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The results of an Immune Tolerance Network (ITN) study, published in the October 5, 2006 issue of the New England Journal of Medicine suggest that a six-week experimental allergy treatment can relieve hay fever symptoms for at least two years. The researchers believe that the six-injection immunotherapy regimen with a novel DNA-based drug known as ‘AIC’ could offer a significant improvement over traditional allergen immunotherapy, which can require several years of weekly or bi-weekly injections.

The results of the world's first multicenter clinical trial of islet transplantation have confirmed the technique's potential benefits in patients with difficult-to-control type 1 (or "juvenile") diabetes.

The Juvenile Diabetes Research Foundation (JDRF), the world's leading charitable supporter of research into type 1 diabetes and its complications, today announced a new, 5-year $15 million joint funding program with the NIH-supported Immune Tolerance Network (ITN) that is aimed at accelerating the pace of clinical research towards a cure for type 1 diabetes.  The JDRF-ITN Partnership in Immune Tolerance program will fund early-stage clinical trials and late stage preclinical development of potential immune tolerance-inducing treatments for type 1 diabetes.&nb

The Immune Tolerance Network today released updated results from its multicenter clinical trial of the Edmonton Protocol for islet transplantation. The results provide further confirmation that transplantation of pancreatic islet cells can safely and effectively eliminate the need for daily insulin injections in patients with type 1 diabetes. The expanded results, encompassing the entire cohort of 36 patients enrolled in the trial also confirms that the technique can be successfully applied at multiple clinical centers.