Nir Hacohen, PhD

From the Harvard website: The Hacohen lab uses systems-wide genetic and biochemical approaches to describe the mechanisms underlying specificity in pathogen-sensing pathways, the interactions of pathogens with their hosts and the initiation of autoimmunity. The major projects in the lab focus on how: (1) TLRs and other pathogen sensors achieve specificity in their induction of gene expression; (2) influenza virus modulates host responses; (3) to develop systematic methods to reconstruct signaling and transcriptional networks.