Articles

Mathieu C, Wiedeman A, Cerosaletti K, Long SA, Serti E, Cooney L, Vermeiren J, Caluwaerts S, Van Huynegem K, Van Huynegem K, Steidler L, Blomme S, Rottiers P, Nepom GT, Herold KC, AG019-T!D-101 Trial Investigators (2024). A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab. Diabetologia, 67 (1), 27-41.

http://dx.doi.org/10.1007/s00125-023-06014-2

PMID: 

37782353

PMCID: 

PMC10709251

Du Toit G, Huffaker MF, Radulovic S, Feeney M, Fisher HR, Byron M, Dunaway L, Calatroni A, Johnson M, Foong RX, Marques-Mejias A, Bartha I, Basting M, Brough HA, Baloh C, Laidlaw TM, Bahnson HT, Roberts G, Plaut M, Wheatley LM, Lack G, Immune Tolerance Network LEAP-Trio Trial Team (2024). Follow-up to Adolescence after Early Peanut Introduction for Allergy Prevention. NEJM Evid, Epub ahead of print.

http://dx.doi.org/10.1056/EVIDoa2300311

PMID: 

38804779

PMCID: 

Markmann JF, Burrell BE, Bromberg JS, Hartono C, Kaufman DB, Possselt AM, Naji A, Bridges ND, Breeden C, Kanaparthi S, Pardo J, Kopetskie H, Mason K, Lim N, Chandran S. (2024). Immunosuppression withdrawal in living-donor renal transplant recipients following induction with antithymocyte globulin and rituximab: Results of a prospective clinical trial. Am J Transplant., Epub ahead of print.

http://dx.doi.org/10.1016/j.ajt.2024.03.007

PMID: 

38467375

PMCID: 

Higdon LE, Scheiding S, Kus AM, Lim N, Long SA, Anderson MS, Wiedeman AE. (2024). Impact on in-depth immunophenotyping of delay to peripheral blood processing. Clin Exp Immunol, Epub.

http://dx.doi.org/10.1093/cei/uxae041

PMID: 

38693758

PMCID: 

Witkop, EM. Diggins, K. Weideman, A. Serti, E. Nepom, G. Gersuk, VH. Fuchs, B. Long, SA. Linsley, PS. (2024). Interconnected lineage trajectories link conventional and natural killer (NK)-like exhaustedCD8+ T cells beneficial in type 1 diabetes. Communications biology, 7 (1), 773.

http://dx.doi.org/10.1038/s42003-024-06456-3

PMID: 

38937521

PMCID: 

PMC11211332

Roberts, G. Bahnson. HT. Du Toit, G. O’Rourk, C. Sever, M, Brittain, E. Plaut, M. Lack, G. (2023). Defining the window of opportunity and the target populations to prevent peanut allergy. J Allergy Clin Immunol., 151 (5), 1329-1336.

http://dx.doi.org/10.1016/j.jaci.2022.09.042

PMID: 

36521802

PMCID: 

PMC10689252

Suprun M, Bahnson HT, Du Toit G, Lack G, Suarez-Farinas M, Sampson HA. (2023). In children with eczema, expansion of epitope-specific IgE is associated with peanut allergy at 5 years of age. Allergy, 78 (2), 586-589.

http://dx.doi.org/10.1111/all.15572

PMID: 

36321870

PMCID: 

Baloh CH, Kanchan K, Shankar G, Nepom GT, Mathias RA, Perry JA. (2023). Omics-Oriented Research illustrated with the LEAP Study and the OASIS Bioinformatics Tool. The Journal of Allergy and Clinical Immunology, 151 (2), 416-419.

Sever ML, Calatroni A, Roberts G, Du Toit G, Bahnson HT, Radulovic S, Larson D, Byron M, Santos AF, Huffaker MF, Wheatley LM, Lack G. (2023). Developing a Prediction Model for Determination of Peanut Allergy Status in the LEAP Studies. J Allergy Clin Immunol Pract, Epub ahead of print.

Logan K, Bahnson HT, Ylescupidez A, Beyer K, Bellach J, Campbell DE, Craven J, Du Toit G, Clare Mills EN, Perkin MR, Roberts G, van Ree R, Lack G (2023). Early introduction of peanut reduces peanut allergy across risk groups in pooled and causal inference analyses. Allergy, 78 (5), 1307-1318.

http://dx.doi.org/10.1111/all.15597

PMID: 

36435990

PMCID: 

Altman MC, Segnitz RM, Larson D, Jayavelu ND, Smith MT, Patel S, Scadding GW, Qin T, Sanda S, Steveling E, Eifan AO, Penagos M, Jacobson MR, Parkin RV, Shamji MH, Togias A, Durham SR (2023). Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy. J Allergy Clin Immunol, 152 (5), 1247-1260.

http://dx.doi.org/10.1016/j.jaci.2023.06.025

PMID: 

37460024

PMCID: 

PMC10788383

Berti A, Hillion S, Konig MF, Casal Moura M, Hummel AM, Carmona E, Peikert T, Fervenza FC, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, Brunetta P, St Clair EW, Harris KM, Stone JH, Grandi G, Pers JO, Specks U, Cornec D. (2023). Autoreactive plasmablasts after B cell depletion with rituximab and relapses in ANCA-associated vasculitis. Arthritis Rheumatol, 75 (5), 736-747.

http://dx.doi.org/10.1002/art.42388

PMID: 

36281741

PMCID: 

PMC10280646

Moura MC, Thompson GE, Nelson DR, Fussner LA, Hummel AM, Jenne DE, Emerling D, Fervenza FC, Kallenberg CGM, Langford CA, McCune WJ, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, Stone JH, Robinson WH, Specks U (2023). Activation of a Latent Epitope Causing Differential Binding of Anti-Neutrophil Cytoplasmic Antibodies to Proteinase 3. Arthritis Rheumatol, 75 (5), 748-759.

http://dx.doi.org/10.1002/art.42418

PMID: 

36515151

PMCID: 

PMC10191989

Odler B, Riedl R, Gauckler P, Shin JI, Leierer J, Merkel PA, St Clair W, Fervenza F, Geetha D, Monach P, Jayne D, Smith RM, Rosenkranz A, Specks U, Stone JH, Kronbichler A; RAVE−ITN Research Group. (2023). Risk factors for serious infections in ANCA-associated vasculitis. Annals of the Rheumatic Diseases, 82 (5), 681-687.

http://dx.doi.org/0.1136/ard-2022-223401

PMID: 

36702528

PMCID: 

PMC10176387

Russell WE, Bundy BN, Anderson MS, Cooney LA, Gitelman SE, Goland RS, Gottlieb PA, Greenbaum CJ, Haller MJ, Krischer JP, Libman IM, Linsley PS, Long SA, Lord SM, Moore DJ, Moore WV, Moran AM, Muir AB, Raskin P, Skyler JS, Wentworth JM, Wherrett DK, Wilson DM, Ziegler AG, Herold KC; Type 1 Diabetes TrialNet Study Group. (2023). Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial. Diabetes Care., 46 (5), 1005-1013.

http://dx.doi.org/10.2337/dc22-2200

PMID: 

36920087

PMCID: 

PMC10154649

Sykes M, Chandran S, Kawai T, Levitsky J, Mapara M, Mathew J, Thomson A, Yamada K. (2023). Meeting Report: The Fifth International Samuel Strober Workshop on Clinical Immune Tolerance. Transplantation, 107 (3), 564-569.

Duan, M., Nguyen, D. C., Joyner, C. J., Saney, C. L., Tipton, C. M., Andrews, J., Lonial, S., Kim, C., Hentenaar, I., Kosters, A., Ghosn, E., Jackson, Knechtle, Maruthamuthu, Chandran, Martin, T., Rajalingam, R., Vincenti, F., Breeden, Sanz, Gibson, G., Lee, F. E. (2023). Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses. Cell Reports, 42 (7), 112682.

http://dx.doi.org/10.1016/j.celrep.2023.112682

PMID: 

37355988

PMCID: 

PMC10391632

Balmas E, Chen J, Hu AK, DeBerg HA, Rosasco MG, Gersuk VH, Serti E, Speake C, Greenbaum CJ, Nepom GT, Linsley P. Cerosaletti (2023). Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes. JCI Insight, 8 (21), e167881.

http://dx.doi.org/10.1172/jci.insight.167881

PMID: 

37751304

PMCID: 

PMC10721267

Delgado AL, Preston-Hurlburt P, Lim N, Sumida TS, Long SA, McNamara J, Serti E, Higdon L, Herold KC (2023). Latent EBV impairs immune cell signaling and enhances the efficacy of anti-CD3 mAb in Type 1 Diabetes. medRxiv, Epub ahead of print.

http://dx.doi.org/10.1101/2023.07.11.23292344

PMID: 

37502867

PMCID: 

PMC10370230

Narsale A, Almanza F, Tran T, Lam B, Seo D, Vu A, Long SA, Cooney L, Serti E, Davies JD (2023). Th2 cell clonal expansion at diagnosis in human type 1 diabetes. Clinical Immunology, 257, 109829.

Linsley P, Nakayama M, Balmas E, Chen J, Pour F, Bansal S, Serti E, Speake C, Pugliese A, Cerosaletti K (2023). Self-reactive germline-like TCR alpha chains shared between blood and pancreas. Res Sq, NLM Preprint.

http://dx.doi.org/10.21203/rs.3.rs-3446917/v1

PMID: 

37886513

PMCID: 

PMC10602137

Calise J, DeBerg HA, Garabatos N, Khosa S, Bajzik V, Botero Calderon L, Aldridge K, Rosasco M, Ferslew BC, Zhu T, Smulders R, Wheatley LM, Laidlaw TM, Qin T, Chichili GR, Adelman DC, Farrington M, Robinson D, Jeong D, Jones SM, Sanda S, Larson D, Kwok WW, Baloh C, Nepom GT, Wambre E, IMPACT investigators (2023). Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy. J Allergy Clin Immunol, 152 (1), 155-166.e9.

http://dx.doi.org/10.1016/j.jaci.2023.03.020

PMID: 

37003475

PMCID: 

PMC10330178

Jones SM, Nadeau KC, Nowak-Węgrzyn A, Wood RA, Sampson HA, Scurlock AM, Chinthrajah RS, Wang J, Pesek RD, Sindher SB, Kulis M, Spain K, Babineau DC, Chin H, Laurienzo-Panza J, Yan R, Qin T, Whitehouse D, Sever ML, Sanda S, Plaut M, Wheatley LM, Burks AW, Immune Tolerance Network (2022). Efficacy and safety of oral immunotherapy in children aged 1-3 years with peanut allergy (the Immune Tolerance Network IMPACT trial): a randomised placebo-controlled study. Lancet, 399 (10322), 359-371.

http://dx.doi.org/10.1016/S0140-6736(21)02390-4

PMID: 

35065784

PMCID: 

PMC9119642

Kanchan K, Grinek S, Bahnson HT, Ruczinski I, Shankar G, Larson D, Du Toit G, Barnes KC, Sampson HA, Suarez-Farinas M, Lack G, Nepom GT, Cerosaletti K, Mathias RA (2022). HLA alleles and sustained peanut consumption promote IgG4 responses in subjects protected from peanut allergy. J Clin Invest, 132 (1).

http://dx.doi.org/10.1172/JCI152070

PMID: 

34981778

PMCID: 

PMC8718139

Bajzik V, DeBerg HA, Garabatos N, Rust BJ, Obrien KK, Nguyen QA, O'Rourke C, Smith A, Walker AH, Quinn C, Gersuk VH, Farrington M, Jeong D, Vickery BP, Adelman DC, Wambre E (2022). Oral desensitization therapy for peanut allergy induces dynamic changes in peanut-specific immune responses. Allergy, Epub ahead of print.

http://dx.doi.org/doi.org/10.1111/all.15276

PMID: 

35266148

PMCID: 

Brough HA, Lanser BJ, Sindher SB, Teng JMC, Leung DYM, Venter C, Chan SM, Santos AF, Bahnson HT, Guttman-Yassky E, Gupta RS, Lack G, Ciaccio CE, Sampath V, Nadeau KC, Nagler CR. (2022). Early intervention and prevention of allergic diseases. Allergy, 77 (2), 416-441.

http://dx.doi.org/10.1111/all.15006

PMID: 

34255344

PMCID: 

Corren J, Larson D, Altman MC, Segnitz RM, Avila PC, Greenberger PA, Baroody F, Moss MH, Nelson H, Burbank AJ, Hernandez ML, Peden D, Saini S, Tilles S, Hussain I, Whitehouse D, Qin T, Villarreal M, Sever M, Wheatley LM, Nepom GT, Sanda S. (2022). Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: a randomized controlled trial. Journal of Allergy and Clinical Immunology.

PMID: 

36223848

PMCID: 

Smeekens JM, Baloh C, Lim N, Larson D, Qin T, Wheatley L, Kim EH, Jones SM, Burks AW, Kulis MD. (2022). Peanut-Specific IgG4 and IgA in Saliva Are Modulated by Peanut Oral Immunotherapy. The Journal of Allergy and Clinical Immunology, Epub ahead of print.

Grinek S, Suprun M, Raghunathan R, Tomalin LE, Getts R, Bahnson T, Lack G, Sampson HA, Suarez-Farinas M. (2022). Epitope-Specific IgE at 1 Year of Age Can Predict Peanut Allergy Status at 5 Years. Int Arch Allergy Immunol., Epub ahead of print, 1-6.

http://dx.doi.org/10.1159/000526364

PMID: 

36502801

PMCID: 

Monach PA, Warner RL, Lew R, Tomasson G, Specks U, Stone JH, Fervenza FC, Hoffman GS, Kallenberg CGM, Langford CA, Seo P, St Clair EW, Spiera R, Johnson KJ, Merkel PA (2022). Serum Biomarkers of Disease Activity in Longitudinal Assessment of Patients with ANCA-Associated Vasculitis. ACR Open Rheumatology, 4 (2), 168-176.

http://dx.doi.org/doi.org/10.1002/acr2.11366

PMID: 

34792864

PMCID: 

PMC8843765

Gamerith G, Mildner F, Merkel PA, Harris K, Cooney L, Lim N, Spiera R, Seo P, Langford CA, Hoffman GS, St Clair EW, Fervenza FC, Monach P, Ytterberg SR, Geetha D, Amann A, Wolf D, Specks U, Stone JH, Kronbichler A (2022). Association of baseline soluble immune checkpoints with the risk of relapse in PR3-ANCA vasculitis following induction of remission. Ann Rheum Dis, Epub ahead of print.

http://dx.doi.org/10.1136/ard-2022-222479

PMID: 

35973802

PMCID: 

Mexhitaj I, Lim N, Fernandez-Velasco JI, Zrzavy T, Harris KM, Muraro PA, Villar LM, Bar-Or A, Cooney LA. (2022). Stabilization of leukocytes from cerebrospinal fluid for central immunophenotypic evaluation in multicenter clinical trials. J Immunol Methods, Epub ahead of print.

http://dx.doi.org/10.1016/j.jim.2022.113344

PMID: 

36041516

PMCID: 

Shimozawa K, Contreras-Ruiz L, Sousa S, Zhang R, Bhatia U, Crisalli KC, Brennan LL, Turka LA, Markmann JF, Guinan EC. (2022). Ex vivo generation of regulatory T cells from liver transplant recipients using costimulation blockade. Am J Transplant, 22 (2), 504-518.

http://dx.doi.org/10.1111/ajt.16842

PMID: 

34528383

PMCID: 

PMC9078620

Wood-Trageser MA, Lesniak D, Gambella A, Golnoski K, Feng S, Bucuvalas J, Sanchez-Fueyo A, Demetris AJ (2022). Next Generation Pathology Detection of T cell-Antigen Presenting Cell Immune Synapses in Human Liver Allografts. Hepatology, 77 (2), 355-366.

http://dx.doi.org/10.1002/hep.32666

PMID: 

35819312

PMCID: 

PMC9834436

Tang, Q. Leung, J. Peng, Y. Sanchez-Fueyo, A. Lozano, JJ. Lam, A. Lee, K. Greenland, JR. Hellerstein, M. Fitch, M. Li, KW. Esensten, JH. Putnam, AL. Lares, A. Nguyen, V. Liu, W. Bridges, ND. Odim, J. Demetris, AJ. Levitsky, J. Taner, T. Feng, S. (2022). Selective decrease of donor-reactive Tregs after liver transplantation limits Treg therapy for promoting allograft tolerance in humans. Sci Transl Med, 14, 669.

Perito ER, Persyn E, Bucuvalas J, Martinez M, Mohammad S, Squires JE, Demetris AJ, Feng S. (2022). Graft Fibrosis Over 10 to 15 Years in Pediatric Liver Transplant Recipients: Multicenter Study of Paired, Longitudinal Surveillance Biopsies. Liver Transplantation, 28 (6), 1051-1062.

http://dx.doi.org/10.1002/lt.26409

PMID: 

35029022

PMCID: 

Hübscher SG, Feng S, Gouw ASH, Haga H, Kang HJ, Kelly DA, Komuta M, Lesniak A, Popp BA, Verkade HJ, Yu E, Demetris AJ. (2022). Standardizing the histological assessment of late posttransplantation biopsies from pediatric liver allograft recipients. Liver Transplantation, 28 (9), 1475-1489.

http://dx.doi.org/10.1002/lt.26482

PMID: 

35429359

PMCID: 

Marwaha AK, Chow S, Pesenacker AM, Cook L, Sun A, Long SA, Yang JHM, Ward-Hartstonge KA, Williams E, Domingo-Vila C, Halani K, Harris KM, Tree TIM, Levings MK, Elliott T, Tan R, Dutz JP (2022). A phase 1b open-label dose-finding study of ustekinumab in young adults with type 1 diabetes. Immunotherapy Advances, 2 (1), 1 -13.

http://dx.doi.org/10.1093/immadv/ltab022

PMID: 

35072168

PMCID: 

PMC8769169

Speake C, Habib T, Lambert K, Hundhausen C, Lord S, Dufort MJ, Skinner SO, Hu A, Kinsman M, Jones BE, Maerz MD, Tatum M, Hocking AM, Nepom GT, Greenbaum CJ, Buckner JH (2022). IL-6-targeted therapies directed to cytokine or receptor blockade drive distinct alterations in T cell function. JCI Insight, 7 (22), e159436.

http://dx.doi.org/10.1172/jci.insight.159436

PMID: 

36282595

PMCID: 

PMC9746808

Shamji MH, Larson D, Eifan A, Scadding GW, Qin T, Lawson K, Sever ML, Macfarlane Ellen, Layhadi JA, Wurtzen PA, Parkin RV, Sanda S, Harris KM, Nepom GT, Togias A, Durham SR (2021). Differential Induction of Allergen-specific IgA Responses following Timothy Grass Subcutaneous and Sublingual Immunotherapy. J Allergy Clin Immunol, S0091-6749 (21), 00552-2.

Suarez-Farinas M, Suprun M, Bahnson HT, Raghunathan R, Getts R, duToit G, Lack G, Sampson HA. (2021). Evolution of epitope-specific IgE and IgG 4 antibodies in children enrolled in the LEAP trial. The Journal of Allergy and Clinical Immunology, S0091-6749 (21).

http://dx.doi.org/10.1016/j.jaci.2021.01.030

PMID: 

33592205

PMCID: 

PMC8480440

Halken S, Muraro A, de Silva D, Khaleva E, Angier E, Arasi S, Arshad H, Bahnson HT, Beyer K, Boyle R, Du Toit G, Ebisawa M, Eigenmann P, Grimshaw K, Hoest A, Jones C, Lack G, Nadeau K, O'Mahony L, Szajewska H, Venter C, Verhasselt V, Wong GWK, Roberts G (2021). EAACI guideline: Preventing the development of food allergy in infants and young children. Pediatric Allergy and Immunology, Online ahead of print.

http://dx.doi.org/DOI:10.1111/pai.13496

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33710678

PMCID: 

Suarez-Farinas M, Suprun M, Kearney P, Getts R, Grishina G, Hayward C, Luta D, Porter A, Witmer M, Du Toit G, Lack G, Chinthrajah RS, Galli SJ, Nadeau K, Sampson H (2021). Accurate and reproducible diagnosis of peanut allergy using epitope mapping. Allergy, 76 (12), 3789-3797.

http://dx.doi.org/10.1111/all.14905

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33991353

PMCID: 

PMC8607840

Irizar H, Kanchan K, Mathias RA, Bunyavanich S. (2021). Advancing Food Allergy Through Omics Sciences. J Allergy Clin Immunol, 9 (1), 119-129.

http://dx.doi.org/10.1016/j.jaip.2020.07.044

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PMC7855623

Kanchan K, Clay S, Irizar H, Bunyavanich S, Mathias RA (2021). Current insights into the genetics of food allergy. J Allergy Clin Immunol, 147 (1), 15-28.

http://dx.doi.org/10.1016%2Fj.jaci.2020.10.039

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33436162

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PMC8261836

McKinney EF, Cuthbertson I, Harris KM, Smilek D, Connor C, Manferrari G, Carr EJ, Zamvil SS, Smith KGC (2021). A CD8 + NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis. Nat Commun, 12 (1), 635.

http://dx.doi.org/10.1038/s41467-020-20594-2

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33504809

PMCID: 

PMC7840761

Harris KM, Smilek DE, Byron M, Lim N, Barry WT, McNamara J, Garcet S, Konrad RJ, Stengelin M, Bathala P, Korman NJ, Feldman SR, Boh EE, Barber K, Laumann AE, Helfrich YR, Krueger GG, Sofen H, Bissonnette R, Krueger JG (2021). Effect of Costimulatory Blockade With Abatacept After Ustekinumab Withdrawal in Patients With Moderate to Severe Plaque Psoriasis: The PAUSE Randomized Clinical Trial. JAMA Dermatol., 157 (11), 1306-1315.

http://dx.doi.org/10.1001/jamadermatol.2021.3492

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34643650

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PMC8515260

Berti A, Hillion S, Hummel AM, Son YM, Chriti N, Peikert T, Carmona EM, Abdulahad WH, Heeringa P, Harris KM, St Clair EW, Brunetta P, Fervenza F, Langford C, Kallenberg C, Merkel P, Monach PA, Seo P, Spiera RF, Stone JH, Grandi G, Sun J, Pers JO, Specks U, Cornec D (2021). Circulating autoreactive proteinase 3 + B cells and tolerance checkpoints in ANCA-associated vasculitis. JCI Insight, 6 (22), e150999.

http://dx.doi.org/10.1172/jci.insight.150999

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34618687

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PMC8663783

Shaked O, Demetris J, Levitsky J, Feng S, Loza BL, Punch J, Reyes J, Klintmalm G, Jackson W, DesMarais M, Sayre P, Shaked A, Reddy KR (2021). Impact of Donor and Recipient Clinical Characteristics and Hepatic Histology on Steatosis/Fibrosis Following Liver Transplantation. Transplantation, Online ahead of print.

Tanimine N, Burrell BE, Deng K, Rickert C, Lee KM, Feeney N, Pardo J, LeGuern C, Markmann JF (2021). Detection of alloreactive T cells from cryopreserved human peripheral blood mononuclear cells. J Immunol Methods, 491 (112987).

Obradovic A, Shen Y, Sykes M, Fu J. (2021). Integrated Analysis Toolset for Defining and Tracking Alloreactive T-cell Clones After Human Solid Organ and Hematopoietic Stem Cell Transplantation. Software Impacts, 10, 100142.

http://dx.doi.org/10.1016/j.simpa.2021.100142

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35291378

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PMC8920412

Fu J, Khosravi-Maharlooei M, Sykes M (2021). High Throughput Human T Cell Receptor Sequencing: A New Window Into Repertoire Establishment and Alloreactivity. Front Immunol, 12.

http://dx.doi.org/10.3389/fimmu.2021.777756

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34804070

PMCID: 

PMC8604183

Song S, Manook M, Kwun J, Jackson AM, Knechtle SJ, Kelsoe G. (2021). Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells. Front Immunol, 12 (705140).

http://dx.doi.org/10.3389/fimmu.2021.705140

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34326847

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PMC8313870

Diggins KE, Serti E, Muir VS, Rosasco M, Lu T, Balmas E, Nepom GT, Linsley PS (2021). Exhausted-like CD8 T cell phenotypes linked to C-peptide preservation in alefacept-treated T1D subjects. JCI Insight, 6 (3), 142680.

http://dx.doi.org/10.1172/jci.insight.142680

PMID: 

33351781

PMCID: 

PMC7934874

Sims EK, Bundy BN, Stier K, Serti E, Lim N, Long SA, Geyer SM, Moran A, Greenbaum CJ, Evans-Molina C, Herold KC; Type 1 Diabetes TrialNet Study Group. (2021). Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals. Sci Transl Med., 13 (583).

Linsley PS, Barahmand-Pour-Whitman F, Balmas E, DeBerg HA, Flynn KJ, Hu AK, Rosasco M, Chen J, O'Rourke C, Serti E, Gersuk VH, Motwani K, Seay HR, Brusko TM, Kwok WW, Speake C, Greenbaum CJ, Nepom GT, Cerosaletti K (2021). Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes. JCI Insight, 6 (22), e151349.

http://dx.doi.org/10.1172/jci.insight.151349

PMID: 

34806648

PMCID: 

PMC8663791

Greenbaum CJ, Serti E, Lambert K, Weiner LJ, Kanaparthi S, Lord S, Gitelman SE, Wilson DM, Gaglia JL, Griffin KJ, Russell WE, Raskin P, Moran A, Steven M. Willi, Tsalikian E, DiMeglio LA, Herold KC, Moore WV, Goland R, Harris M, Craig ME, Schatz DA, Baidal DA, Rodriguez H, Utzschneider KM, Nel HJ, Soppe CL, Boyle KD, Cerosaletti K, Keyes-Elstein L, Long SA, Thomas R, McNamara JG, Buckner JH, Sanda S, ITN058AI EXTEND Study Team (2021). IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes. JCI Insight, 6 (21), e150074.

http://dx.doi.org/10.1172/jci.insight.150074

PMID: 

34747368

PMCID: 

PMC8663550

Diggins KE, Serti E, Muir V, Rosasco M, Lu T, Balmas E, Nepom G, Long SA, Linsley P (2021). Exhausted CD8+ T Cells linked to Alefacept response in T1D have distinct trajectories differing by KIR phenotype. JCI Insight, e142680.

http://dx.doi.org/10.1172/jci.insight.142680

PMID: 

33351781

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Review & Commentary

Baloh C, Mathias R (2023). Recent progress in the genetic and epigenetic underpinnings of atopy. Journal of Allergy and Clinical Immunology, 151 (1), 60-69.

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