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Islet Transplantation Research
| Information for the General Public |

Trials Currently Enrolling

Studies listed below are currently or will soon be recruiting patients. Links displaying the Open in new windowicon will take you to the study listing on clinicaltrials.gov. In some cases, links to additional information (beyond that which is provided on clinicaltrials.gov) are provided.

If you would like to be notified when new trial listings are added, subscribe to the ITN Mailing List.

TYPE 1 DIABETES

The AbATE Type 1 Diabetes Trial - hOKT3g1(Ala-Ala) for new onset diabetes Opens in new window
Conditions: Recently diagnosed type 1 diabetes

Natural History Study of the Development of Type 1 Diabetes (TrialNet) Opens in new window
Conditions: people at increased risk for type 1 diabetes

Oral Insulin for Prevention of Type 1 Diabetes (TrialNet) Opens in new window
Conditions: people at increased risk for type 1 diabetes

The Rituximab Study (TrialNet) Opens in new window
Conditions: Recently diagnosed with type 1 diabetes

OTHER AUTOIMMUNE DISEASES

Psoriatic Arthritis Research and Treatment (PART) Studyopens in new window
Conditions: Psoriatic Arthritis

STAyCIS - Statins (Atorvastatin) for treatment of patients With Clinically Isolated Syndrome and High Risk of Multiple Sclerosis
Conditions: Multiple Sclerosis; Clinically Isolated Syndrome

Rituximab for the Treatment of ANCA-associated vasulitis
Conditions: Wegener's Granulomatosis and Microscopic Polyangiitis

TRANSPLANTATION

Donor Stem Cells and Campath 1H to Prevent Organ Rejection in Kidney Transplantation Open in new window
Condition: Kidney Transplantation

The ITN Registry of Tolerant Kidney Transplant Recipients
Conditions: Kidney Transplantation

BESTT: Belatacept Efficacy, Safety and Transplant Tolerance Open in new window
Conditions: Kidney Transplantation

Safety of Withdrawing Immunosuppressive Drugs in Children Who Have Received a Liver Transplant Open in new window
Conditions: Pediatric Liver Transplantation

Gradual Withdrawal of Immunosuppression in Adult Liver Transplantation Open in new window
Conditions: Liver Transplantation

ASTHMA/ALLERGY

The LEAP Study: Prevention of peanut allergy in high-risk children with eczema and/or egg allergy opens in a new window
Conditions: Eczema, egg allergy, peanut allergy

GPAC: Global Prevention of Asthma in Children opens in a new window
Conditions: Eczema, allergy, asthma

                                     

Trials no longer enrolling patients

Multicenter trial of the Edmonton Protocol for islet transplantation in Type 1 diabetes mellitus
Principal Investigator: James Shapiro, University of Alberta

A Phase I Study: Safety of One Dose Of RG2077 (CTLA4-IgG4m) in Patients With Relapsing-Remitting Multiple Sclerosis
Conditions: Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting

Efficacy and Safety Evaluation of Allergen Immunotherapy Co-Administered With Omalizumab, an Anti-IgE Monoclonal Antibody
Conditions: Hay Fever; Hypersensitivity; Allergy; Rhinitis

Evaluation of a Diabetes Vaccine in Newly Diagnosed Type I Diabetics
Conditions: Insulin-Dependent Diabetes Mellitus; Diabetes Mellitus

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability and Efficacy of NBI-5788 in Patients with Relapsing Multiple SclerosisOpen in new window
Condition: Multiple Sclerosis

The AIRIA Study: Allergen-immunostimulatory sequences for ragweed-induced asthmaopens in a new window
Conditions: Asthma, ragweed allergy (hay fever)

Renal Allograft Tolerance Through Mixed ChimerismOpen in new window
Conditions: Kidney Failure; Kidney Transplantation; Kidney Failure, Chronic

Combined HLA-matched Bone Marrow and Kidney Transplantation for Multiple Myeloma with Renal FailureOpen in new window
Conditions: Kidney transplantation; Kidney Failure, Chronic; Multiple Myeloma

Campath-1H/Tacrolimus/Sirolimus Withdrawal in Renal TransplantationOpen in new window
Condition: Kidney Transplantation

Treating Systemic Lupus Erythematosus Patients with CTLA4-IgG4m (RG2077)
Conditions: Lupus Erythematosus, Systemic; Lupus Nephritis

In addition, current listings of clinical trials for many, many conditions, please visit: www.clinicaltrials.gov or check the Other Resources section for more information on enrolling in clinical trials.

 

 

 



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