigby MR, Ehlers MR. Targeted immune interventions for type 1 diabetes: Not as easy as it looks!. Curr Opin Diabetes Endorcinol Obes. 2014 Aug;21(4):271-8. PMID: 24983393, PMCID: 4133939..

Ancillary study management systems: a review of needs.

BMC Med Inform Decis Mak 2014; 13:5. PMID: 23294514, PMCID: 3564696.

Rauch A, Asare S, Asare A, Nelson EK, Piehler B, Ramsay S, Holman D, Igra M

[PubMed] [Reprint] [Citation View]
Rauch A, Asare S, Asare A, Nelson EK, Piehler B, Ramsay S, Holman D, Igra M. Ancillary study management systems: a review of needs. BMC Med Inform Decis Mak 2014; 13:5. PMID: 23294514, PMCID: 3564696..

Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial.

Lancet Diabetes Endocrinol 2013;1(4):306-316. PMID: 24622416.

Gitelman SE, Gottlieb PA, Rigby MR, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, Ding L, Bluestone JA, Ehlers MR, the START Study Team

[Reprint] [Citation View]
Gitelman SE, Gottlieb PA, Rigby MR, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, Ding L, Bluestone JA, Ehlers MR, the START Study Team. Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial. Lancet Diabetes Endocrinol 2013;1(4):306-316. PMID: 24622416..

Clinical Outcomes of Remission Induction Therapy for Severe Antineutrophil Cytoplasmic Antibody–Associated Vasculitis.

Arthritis Rheum 2013 Sep;65(9):2441-9. PMID:23754238.

Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Tchao NK, Viviano L, Ding L, Sejismundo LP, Mieras K, Ikle D, Jepson B, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH, for the Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group

[PubMed] [Reprint] [Citation View]
Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Tchao NK, Viviano L, Ding L, Sejismundo LP, Mieras K, Ikle D, Jepson B, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH, for the Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group. Clinical Outcomes of Remission Induction Therapy for Severe Antineutrophil Cytoplasmic Antibody–Associated Vasculitis. Arthritis Rheum 2013 Sep;65(9):2441-9. PMID:23754238..

Efficacy of Remission-Induction Regimens for ANCA-Associated Vasculitis.

N Engl J Med. 2013 Aug;369(5):417-427. PMID:23902481.

Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Fessler BJ, Ding L, Viviano L, Tchao NK, Phippard DJ, Asare AL, Lim N, Ikle D, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Mueller M, Sejismundo LP, Mieras K, Stone JH for the RAVE-ITN Research Group

[PubMed] [Reprint] [Citation View]
Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Fessler BJ, Ding L, Viviano L, Tchao NK, Phippard DJ, Asare AL, Lim N, Ikle D, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Mueller M, Sejismundo LP, Mieras K, Stone JH for the RAVE-ITN Research Group. Efficacy of Remission-Induction Regimens for ANCA-Associated Vasculitis. N Engl J Med. 2013 Aug;369(5):417-427. PMID:23902481..

Estimating the ratio of CD4+ to CD8+ T cells using high-throughput sequence data..

J Immunol Methods 2013;391(1-2):14-21. PMID: 23428915

Emerson R, Sherwood A, Desmarais C, Malhotra S, Phippard D, Robins H

[PubMed] [Reprint] [Citation View]
Emerson R, Sherwood A, Desmarais C, Malhotra S, Phippard D, Robins H. Estimating the ratio of CD4+ to CD8+ T cells using high-throughput sequence data.. J Immunol Methods 2013;391(1-2):14-21. PMID: 23428915.

HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression.

New Eng L Med 2013; 368(19):1850-1852. PMID: 23656665, PMCID: 3760499.

Kawai T, Sachs DH, Sykes M, Cosimi BA for the Immune Tolerance Network

[PubMed] [Citation View]
Kawai T, Sachs DH, Sykes M, Cosimi BA for the Immune Tolerance Network. HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression. New Eng L Med 2013; 368(19):1850-1852. PMID: 23656665, PMCID: 3760499..

Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience.

Rev Diabet Stud 2012; 9(4):359-371. PMID:23804273, PMCID:3740703.

Ehlers MR, Nepom GT

[PubMed] [Reprint] [Citation View]
Ehlers MR, Nepom GT. Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience. Rev Diabet Stud 2012; 9(4):359-371. PMID:23804273, PMCID:3740703..

Pre-existing epithelial diversity in normal human livers: A tissue-tethered cytometric analysis in portal/periportal epithelial cells.

Hepatology 2013; 57(4):1632-1643. PMID: 23150208, PMCID: 3612393.

Isse K, Demetris AJ, Lesniak A, Grama K, Maier J, Specht S, Castillo-Rama M, Lunz J, Roysam B, Michalopoulos G

[PubMed] [Citation View]
Isse K, Demetris AJ, Lesniak A, Grama K, Maier J, Specht S, Castillo-Rama M, Lunz J, Roysam B, Michalopoulos G. Pre-existing epithelial diversity in normal human livers: A tissue-tethered cytometric analysis in portal/periportal epithelial cells. Hepatology 2013; 57(4):1632-1643. PMID: 23150208, PMCID: 3612393..

Proinsulin/insulin autoantibodies measured with electrochemiluminescent assay are the earliest indicator of prediabetic islet autoimmunity.

Diabetes Care 2013; 36(8):2266-2270. PMID: 23423694, PMCID: 3714529.

Yu L, Miao D, Steck AK, Dong F, Fouts AR, Wenzlau JM

[PubMed] [Reprint] [Citation View]
Yu L, Miao D, Steck AK, Dong F, Fouts AR, Wenzlau JM. Proinsulin/insulin autoantibodies measured with electrochemiluminescent assay are the earliest indicator of prediabetic islet autoimmunity. Diabetes Care 2013; 36(8):2266-2270. PMID: 23423694, PMCID: 3714529..

Prophylactic use of sublingual allergen immunotherapy in high-risk children: A pilot study.

J Allergy Clin Immunology 2013; 132(4):991-993. PMID: 23768574.

Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P

[PubMed] [Reprint] [Citation View]
Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P. Prophylactic use of sublingual allergen immunotherapy in high-risk children: A pilot study. J Allergy Clin Immunology 2013; 132(4):991-993. PMID: 23768574..

Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial.

Lancet Diabetes Endocrinol 2013;1(4):284-294. PMID: 24622414, PMCID: 3957186.

Rigby MR, DiMeglio LA, Rendell MS, Felner E, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, and the T1DAL Study Team

[Reprint] [Citation View]
Rigby MR, DiMeglio LA, Rendell MS, Felner E, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, and the T1DAL Study Team. Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Diabetes Endocrinol 2013;1(4):284-294. PMID: 24622414, PMCID: 3957186..

Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: Metabolic and immunologic features at baseline identify a subgroup of responders.

Diabetes 2013 Nov;62(11):3766-3774. PMID:23835333, PMCID:3806618.

Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA, the AbATE Study Team

[PubMed] [Reprint] [Citation View]
Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA, the AbATE Study Team. Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: Metabolic and immunologic features at baseline identify a subgroup of responders. Diabetes 2013 Nov;62(11):3766-3774. PMID:23835333, PMCID:3806618..

Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: Immunologic effects and efficacy in NOD mice.

PLoS One 2013;8(2):e54712. PMID: 23405091, PMCID: 3566105.

Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, Nepom G, Ehlers M, Staeva T, Garren H, Steinman L, Chan AC, von Herrath M

[PubMed] [Reprint] [Citation View]
Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, Nepom G, Ehlers M, Staeva T, Garren H, Steinman L, Chan AC, von Herrath M. Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: Immunologic effects and efficacy in NOD mice. PLoS One 2013;8(2):e54712. PMID: 23405091, PMCID: 3566105..

Type 1 diabetes: primary antigen/peptide/register/trimolecular complex.

Immunol Res 2013; 55(0):270-276. PMID: 22956469, PMCID: 3936464.

Eisenbarth GS, Sosinowski T

[PubMed] [Reprint] [Citation View]
Eisenbarth GS, Sosinowski T. Type 1 diabetes: primary antigen/peptide/register/trimolecular complex. Immunol Res 2013; 55(0):270-276. PMID: 22956469, PMCID: 3936464..

Circulating angiopoietin-2 as a biomarker in ANCA-associated Vasculitis.

PLoS One 2012;7(1):e30197. PMID: 22279570, PMCID: 3261176.

Monach PA, Kumpers P, Lukasz A, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Carette S, Ding L, Hoffman GS, Ikle D, Kallenberg CG, Khalidi NA, Langford CA, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Haubitz M, Merkel PA

[PubMed] [Reprint] [Citation View]
Monach PA, Kumpers P, Lukasz A, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Carette S, Ding L, Hoffman GS, Ikle D, Kallenberg CG, Khalidi NA, Langford CA, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Haubitz M, Merkel PA. Circulating angiopoietin-2 as a biomarker in ANCA-associated Vasculitis. PLoS One 2012;7(1):e30197. PMID: 22279570, PMCID: 3261176..

Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants.

JAMA 2012 Jan; 307(3):283-293. PMID: 22253395.

Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP, Rosenthal P, Alonso EM, Philogene MC, Ikle D, Poole KM, Bridges ND, Turka LA, Tchao NK

[PubMed] [Reprint] [Citation View]
Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP, Rosenthal P, Alonso EM, Philogene MC, Ikle D, Poole KM, Bridges ND, Turka LA, Tchao NK. Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants. JAMA 2012 Jan; 307(3):283-293. PMID: 22253395..

Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy.

Allergy 2012 Feb; 67(2):217-226. PMID: 22077562.

Shamji MH, Ljorring C, Francis JN, Calderon MA, Larché M, Kimber I, Frew AJ, Ipsen H, Lund K, Wurtzen PA, Durham SR

[PubMed] [Reprint] [Citation View]
Shamji MH, Ljorring C, Francis JN, Calderon MA, Larché M, Kimber I, Frew AJ, Ipsen H, Lund K, Wurtzen PA, Durham SR. Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy. Allergy 2012 Feb; 67(2):217-226. PMID: 22077562..

Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study.

J Allergy Clin Immunol 2013 Jan; 131(1):135-143.e1-12. PMID: 23174658.

Du Toit G, Roberts G, Sayre PH, Plaut M, Bahnson HT, Mitchell H, Radulovic S, Chan S, Fox A, Turcanu V, Lack G

[PubMed] [Reprint] [Citation View]
Du Toit G, Roberts G, Sayre PH, Plaut M, Bahnson HT, Mitchell H, Radulovic S, Chan S, Fox A, Turcanu V, Lack G. Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study. J Allergy Clin Immunol 2013 Jan; 131(1):135-143.e1-12. PMID: 23174658..

Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes.

J Immunol Methods 2012 Oct;384(1-2): 25-32. PMID: 22759401.

Scadding GW, Calderon MA, Bellido V, Koed GK, Nielsen NC, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA

[PubMed] [Reprint] [Citation View]
Scadding GW, Calderon MA, Bellido V, Koed GK, Nielsen NC, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA. Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes. J Immunol Methods 2012 Oct;384(1-2): 25-32. PMID: 22759401..

QUAliFiER: An automated pipeline for quality assessment of gated flow cytometry data.

BMC Informatics 2012 Sep; 13:252. PMID: 23020243, PMCID: 3499158.

Finak G, Jiang W, Pardo J, Asare A, Gottardo R

[PubMed] [Citation View]
Finak G, Jiang W, Pardo J, Asare A, Gottardo R. QUAliFiER: An automated pipeline for quality assessment of gated flow cytometry data. BMC Informatics 2012 Sep; 13:252. PMID: 23020243, PMCID: 3499158..

Randomized controlled trial of atorvastatin in clinically isolated syndrome.

Neurology. 2012 Apr;78(15):1171-8. PMID: 22459680, PMCID: 3320055.

Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Ikle D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C, Zamvil SS, ITN020AI Study Management Team, ITN STAyCIS Study Group

[PubMed] [Reprint] [Citation View]
Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Ikle D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C, Zamvil SS, ITN020AI Study Management Team, ITN STAyCIS Study Group. Randomized controlled trial of atorvastatin in clinically isolated syndrome. Neurology. 2012 Apr;78(15):1171-8. PMID: 22459680, PMCID: 3320055..

Rapamycin/IL-2 combination therapy in patients with Type 1 Diabetes augments Tregs yet transiently impairs beta-cell function.

Diabetes 2012 Sep;61(9): 2340-2348. PMID: 22721971, PMCID: 3425404.

Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network

[PubMed] [Reprint] [Citation View]
Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network. Rapamycin/IL-2 combination therapy in patients with Type 1 Diabetes augments Tregs yet transiently impairs beta-cell function. Diabetes 2012 Sep;61(9): 2340-2348. PMID: 22721971, PMCID: 3425404..

Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis..

Ann Rheum Dis 2013 Aug; 72(8):1342-50. PMID: 22975753.

Monach PA, Warner RL, Tomasson G, Specks U, Stone JH, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Krischer J, Langford CA, Mueller M, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Johnson KJ, Merkel PA

[PubMed] [Reprint] [Citation View]
Monach PA, Warner RL, Tomasson G, Specks U, Stone JH, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Krischer J, Langford CA, Mueller M, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Johnson KJ, Merkel PA. Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis.. Ann Rheum Dis 2013 Aug; 72(8):1342-50. PMID: 22975753..

Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts.

Am J Transplant 2011 Jul;11(7):1464-77. PMID: 21668634, PMCID: 3128680.

Farris AB, Taheri D, Kawai T, Fazlollahi L, Wong W, Tolkoff-Rubin N, Spitzer TR, Iafrate AJ, Preffer FI, LoCascio SA, Sprangers B, Saidman S, Smith RN, Cosimi AB, Sykes M, Sachs DH, Colvin RB

[PubMed] [Reprint] [Citation View]
Farris AB, Taheri D, Kawai T, Fazlollahi L, Wong W, Tolkoff-Rubin N, Spitzer TR, Iafrate AJ, Preffer FI, LoCascio SA, Sprangers B, Saidman S, Smith RN, Cosimi AB, Sykes M, Sachs DH, Colvin RB. Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts. Am J Transplant 2011 Jul;11(7):1464-77. PMID: 21668634, PMCID: 3128680..

Circulating markers of vascular injury and angiogenesis in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Arthritis Rheum 2011 Dec;63(12):3988-97. PMID: 21953143, PMCID: 3227746.

Monach PA, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Langford CA, Mueller M, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Gu YZ, Snyder RD, Merkel PA

[PubMed] [Reprint] [Citation View]
Monach PA, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Langford CA, Mueller M, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Gu YZ, Snyder RD, Merkel PA. Circulating markers of vascular injury and angiogenesis in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheum 2011 Dec;63(12):3988-97. PMID: 21953143, PMCID: 3227746..

Design of the Rituximab in ANCA-associated Vasculitis (RAVE) Trial.

The Open Arthritis Journal 2011; 4:1-18.

Specks U, Merkel PA, Hoffman GS, Langford CA, Spiera R, Seo P, Kallenberg CGM, St. Clair EW, Ding L, Webber L, Mokhtarani M, Tchao NK, Sayre PH, Seyfert-Margolis V, Ikle D, Brunetta P, Zhang D, Sejismundo L, Mueller M, Stone JH.

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Specks U, Merkel PA, Hoffman GS, Langford CA, Spiera R, Seo P, Kallenberg CGM, St. Clair EW, Ding L, Webber L, Mokhtarani M, Tchao NK, Sayre PH, Seyfert-Margolis V, Ikle D, Brunetta P, Zhang D, Sejismundo L, Mueller M, Stone JH.. Design of the Rituximab in ANCA-associated Vasculitis (RAVE) Trial. The Open Arthritis Journal 2011; 4:1-18..

Donor-specific indirect pathway analysis reveals a B-cell independent signature which reflects outcomes in kidney transplant recipients.

Am J Transplant 2012 Mar; 12(3):640-8. PMID: 22151236, PMCID: 3374729.

Haynes LD, Jankowska-Gan E, Sheka A, Keller MR, Hernandez-Fuentes MP, Lechler RI, Seyfert-Margolis V, Turka LA, Newell KA, Burlingham WJ

[PubMed] [Reprint] [Citation View]
Haynes LD, Jankowska-Gan E, Sheka A, Keller MR, Hernandez-Fuentes MP, Lechler RI, Seyfert-Margolis V, Turka LA, Newell KA, Burlingham WJ. Donor-specific indirect pathway analysis reveals a B-cell independent signature which reflects outcomes in kidney transplant recipients. Am J Transplant 2012 Mar; 12(3):640-8. PMID: 22151236, PMCID: 3374729..

Immuno-intervention for the induction of transplantation tolerance through mixed chimerism.

Semin Immunol 2011 Jun; 23(3):165-173. PMID: 21839648, PMCID: 3178004.

Sachs DH, Sykes M, Kawai T, Cosimi AB

[PubMed] [Reprint] [Citation View]
Sachs DH, Sykes M, Kawai T, Cosimi AB. Immuno-intervention for the induction of transplantation tolerance through mixed chimerism. Semin Immunol 2011 Jun; 23(3):165-173. PMID: 21839648, PMCID: 3178004..

Increased frequencies of myelin oligodendrocyte glycoprotein/MHC Class II-binding CD4 cells in patients with multiple sclerosis.

J Immunol 2011 Jul; 187(2):1039-46. PMID: 21653833, PMCID: 3131477.

Radassi K, Kent SC, Yang J, Bourcier K, Bradshaw EM, Seyfert-Margolis V, Nepom GT, Kwok WW, Hafler DA

[PubMed] [Reprint] [Citation View]
Radassi K, Kent SC, Yang J, Bourcier K, Bradshaw EM, Seyfert-Margolis V, Nepom GT, Kwok WW, Hafler DA. Increased frequencies of myelin oligodendrocyte glycoprotein/MHC Class II-binding CD4 cells in patients with multiple sclerosis. J Immunol 2011 Jul; 187(2):1039-46. PMID: 21653833, PMCID: 3131477..

Long-term follow-up of recipients of combined human leukocyte antigen-matched bone marrow and kidney transplantation for multiple myeloma with end-stage renal disease.

Transplantation 2011; 91(6):672–676. PMID: 21217460, PMCID: 3232059.

Spitzer TR, Sykes M, Tolkoff-Rubin N, Kawai T, McAfee SL, Dey BR, Ballen K, Delmonico F, Saidman S, Sachs DH, Cosimi AB

[PubMed] [Reprint] [Citation View]
Spitzer TR, Sykes M, Tolkoff-Rubin N, Kawai T, McAfee SL, Dey BR, Ballen K, Delmonico F, Saidman S, Sachs DH, Cosimi AB. Long-term follow-up of recipients of combined human leukocyte antigen-matched bone marrow and kidney transplantation for multiple myeloma with end-stage renal disease. Transplantation 2011; 91(6):672–676. PMID: 21217460, PMCID: 3232059..

Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies.

J Allergy Clin Immunol 2011 Feb; 127(2):509-516. PMID: 21281875.

James LK, Shamji MH, Walker SM, Wilson DR, Wachholz PA, Francis JN, Jacobson MR, Kimber I, Till SJ, Durham, SR

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James LK, Shamji MH, Walker SM, Wilson DR, Wachholz PA, Francis JN, Jacobson MR, Kimber I, Till SJ, Durham, SR. Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies. J Allergy Clin Immunol 2011 Feb; 127(2):509-516. PMID: 21281875..

Mechanisms of donor-specific tolerance in recipients of haploidentical combined bone marrow/kidney transplantation.

Am J Transplant 2011; 11(6):1236-1247. PMID: 21645255, PMCID: 3140222.

Andreola G, Chittenden M, Shaffer J, Cosimi AB, Kawai T, Cotter P, LoCascio SA, Morokata T, Dey BR, Preffer F, Bonnefoix T, Kattleman K, Spitzer TR, Sachs DH, Sykes M, Tolkoff-Rubin NT

[PubMed] [Reprint] [Citation View]
Andreola G, Chittenden M, Shaffer J, Cosimi AB, Kawai T, Cotter P, LoCascio SA, Morokata T, Dey BR, Preffer F, Bonnefoix T, Kattleman K, Spitzer TR, Sachs DH, Sykes M, Tolkoff-Rubin NT. Mechanisms of donor-specific tolerance in recipients of haploidentical combined bone marrow/kidney transplantation. Am J Transplant 2011; 11(6):1236-1247. PMID: 21645255, PMCID: 3140222..

Translational studies in hematopoietic cell transplantation: treatment of hematologic malignancies as a stepping stone to tolerance induction.

Semin Immunol 2011 Aug; 23(4):273-281. PMID: 21705229, PMCID: 3201788.

Strober S, Spitzer TR, Sykes M, Lowsky R

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Strober S, Spitzer TR, Sykes M, Lowsky R. Translational studies in hematopoietic cell transplantation: treatment of hematologic malignancies as a stepping stone to tolerance induction. Semin Immunol 2011 Aug; 23(4):273-281. PMID: 21705229, PMCID: 3201788..

Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy.

J Autoimmun 2010 Jun;34(4):408-15. PMID: 19931408, PMCID: 2860016.

Orban T, Farkas K, Jalahej H, Kis J, Treszl A, Falk B, Reijonen H, Wolfsdorf J, Ricker A, Matthews JB, Tchao N, Sayre P, Bianchine P

[PubMed] [Reprint] [Citation View]
Orban T, Farkas K, Jalahej H, Kis J, Treszl A, Falk B, Reijonen H, Wolfsdorf J, Ricker A, Matthews JB, Tchao N, Sayre P, Bianchine P. Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy. J Autoimmun 2010 Jun;34(4):408-15. PMID: 19931408, PMCID: 2860016..

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans.

J Clin Invest 2010 Jun; 120(6):1848-1861. PMID: 20501943, PMCID: 2877932.

Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, Chapman S, Craciun L, Sergeant R, Brouard S, Rovis F, Jimenez E, Ballow A, Giral M, Rebollo-Mesa I, Le Moine A, Braudeau C, Hilton R, Gerstmayer B, Bourcier K, Sharif A, Krajewska M, Lord GM, Roberts I, Goldman M, Wood KJ, Newell K, Seyfert-Margolis V, Warrens AN, Janssen U, Volk HD, Soulillou JP, Hernandez-Fuentes MP, Lechler RI

[PubMed] [Reprint] [Citation View]
Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, Chapman S, Craciun L, Sergeant R, Brouard S, Rovis F, Jimenez E, Ballow A, Giral M, Rebollo-Mesa I, Le Moine A, Braudeau C, Hilton R, Gerstmayer B, Bourcier K, Sharif A, Krajewska M, Lord GM, Roberts I, Goldman M, Wood KJ, Newell K, Seyfert-Margolis V, Warrens AN, Janssen U, Volk HD, Soulillou JP, Hernandez-Fuentes MP, Lechler RI. Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest 2010 Jun; 120(6):1848-1861. PMID: 20501943, PMCID: 2877932..

Identification of a B cell signature associated with renal transplant tolerance in humans.

J Clin Invest 2010 Jun;120(6): 1836-1847. PMID: 20501946, PMCID: 2877933.

Newell KA, Asare A, Kirk AD, Gisler TD, Bourcier K, Suthanthiran M, Burlingham WJ, Marks WH, Sanz I, Lechler RI, Hernandez-Fuentes MP, Turka LA, Seyfert-Margolis VL

[PubMed] [Reprint] [Citation View]
Newell KA, Asare A, Kirk AD, Gisler TD, Bourcier K, Suthanthiran M, Burlingham WJ, Marks WH, Sanz I, Lechler RI, Hernandez-Fuentes MP, Turka LA, Seyfert-Margolis VL. Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest 2010 Jun;120(6): 1836-1847. PMID: 20501946, PMCID: 2877933..

Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance.

Transplantation 2010 Dec; 90(12): 1607-1615. PMID: 21085064, PMCID: 3059844.

LoCascio SA, Morokata T, Chittenden M, Preffer FI, Dombkowski DM, Andreola G, Crisalli K, Kawai T, Saidman Sl, Spitzer TR, Tolkoff-Rubin N, Cosimi BA, Sachs DH, Sykes M

[PubMed] [Citation View]
LoCascio SA, Morokata T, Chittenden M, Preffer FI, Dombkowski DM, Andreola G, Crisalli K, Kawai T, Saidman Sl, Spitzer TR, Tolkoff-Rubin N, Cosimi BA, Sachs DH, Sykes M. Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance. Transplantation 2010 Dec; 90(12): 1607-1615. PMID: 21085064, PMCID: 3059844..

Per-channel basis normalization methods for flow cytometry data.

Cytometry A 2010 Feb;77(2):121-31. PMID: 19899135, PMCID: 3648208.

Hahne F, Khodabakhshi AH, Bashashati A, Wong CJ, Gascoyne RD, Weng AP, Seyfert-Margolis V, Bourcier K, Asare A, Lumley T, Gentleman R, Brinkman RR

[PubMed] [Reprint] [Citation View]
Hahne F, Khodabakhshi AH, Bashashati A, Wong CJ, Gascoyne RD, Weng AP, Seyfert-Margolis V, Bourcier K, Asare A, Lumley T, Gentleman R, Brinkman RR. Per-channel basis normalization methods for flow cytometry data. Cytometry A 2010 Feb;77(2):121-31. PMID: 19899135, PMCID: 3648208..

Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis.

New Eng J Med 2010 Jul;363(3):221-232. PMID: 20647199, PMCID: 3137658.

Stone JH, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Turkiewicz A, Tchao NK, Webber L, Ding L, Sejismundo LP, Mieras K, Weitzenkamp D, Ikle D, Seyfert-Margolis V, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh KA, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Specks U, RAVE-ITN Research Group, Kallenberg C

[PubMed] [Reprint] [Citation View]
Stone JH, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Turkiewicz A, Tchao NK, Webber L, Ding L, Sejismundo LP, Mieras K, Weitzenkamp D, Ikle D, Seyfert-Margolis V, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh KA, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Specks U, RAVE-ITN Research Group, Kallenberg C. Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis. New Eng J Med 2010 Jul;363(3):221-232. PMID: 20647199, PMCID: 3137658..

B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans.

Am J Transplant 2009 Sep;9(9): 2126-35. PMID: 19624570, PMCID: 2837587.

Porcheray F, Wong W, Saidman Sl, De Vito J, Girouard TC, Chittenden M, Shaffer J, Tolkoff-Rubin N, Dey BR, Spitzer TR, Colvin RB, Cosimi AB, Kawai T, Sachs DH, Sykes M, Zorn E

[PubMed] [Reprint] [Citation View]
Porcheray F, Wong W, Saidman Sl, De Vito J, Girouard TC, Chittenden M, Shaffer J, Tolkoff-Rubin N, Dey BR, Spitzer TR, Colvin RB, Cosimi AB, Kawai T, Sachs DH, Sykes M, Zorn E. B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans. Am J Transplant 2009 Sep;9(9): 2126-35. PMID: 19624570, PMCID: 2837587..

Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring.

Am J Transplant 2009 May; 9(5):1087-98. PMID: 19344431.

Knechtle SJ, Pascual J, Bloom DD, Torrealba JR, Jankowska-Gan E, Burlingham WJ, Kwun J, Colvin RB, Seyfert-Margolis V, Bourcier K, Sollinger HW

[PubMed] [Reprint] [Citation View]
Knechtle SJ, Pascual J, Bloom DD, Torrealba JR, Jankowska-Gan E, Burlingham WJ, Kwun J, Colvin RB, Seyfert-Margolis V, Bourcier K, Sollinger HW. Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring. Am J Transplant 2009 May; 9(5):1087-98. PMID: 19344431..
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