Today's Date
Ten Year Symposium - Keynote Address
The keynote address from the Ten Year Symposium.
Jean-François Bach, MD, DSc is Professor of Immunology at Necker Hospital in Paris and is the Secrétaire Perpétuel de l’Académie des Sciences. He has had a long standing interest in organ transplantation and autoimmune diseases, notably insulin-dependent diabetes mellitus (IDDM). His main contributions include the description of E rosettes, the discovery of thymulin, a thymic peptide involved in T cell differentiation, the description and characterization of regulatory T cells in autoimmunity and the first demonstration of the therapeutic effect of cyclosporin A in recently diagnosed diabetic patients. More recently, he has described a new method of tolerance induction in type 1 diabetes in collaboration with Lucienne Chatenoud using an anti-CD3 monoclonal antibody. This was first shown to work in the NOD mouse and extrapolated to human diabetes in a phase II trial.
Presenters
Jean-Francois Bach, MD, DSc