The Immune Tolerance Network (ITN) is the product of several years of planning by the National Institutes of Health (NIH) and the extramural research community. We are grateful for the effort and insight of our sponsors, who continue to support the mission of the Network.
The ITN is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID, NIH), with support from JDRF. Additional funding has also been provided through the special type 1 diabetes appropriation overseen by the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK, NIH).
National Institute of Allergy and Infectious Diseases
NIAID provides the major support for scientists conducting research aimed at developing better ways to diagnose, treat and prevent the many infectious, immunologic and allergic diseases that afflict people worldwide. NIAID is composed of three extramural divisions: the Division of AIDS; the Division of Allergy, Immunology and Transplantation and the Division of Microbiology and Infectious Diseases. In addition, NIAID scientists conduct intramural research in laboratories located in Bethesda, Rockville and Frederick, Maryland, and in Hamilton, Montana.
JDRF is a not-for-profit, voluntary health agency with chapters and affiliates throughout the world. JDRF's main objective is to support and fund research to find a cure for diabetes and its complications. JDRF gives more money directly to diabetes research than any other private health agency in the world. The organization awards research grants for laboratory and clinical investigations and sponsors a variety of career development and research training programs for new and established investigators. JDRF also sponsors international workshops and conferences for biomedical researchers. Individual chapters offer support groups and other activities for families affected by diabetes.
JDRF also sponsors the ITN's Type 1 Diabetes Preclinical Consortium, an initiative to generate preclinical data to support combination therapy studies in type 1 diabetes. The consortium is a multi-center network of geographically diverse research laboratories that use standardized SOPs to enable data pooling and reproducibility across sites. The goal of the consortium is to generate high-quality, FDA-acceptable preclinical data to support attractive combination therapy approaches for type 1 diabetes.
FOCiS Member Society
The ITN is a Federation of Clinical Immunology Societies (FOCIS) member society. FOCiS exists to improve human health through immunology by fostering interdisciplinary approaches to both understand and treat immune-based diseases.