Publications

Articles

High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for relapsing-remitting multiple sclerosis (HALT-MS): A 3-year interim report

(2015). JAMA Neurology, 72(2), 159-169. http://dx.doi.org/10.1001/jamaneurol.2014.3780, PMID: 25546364

Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stüve O, Arnold DL, Spychala ME, McConville KC, Harris KM, Phippard D, Georges GE, Wundes A, Kraft GH, Bowen JD

[Reprint] [PubMed] [Citation View]
Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stüve O, Arnold DL, Spychala ME, McConville KC, Harris KM, Phippard D, Georges GE, Wundes A, Kraft GH, Bowen JD (2015). High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for relapsing-remitting multiple sclerosis (HALT-MS): A 3-year interim report. JAMA Neurology, 72(2), 159-169. http://dx.doi.org/10.1001/jamaneurol.2014.3780, PMID: 25546364

Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients

(2015). Science Translational Medicine, 7(272), 272ra10. http://dx.doi.org/10.1126/scitranslmed.3010760, PMID: 25632034, PMCID: PMC4360892

Morris H, DeWolf S, Robins H, Sprangers B, LoCascio SA, Shonts BA, Kawai T, Wong W, Yang S, Zuber J, Shen Y, Sykes M

[Reprint] [PubMed] [Citation View]
Morris H, DeWolf S, Robins H, Sprangers B, LoCascio SA, Shonts BA, Kawai T, Wong W, Yang S, Zuber J, Shen Y, Sykes M (2015). Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients. Science Translational Medicine, 7(272), 272ra10. http://dx.doi.org/10.1126/scitranslmed.3010760, PMID: 25632034, PMCID: PMC4360892

Randomized trial of peanut consumption in infants at risk for peanut allergy.

(2015). N Engl J Med, 372(9), 803-813. http://dx.doi.org/10.1056/NEJMoa1414850, PMID: 25705822, PMCID: PMC4416404

Du Toit G, Roberts G, Sayre PH, Bahnson HT, Radulovic S, Santos AF, Brough HA, Phippard D, Basting M, Feeney M, Turcanu V, Sever ML, Gomez Lorenzo M, Plaut M, Lack G; LEAP Study Team

[Reprint] [PubMed] [Citation View]
Du Toit G, Roberts G, Sayre PH, Bahnson HT, Radulovic S, Santos AF, Brough HA, Phippard D, Basting M, Feeney M, Turcanu V, Sever ML, Gomez Lorenzo M, Plaut M, Lack G; LEAP Study Team (2015). Randomized trial of peanut consumption in infants at risk for peanut allergy.. N Engl J Med, 372(9), 803-813. http://dx.doi.org/10.1056/NEJMoa1414850, PMID: 25705822, PMCID: PMC4416404

Peripheral CD5+ B-cells in antineutrophil cytoplasmic antibody-associated vasculitis.

(2015). Arthritis Rheumatol, 67(2), 535-544. http://dx.doi.org/10.1002/art.38916, PMID: 25332071

Unizony S, Lim N, Phippard DJ, Carey VJ, Miloslavsky EM, Tchao NK, Ikle D, Asare AL, Merkel PA, Monach PA, Seo P, St Clair EW, Langford CA, Spiera R, Hoffman GS, Kallenberg CG, Specks U, Stone JH.

[Reprint] [PubMed] [Citation View]
Unizony S, Lim N, Phippard DJ, Carey VJ, Miloslavsky EM, Tchao NK, Ikle D, Asare AL, Merkel PA, Monach PA, Seo P, St Clair EW, Langford CA, Spiera R, Hoffman GS, Kallenberg CG, Specks U, Stone JH. (2015). Peripheral CD5+ B-cells in antineutrophil cytoplasmic antibody-associated vasculitis.. Arthritis Rheumatol, 67(2), 535-544. http://dx.doi.org/10.1002/art.38916, PMID: 25332071

Effector cell signature in peripheral blood following nasal allergen challenge in grass pollen allergic individuals.

(2015). Allergy, 70(2), 171-179. http://dx.doi.org/10.1111/all.12543, PMID: 25377909

Shamji MH, Bellido V, Scadding GW, Layhadi JA, Cheung DK, Calderon MA, Asare A, Gao Z, Turka LA, Tchao N, Togias A, Phippard D, Durham SR.

[Reprint] [PubMed] [Citation View]
Shamji MH, Bellido V, Scadding GW, Layhadi JA, Cheung DK, Calderon MA, Asare A, Gao Z, Turka LA, Tchao N, Togias A, Phippard D, Durham SR. (2015). Effector cell signature in peripheral blood following nasal allergen challenge in grass pollen allergic individuals.. Allergy, 70(2), 171-179. http://dx.doi.org/10.1111/all.12543, PMID: 25377909

Basophil expression of diamine oxidase: a novel biomarker of allergen immunotherapy response.

(2015). J Allergy Clin Immunol., 135(4), 913-921. http://dx.doi.org/10.1016/j.jaci.2014.09.049, PMID: 25457150

Shamji MH, Layhadi JA, Scadding GW, Cheung DK, Calderon MA, Turka LA, Phippard D, Durham SR

[Reprint] [PubMed] [Citation View]
Shamji MH, Layhadi JA, Scadding GW, Cheung DK, Calderon MA, Turka LA, Phippard D, Durham SR (2015). Basophil expression of diamine oxidase: a novel biomarker of allergen immunotherapy response.. J Allergy Clin Immunol., 135(4), 913-921. http://dx.doi.org/10.1016/j.jaci.2014.09.049, PMID: 25457150

Local and systemic effects of cat allergen nasal provocation.

(2015). Clin Exp Allergy, 45(3), 613-623. http://dx.doi.org/10.1111/cea.12434, PMID: 25303516

Scadding GW, Eifan A, Penagos M, Dumitru A, Switzer A, McMahon O, Phippard D, Togias A, Durham SR, Shamji MH

[Reprint] [PubMed] [Citation View]
Scadding GW, Eifan A, Penagos M, Dumitru A, Switzer A, McMahon O, Phippard D, Togias A, Durham SR, Shamji MH (2015). Local and systemic effects of cat allergen nasal provocation.. Clin Exp Allergy, 45(3), 613-623. http://dx.doi.org/10.1111/cea.12434, PMID: 25303516

An interactive web application for the dissemination of human systems immunology data.

(2015). J Transl Med, 13(196), e-pub. http://dx.doi.org/10.1186/s12967-015-0541-x, PMID: 26088622, PMCID: PMC4474328

Speake C, Presnell S, Domico K, Zeitner B, Bjork A, Anderson D, Mason MJ, Whalen E, Vargas O, Popov D, Rinchai D, Jourde-Chiche N, Chiche L, Quinn C, Chaussabel D

[PubMed] [Citation View]
Speake C, Presnell S, Domico K, Zeitner B, Bjork A, Anderson D, Mason MJ, Whalen E, Vargas O, Popov D, Rinchai D, Jourde-Chiche N, Chiche L, Quinn C, Chaussabel D (2015). An interactive web application for the dissemination of human systems immunology data.. J Transl Med, 13(196), e-pub. http://dx.doi.org/10.1186/s12967-015-0541-x, PMID: 26088622, PMCID: PMC4474328

Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients

(2015). J Clin Invest, e-pub(e-pub), e-pub. http://dx.doi.org/10.1172/JCI81722, PMID: 26193635

Mark R. Rigby, Kristina M. Harris, Ashley Pinckney, Linda A. DiMeglio, Marc S. Rendell, Eric I. Felner, Jean M. Dostou, Stephen E. Gitelman, Kurt J. Griffin, Eva Tsalikian, Peter A. Gottlieb, Carla J. Greenbaum, Nicole A. Sherry, Wayne V. Moore, Roshanak Monzavi, Steven M. Willi, Philip Raskin, Lynette Keyes-Elstein, S. Alice Long, Sai Kanaparthi, Noha Lim, Deborah Phippard, Carol L. Soppe, Margret L. Fitzgibbon, James McNamara, Gerald T. Nepom, Mario R. Ehlers, and the Immune Tolerance Network (ITN) T1DAL Study Group

[PubMed] [Citation View]
Mark R. Rigby, Kristina M. Harris, Ashley Pinckney, Linda A. DiMeglio, Marc S. Rendell, Eric I. Felner, Jean M. Dostou, Stephen E. Gitelman, Kurt J. Griffin, Eva Tsalikian, Peter A. Gottlieb, Carla J. Greenbaum, Nicole A. Sherry, Wayne V. Moore, Roshanak Monzavi, Steven M. Willi, Philip Raskin, Lynette Keyes-Elstein, S. Alice Long, Sai Kanaparthi, Noha Lim, Deborah Phippard, Carol L. Soppe, Margret L. Fitzgibbon, James McNamara, Gerald T. Nepom, Mario R. Ehlers, and the Immune Tolerance Network (ITN) T1DAL Study Group (2015). Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients. J Clin Invest, e-pub(e-pub), e-pub. http://dx.doi.org/10.1172/JCI81722, PMID: 26193635

Neutrophil-Related Gene Expression and Low-Density Granulocytes Associated With Disease Activity and Response to Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

(2015). Arthritis Rheumatol, 67(7), 1922-1932. http://dx.doi.org/10.1002/art.39153, PMID: 25891759, PMCID: PMC4485551

Grayson PC, Carmona-Rivera C, Xu L, Lim N, Gao Z, Asare AL, Specks U, Stone JH, Seo P, Spiera RF, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Ytterberg SR, Phippard DJ, Merkel PA, Kaplan MJ, Monach PA; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group

[PubMed] [Citation View]
Grayson PC, Carmona-Rivera C, Xu L, Lim N, Gao Z, Asare AL, Specks U, Stone JH, Seo P, Spiera RF, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Ytterberg SR, Phippard DJ, Merkel PA, Kaplan MJ, Monach PA; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group (2015). Neutrophil-Related Gene Expression and Low-Density Granulocytes Associated With Disease Activity and Response to Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.. Arthritis Rheumatol, 67(7), 1922-1932. http://dx.doi.org/10.1002/art.39153, PMID: 25891759, PMCID: PMC4485551

T cell repertoire following autologous stem cell transplantation for multiple sclerosis

(2014). J Clin Invest, 124(3), 1168-1172. http://dx.doi.org/10.1172/JCI71691, PMID: 24531550, PMCID: PMC3934160

Muraro PA, Robins H, Malhotra S, Howell M, Phippard D, Desmarais C, de Paula Alves Sousa A, Griffith LM, Lim N, Nash RA, Turka LA

[Reprint] [PubMed] [Citation View]
Muraro PA, Robins H, Malhotra S, Howell M, Phippard D, Desmarais C, de Paula Alves Sousa A, Griffith LM, Lim N, Nash RA, Turka LA (2014). T cell repertoire following autologous stem cell transplantation for multiple sclerosis. J Clin Invest, 124(3), 1168-1172. http://dx.doi.org/10.1172/JCI71691, PMID: 24531550, PMCID: PMC3934160

High-throughput flow cytometry data normalization for clinical trials

(2014). Cytometry A, 85(3), 277-286. PMID: 24382714, PMCID: 3992339

Finak G, Jiang W, Krouse K, Wei C, Sanz I, Phippard D, Asare D, De Rosa SC, Self S, Gottardo R

[Reprint] [PubMed] [Citation View]
Finak G, Jiang W, Krouse K, Wei C, Sanz I, Phippard D, Asare D, De Rosa SC, Self S, Gottardo R (2014). High-throughput flow cytometry data normalization for clinical trials. Cytometry A, 85(3), 277-286. PMID: 24382714, PMCID: 3992339

Restoring the balance: Immunotherapeutic combinations for autoimmune disease

(2014). Disease Models & Mechanisms, 7(5), 503-513. http://dx.doi.org/10.1242/dmm.015099, PMID: 24795433, PMCID: PMC4007402

Smilek DE, Ehers MR, Nepom GT

[Reprint] [PubMed] [Citation View]
Smilek DE, Ehers MR, Nepom GT (2014). Restoring the balance: Immunotherapeutic combinations for autoimmune disease. Disease Models & Mechanisms, 7(5), 503-513. http://dx.doi.org/10.1242/dmm.015099, PMID: 24795433, PMCID: PMC4007402

Targeted immune interventions for type 1 diabetes: Not as easy as it looks!

(2014). Current Opinion in Endocrinology Diabetes and Obesity, 21(4), 271-8. http://dx.doi.org/10.1097/MED.0000000000000075, PMID: 24983393, PMCID: PMC4133939

Rigby MR, Ehlers MR

[Reprint] [PubMed] [Citation View]
Rigby MR, Ehlers MR (2014). Targeted immune interventions for type 1 diabetes: Not as easy as it looks!. Current Opinion in Endocrinology Diabetes and Obesity, 21(4), 271-8. http://dx.doi.org/10.1097/MED.0000000000000075, PMID: 24983393, PMCID: PMC4133939

Rituximab for the Treatment of Relapses in antineutrophil cytoplasmic antibody-associated vasculitis

(2014). Arthritis Rheumatol, 66(11), 3151-3159. http://dx.doi.org/10.1002/art.38788, PMID: 25047592, PMCID: PMC4229846

Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St. Clair EW, Tchao NK, Viviano L, Ding L, Ikle D, Villareal M, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group

[PubMed] [Citation View]
Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St. Clair EW, Tchao NK, Viviano L, Ding L, Ikle D, Villareal M, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group (2014). Rituximab for the Treatment of Relapses in antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheumatol, 66(11), 3151-3159. http://dx.doi.org/10.1002/art.38788, PMID: 25047592, PMCID: PMC4229846

Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy

(2014). J Allergy Clin Immunol, 133(2), 468-475. http://dx.doi.org/10.1016/j.jaci.2013.11.007, PMID: 24361082, PMCID: PMC3960331

Vickery BP, Scurlock AM, Kulis M, Steele PH, Kamilaris J, Berglund JP, Burk C, Hiegel A, Carlisle S, Christie L, Perry TT, Pesek RD, Sheikh S, Virkud Y, Smith PB, Shamji MH, Durham SR, Jones SM, Burks AW

[Reprint] [PubMed] [Citation View]
Vickery BP, Scurlock AM, Kulis M, Steele PH, Kamilaris J, Berglund JP, Burk C, Hiegel A, Carlisle S, Christie L, Perry TT, Pesek RD, Sheikh S, Virkud Y, Smith PB, Shamji MH, Durham SR, Jones SM, Burks AW (2014). Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy. J Allergy Clin Immunol, 133(2), 468-475. http://dx.doi.org/10.1016/j.jaci.2013.11.007, PMID: 24361082, PMCID: PMC3960331

Development of cockroach immunotherapy by the Inner-City Asthma Consortium

(2014). J Allergy Clin Immunol, 133(3), 846-852. http://dx.doi.org/10.1016/j.jaci.2013.08.047, PMID: 24184147, PMCID: PMC3943647

Wood RA, Togias A, Wildfire J, Visness CM, Matsui EC, Gruchalla R, Hershey G, Liu AH, O’Connor GT, Pongracic JA, Zoratti E, Little F, Granada M, Kennedy S, Durham SR, Shamji MH, Busse WW.

[Reprint] [PubMed] [Citation View]
Wood RA, Togias A, Wildfire J, Visness CM, Matsui EC, Gruchalla R, Hershey G, Liu AH, O’Connor GT, Pongracic JA, Zoratti E, Little F, Granada M, Kennedy S, Durham SR, Shamji MH, Busse WW. (2014). Development of cockroach immunotherapy by the Inner-City Asthma Consortium. J Allergy Clin Immunol, 133(3), 846-852. http://dx.doi.org/10.1016/j.jaci.2013.08.047, PMID: 24184147, PMCID: PMC3943647

Magnitude and mechanisms of glucose counterregulation following islet transplantation in patients with type 1 diabetes suffering from severe hypoglycaemic episodes

(2014). Diabetologia, 57(3), 623-632. http://dx.doi.org/10.1007/s00125-013-3120-9, PMID: 24305963

Ang M, Meyer C, Brendel MD, Bretzel RG, Linn T

[PubMed] [Citation View]
Ang M, Meyer C, Brendel MD, Bretzel RG, Linn T (2014). Magnitude and mechanisms of glucose counterregulation following islet transplantation in patients with type 1 diabetes suffering from severe hypoglycaemic episodes. Diabetologia, 57(3), 623-632. http://dx.doi.org/10.1007/s00125-013-3120-9, PMID: 24305963

Ancillary study management systems: a review of needs

(2014). BMC Med Inform Decis Mak, 13(5), 1-17. http://dx.doi.org/10.1186/1472-6947-13-5, PMID: 23294514, PMCID: PMC3564696

Nelson EK, Piehler B, Rauch A, Ramsay S, Holman D, Asare S, Asare A, Igra M

[Reprint] [PubMed] [Citation View]
Nelson EK, Piehler B, Rauch A, Ramsay S, Holman D, Asare S, Asare A, Igra M (2014). Ancillary study management systems: a review of needs. BMC Med Inform Decis Mak, 13(5), 1-17. http://dx.doi.org/10.1186/1472-6947-13-5, PMID: 23294514, PMCID: PMC3564696

Immune-modulating effects of alpha-1 antitrypsin

(2014). Biol Chem, 395(10), 1187-1193. http://dx.doi.org/10.1515/hsz-2014-0161, PMID: 24854541, PMCID: PMC4237306

Ehlers MR

[Reprint] [PubMed] [Citation View]
Ehlers MR (2014). Immune-modulating effects of alpha-1 antitrypsin. Biol Chem, 395(10), 1187-1193. http://dx.doi.org/10.1515/hsz-2014-0161, PMID: 24854541, PMCID: PMC4237306

Treatment of lupus nephritis with abatacept: The Abatacept and Cyclophosphamide Combination Efficacy and Safety Study

(2014). Arthritis & Rheumatology, 66(11), 3096-3104. http://dx.doi.org/10.1002/art.38790, PMID: 25403681

The ACCESS Trial Group

[Reprint] [PubMed] [Citation View]
The ACCESS Trial Group (2014). Treatment of lupus nephritis with abatacept: The Abatacept and Cyclophosphamide Combination Efficacy and Safety Study. Arthritis & Rheumatology, 66(11), 3096-3104. http://dx.doi.org/10.1002/art.38790, PMID: 25403681

Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression.

(2014). Am J Transplant, 14(7), 1599-1611. http://dx.doi.org/10.1111/ajt.12731, PMID: 24903438, PMCID: PMC4228952

Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman Sl, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Gao B, Wong W, Morris H, LoCascio SA, Sayre P, Shonts B, Williams WW, Colvin RB, Smith R-N, Sykes M, Cosimi AB.

[Reprint] [PubMed] [Citation View]
Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman Sl, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Gao B, Wong W, Morris H, LoCascio SA, Sayre P, Shonts B, Williams WW, Colvin RB, Smith R-N, Sykes M, Cosimi AB. (2014). Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression.. Am J Transplant, 14(7), 1599-1611. http://dx.doi.org/10.1111/ajt.12731, PMID: 24903438, PMCID: PMC4228952

Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: Immunologic effects and efficacy in NOD mice

(2013). PLoS One, 8(2), e54712. http://dx.doi.org/10.1371/journal.pone.0054712, PMID: 23405091, PMCID: PMC3566105

Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, Nepom G, Ehlers M, Staeva T, Garren H, Steinman L, Chan AC, von Herrath M

[Reprint] [PubMed] [Citation View]
Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, Nepom G, Ehlers M, Staeva T, Garren H, Steinman L, Chan AC, von Herrath M (2013). Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: Immunologic effects and efficacy in NOD mice. PLoS One, 8(2), e54712. http://dx.doi.org/10.1371/journal.pone.0054712, PMID: 23405091, PMCID: PMC3566105

Estimating the ratio of CD4+ to CD8+ T cells using high-throughput sequence data.

(2013). J Immunol Methods, 391(1-2), 14-21. http://dx.doi.org/10.1016/j.jim.2013.02.002, PMID: 23428915

Emerson R, Sherwood A, Desmarais C, Malhotra S, Phippard D, Robins H

[Reprint] [PubMed] [Citation View]
Emerson R, Sherwood A, Desmarais C, Malhotra S, Phippard D, Robins H (2013). Estimating the ratio of CD4+ to CD8+ T cells using high-throughput sequence data.. J Immunol Methods, 391(1-2), 14-21. http://dx.doi.org/10.1016/j.jim.2013.02.002, PMID: 23428915

HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression

(2013). New Eng L Med, 368(19), 1850-1852. http://dx.doi.org/10.1056/NEJMc121377, PMID: 23656665, PMCID: PMC3760499

Kawai T, Sachs DH, Sykes M, Cosimi BA for the Immune Tolerance Network

[Reprint] [PubMed] [Citation View]
Kawai T, Sachs DH, Sykes M, Cosimi BA for the Immune Tolerance Network (2013). HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression. New Eng L Med, 368(19), 1850-1852. http://dx.doi.org/10.1056/NEJMc121377, PMID: 23656665, PMCID: PMC3760499

Prophylactic use of sublingual allergen immunotherapy in high-risk children: A pilot study

(2013). J Allergy Clin Immunology, 132(4), 991-993. http://dx.doi.org/10.1016/j.jaci.2013.04.049, PMID: 23768574

Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P

[Reprint] [PubMed] [Citation View]
Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P (2013). Prophylactic use of sublingual allergen immunotherapy in high-risk children: A pilot study. J Allergy Clin Immunology, 132(4), 991-993. http://dx.doi.org/10.1016/j.jaci.2013.04.049, PMID: 23768574

Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: Metabolic and immunologic features at baseline identify a subgroup of responders

(2013). Diabetes, 62(11), 3766-3774. http://dx.doi.org/10.2337/db13-0345, PMID: 23835333, PMCID: PMC3806618

Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA, the AbATE Study Team

[Reprint] [PubMed] [Citation View]
Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA, the AbATE Study Team (2013). Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: Metabolic and immunologic features at baseline identify a subgroup of responders. Diabetes, 62(11), 3766-3774. http://dx.doi.org/10.2337/db13-0345, PMID: 23835333, PMCID: PMC3806618

Efficacy of Remission-Induction Regimens for ANCA-Associated Vasculitis

(2013). N Engl J Med, 369(5), 417-427. http://dx.doi.org/10.1056/NEJMoa1213277, PMID: 23902481

Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Fessler BJ, Ding L, Viviano L, Tchao NK, Phippard DJ, Asare AL, Lim N, Ikle D, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Mueller M, Sejismundo LP, Mieras K, Stone JH for the RAVE-ITN Research Group

[Reprint] [PubMed] [Citation View]
Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Fessler BJ, Ding L, Viviano L, Tchao NK, Phippard DJ, Asare AL, Lim N, Ikle D, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Mueller M, Sejismundo LP, Mieras K, Stone JH for the RAVE-ITN Research Group (2013). Efficacy of Remission-Induction Regimens for ANCA-Associated Vasculitis. N Engl J Med, 369(5), 417-427. http://dx.doi.org/10.1056/NEJMoa1213277, PMID: 23902481

Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial

(2013). Lancet Diabetes Endocrinol, 1(4), 306-316. http://dx.doi.org/10.1016/S2213-8587(13)70065-2, PMID: 24622416

Gitelman SE, Gottlieb PA, Rigby MR, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, Ding L, Bluestone JA, Ehlers MR, the START Study Team

[Reprint] [PubMed] [Citation View]
Gitelman SE, Gottlieb PA, Rigby MR, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, Ding L, Bluestone JA, Ehlers MR, the START Study Team (2013). Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial. Lancet Diabetes Endocrinol, 1(4), 306-316. http://dx.doi.org/10.1016/S2213-8587(13)70065-2, PMID: 24622416

Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial

(2013). Lancet Diabetes Endocrinol, 1(4), 284-294. http://dx.doi.org/10.1016/S2213-8587(13)70111-6, PMID: 24622414, PMCID: PMC3957186

Rigby MR, DiMeglio LA, Rendell MS, Felner E, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, and the T1DAL Study Team

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Rigby MR, DiMeglio LA, Rendell MS, Felner E, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, and the T1DAL Study Team (2013). Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Diabetes Endocrinol, 1(4), 284-294. http://dx.doi.org/10.1016/S2213-8587(13)70111-6, PMID: 24622414, PMCID: PMC3957186

Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience

(2013). Rev Diabet Stud, 9(4), 359-371. http://dx.doi.org/10.1900/RDS.2012.9.359, PMID: 23804273, PMCID: PMC3740703

Ehlers MR, Nepom GT

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Ehlers MR, Nepom GT (2013). Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience. Rev Diabet Stud, 9(4), 359-371. http://dx.doi.org/10.1900/RDS.2012.9.359, PMID: 23804273, PMCID: PMC3740703

Clinical Outcomes of Remission Induction Therapy for Severe Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

(2013). Arthritis Rheum, 65(9), 2441-2449. http://dx.doi.org/10.1002/art.38044, PMID: 23754238

Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Tchao NK, Viviano L, Ding L, Sejismundo LP, Mieras K, Ikle D, Jepson B, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH, for the Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group

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Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Tchao NK, Viviano L, Ding L, Sejismundo LP, Mieras K, Ikle D, Jepson B, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH, for the Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group (2013). Clinical Outcomes of Remission Induction Therapy for Severe Antineutrophil Cytoplasmic Antibody–Associated Vasculitis. Arthritis Rheum, 65(9), 2441-2449. http://dx.doi.org/10.1002/art.38044, PMID: 23754238

Proinsulin/insulin autoantibodies measured with electrochemiluminescent assay are the earliest indicator of prediabetic islet autoimmunity

(2013). Diabetes Care, 36(8), 2266-2270. http://dx.doi.org/10.2337/dc12-2245, PMID: 23423694, PMCID: PMC3714529

Yu L, Dong F, Miao D, Fouts AR, Wenzlau JM, Steck AK

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Yu L, Dong F, Miao D, Fouts AR, Wenzlau JM, Steck AK (2013). Proinsulin/insulin autoantibodies measured with electrochemiluminescent assay are the earliest indicator of prediabetic islet autoimmunity. Diabetes Care, 36(8), 2266-2270. http://dx.doi.org/10.2337/dc12-2245, PMID: 23423694, PMCID: PMC3714529

Pre-existing epithelial diversity in normal human livers: A tissue-tethered cytometric analysis in portal/periportal epithelial cells

(2013). Hepatology, 57(4), 1632-1643. http://dx.doi.org/10.1002/hep.26131, PMID: 23150208, PMCID: PMC3612393

Isse K, Lesniak A, Grama K, Maier J, Specht S, Castillo-Rama M, Lunz J, Roysam B, Michalopoulos G, Demetris AJ

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Isse K, Lesniak A, Grama K, Maier J, Specht S, Castillo-Rama M, Lunz J, Roysam B, Michalopoulos G, Demetris AJ (2013). Pre-existing epithelial diversity in normal human livers: A tissue-tethered cytometric analysis in portal/periportal epithelial cells. Hepatology, 57(4), 1632-1643. http://dx.doi.org/10.1002/hep.26131, PMID: 23150208, PMCID: PMC3612393

Type 1 diabetes: primary antigen/peptide/register/trimolecular complex

(2013). Immunol Res, 55(1-3), 270-276. http://dx.doi.org/10.1007/s12026-012-8367-6, PMID: 22956469, PMCID: PMC3936464

Sosinowski T, Eisenbarth GS

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Sosinowski T, Eisenbarth GS (2013). Type 1 diabetes: primary antigen/peptide/register/trimolecular complex. Immunol Res, 55(1-3), 270-276. http://dx.doi.org/10.1007/s12026-012-8367-6, PMID: 22956469, PMCID: PMC3936464

Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants

(2012). JAMA, 307(3), 283-293. http://dx.doi.org/10.1001/jama.2011.2014, PMID: 22253395

Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP, Rosenthal P, Alonso EM, Philogene MC, Ikle D, Poole KM, Bridges ND, Turka LA, Tchao NK

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Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP, Rosenthal P, Alonso EM, Philogene MC, Ikle D, Poole KM, Bridges ND, Turka LA, Tchao NK (2012). Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants. JAMA, 307(3), 283-293. http://dx.doi.org/10.1001/jama.2011.2014, PMID: 22253395

Circulating angiopoietin-2 as a biomarker in ANCA-associated Vasculitis

(2012). PLoS One, 7(1), e30197. http://dx.doi.org/10.1371/journal.pone.0030197, PMID: 22279570, PMCID: 3261176

Monach PA, Kumpers P, Lukasz A, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Carette S, Ding L, Hoffman GS, Ikle D, Kallenberg CG, Khalidi NA, Langford CA, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Haubitz M, Merkel PA

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Monach PA, Kumpers P, Lukasz A, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Carette S, Ding L, Hoffman GS, Ikle D, Kallenberg CG, Khalidi NA, Langford CA, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Haubitz M, Merkel PA (2012). Circulating angiopoietin-2 as a biomarker in ANCA-associated Vasculitis. PLoS One, 7(1), e30197. http://dx.doi.org/10.1371/journal.pone.0030197, PMID: 22279570, PMCID: 3261176

Randomized controlled trial of atorvastatin in clinically isolated syndrome

(2012). Neurology, 78(15), 1171-8. http://dx.doi.org/10.1212/WNL.0b013e31824f7fdd, PMID: 22459680, PMCID: PMC3320055

Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Ikle D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C, Zamvil SS, ITN020AI Study Management Team, ITN STAyCIS Study Group

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Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Ikle D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C, Zamvil SS, ITN020AI Study Management Team, ITN STAyCIS Study Group (2012). Randomized controlled trial of atorvastatin in clinically isolated syndrome. Neurology, 78(15), 1171-8. http://dx.doi.org/10.1212/WNL.0b013e31824f7fdd, PMID: 22459680, PMCID: PMC3320055

Rapamycin/IL-2 combination therapy in Type 1 Diabetes

(2012). Diabetes, 61(9), 2340-2348. PMID: 22721971, PMCID: 3425404

Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network

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Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network (2012). Rapamycin/IL-2 combination therapy in Type 1 Diabetes. Diabetes, 61(9), 2340-2348. PMID: 22721971, PMCID: 3425404

Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes

(2012). J Immunol Methods, 384(1-2), 25-31. PMID: 22759401

Scadding GW, Calderon MA, Bellido V, Koed GK, Nielsen NC, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA

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Scadding GW, Calderon MA, Bellido V, Koed GK, Nielsen NC, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA (2012). Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes. J Immunol Methods, 384(1-2), 25-31. PMID: 22759401

Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study

(2012). J Allergy Clin Immunol, 131(1), 135-143. PMID: 23174658

Du Toit G, Roberts G, Sayre PH, Plaut M, Bahnson HT, Mitchell H, Radulovic S, Chan S, Fox A, Turcanu V, Lack G

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Du Toit G, Roberts G, Sayre PH, Plaut M, Bahnson HT, Mitchell H, Radulovic S, Chan S, Fox A, Turcanu V, Lack G (2012). Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study. J Allergy Clin Immunol, 131(1), 135-143. PMID: 23174658

QUAliFiER: An automated pipeline for quality assessment of gated flow cytometry data

(2012). BMC Bioinformatics, Sep(13), 252. PMID: 23020243, PMCID: 3499158

Finak G, Jiang W, Pardo J, Asare A, Gottardo R

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Finak G, Jiang W, Pardo J, Asare A, Gottardo R (2012). QUAliFiER: An automated pipeline for quality assessment of gated flow cytometry data. BMC Bioinformatics, Sep(13), 252. PMID: 23020243, PMCID: 3499158

Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis.

(2012). Ann Rheum Dis, 72(8), 1342-1350. PMID: 22975753

Monach PA, Warner RL, Tomasson G, Specks U, Stone JH, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Krischer J, Langford CA, Mueller M, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Johnson KJ, Merkel PA

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Monach PA, Warner RL, Tomasson G, Specks U, Stone JH, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Krischer J, Langford CA, Mueller M, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Johnson KJ, Merkel PA (2012). Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis.. Ann Rheum Dis, 72(8), 1342-1350. PMID: 22975753

Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy

(2012). Allergy, 62(2), 217-226. PMID: 22077562

Shamji MH, Ljorring C, Francis JN, Calderon MA, Larché M, Kimber I, Frew AJ, Ipsen H, Lund K, Wurtzen PA, Durham SR

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Shamji MH, Ljorring C, Francis JN, Calderon MA, Larché M, Kimber I, Frew AJ, Ipsen H, Lund K, Wurtzen PA, Durham SR (2012). Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy. Allergy, 62(2), 217-226. PMID: 22077562

Long term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies

(2011). J Allergy Clin Immunol, 127(2), 509-516. PMID: 21281875

James LK, Shamji MH, Walker SM, Wilson DR, Wachholz PA, Francis JN, Jacobson MR, Kimber I, Till SJ, Durham, SR

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James LK, Shamji MH, Walker SM, Wilson DR, Wachholz PA, Francis JN, Jacobson MR, Kimber I, Till SJ, Durham, SR (2011). Long term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies. J Allergy Clin Immunol, 127(2), 509-516. PMID: 21281875

Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts

(2011). Am J Transplant, 11(7), 1464-1477. PMID: 21668634, PMCID: PMC3128680

Farris AB, Taheri D, Kawai T, Fazlollahi L, Wong W, Tolkoff-Rubin N, Spitzer TR, Iafrate AJ, Preffer FI, LoCascio SA, Sprangers B, Saidman S, Smith RN, Cosimi AB, Sykes M, Sachs DH, Colvin RB

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Farris AB, Taheri D, Kawai T, Fazlollahi L, Wong W, Tolkoff-Rubin N, Spitzer TR, Iafrate AJ, Preffer FI, LoCascio SA, Sprangers B, Saidman S, Smith RN, Cosimi AB, Sykes M, Sachs DH, Colvin RB (2011). Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts. Am J Transplant, 11(7), 1464-1477. PMID: 21668634, PMCID: PMC3128680

Increased frequencies of myelin oligodendrocyte glycoprotein/MHC Class II-binding CD4 cells in patients with multiple sclerosis

(2011). J Immunol, 187(2), 1039-46. PMID: 21653833, PMCID: 3131477

Radassi K, Kent SC, Yang J, Bourcier K, Bradshaw EM, Seyfert-Margolis V, Nepom GT, Kwok WW, Hafler DA

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Radassi K, Kent SC, Yang J, Bourcier K, Bradshaw EM, Seyfert-Margolis V, Nepom GT, Kwok WW, Hafler DA (2011). Increased frequencies of myelin oligodendrocyte glycoprotein/MHC Class II-binding CD4 cells in patients with multiple sclerosis. J Immunol, 187(2), 1039-46. PMID: 21653833, PMCID: 3131477

Design of the Rituximab in ANCA-associated Vasculitis (RAVE) Trial

(2011). The Open Arthritis Journal, 4(1), 1-18.

Specks U, Merkel PA, Hoffman GS, Langford CA, Spiera R, Seo P, Kallenberg CGM, St. Clair EW, Ding L, Webber L, Mokhtarani M, Tchao NK, Sayre PH, Seyfert-Margolis V, Ikle D, Brunetta P, Zhang D, Sejismundo L, Mueller M, Stone JH

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Specks U, Merkel PA, Hoffman GS, Langford CA, Spiera R, Seo P, Kallenberg CGM, St. Clair EW, Ding L, Webber L, Mokhtarani M, Tchao NK, Sayre PH, Seyfert-Margolis V, Ikle D, Brunetta P, Zhang D, Sejismundo L, Mueller M, Stone JH (2011). Design of the Rituximab in ANCA-associated Vasculitis (RAVE) Trial. The Open Arthritis Journal, 4(1), 1-18.

Circulating markers of vascular injury and angiogenesis in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

(2011). Arthritis Rheum, 36(12), 3988-3997. PMID: 21953143, PMCID: 3227746

Monach PA, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Langford CA, Mueller M, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Gu YZ, Snyder RD, Merkel PA

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Monach PA, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Langford CA, Mueller M, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Gu YZ, Snyder RD, Merkel PA (2011). Circulating markers of vascular injury and angiogenesis in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheum, 36(12), 3988-3997. PMID: 21953143, PMCID: 3227746

Donor-specific indirect pathway analysis reveals a B-cell independent signature which reflects outcomes in kidney transplant recipients

(2011). Am J Transplant, 12(3), 640-8. PMID: 22151236, PMCID: 3374729

Haynes LD, Jankowska-Gan E, Sheka A, Keller MR, Hernandez-Fuentes MP, Lechler RI, Seyfert-Margolis V, Turka LA, Newell KA, Burlingham WJ

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Haynes LD, Jankowska-Gan E, Sheka A, Keller MR, Hernandez-Fuentes MP, Lechler RI, Seyfert-Margolis V, Turka LA, Newell KA, Burlingham WJ (2011). Donor-specific indirect pathway analysis reveals a B-cell independent signature which reflects outcomes in kidney transplant recipients. Am J Transplant, 12(3), 640-8. PMID: 22151236, PMCID: 3374729
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