Request for Proposals: ITN Seeks Antigen-Specific T Cell Tolerance Assays for Myelin-Associated Antigens in Multiple Sclerosis

January 27, 2015

The ITN has an interest in antigen-specific T cell tolerance in multiple sclerosis, an autoimmune disease in which autoreactive T cells specific for myelin-associated antigens are thought to play a role in pathogenesis. Assessment of antigen-specific tolerance in multiple sclerosis will require reliable assays to detect and phenotype T cell responses to myelin-associated antigens in a clinical trial setting. To this end, the ITN is seeking assays for assessing functional tolerance and biomarkers of tolerance in antigen-specific CD4 and CD8 effector and regulatory T cells.  

Deadline: February 13, 2015

Detailed information and instructions: RFP - T Cell Tolerance Assay for Myelin Associated Antigens

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