Articles

Anwar IJ, Li S, Mulvihill M, Schmitz R, Shaw B, Gao Q, Swan-Nesbit S, Cheatham LA, How T, Miller A, Williams K, Yin FF, Giles W, Kurtzberg J, Chandran S, Bridges N, Lyakh L, Breeden C, Gandhi K, Sever M, Song M, He X, Kirk AD (2025). Donor-specific mesenchymal stem cell infusion in human and nonhuman primate kidney transplantation. Am J Transplant. https://doi.org/10.1016/j.ajt.2025.05.008 PMID: 40368061.

SoRelle ED, Haukenfrers E, Horn GQ, Jain V, Giarraputo J, Abramson K, Hocke E, Cooney LA, Harris KM, Zamvil SS, Gregory SG, Luftig MA (2025). Early multiple sclerosis activity associated with TBX21+CD21loCXCR3+ B cell expansion resembling EBV-induced phenotypes. JCI Insight, 10(12). https://doi.org/10.1172/jci.insight.188543 PMID: 40359016. PMCID: PMC12220969.

McCluskey D, Shipa MRA, Chowdhury K, James JA, Cooney LA, Ehrenstein MR (2025). IgA2(+) B cells and IgA2 anti-dsDNA antibodies are selectively targeted by belimumab after rituximab therapy in systemic lupus erythematosus. Cell Rep Med, 102247. https://doi.org/10.1016/j.xcrm.2025.102247 PMID: 40706590.

Wan M, Simonin EM, Johnson MM, Zhang X, Lin X, Gao P, Patel CJ, Yousuf A, Snyder MP, Hong X, Wang X, Sampath V, Nadeau KC (2025). Exposomics: a review of methodologies, applications, and future directions in molecular medicine. EMBO Mol Med, 17(4), 599-608. https://doi.org/10.1038/s44321-025-00191-w PMID: 39870881. PMCID: PMC11982546.

Özçam M, Lin DL, Gupta CL, Li A, Gomez JC, Wheatley LM, Baloh CH, Sanda S, Jones SM, Lynch SV (2025). Gut microbial bile and amino acid metabolism associate with peanut oral immunotherapy failure. Nat Commun, 16(1), 6330. https://doi.org/10.1038/s41467-025-61161-x PMID: 40634275. PMCID: PMC12241578.

Lledó-Delgado A, Preston-Hurlburt P, Higdon L, Hu A, James E, Lim N, Long SA, McNamara J, Nguyen H, Serti E, Sumida TS, Herold KC (2025). Latent EBV enhances the efficacy of anti-CD3 mAb in Type 1 diabetes. Nat Commun, 16(1), 5033. https://doi.org/10.1038/s41467-025-60276-5 PMID: 40447640. PMCID: PMC12125364.

Bernstein JS, Vu T, Baloh CH, Huffaker MF, Du Toit G, Dreskin SC (2025). Skin testing improves predictive value of midrange peanut-specific IgE and Ara h 2 levels in the LEAP study. J Allergy Clin Immunol Pract, 13(6), 1478-1480.e2. https://doi.org/10.1016/j.jaip.2025.02.041 PMID: 40081760. PMCID: PMC12278761.

Vionnet J, Torres-Yaguana J, Miquel R, Abraldes JG, Wall J, Kodela E, Lozano JJ, Ruiz P, Navasa M, Marshall A, Nevens F, Gelson W, Leithead J, Masson S, Jaeckel E, Taubert R, Tachtatzis P, Eurich D, Simpson KJ, Bonaccorsi-Riani E, Ferguson J, Quaglia A, Demetris AJ, Lesniak AJ, Elstad M, Delord M, Douiri A, Rebollo-Mesa I, Martinez-Llordella M, Silva JAF, Markmann JF, Sánchez-Fueyo A (2025). Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression. Am J Transplant, 25(5), 1045-1058. https://doi.org/10.1016/j.ajt.2024.12.002 PMID: 39706366.

Higdon LE, Cooney LA, Serti E, Suwannasaen D, Muir VS, Wiedeman AE, Harris KM, Pardo J, Anderson MS, Speake C, Nepom GT, Linsley PS, Sanda S, Long SA (2025). Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes. J Immunol, 214(1), 12-22. https://doi.org/10.1093/jimmun/vkae014 PMID: 40073269. PMCID: PMC11844141.

van Dooren HJ, van Schaik M, Dorjée AL, Arends EJ, Mackay M, Cooney L, Fox DA, Wofsy D, Smilek D, Aranow C, Dall'Era M, Huizinga TWJ, van Kooten C, Toes REM, Diamond B, Teng YKO, Suurmond J (2025). Differences in Dynamics of Specific Antinuclear Antibodies and Their Susceptibility to B Cell-Targeting Treatment in Patients With Systemic Lupus Erythematosus. Arthritis Rheumatol. https://doi.org/10.1002/art.43219 PMID: 40356198.

Aktas ON, Mateja A, Li MJ, Chatman L, Grieco MC, Baloh CH, Huffaker M, Wheatley LM, du Toit G, Lack G, Brittain E, Frischmeyer-Guerrerio PA (2025). Evaluation of Intestinal Permeability Using Serum Biomarkers in Learning Early About Peanut Allergy Trial. Allergy. https://doi.org/10.1111/all.16464 PMID: 39803811. PMCID: PMC12255823.

Tanimine N, Markmann JF, Wood-Trageser MA, Demetris AJ, Mason K, Silva JAF, Levitsky J, Feng S, Humar A, Emond JC, Shaked A, Klintmalm G, Sanchez-Fueyo A, Lesniak D, Breeden CP, Nepom GT, Bridges ND, Goldstein J, Larsen CP, DesMarais M, Gaile G, Chandran S (2025). Donor-specific immune senescence as a candidate biomarker of operational tolerance following liver transplantation in adults: Results of a prospective, multicenter cohort study. Am J Transplant, 25(5), 1030-1044. https://doi.org/10.1016/j.ajt.2024.10.022 PMID: 39505152.

Chandran S, Vincenti F (2025). Antiplasma cell antibodies: A new era of human leukocyte antigen antibody control in solid organ transplantation. Am J Transplant, 25(1), 19-26. https://doi.org/10.1016/j.ajt.2024.10.005 PMID: 39384021.

Ajmal N, Bogart MC, Khan P, Max-Harry IM, Healy AM, Nunemaker CS (2024). Identifying Promising Immunomodulators for Type 1 Diabetes (T1D) and Islet Transplantation. J Diabetes Res, 2024, 5151171. https://doi.org/10.1155/jdr/5151171 PMID: 39735417. PMCID: PMC11679277.

Konyana SPP, Teixeira NF, Pirjol L, Thwala B, Nkoyane W, Porter M, Gxolo F, Phillips E, Lehloenya R, Mankahla A, Peter J (2024). Spectrum of offending drugs and cutaneous adverse drug reactions requiring hospitalisation in a tertiary South African hospital in TB/HIV endemic setting. Front Allergy, 5, 1481281. https://doi.org/10.3389/falgy.2024.1481281 PMID: 39668949. PMCID: PMC11634803.

Anchordoquy T, Artzi N, Balyasnikova IV, Barenholz Y, La-Beck NM, Brenner JS, Chan WCW, Decuzzi P, Exner AA, Gabizon A, Godin B, Lai SK, Lammers T, Mitchell MJ, Moghimi SM, Muzykantov VR, Peer D, Nguyen J, Popovtzer R, Ricco M, Serkova NJ, Singh R, Schroeder A, Schwendeman AA, Straehla JP, Teesalu T, Tilden S, Simberg D (2024). Mechanisms and Barriers in Nanomedicine: Progress in the Field and Future Directions. ACS Nano, 18(22), 13983-13999. https://doi.org/10.1021/acsnano.4c00182 PMID: 38767983. PMCID: PMC11214758.

Porter M, Smith R, Teixeira N, Thwala B, Choshi P, Phillips EJ, Meintjes G, Dlamini S, Peter JG, Lehloenya RJ (2024). First-Line Antituberculosis Drug Challenge Reactions in Drug Reaction With Eosinophilia and Systemic Symptoms Syndrome in an HIV Endemic Setting. J Allergy Clin Immunol Pract, 12(10), 2798-2808.e12. https://doi.org/10.1016/j.jaip.2024.05.045 PMID: 38852619. PMCID: PMC11832015.

Khalid MB, Zektser E, Chu E, Li M, Utoh J, Ryan P, Loving HS, Harb R, Kattappuram R, Chatman L, Hartono S, Claudio-Etienne E, Sun G, Feener EP, Li Z, Lai SK, Le Q, Schwartz LB, Lyons JJ, Komarow H, Zhou ZH, Raza H, Pao M, Laky K, Holland SM, Brittain E, Frischmeyer-Guerrerio PA (2024). A randomized double-blinded trial to assess recurrence of systemic allergic reactions following COVID-19 mRNA vaccination. J Allergy Clin Immunol, 153(6), 1634-1646. https://doi.org/10.1016/j.jaci.2024.03.001 PMID: 38460680. PMCID: PMC11162316.

Li Z, Ma A, Miller I, Starnes R, Talkington A, Stone CA, Phillips EJ, Choudhary SK, Commins SP, Lai SK (2024). Development of anti-PEG IgG/IgM/IgE ELISA assays for profiling anti-PEG immunoglobulin response in PEG-sensitized individuals and patients with alpha-gal allergy. J Control Release, 366, 342-348. https://doi.org/10.1016/j.jconrel.2024.01.003 PMID: 38182056. PMCID: PMC11182197.

Asif BA, Koh C, Phillips EJ, Gu J, Li YJ, Barnhart H, Chalasani N, Fontana RJ, Hayashi PH, Navarro VJ, Hoofnagle JH, Drug Induced Liver Injury Network (DILIN) (2024). Vancomycin-Induced Liver Injury, DRESS, and HLA-A∗32:01. J Allergy Clin Immunol Pract, 12(1), 168-174.e2. https://doi.org/10.1016/j.jaip.2023.09.011 PMID: 37739311. PMCID: PMC10885131.

Baloh CH, Lim N, Huffaker M, Patel P, Tversky J, Du Toit G, Lack G, Laidlaw TM, MacGlashan DW (2024). Peanut-specific IgG subclasses as biomarkers of peanut allergy in LEAP study participants. World Allergy Organ J, 17(8), 100940. https://doi.org/10.1016/j.waojou.2024.100940 PMID: 39247520. PMCID: PMC11380385.

Özçam M, Lin DL, Gupta CL, Li A, Wheatley LM, Baloh CH, Sanda S, Jones SM, Lynch SV (2024). Enhanced Gut Microbiome Capacity for Amino Acid Metabolism is associated with Peanut Oral Immunotherapy Failure. medRxiv. https://doi.org/10.1101/2024.07.15.24309840 PMID: 39072014. PMCID: PMC11275660.

Greenbaum CJ, Nepom GT, Wood-Heickman LK, Wherrett DK, DiMeglio LA, Herold KC, Krischer JP (2024). Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop. Diabetes, 73(11), 1780-1790. https://doi.org/10.2337/dbi24-0020 PMID: 39167668. PMCID: PMC11493760.

Witkop EM, Diggins K, Wiedeman A, Serti E, Nepom G, Gersuk VH, Fuchs B, Long SA, Linsley PS (2024). Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8(+) T cells beneficial in type 1 diabetes. Commun Biol, 7(1), 773. https://doi.org/10.1038/s42003-024-06456-3 PMID: 38937521. PMCID: PMC11211332.

Foong RX, Du Toit G, van Ree R, Bahnson HT, Radulovic S, Craven J, Kwok M, Jama Z, Versteeg SA, Brough HA, Logan K, Perkin MR, Flohr C, Lack G, Santos AF (2024). Biomarkers of peanut allergy in children over time. Allergy, 79(10), 2775-2786. https://doi.org/10.1111/all.16193 PMID: 38887787. PMCID: PMC11875691.

Linsley PS, Nakayama M, Balmas E, Chen J, Barahmand-Pour-Whitman F, Bansal S, Bottorff T, Serti E, Speake C, Pugliese A, Cerosaletti K (2024). Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. Nat Commun, 15(1), 4971. https://doi.org/10.1038/s41467-024-48833-w PMID: 38871688. PMCID: PMC11176301.

Bender C, Wiedeman AE, Hu A, Ylescupidez A, Sietsema WK, Herold KC, Griffin KJ, Gitelman SE, Long SA, T-Rex Study Group†, T-Rex Clinical Study Group (2024). A phase 2 randomized trial with autologous polyclonal expanded regulatory T cells in children with new-onset type 1 diabetes. Sci Transl Med, 16(746), eadn2404. https://doi.org/10.1126/scitranslmed.adn2404 PMID: 38718135.

Chen CC, Buchheit KM, Lee PY, Brodeur KE, Sohail A, Cho L, Baloh CH, Balestrieri B, Derakhshan T, Feng C, Boyce JA, Dwyer DF, Laidlaw TM (2024). IL-4Rα signaling promotes barrier-altering oncostatin M and IL-6 production in aspirin-exacerbated respiratory disease. J Allergy Clin Immunol, 154(2), 458-467.e3. https://doi.org/10.1016/j.jaci.2024.04.020 PMID: 38704098. PMCID: PMC11305950.

Higdon LE, Scheiding S, Kus AM, Lim N, Long SA, Anderson MS, Wiedeman AE (2024). Impact on in-depth immunophenotyping of delay to peripheral blood processing. Clin Exp Immunol, 217(2), 119-132. https://doi.org/10.1093/cei/uxae041 PMID: 38693758. PMCID: PMC11239563.

Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF (2024). Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue. Nat Commun, 15(1), 1564. https://doi.org/10.1038/s41467-024-45012-9 PMID: 38378682. PMCID: PMC10879116.

Wiley LK, Shortt JA, Roberts ER, Lowery J, Kudron E, Lin M, Mayer D, Wilson M, Brunetti TM, Chavan S, Phang TL, Pozdeyev N, Lesny J, Wicks SJ, Moore ET, Morgenstern JL, Roff AN, Shalowitz EL, Stewart A, Williams C, Edelmann MN, Hull M, Patton JT, Axell L, Ku L, Lee YM, Jirikowic J, Tanaka A, Todd E, White S, Peterson B, Hearst E, Zane R, Greene CS, Mathias R, Coors M, Taylor M, Ghosh D, Kahn MG, Brooks IM, Aquilante CL, Kao D, Rafaels N, Crooks KR, Hess S, Barnes KC, Gignoux CR (2024). Building a vertically integrated genomic learning health system: The biobank at the Colorado Center for Personalized Medicine. Am J Hum Genet, 111(1), 11-23. https://doi.org/10.1016/j.ajhg.2023.12.001 PMID: 38181729. PMCID: PMC10806731.

Markmann JF, Burrell BE, Bromberg JS, Hartono C, Kaufman DB, Possselt AM, Naji A, Bridges ND, Breeden C, Kanaparthi S, Pardo J, Kopetskie H, Mason K, Lim N, Chandran S (2024). Immunosuppression withdrawal in living-donor renal transplant recipients following induction with antithymocyte globulin and rituximab: Results of a prospective clinical trial. Am J Transplant, 24(7), 1193-1204. https://doi.org/10.1016/j.ajt.2024.03.007 PMID: 38467375.

Du Toit G, Huffaker MF, Radulovic S, Feeney M, Fisher HR, Byron M, Dunaway L, Calatroni A, Johnson M, Foong RX, Marques-Mejias A, Bartha I, Basting M, Brough HA, Baloh C, Laidlaw TM, Bahnson HT, Roberts G, Plaut M, Wheatley LM, Lack G, Immune Tolerance Network LEAP-Trio Trial Team (2024). Follow-up to Adolescence after Early Peanut Introduction for Allergy Prevention. NEJM Evid, 3(6), EVIDoa2300311. https://doi.org/10.1056/EVIDoa2300311 PMID: 38804779.

Mathieu C, Wiedeman A, Cerosaletti K, Long SA, Serti E, Cooney L, Vermeiren J, Caluwaerts S, Van Huynegem K, Steidler L, Blomme S, Rottiers P, Nepom GT, Herold KC, AG019-T1D-101 Trial Investigators (2024). A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab. Diabetologia, 67(1), 27-41. https://doi.org/10.1007/s00125-023-06014-2 PMID: 37782353. PMCID: PMC10709251.

Keet C, Sicherer SH, Bunyavanich S, Visness C, Fulkerson PC, Togias A, Davidson W, Perry S, Hamrah S, Calatroni A, Robinson K, Dunaway L, Davis CM, Anvari S, Leong-Kee SM, Hershey GK, DeFranco E, Devonshire A, Kim H, Joseph C, Davidson B, Strong NK, Tsuang AJ, Groetch M, Wang J, Dantzer J, Mudd K, Aina A, Shreffler W, Yuan Q, Simmons V, Leung DYM, Hui-Beckman J, Ramos JA, Chinthrajah S, Winn V, Sindher T, Jones SM, Manning NA, Scurlock AM, Kim E, Stuebe A, Gern JE, Singh AM, Krupp J, Wood RA (2023). The SunBEAm birth cohort: Protocol design. J Allergy Clin Immunol Glob, 2(3). https://doi.org/10.1016/j.jacig.2023.100124 PMID: 37771674. PMCID: PMC10509956.

Mariottini A, De Matteis E, Cencioni MT, Muraro PA (2023). Haematopoietic Stem Cell Transplantation for the Treatment of Multiple Sclerosis: Recent Advances. Curr Neurol Neurosci Rep, 23(9), 507-520. https://doi.org/10.1007/s11910-023-01290-2 PMID: 37589918. PMCID: PMC10468923.

Shen Z, Robert L, Stolpman M, Che Y, Walsh A, Saffery R, Allen KJ, Eckert J, Young A, Deming C, Chen Q, Conlan S, Laky K, Li JM, Chatman L, Saheb Kashaf S, NISC Comparative Sequencing Program, VITALITY team, Kong HH, Frischmeyer-Guerrerio PA, Perrett KP, Segre JA (2023). A genome catalog of the early-life human skin microbiome. bioRxiv. https://doi.org/10.1101/2023.05.22.541509 PMID: 37398010. PMCID: PMC10312837.

Frezza D, DiCarlo E, Hale C, Ramirez D, Mehta B, Slater D, Habib S, Frank MO, Spolaore E, Smith MH, Donlin L, Goodman S, Thompson JR, Orange DE (2023). Computer Vision Analysis of Rheumatoid Arthritis Synovium Reveals Lymphocytic Inflammation Is Associated With Immunoglobulin Skewing in Blood. Arthritis Rheumatol, 75(12), 2137-2147. https://doi.org/10.1002/art.42653 PMID: 37463182. PMCID: PMC10794535.

Mabrey FL, Nian H, Yu C, Barnes EM, Malhotra U, Mikacenic C, Goldstein J, O'Mahony DS, Garcia-Diaz J, Finn P, Voelker K, Morrell ED, Self WH, Becker PM, Martin TR, Wurfel MM (2023). Phase 2, randomized, double-blind, placebo-controlled multi-center trial of the clinical and biological effects of anti-CD14 treatment in hospitalized patients with COVID-19 pneumonia. EBioMedicine, 93, 104667. https://doi.org/10.1016/j.ebiom.2023.104667 PMID: 37336058. PMCID: PMC10276526.

Greenhawt M, Dribin TE, Abrams EM, Shaker M, Chu DK, Golden DBK, Akin C, Anagnostou A, ALMuhizi F, Alqurashi W, Arkwright P, Baldwin JL, Banerji A, Bégin P, Ben-Shoshan M, Bernstein J, Bingemann TA, Bindslev-Jensen C, Blumenthal K, Byrne A, Cahill J, Cameron S, Campbell D, Campbell R, Cavender M, Chan ES, Chinthrajah S, Comberiati P, Eastman JJ, Ellis AK, Fleischer DM, Fox A, Frischmeyer-Guerrerio PA, Gagnon R, Garvey LH, Grayson MH, Isabwe GAC, Hartog N, Hendron D, Horner CC, Hourihane JO, Iglesia E, Kan M, Kaplan B, Katelaris CH, Kim H, Kelso JM, Khan DA, Lang D, Ledford D, Levin M, Lieberman JA, Loh R, Mack DP, Mazer B, Mody K, Mosnaim G, Munblit D, Mustafa SS, Nanda A, Nathan R, Oppenheimer J, Otani IM, Park M, Pawankar R, Perrett KP, Peter J, Phillips EJ, Picard M, Pitlick M, Ramsey A, Rasmussen TH, Rathkopf MM, Reddy H, Robertson K, Rodriguez Del Rio P, Sample S, Sheshadri A, Sheik J, Sindher SB, Spergel JM, Stone CA, Stukus D, Tang MLK, Tracy JM, Turner PJ, Vander Leek TK, Wallace DV, Wang J, Wasserman S, Weldon D, Wolfson AR, Worm M, Yacoub MR (2023). Updated guidance regarding the risk of allergic reactions to COVID-19 vaccines and recommended evaluation and management: A GRADE assessment and international consensus approach. J Allergy Clin Immunol, 152(2), 309-325. https://doi.org/10.1016/j.jaci.2023.05.019 PMID: 37295474. PMCID: PMC10247143.

Veenstra S, Porter MN, Thwala BN, Pillay N, Panieri MA, van der Westhuizen J, Phillips EJ, Meintjes G, Dlamini S, Lehloenya RJ, Peter J (2023). Long-term HIV and tuberculosis outcomes in patients hospitalised with severe cutaneous adverse reactions. J Clin Tuberc Other Mycobact Dis, 32, 100374. https://doi.org/10.1016/j.jctube.2023.100374 PMID: 37214159. PMCID: PMC10196841.

Casal Moura M, Deng Z, Brooks SR, Tew W, Fervenza FC, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Stone JH, Prunotto M, Grayson PC, Specks U (2023). Risk of relapse of ANCA-associated vasculitis among patients homozygous for the proteinase 3 gene Val119Ile polymorphism. RMD Open, 9(1). https://doi.org/10.1136/rmdopen-2022-002935 PMID: 36990659. PMCID: PMC10069578.

Chimbetete T, Buck C, Choshi P, Selim R, Pedretti S, Divito SJ, Phillips EJ, Lehloenya R, Peter J (2023). HIV-Associated Immune Dysregulation in the Skin: A Crucible for Exaggerated Inflammation and Hypersensitivity. J Invest Dermatol, 143(3), 362-373. https://doi.org/10.1016/j.jid.2022.07.035 PMID: 36549954. PMCID: PMC9974923.

Gibson A, Deshpande P, Campbell CN, Krantz MS, Mukherjee E, Mockenhaupt M, Pirmohamed M, Palubinsky AM, Phillips EJ (2023). Updates on the immunopathology and genomics of severe cutaneous adverse drug reactions. J Allergy Clin Immunol, 151(2), 289-300.e4. https://doi.org/10.1016/j.jaci.2022.12.005 PMID: 36740326. PMCID: PMC9976545.

Broglie L, Friend BD, Chhabra S, Logan BR, Bupp C, Schiller G, Savani BN, Stadtmauer E, Abraham AA, Aljurf M, Badawy SM, Perez MAD, Guinan EC, Hashem H, Krem MM, Lazarus HM, Rotz SJ, Wirk B, Yared JA, Pasquini M, Thakar MS, Sorror ML (2023). Expanded HCT-CI Definitions Capture Comorbidity Better for Younger Patients of Allogeneic HCT for Nonmalignant Diseases. Transplant Cell Ther, 29(2), 125.e1-125.e9. https://doi.org/10.1016/j.jtct.2022.11.020 PMID: 36442768. PMCID: PMC9911359.

Stone CA Jr, Robinson LB, Li L, Krantz MS, Kwah JH, Ortega G, Mancini C, Wolfson AR, Saff RR, Samarakoon U, Hong DI, Koo G, Chow TG, Gruchalla R, Liao JX, Kuster JK, Price C, Ahola C, Khan DA, Phillips EJ, Banerji A, Blumenthal KG (2023). Clinical Phenotypes of Immediate First-Dose Reactions to mRNA COVID-19: A Multicenter Latent Class Analysis. J Allergy Clin Immunol Pract, 11(2), 458-465.e1. https://doi.org/10.1016/j.jaip.2022.08.048 PMID: 36108922. PMCID: PMC9468049.

Macy E, Trautmann A, Chiriac AM, Demoly P, Phillips EJ (2023). Advances in the Understanding of Drug Hypersensitivity: 2012 Through 2022. J Allergy Clin Immunol Pract, 11(1), 80-91. https://doi.org/10.1016/j.jaip.2022.10.025 PMID: 36384652.

Stollings JL, Koo G, Lindsell CJ, Dear ML, McCoy A, Rice TW, Phillips EJ, Stone CA Jr, Vanderbilt Learning Healthcare System Investigators (2023). Risk-stratified management to remove low-risk penicillin allergy labels in the patients with COVID-19 in the intensive care unit. J Allergy Clin Immunol Pract, 11(2), 632-635. https://doi.org/10.1016/j.jaip.2022.08.043 PMID: 36100133. PMCID: PMC9464306.

Xiao Q, Mears J, Nathan A, Ishigaki K, Baglaenko Y, Lim N, Cooney LA, Harris KM, Anderson MS, Fox DA, Smilek DE, Krueger JG, Raychaudhuri S (2023). Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin. Nat Commun, 14(1), 6268. https://doi.org/10.1038/s41467-023-41984-2 PMID: 37805522. PMCID: PMC10560299.

Huffaker MF, Kanchan K, Bahnson HT, Ruczinski I, Shankar G, Leung DYM, Baloh C, Du Toit G, Lack G, Nepom GT, Mathias RA (2023). Epidermal differentiation complex genetic variation in atopic dermatitis and peanut allergy. J Allergy Clin Immunol, 151(4), 1137-1142.e4. https://doi.org/10.1016/j.jaci.2022.11.008 PMID: 36403663.

Shen Z, Robert L, Stolpman M, Che Y, Allen KJ, Saffery R, Walsh A, Young A, Eckert J, Deming C, Chen Q, Conlan S, Laky K, Li JM, Chatman L, Kashaf SS, NISC Comparative Sequencing Program, VITALITY team, Kong HH, Frischmeyer-Guerrerio PA, Perrett KP, Segre JA (2023). A genome catalog of the early-life human skin microbiome. Genome Biol, 24(1), 252. https://doi.org/10.1186/s13059-023-03090-w PMID: 37946302. PMCID: PMC10636849.

Azzouz DF, Chen Z, Izmirly PM, Chen LA, Li Z, Zhang C, Mieles D, Trujillo K, Heguy A, Pironti A, Putzel GG, Schwudke D, Fenyo D, Buyon JP, Alekseyenko AV, Gisch N, Silverman GJ (2023). Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares. Ann Rheum Dis, 82(10), 1315-1327. https://doi.org/10.1136/ard-2023-223929 PMID: 37365013. PMCID: PMC10511964.

Ylescupidez A, Bahnson HT, O'Rourke C, Lord S, Speake C, Greenbaum CJ (2023). A standardized metric to enhance clinical trial design and outcome interpretation in type 1 diabetes. Nat Commun, 14(1), 7214. https://doi.org/10.1038/s41467-023-42581-z PMID: 37940642. PMCID: PMC10632453.

Taylor PN, Collins KS, Lam A, Karpen SR, Greeno B, Walker F, Lozano A, Atabakhsh E, Ahmed ST, Marinac M, Latres E, Senior PA, Rigby M, Gottlieb PA, Dayan CM, Trial Outcome Markers Initiative collaboration (2023). C-peptide and metabolic outcomes in trials of disease modifying therapy in new-onset type 1 diabetes: an individual participant meta-analysis. Lancet Diabetes Endocrinol, 11(12), 915-925. https://doi.org/10.1016/S2213-8587(23)00267-X PMID: 37931637.

Cochran W, Salto-Alejandre S, Barker L, Langlee J, Freed K, Carter D, Bannon J, Goddard D, Mostafa H, Werbel W, Shah P, Segev D, Brennan D, Avery R (2023). COVID-19 Outcomes in Solid Organ Transplant Recipients Who Received Tixagevimab-cilgavimab Prophylaxis and/or Bebtelovimab Treatment in a Nurse-driven Monoclonal Antibody Program During the Omicron Surge. Transplantation, 107(2), e60-e61. https://doi.org/10.1097/TP.0000000000004418 PMID: 36228295. PMCID: PMC9875834.

Delgado AL, Preston-Hurlburt P, Lim N, Sumida TS, Long SA, McNamara J, Serti E, Higdon L, Herold KC (2023). Latent EBV impairs immune cell signaling and enhances the efficacy of anti-CD3 mAb in Type 1 Diabetes. medRxiv. https://doi.org/10.1101/2023.07.11.23292344 PMID: 37502867. PMCID: PMC10370230.

Calise J, DeBerg H, Garabatos N, Khosa S, Bajzik V, Calderon LB, Aldridge K, Rosasco M, Ferslew BC, Zhu T, Smulders R, Wheatley LM, Laidlaw TM, Qin T, Chichili GR, Adelman DC, Farrington M, Robinson D, Jeong D, Jones SM, Sanda S, Larson D, Kwok WW, Baloh C, Nepom GT, Wambre E, IMPACT (2023). Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy. J Allergy Clin Immunol, 152(1), 155-166.e9. https://doi.org/10.1016/j.jaci.2023.03.020 PMID: 37003475. PMCID: PMC10330178.

Linsley P, Nakayama M, Balmas E, Chen J, Pour F, Bansal S, Serti E, Speake C, Pugliese A, Cerosaletti K (2023). Self-reactive germline-like TCR alpha chains shared between blood and pancreas. Res Sq. https://doi.org/10.21203/rs.3.rs-3446917/v1 PMID: 37886513. PMCID: PMC10602137.

Narsale A, Almanza F, Tran T, Lam B, Seo D, Vu A, Long SA, Cooney L, Serti E, Davies JD (2023). Th2 cell clonal expansion at diagnosis in human type 1 diabetes. Clin Immunol, 257, 109829. https://doi.org/10.1016/j.clim.2023.109829 PMID: 37907122.

Balmas E, Chen J, Hu AK, DeBerg HA, Rosasco MG, Gersuk VH, Serti E, Speake C, Greenbaum CJ, Nepom GT, Linsley PS, Cerosaletti K (2023). Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes. JCI Insight, 8(21). https://doi.org/10.1172/jci.insight.167881 PMID: 37751304. PMCID: PMC10721267.

Wood-Trageser MA, Lesniak D, Gambella A, Golnoski K, Feng S, Bucuvalas J, Sanchez-Fueyo A, Demetris AJ (2023). Next-generation pathology detection of T cell-antigen-presenting cell immune synapses in human liver allografts. Hepatology, 77(2), 355-366. https://doi.org/10.1002/hep.32666 PMID: 35819312. PMCID: PMC9834436.

Duan M, Nguyen DC, Joyner CJ, Saney CL, Tipton CM, Andrews J, Lonial S, Kim C, Hentenaar I, Kosters A, Ghosn E, Jackson A, Knechtle S, Maruthamuthu S, Chandran S, Martin T, Rajalingam R, Vincenti F, Breeden C, Sanz I, Gibson G, Lee FE (2023). Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses. Cell Rep, 42(7), 112682. https://doi.org/10.1016/j.celrep.2023.112682 PMID: 37355988. PMCID: PMC10391632.

Sykes M, Chandran S, Kawai T, Levitsky J, Mapara M, Mathew J, Thomson A, Yamada K (2023). Meeting Report: The Fifth International Samuel Strober Workshop on Clinical Immune Tolerance. Transplantation, 107(3), 564-569. https://doi.org/10.1097/TP.0000000000004473 PMID: 36808845.

Gamerith G, Mildner F, Merkel PA, Harris K, Cooney L, Lim N, Spiera R, Seo P, Langford CA, Hoffman GS, St Clair EW, Fervenza FC, Monach P, Ytterberg SR, Geetha D, Amann A, Wolf D, Specks U, Stone JH, Kronbichler A (2023). Association of baseline soluble immune checkpoints with the risk of relapse in PR3-ANCA vasculitis following induction of remission. Ann Rheum Dis, 82(2), 253-261. https://doi.org/10.1136/ard-2022-222479 PMID: 35973802.

Russell WE, Bundy BN, Anderson MS, Cooney LA, Gitelman SE, Goland RS, Gottlieb PA, Greenbaum CJ, Haller MJ, Krischer JP, Libman IM, Linsley PS, Long SA, Lord SM, Moore DJ, Moore WV, Moran AM, Muir AB, Raskin P, Skyler JS, Wentworth JM, Wherrett DK, Wilson DM, Ziegler AG, Herold KC, Type 1 Diabetes TrialNet Study Group (2023). Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial. Diabetes Care, 46(5), 1005-1013. https://doi.org/10.2337/dc22-2200 PMID: 36920087. PMCID: PMC10154649.

Odler B, Riedl R, Gauckler P, Shin JI, Leierer J, Merkel PA, St Clair W, Fervenza F, Geetha D, Monach P, Jayne D, Smith RM, Rosenkranz A, Specks U, Stone JH, Kronbichler A, RAVE−ITN Research Group (2023). Risk factors for serious infections in ANCA-associated vasculitis. Ann Rheum Dis, 82(5), 681-687. https://doi.org/10.1136/ard-2022-223401 PMID: 36702528. PMCID: PMC10176387.

Casal Moura M, Thompson GE, Nelson DR, Fussner LA, Hummel AM, Jenne DE, Emerling D, Fervenza FC, Kallenberg CGM, Langford CA, McCune WJ, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, Stone JH, Robinson WH, Specks U, WGET and RAVE-ITN Research Groups (2023). Activation of a Latent Epitope Causing Differential Binding of Antineutrophil Cytoplasmic Antibodies to Proteinase 3. Arthritis Rheumatol, 75(5), 748-759. https://doi.org/10.1002/art.42418 PMID: 36515151. PMCID: PMC10191989.

Berti A, Hillion S, Konig MF, Moura MC, Hummel AM, Carmona E, Peikert T, Fervenza FC, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, Brunetta P, St Clair EW, Harris KM, Stone JH, Grandi G, Pers JO, Specks U, Cornec D (2023). Autoreactive Plasmablasts After B Cell Depletion With Rituximab and Relapses in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 75(5), 736-747. https://doi.org/10.1002/art.42388 PMID: 36281741. PMCID: PMC10280646.

Grinek S, Suprun M, Raghunathan R, Tomalin LE, Getts R, Bahnson T, Lack G, Sampson HA, Suarez-Farinas M (2023). Epitope-Specific IgE at 1 Year of Age Can Predict Peanut Allergy Status at 5 Years. Int Arch Allergy Immunol, 184(3), 273-278. https://doi.org/10.1159/000526364 PMID: 36502801. PMCID: PMC9991938.

Corren J, Larson D, Altman MC, Segnitz RM, Avila PC, Greenberger PA, Baroody F, Moss MH, Nelson H, Burbank AJ, Hernandez ML, Peden D, Saini S, Tilles S, Hussain I, Whitehouse D, Qin T, Villarreal M, Sever M, Wheatley LM, Nepom GT, Sanda S, Immune Tolerance Network ITN057AD CATNIP Study Team (2023). Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: A randomized controlled trial. J Allergy Clin Immunol, 151(1), 192-201. https://doi.org/10.1016/j.jaci.2022.08.029 PMID: 36223848. PMCID: PMC12205947.

Altman MC, Segnitz RM, Larson D, Jayavelu ND, Smith MT, Patel S, Scadding GW, Qin T, Sanda S, Steveling E, Eifan AO, Penagos M, Jacobson MR, Parkin RV, Shamji MH, Togias A, Durham SR (2023). Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy. J Allergy Clin Immunol, 152(5), 1247-1260. https://doi.org/10.1016/j.jaci.2023.06.025 PMID: 37460024. PMCID: PMC10788383.

Logan K, Bahnson HT, Ylescupidez A, Beyer K, Bellach J, Campbell DE, Craven J, Du Toit G, Clare Mills EN, Perkin MR, Roberts G, van Ree R, Lack G (2023). Early introduction of peanut reduces peanut allergy across risk groups in pooled and causal inference analyses. Allergy, 78(5), 1307-1318. https://doi.org/10.1111/all.15597 PMID: 36435990. PMCID: PMC10202125.

Sever ML, Calatroni A, Roberts G, du Toit G, Bahnson HT, Radulovic S, Larson D, Byron M, Santos AF, Huffaker MF, Wheatley LM, Lack G (2023). Developing a Prediction Model for Determination of Peanut Allergy Status in the Learning Early About Peanut Allergy (LEAP) Studies. J Allergy Clin Immunol Pract, 11(7), 2217-2227.e9. https://doi.org/10.1016/j.jaip.2023.04.032 PMID: 37146884. PMCID: PMC11837399.

Baloh CH, Kanchan K, Shankar G, Nepom GT, Mathias RA, Perry JA (2023). Omics-oriented research illustrated with the LEAP study and the OASIS bioinformatics tool. J Allergy Clin Immunol, 151(2), 416-419. https://doi.org/10.1016/j.jaci.2022.12.003 PMID: 36521801.

Suprun M, Bahnson HT, du Toit G, Lack G, Suarez-Farinas M, Sampson HA (2023). In children with eczema, expansion of epitope-specific IgE is associated with peanut allergy at 5 years of age. Allergy, 78(2), 586-589. https://doi.org/10.1111/all.15572 PMID: 36321870.

Roberts G, Bahnson HT, Du Toit G, O'Rourke C, Sever ML, Brittain E, Plaut M, Lack G (2023). Defining the window of opportunity and target populations to prevent peanut allergy. J Allergy Clin Immunol, 151(5), 1329-1336. https://doi.org/10.1016/j.jaci.2022.09.042 PMID: 36521802. PMCID: PMC10689252.

Kanchan K, Shankar G, Huffaker MF, Bahnson HT, Chinthrajah RS, Sanda S, Manohar M, Ling H, Paschall JE, Toit GD, Ruczinski I, Togias A, Lack G, Nadeau KC, Jones SM, Nepom GT, Mathias RA (2022). HLA-associated outcomes in peanut oral immunotherapy trials identify mechanistic and clinical determinants of therapeutic success. Front Immunol, 13, 941839. https://doi.org/10.3389/fimmu.2022.941839 PMID: 36466872. PMCID: PMC9717393.

Mukherjee EM, Phillips EJ (2022). Where to place etanercept and combination treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis? Ann Allergy Asthma Immunol, 129(3), 269-270. https://doi.org/10.1016/j.anai.2022.06.025 PMID: 35988972. PMCID: PMC9931047.

James F, Goh MSY, Mouhtouris E, Vogrin S, Chua KYL, Holmes NE, Awad A, Copaescu AM, De Luca JF, Zubrinich C, Gin D, Cleland H, Douglas A, Kern JS, Katelaris CH, Thien F, Barnes S, Yun J, Tong W, Smith WB, Carr A, Anderson T, Legg A, Bourke J, Mackay LK, Aung AK, Phillips EJ, Trubiano J (2022). Study protocol: Australasian Registry of Severe Cutaneous Adverse Reactions (AUS-SCAR). BMJ Open, 12(8), e055906. https://doi.org/10.1136/bmjopen-2021-055906 PMID: 35977774. PMCID: PMC9389100.

Gorsline CA, Afghan AK, Stone CA Jr, Phillips EJ, Satyanarayana G (2022). Safety and value of pretransplant antibiotic allergy delabeling in a quaternary transplant center. Transpl Infect Dis, 24(5), e13885. https://doi.org/10.1111/tid.13885 PMID: 35765165. PMCID: PMC9588656.

Zohar T, Atyeo C, Wolf CR, Logue JK, Shuey K, Franko N, Choi RY, Wald A, Koelle DM, Chu HY, Lauffenburger DA, Alter G (2022). A multifaceted high-throughput assay for probing antigen-specific antibody-mediated primary monocyte phagocytosis and downstream functions. J Immunol Methods, 510, 113328. https://doi.org/10.1016/j.jim.2022.113328 PMID: 35934070.

Koo G, Yu R, Phillips EJ, Stone CA Jr (2022). Retrospective stratification of cephalosporin allergy label risk using validated penicillin allergy frameworks. J Allergy Clin Immunol Pract, 10(9), 2472-2475.e1. https://doi.org/10.1016/j.jaip.2022.05.032 PMID: 35690369.

Porter M, Choshi P, Pedretti S, Chimbetete T, Smith R, Meintjes G, Phillips E, Lehloenya R, Peter J (2022). IFN-γ ELISpot in Severe Cutaneous Adverse Reactions to First-Line Antituberculosis Drugs in an HIV Endemic Setting. J Invest Dermatol, 142(11), 2920-2928.e5. https://doi.org/10.1016/j.jid.2022.05.1059 PMID: 35659939. PMCID: PMC9952832.

Corey KB, Koo G, Stone CA Jr, Kroop SF, Fissell WH, Kozlowski S, Zhou ZH, Phillips EJ (2022). A case of coronavirus disease 2019 messenger RNA vaccine tolerance and immune response despite presence of anti-polyethylene glycol antibodies. Ann Allergy Asthma Immunol, 129(2), 246-248. https://doi.org/10.1016/j.anai.2022.05.013 PMID: 35605816. PMCID: PMC9181833.

Banerji A, Norton AE, Blumenthal KG, Stone CA Jr, Phillips E (2022). Rapid progress in our understanding of COVID-19 vaccine allergy: A cause for optimism, not hesitancy. J Allergy Clin Immunol, 150(1), 12-16. https://doi.org/10.1016/j.jaci.2022.03.023 PMID: 35398412. PMCID: PMC8988439.

Copaescu AM, Rosa Duque JS, Phillips EJ (2022). What have we learned about the allergenicity and adverse reactions associated with the severe acute respiratory syndrome coronavirus 2 vaccines: One year later. Ann Allergy Asthma Immunol, 129(1), 40-51. https://doi.org/10.1016/j.anai.2022.03.030 PMID: 35390476. PMCID: PMC8979618.

Sooda A, Rwandamuriye F, Wanjalla CN, Jing L, Koelle DM, Peters B, Leary S, Chopra A, Calderwood MA, Mallal SA, Pavlos R, Watson M, Phillips EJ, Redwood AJ (2022). Abacavir inhibits but does not cause self-reactivity to HLA-B*57:01-restricted EBV specific T cell receptors. Commun Biol, 5(1), 133. https://doi.org/10.1038/s42003-022-03058-9 PMID: 35173258. PMCID: PMC8850454.

Hama N, Abe R, Gibson A, Phillips EJ (2022). Drug-Induced Hypersensitivity Syndrome (DIHS)/Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): Clinical Features and Pathogenesis. J Allergy Clin Immunol Pract, 10(5), 1155-1167.e5. https://doi.org/10.1016/j.jaip.2022.02.004 PMID: 35176506. PMCID: PMC9201940.

Koo G, Stollings JL, Lindsell C, Dear ML, Kripalani S, Nelson GE, McCoy AB, Rice TW, Phillips EJ, Stone CA Jr, Vanderbilt University Medical Center Learning Healthcare System (2022). Low-risk penicillin allergy delabeling through a direct oral challenge in immunocompromised and/or multiple drug allergy labeled patients in a critical care setting. J Allergy Clin Immunol Pract, 10(6), 1660-1663.e2. https://doi.org/10.1016/j.jaip.2022.01.041 PMID: 35131513. PMCID: PMC9188986.

Moustaki A, Crawford JC, Alli S, Fan Y, Boi S, Zamora AE, McDonald NMN, Wu G, Nakitandwe J, Newman S, Foy S, Silkov A, Thomas PG, Pappo A, Dyer MA, Stewart E, Federico S, Youngblood B (2022). Antigen cross-presentation in young tumor-bearing hosts promotes CD8(+) T cell terminal differentiation. Sci Immunol, 7(68), eabf6136. https://doi.org/10.1126/sciimmunol.abf6136 PMID: 35119937. PMCID: PMC8990347.

Buckner JH, Harrison OJ (2022). Th17 cells: from gut homeostasis to CNS pathogenesis. Trends Immunol, 43(3), 167-169. https://doi.org/10.1016/j.it.2022.01.005 PMID: 35058150. PMCID: PMC10029755.

Bruusgaard-Mouritsen MA, Koo G, Heinrichsen AS, Melchiors BB, Krantz MS, Plager JH, Boxer M, Phillips EJ, Stone CA Jr, Garvey LH (2022). Janssen COVID-19 vaccine tolerated in 10 patients with confirmed polyethylene glycol allergy. J Allergy Clin Immunol Pract, 10(3), 859-862. https://doi.org/10.1016/j.jaip.2021.12.025 PMID: 34979336. PMCID: PMC8719916.

Hertzman RJ, Deshpande P, White KD, Gangula R, Chopra A, Ram R, Zic JA, Zwerner JP, Gibson A, Phillips EJ (2022). Single-cell immunopathology of systemic contact allergy associated with corticosteroids. J Dermatol Sci, 105(2), 137-140. https://doi.org/10.1016/j.jdermsci.2021.12.005 PMID: 34974934. PMCID: PMC8920767.

Reshef YA, Rumker L, Kang JB, Nathan A, Korsunsky I, Asgari S, Murray MB, Moody DB, Raychaudhuri S (2022). Co-varying neighborhood analysis identifies cell populations associated with phenotypes of interest from single-cell transcriptomics. Nat Biotechnol, 40(3), 355-363. https://doi.org/10.1038/s41587-021-01066-4 PMID: 34675423. PMCID: PMC8930733.

Muthukumar T, Akat KM, Yang H, Schwartz JE, Li C, Bang H, Ben-Dov IZ, Lee JR, Ikle D, Demetris AJ, Tuschl T, Suthanthiran M (2022). Serum MicroRNA Transcriptomics and Acute Rejection or Recurrent Hepatitis C Virus in Human Liver Allograft Recipients: A Pilot Study. Transplantation, 106(4), 806-820. https://doi.org/10.1097/TP.0000000000003815 PMID: 33979314. PMCID: PMC8581074.

Lambert K, Diggins KE, Jones BE, Hundhausen C, Maerz MD, Hocking AM, Sanda S, Greenbaum CJ, Linsley PS, Cerosaletti K, Buckner JH (2022). IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation. Front Immunol, 13, 935394. https://doi.org/10.3389/fimmu.2022.935394 PMID: 35911690. PMCID: PMC9327741.

Speake C, Habib T, Lambert K, Hundhausen C, Lord S, Dufort MJ, Skinner SO, Hu A, Kinsman M, Jones BE, Maerz MD, Tatum M, Hocking AM, Nepom GT, Greenbaum CJ, Buckner JH (2022). IL-6-targeted therapies to block the cytokine or its receptor drive distinct alterations in T cell function. JCI Insight, 7(22). https://doi.org/10.1172/jci.insight.159436 PMID: 36282595. PMCID: PMC9746808.

Marwaha AK, Chow S, Pesenacker AM, Cook L, Sun A, Long SA, Yang JHM, Ward-Hartstonge KA, Williams E, Domingo-Vila C, Halani K, Harris KM, Tree TIM, Levings MK, Elliott T, Tan R, Dutz JP (2022). A phase 1b open-label dose-finding study of ustekinumab in young adults with type 1 diabetes. Immunother Adv, 2(1), ltab022. https://doi.org/10.1093/immadv/ltab022 PMID: 35072168. PMCID: PMC8769169.

Shaked O, Demetris J, Levitsky J, Feng S, Loza BL, Punch J, Reyes J, Klintmalm G, Jackson W, DesMarais M, Sayre P, Shaked A, Reddy KR (2022). Impact of Donor and Recipient Clinical Characteristics and Hepatic Histology on Steatosis/Fibrosis Following Liver Transplantation. Transplantation, 106(1), 106-116. https://doi.org/10.1097/TP.0000000000003681 PMID: 33982909. PMCID: PMC8349377.

Hübscher SG, Feng S, Gouw ASH, Haga H, Kang HJ, Kelly DA, Komuta M, Lesniak A, Popp BA, Verkade HJ, Yu E, Demetris AJ (2022). Standardizing the histological assessment of late posttransplantation biopsies from pediatric liver allograft recipients. Liver Transpl, 28(9), 1475-1489. https://doi.org/10.1002/lt.26482 PMID: 35429359.

Review & Commentary

Rosenberg A, Smilek DE (2024). Editorial: Innovative approaches to immune tolerance and regulation with gene, cellular, protein, and microbiome based therapeutics. Front Immunol, 15, 1382536. https://doi.org/10.3389/fimmu.2024.1382536 PMID: 38482015. PMCID: PMC10933116.

Russell WE, Moore DJ, Herold KC (2023). Response to Comment on Russell et al. Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial. Diabetes Care 2023;46:1005-1013. Diabetes Care, 46(11), e210-e211. https://doi.org/10.2337/dci23-0050 PMID: 37890101. PMCID: PMC10620531.

Durham SR, Shamji MH (2023). Allergen immunotherapy: past, present and future. Nat Rev Immunol, 23(5), 317-328. https://doi.org/10.1038/s41577-022-00786-1 PMID: 36253555. PMCID: PMC9575636.

Huffaker MF, Kanchan K, Bahnson HT, Baloh C, Lack G, Nepom GT, Mathias RA (2023). Incorporating genetics in identifying peanut allergy risk and tailoring allergen immunotherapy: A perspective on the genetic findings from the LEAP trial. J Allergy Clin Immunol, 151(4), 841-847. https://doi.org/10.1016/j.jaci.2022.12.819 PMID: 36732171.

Baloh CH, Mathias RA (2023). Recent progress in the genetic and epigenetic underpinnings of atopy. J Allergy Clin Immunol, 151(1), 60-69. https://doi.org/10.1016/j.jaci.2022.10.027 PMID: 36608983. PMCID: PMC9987265.

Nepom GT (2022). Synergistic targeting of immunologic pathways to empower durable tolerance therapies. Front Immunol, 13, 962177. https://doi.org/10.3389/fimmu.2022.962177 PMID: 36119087. PMCID: PMC9478166.

Huffaker MF (2022). The Prevention of Milk Allergy and the Risks of Stopping Too Soon. J Allergy Clin Immunol Pract, 10(1), 180-181. https://doi.org/10.1016/j.jaip.2021.09.011 PMID: 35000732.

Santos AF, Evans E, O'Rourke C, Bahnson HT, Lack G (2022). Reply to: Life-threatening anaphylaxis to peanut -- impossible to predict? J Allergy Clin Immunol, 149(3), 1129-1131. https://doi.org/10.1016/j.jaci.2021.12.766

Baloh CH, Huffaker MF, Laidlaw T (2022). Biomarkers and mechanisms of tolerance induction in food allergic patients drive new therapeutic approaches. Front Immunol, 13, 972103. https://doi.org/10.3389/fimmu.2022.972103 PMID: 36263023. PMCID: PMC9574092.

Huffaker MF, Sanda S, Chandran S, Chung SA, St Clair EW, Nepom GT, Smilek DE (2021). Approaches to Establishing Tolerance in Immune Mediated Diseases. Front Immunol, 12, 744804. https://doi.org/10.3389/fimmu.2021.744804 PMID: 34616405. PMCID: PMC8488342.

Podestà MA, Sykes M (2021). Chimerism-Based Tolerance to Kidney Allografts in Humans: Novel Insights and Future Perspectives. Front Immunol, 12, 791725. https://doi.org/10.3389/fimmu.2021.791725 PMID: 35069574. PMCID: PMC8767096.

Linsley PS, Greenbaum CJ, Nepom GT (2021). Uncovering Pathways to Personalized Therapies in Type 1 Diabetes. Diabetes, 70(4), 831-841. https://doi.org/10.2337/db20-1185 PMID: 33741606. PMCID: PMC7980192.

Krawiec M, Fisher HR, Du Toit G, Bahnson HT, Lack G (2021). Overview of oral tolerance induction for prevention of food allergy-Where are we now? Allergy, 76(9), 2684-2698. https://doi.org/10.1111/all.14758 PMID: 33539570.

Sykes M (2018). Immune monitoring of transplant patients in transient mixed chimerism tolerance trials. Hum Immunol, 79(5), 334-342. https://doi.org/10.1016/j.humimm.2017.12.011 PMID: 29289741. PMCID: PMC5924718.

Newell KA, Adams AB, Turka LA (2018). Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients. Hum Immunol, 79(5), 380-387. https://doi.org/10.1016/j.humimm.2018.02.007 PMID: 29448053. PMCID: PMC5924709.

Hemmings O, Kwok M, McKendry R, Santos AF (2018). Basophil Activation Test: Old and New Applications in Allergy. Curr Allergy Asthma Rep, 18(12), 77. https://doi.org/10.1007/s11882-018-0831-5 PMID: 30430289. PMCID: PMC6244909.

Fisher HR, Du Toit G, Bahnson HT, Lack G (2018). The challenges of preventing food allergy: Lessons learned from LEAP and EAT. Ann Allergy Asthma Immunol, 121(3), 313-319. https://doi.org/10.1016/j.anai.2018.06.008 PMID: 29909054.

Sampson HA, O'Mahony L, Burks AW, Plaut M, Lack G, Akdis CA (2018). Mechanisms of food allergy. J Allergy Clin Immunol, 141(1), 11-19. https://doi.org/10.1016/j.jaci.2017.11.005 PMID: 29307410.

Burks AW, Sampson HA, Plaut M, Lack G, Akdis CA (2018). Treatment for food allergy. J Allergy Clin Immunol, 141(1), 1-9. https://doi.org/10.1016/j.jaci.2017.11.004 PMID: 29307409.

Renz H, Allen KJ, Sicherer SH, Sampson HA, Lack G, Beyer K, Oettgen HC (2018). Food allergy. Nat Rev Dis Primers, 4, 17098. https://doi.org/10.1038/nrdp.2017.98 PMID: 29300005.

Nepom GT, Scott D (2017). Looking behind the data curtain. Cell Immunol, 319, 1-2. https://doi.org/10.1016/j.cellimm.2017.07.008 PMID: 28754194.

Zuber J, Sykes M (2017). Mechanisms of Mixed Chimerism-Based Transplant Tolerance. Trends Immunol, 38(11), 829-843. https://doi.org/10.1016/j.it.2017.07.008 PMID: 28826941. PMCID: PMC5669809.

Kean LS, Turka LA, Blazar BR (2017). Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy. Immunol Rev, 276(1), 192-212. https://doi.org/10.1111/imr.12523 PMID: 28258702. PMCID: PMC5338458.

Lawson K, Bahnson HT, Brittain E, Sever M, Du Toit G, Lack G, Keet C, Greenhawt M, Fleischer D, Chan ES, Venter C, Stukus D, Gupta R, Spergel J (2017). Letter of response to Greenhawt et al. 'LEAPing Through the Looking Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction on Peanut Tolerance after Early Peanut Introduction'. Allergy, 72(8), 1267-1271. https://doi.org/10.1111/all.13127 PMID: 28691223. PMCID: PMC5796413.

Bahnson HT, du Toit G, Lack G (2017). Statistical Considerations of Food Allergy Prevention Studies. J Allergy Clin Immunol Pract, 5(2), 274-282. https://doi.org/10.1016/j.jaip.2016.12.007 PMID: 28283152. PMCID: PMC5683073.

Wang J, Lack G (2017). Food Allergy: Unmet Needs and New Perspectives. J Allergy Clin Immunol Pract, 5(2), 295. https://doi.org/10.1016/j.jaip.2017.01.002 PMID: 28283155.

Asare AL, Carey VJ, Rotrosen D, Nepom GT (2016). Clinical trial data access: Opening doors with TrialShare. J Allergy Clin Immunol, 138(3), 724-726. https://doi.org/10.1016/j.jaci.2016.05.034 PMID: 27474121.

Buckner JH, Nepom GT (2016). Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes. J Autoimmun, 71, 44-50. https://doi.org/10.1016/j.jaut.2016.02.009 PMID: 26948997. PMCID: PMC4903876.

Ehlers MR (2016). Strategies for clinical trials in type 1 diabetes. J Autoimmun, 71, 88-96. https://doi.org/10.1016/j.jaut.2016.03.008 PMID: 27068279. PMCID: PMC4903883.

Ehlers MR (2016). Immune interventions to preserve β cell function in type 1 diabetes. J Investig Med, 64(1), 7-13. https://doi.org/10.1097/JIM.0000000000000227 PMID: 26225763. PMCID: PMC4732932.

du Toit G, Tsakok T, Lack S, Lack G (2016). Prevention of food allergy. J Allergy Clin Immunol, 137(4), 998-1010. https://doi.org/10.1016/j.jaci.2016.02.005 PMID: 27059727.

Ehlers MR, Rigby MR (2015). Targeting memory T cells in type 1 diabetes. Curr Diab Rep, 15(11), 84. https://doi.org/10.1007/s11892-015-0659-5 PMID: 26370695.

Demetris AJ, Zeevi A, O'Leary JG (2015). ABO-compatible liver allograft antibody-mediated rejection: an update. Curr Opin Organ Transplant, 20(3), 314-24. https://doi.org/10.1097/MOT.0000000000000194 PMID: 25944231. PMCID: PMC4646419.

Newell KA, Turka LA (2015). Tolerance signatures in transplant recipients. Curr Opin Organ Transplant, 20(4), 400-5. https://doi.org/10.1097/MOT.0000000000000207 PMID: 26107969. PMCID: PMC4524570.

McDonald-Hyman C, Turka LA, Blazar BR (2015). Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation. Sci Transl Med, 7(280), 280rv2. https://doi.org/10.1126/scitranslmed.aaa6853 PMID: 25810312. PMCID: PMC4425354.

Wofsy D, Diamond B, Houssiau FA (2015). Crossing the Atlantic: the Euro-Lupus Nephritis regimen in North America. Arthritis Rheumatol, 67(5), 1144-6. https://doi.org/10.1002/art.39067 PMID: 25779381. PMCID: PMC4523131.

Kimberly RP (2015). The Road Traveled: Genomics and Biomarkers in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 67(7), 1700-2. https://doi.org/10.1002/art.39148 PMID: 25891203.

Smilek DE, St Clair EW (2015). Solving the puzzle of autoimmunity: critical questions. F1000Prime Rep, 7, 17. https://doi.org/10.12703/P7-17 PMID: 25750735. PMCID: PMC4335798.

Rigby MR, Ehlers MR (2014). Targeted immune interventions for type 1 diabetes: not as easy as it looks! Curr Opin Endocrinol Diabetes Obes, 21(4), 271-8. https://doi.org/10.1097/MED.0000000000000075 PMID: 24983393. PMCID: PMC4133939.

Sykes M (2014). Transplantation: moving to the next level. Immunol Rev, 258(1), 5-11. https://doi.org/10.1111/imr.12161 PMID: 24517422. PMCID: PMC4038030.

Kawai T, Leventhal J, Madsen JC, Strober S, Turka LA, Wood KJ (2014). Tolerance: one transplant for life. Transplantation, 98(2), 117-21. https://doi.org/10.1097/TP.0000000000000260 PMID: 24926829. PMCID: PMC4101034.

Smilek DE, Ehlers MR, Nepom GT (2014). Restoring the balance: immunotherapeutic combinations for autoimmune disease. Dis Model Mech, 7(5), 503-13. https://doi.org/10.1242/dmm.015099 PMID: 24795433. PMCID: PMC4007402.

Ehlers MR (2014). Immune-modulating effects of alpha-1 antitrypsin. Biol Chem, 395(10), 1187-93. https://doi.org/10.1515/hsz-2014-0161 PMID: 24854541. PMCID: PMC4237306.

Sosinowski T, Eisenbarth GS (2013). Type 1 diabetes: primary antigen/peptide/register/trimolecular complex. Immunol Res, 55(1-3), 270-6. https://doi.org/10.1007/s12026-012-8367-6 PMID: 22956469. PMCID: PMC3936464.

Nepom GT, Ehlers M, Mandrup-Poulsen T (2013). Anti-cytokine therapies in T1D: Concepts and strategies. Clin Immunol, 149(3), 279-85. https://doi.org/10.1016/j.clim.2013.02.003 PMID: 23510726. PMCID: PMC3700624.

Kawai T, Sachs DH, Sykes M, Cosimi AB, Immune Tolerance Network (2013). HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med, 368(19), 1850-2. https://doi.org/10.1056/NEJMc1213779 PMID: 23656665. PMCID: PMC3760499.

Tang Q, Bluestone JA (2013). Regulatory T-cell therapy in transplantation: moving to the clinic. Cold Spring Harb Perspect Med, 3(11). https://doi.org/10.1101/cshperspect.a015552 PMID: 24186492. PMCID: PMC3808774.

Demetris AJ, Isse K (2013). Tissue biopsy monitoring of operational tolerance in liver allograft recipients. Curr Opin Organ Transplant, 18(3), 345-53. https://doi.org/10.1097/MOT.0b013e3283615d48 PMID: 23619515.

Kawai T, Sachs DH (2013). Tolerance induction: hematopoietic chimerism. Curr Opin Organ Transplant, 18(4), 402-7. https://doi.org/10.1097/MOT.0b013e328363621d PMID: 23838644.

Zarin DA (2013). Participant-level data and the new frontier in trial transparency. N Engl J Med, 369(5), 468-9. https://doi.org/10.1056/NEJMe1307268 PMID: 23902488.

Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P (2013). Prophylactic use of sublingual allergen immunotherapy in high-risk children: a pilot study. J Allergy Clin Immunol, 132(4), 991-3.e1. https://doi.org/10.1016/j.jaci.2013.04.049 PMID: 23768574.

Ehlers MR, Nepom GT (2012). Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience. Rev Diabet Stud, 9(4), 359-71. https://doi.org/10.1900/RDS.2012.9.359 PMID: 23804273. PMCID: PMC3740703.

Eisenbarth GS (2012). Prevention of type 1A diabetes mellitus. Endocr Pract, 18(5), 745-9. https://doi.org/10.4158/EP12080.OR PMID: 22548954. PMCID: PMC4976770.

Pietropaolo M, Towns R, Eisenbarth GS (2012). Humoral autoimmunity in type 1 diabetes: prediction, significance, and detection of distinct disease subtypes. Cold Spring Harb Perspect Med, 2(10). https://doi.org/10.1101/cshperspect.a012831 PMID: 23028135. PMCID: PMC3475400.

Isse K, Lesniak A, Grama K, Roysam B, Minervini MI, Demetris AJ (2012). Digital transplantation pathology: combining whole slide imaging, multiplex staining and automated image analysis. Am J Transplant, 12(1), 27-37. https://doi.org/10.1111/j.1600-6143.2011.03797.x PMID: 22053785. PMCID: PMC3627485.

Tchao NK, Turka LA (2012). Lymphodepletion and homeostatic proliferation: implications for transplantation. Am J Transplant, 12(5), 1079-90. https://doi.org/10.1111/j.1600-6143.2012.04008.x PMID: 22420320.

Nepom GT, St Clair EW, Turka LA (2011). Challenges in the pursuit of immune tolerance. Immunol Rev, 241(1), 49-62. https://doi.org/10.1111/j.1600-065X.2011.01003.x PMID: 21488889. PMCID: PMC3092524.

Kawai T, Cosimi AB, Sachs DH (2011). Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism. Curr Opin Organ Transplant, 16(4), 366-71. https://doi.org/10.1097/MOT.0b013e3283484b2c PMID: 21666482. PMCID: PMC3151013.

Newell KA, Phippard D, Turka LA (2011). Regulatory cells and cell signatures in clinical transplantation tolerance. Curr Opin Immunol, 23(5), 655-9. https://doi.org/10.1016/j.coi.2011.07.008 PMID: 21982510.

Bluestone JA, Krensky AM, Turka LA, Rotrosen D, Matthews JB (2010). Ten years of the Immune Tolerance Network: an integrated clinical research organization. Sci Transl Med, 2(19), 19cm7. https://doi.org/10.1126/scitranslmed.3000672 PMID: 20371484.

Bluestone JA, Auchincloss H, Nepom GT, Rotrosen D, St Clair EW, Turka LA (2010). The Immune Tolerance Network at 10 years: tolerance research at the bedside. Nat Rev Immunol, 10(11), 797-803. https://doi.org/10.1038/nri2869 PMID: 20972473.

Isse K, Grama K, Abbott IM, Lesniak A, Lunz JG, Lee WM, Specht S, Corbitt N, Mizuguchi Y, Roysam B, Demetris AJ (2010). Adding value to liver (and allograft) biopsy evaluation using a combination of multiplex quantum dot immunostaining, high-resolution whole-slide digital imaging, and automated image analysis. Clin Liver Dis, 14(4), 669-85. https://doi.org/10.1016/j.cld.2010.07.004 PMID: 21055689.

Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group (2010). Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group. Clin Exp Immunol, 160(2), 176-84. https://doi.org/10.1111/j.1365-2249.2010.04153.x PMID: 20629979. PMCID: PMC2857940.

Turka LA, Wood K, Bluestone JA (2010). Bringing transplantation tolerance into the clinic: lessons from the ITN and RISET for the Establishment of Tolerance consortia. Curr Opin Organ Transplant, 15(4), 441-8. https://doi.org/10.1097/MOT.0b013e32833bd371 PMID: 20631613.

Seyfert-Margolis V, Turka LA (2008). Marking a path to transplant tolerance. J Clin Invest, 118(8), 2684-6. https://doi.org/10.1172/JCI36552 PMID: 18654643. PMCID: PMC2483691.

St Clair EW, Turka LA, Saxon A, Matthews JB, Sayegh MH, Eisenbarth GS, Bluestone J (2007). New reagents on the horizon for immune tolerance. Annu Rev Med, 58, 329-46. https://doi.org/10.1146/annurev.med.58.061705.145449 PMID: 16987079.

Miao D, Yu L, Eisenbarth GS (2007). Role of autoantibodies in type 1 diabetes. Front Biosci, 12, 1889-98. https://doi.org/10.2741/2195 PMID: 17127428.

Afzali B, Lechler RI, Hernandez-Fuentes MP (2007). Allorecognition and the alloresponse: clinical implications. Tissue Antigens, 69(6), 545-56. https://doi.org/10.1111/j.1399-0039.2007.00834.x PMID: 17498264.

Knechtle SJ (2005). Development of tolerogenic strategies in the clinic. Philos Trans R Soc Lond B Biol Sci, 360(1461), 1739-46. https://doi.org/10.1098/rstb.2005.1705 PMID: 16147538. PMCID: PMC1569535.

Cosimi AB, Sachs DH (2004). Mixed chimerism and transplantation tolerance. Transplantation, 77(6), 943-6. https://doi.org/10.1097/01.tp.0000117779.23431.3f PMID: 15077044.

Eisenbarth GS, Jasinski JM (2004). Disease prevention with islet autoantigens. Endocrinol Metab Clin North Am, 33(1), 59-73, viii. https://doi.org/10.1016/j.ecl.2003.12.005 PMID: 15053895.

Devendra D, Liu E, Eisenbarth GS (2004). Type 1 diabetes: recent developments. BMJ, 328(7442), 750-4. https://doi.org/10.1136/bmj.328.7442.750 PMID: 15044291. PMCID: PMC381328.

Devendra D, Eisenbarth GS (2004). Interferon alpha--a potential link in the pathogenesis of viral-induced type 1 diabetes and autoimmunity. Clin Immunol, 111(3), 225-33. https://doi.org/10.1016/j.clim.2004.01.008 PMID: 15183143.

Eisenbarth GS, Gottlieb PA (2004). Autoimmune polyendocrine syndromes. N Engl J Med, 350(20), 2068-79. https://doi.org/10.1056/NEJMra030158 PMID: 15141045.

Saxon A (2004). What impact will the immune tolerance network have on the future treatment of allergic diseases? Clin Exp Allergy, 34(11), 1657-9. https://doi.org/10.1111/j.1365-2222.2004.02113.x PMID: 15544586.

Nepom GT (2003). MHC multimers: expanding the clinical toolkit. Clin Immunol, 106(1), 1-4. https://doi.org/10.1016/s1521-6616(02)00014-1 PMID: 12584043.

Matthews JB, Ramos E, Bluestone JA (2003). Clinical trials of transplant tolerance: slow but steady progress. Am J Transplant, 3(7), 794-803. https://doi.org/10.1046/j.1600-6135.2003.0154.x PMID: 12814471.

Rotrosen D, Matthews JB, Bluestone JA (2002). The immune tolerance network: a new paradigm for developing tolerance-inducing therapies. J Allergy Clin Immunol, 110(1), 17-23. https://doi.org/10.1067/mai.2002.124258 PMID: 12110811.

Bluestone JA, Matthews J (2001). The Immune Tolerance Network: tolerance at the crossroads. Philos Trans R Soc Lond B Biol Sci, 356(1409), 773-6. https://doi.org/10.1098/rstb.2001.0847 PMID: 11375080. PMCID: PMC1088464.

Bluestone JA, Matthews JB (2000). The immune tolerance network--an NIH/JDF-supported initiative to bring tolerance research into the clinic: a major new resource for clinical immunologists. Clin Immunol, 96(3), 171-3. https://doi.org/10.1006/clim.2000.4892 PMID: 10964534.

Manuscript

Aranow C, Dall'Era M, Byron M, Ding L, Smilek D, Diamond B, Wofsy D (2018). FRI0305 Phase 2 trial of induction therapy with anti-cd20 (RITUXIMAB) followed by maintenance therapy with anti-baff (BELIMUMAB) in patients with active lupus nephritis. Ann Rheum Dis, 690. https://dx.doi.org/10.1136/annrheumdis-2018-eular.5711

Specks U, Merkel PA, Hoffman GS, Langford CA, Spiera R, Seo P, Kallenberg CGM, St. Clair EW, Ding L, Webber L, Mokhtarani M, Tchao NK, Sayre PH, Seyfert-Margolis V, Ikle D, Brunetta P, Zhang D, Sejismundo L, Mueller M, Stone JH (2011). Design of the Rituximab in ANCA-associated Vasculitis (RAVE) Trial. The Open Arthritis Journal, 4 (1), 1-18. https://doi.org/10.2174/1876539401104010001

Vandenbark, A.A., Culbertson, N.E. (2007). Trivalent T Cell Receptor Peptide Vaccine for Treatment of Multiple Sclerosis Targets Predominant V Genes Widely Implicated in Autoimmune Diseases and Allergy. In: Zhang, J. (eds) Immune Regulation and Immunotherapy in Autoimmune Disease. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-36003-4_16

Commentary

No items found.

Abstract

Aranow, C, Diamond, B, Wofsy, D, Byron, M, Smilek, D, Ding, L, Tosta, P, Ryker, K, Gao, W, Dall’Era, M, Features of patients screened for calibrate (rituximab plus cyclophosphamide followed by belimumab for the treatment of lupus nephritis); hypogammaglobulinemia is frequent in patients with marked elevation of urinary protein. https://doi.org/10.1136/lupus-2016-000179.74