Tolerance Assay Research Studies

Assay Development

Follow-up of individual T cell mobilization through TCR integration
Principal Investigator: Jean-Paul Soulillou, Institut National de la Sante, Nantes, France

Monitoring of CMV-specific T cells following tolerance induction protocols
Principal Investigator: Florian Kern, Institut für Medizinische Immunologie, Berlin, Germany

Type 1 Diabetes Consortium (Pilot 2)
Principal Investigator: Vicki Seyfert, Immune Tolerance Network, Bethesda, MD

Multiple Sclerosis Consortium
Principal Investigator: Vicki Seyfert, Immune Tolerance Network, Bethesda, MD

Targeted Studies

ITN Tolerant Kidney Patient Registry
Principal Investigator: Kenneth Newell, Emory University, Atlanta, GA

Cytokine production in blood leukocytes of prediabetic children and effect of intranasal insulin
Principal Investigator: Jorma Ilonen, University of Turku, Turku, Finland

Development of antigen-specific assays to detect donor specific tolerance in renal transplant recipients
Principal Investigator: Robert Lechler, Imperial College School of Medicine, UK

Anti-HLA antibody status in islet transplant recipients
Principal Investigator: Miriam Segall, University of Minnesota

Mechanistic studies of altered peptide ligand treatment for multiple sclerosis
Principal Investigator: Jack Antel, Montreal Neurological Institute, Montreal, Canada

Immunological studies of TCR peptide vaccination in Multiple Sclerosis
Principal Investigator: Dennis Bourdette, Oregon Health Sciences University, Portland, OR

In vitro correlates of liver transplant tolerance in patients off immunosuppression
Principal Investigator: Angus Thomson, University of Pittsburgh Medical Center, Pittsburgh, PA

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