A clinical research consortium sponsored by NIAID and JDRF
Researchers, doctors and patients

Clinical Trials for Transplantation

Gradual Withdrawal of Immunosuppression in Patients Receiving a Liver Transplant (AWISH)

In order to prevent organ rejection, patients receiving liver transplants currently require life-long treatment with immune system-suppressing medications. However, these medications can cause long-term side effects, such as infection, kidney problems, diabetes, and cancer. This study is investigating whether liver transplant recipients can slowly be taken off these drugs under medical supervision.
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ITN Registry of Tolerant Kidney Transplant Recipients

Immunosuppressive drugs are all that separate transplant recipients from rejecting their transplanted organs. The ITN Registry of Tolerant Kidney Transplant Recipients is searching for those rare kidney transplant recipients who have stopped their immunosuppression, but for some reason have not rejected their transplants. If you have received a kidney transplant and have been off all immunosuppressive medications for 1 year and have good kidney function, or if you received your kidney from an identical twin, you may be eligible to participate. 


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Renal Allograft Tolerance through Mixed Chimerism

Summary coming soon.
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An Observational Study to Assess the Prevalence of a Tolerance Signature in Renal Transplant Recipients (ARTIST)

Summary coming soon.