Publications
Articles
Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes
(2020). Nat Immunol, epub ahead of print. http://dx.doi.org/10.1038/s41590-020-0633-5, PMID: 32231298
Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Chase Crawford J, Alfei F, Alli S, Pereira Ribeiro S, Castellaw AH, McGargill MA, Jin H, Boi SH, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly R, Zehn D, James E, Nepom GT, Youngblood B
[PubMed]
[Citation View]
Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Chase Crawford J, Alfei F, Alli S, Pereira Ribeiro S, Castellaw AH, McGargill MA, Jin H, Boi SH, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly R, Zehn D, James E, Nepom GT, Youngblood B (2020). Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nat Immunol, epub ahead of print.
Nasal Allergen Challenge and Environmental Exposure Chamber Challenge: A Randomized Trial Comparing Clinical and Biological Responses to Cat Allergen
(2020). J Allergy Clin Immunol, S0091-6749 (20), 30332-8. http://dx.doi.org/10.1016/j.jaci.2020.02.024, PMID: 32169380
Larson D, Patel P, Salapatek AM, Couroux P, Whitehouse D, Pina A, Johnson JL, Sever ML, Sanda S, Poyser J, Allio T, Scadding GW, Qin T, Shamji MH, Kwok WW, James E, French D, Lelic A, Larché M, Altman MC, Togias A, Durham SR
[PubMed]
[Citation View]
Larson D, Patel P, Salapatek AM, Couroux P, Whitehouse D, Pina A, Johnson JL, Sever ML, Sanda S, Poyser J, Allio T, Scadding GW, Qin T, Shamji MH, Kwok WW, James E, French D, Lelic A, Larché M, Altman MC, Togias A, Durham SR (2020). Nasal Allergen Challenge and Environmental Exposure Chamber Challenge: A Randomized Trial Comparing Clinical and Biological Responses to Cat Allergen. J Allergy Clin Immunol, S0091-6749 (20), 30332-8.
Association of Respiratory Allergy, Asthma and Expression of the SARS-CoV-2 Receptor, ACE2
(2020). J Allergy Clin Immunol, epub ahead of print. http://dx.doi.org/10.1016/j.jaci.2020.04.009, PMID: 32333915, PMCID: PMC7175851
Jackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, Ober C, Gergen PJ, Becker P, Togias A, Gern JE, Altman MC
[Reprint] [PubMed]
[Citation View]
Jackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, Ober C, Gergen PJ, Becker P, Togias A, Gern JE, Altman MC (2020). Association of Respiratory Allergy, Asthma and Expression of the SARS-CoV-2 Receptor, ACE2. J Allergy Clin Immunol, epub ahead of print.
Post-transplant biopsy risk for stable long-term pediatric liver transplant recipients: 451 percutaneous biopsies from two multi-center immunosuppression withdrawal trials
(2019). Am J Transplant. http://dx.doi.org/10.1111/ajt.15255, PMID: 30614623
Perito ER, Martinez M, Turmelle YP, Mason K, Spain KM, Bucuvalas JC, Feng S
[PubMed]
[Citation View]
Perito ER, Martinez M, Turmelle YP, Mason K, Spain KM, Bucuvalas JC, Feng S (2019). Post-transplant biopsy risk for stable long-term pediatric liver transplant recipients: 451 percutaneous biopsies from two multi-center immunosuppression withdrawal trials. Am J Transplant.
Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance
(2019). J Immunol, e pub. http://dx.doi.org/10.4049/jimmunol.1801425, PMID: 30683697
Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E
[Reprint] [PubMed]
[Citation View]
Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E (2019). Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance. J Immunol, e pub.
Outcomes of immunosuppression minimization and withdrawal early after liver transplantation
(2019). Am J Transplant, 19 (5), 1397‐1409. http://dx.doi.org/10.1111/ajt.15205, PMID: 30506630, PMCID: PMC6482056
Shaked A, DesMarais MR, Kopetskie H, Feng S, Punch J, Levitsky J, Reyes J, Klintmalm G, Demetris AJ, Burrell BE, Priore A, Bridges ND, Sayre PH
[Reprint] [PubMed]
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Shaked A, DesMarais MR, Kopetskie H, Feng S, Punch J, Levitsky J, Reyes J, Klintmalm G, Demetris AJ, Burrell BE, Priore A, Bridges ND, Sayre PH (2019). Outcomes of immunosuppression minimization and withdrawal early after liver transplantation. Am J Transplant, 19 (5), 1397‐1409.
Cell type–specific immune phenotypes predict loss of insulin secretion in new-onset type 1 diabetes
(2019). JCI Insight, 4 (4), e125556. http://dx.doi.org/10.1172/jci.insight.125556, PMID: 30830868, PMCID: PMC6478408
Dufort MJ, Greenbaum CJ, Speake C, Linsley PS
[Reprint] [PubMed]
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Dufort MJ, Greenbaum CJ, Speake C, Linsley PS (2019). Cell type–specific immune phenotypes predict loss of insulin secretion in new-onset type 1 diabetes. JCI Insight, 4 (4), e125556.
B lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes
(2019). JCI Insight, 4 (4), e126136. http://dx.doi.org/10.1172/jci.insight.126136, PMID: 30830871, PMCID: PMC6478438
Linsley PS, Greenbaum CJ, Speake C, Long SA, Dufort MJ
[Reprint] [PubMed]
[Citation View]
Linsley PS, Greenbaum CJ, Speake C, Long SA, Dufort MJ (2019). B lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes. JCI Insight, 4 (4), e126136.
The MALT1 locus and Peanut Avoidance in the Risk for Peanut Allergy
(2019). J Allergy Clin Immunol, 19, 30279. http://dx.doi.org/10.1016/j.jaci.2019.02.016, PMID: 30825465
Winters A, Bahnson HT, Ruczinski I, Boorgula MP, Malley C, Keramati AR, Chavan S, Larson D, Cerosaletti K, Sayre PH, Plaut M, Du Toit G, Lack G, Barnes KC, Nepom GT, Mathias RA, Immune Tolerance Network LEAP Study Team
[Reprint] [PubMed]
[Citation View]
Winters A, Bahnson HT, Ruczinski I, Boorgula MP, Malley C, Keramati AR, Chavan S, Larson D, Cerosaletti K, Sayre PH, Plaut M, Du Toit G, Lack G, Barnes KC, Nepom GT, Mathias RA, Immune Tolerance Network LEAP Study Team (2019). The MALT1 locus and Peanut Avoidance in the Risk for Peanut Allergy. J Allergy Clin Immunol, 19, 30279.
Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression
(2019). Diabetes, epub ahead of print. http://dx.doi.org/10.2337/db18-1081, PMID: 30894366
Habib T, Long SA, Samuels PL, Brahmandam A, Tatum M, Funk A, Hocking AM, Cerosaletti K, Mason MT, Whalen E, Rawlings DJ, Greenbaum CJ, Buckner JH, the Type 1 Diabetes TrialNet Study Group
[PubMed]
[Citation View]
Habib T, Long SA, Samuels PL, Brahmandam A, Tatum M, Funk A, Hocking AM, Cerosaletti K, Mason MT, Whalen E, Rawlings DJ, Greenbaum CJ, Buckner JH, the Type 1 Diabetes TrialNet Study Group (2019). Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression. Diabetes, epub ahead of print.
Treg gene signatures predict and measure type 1 diabetes trajectory
(2019). JCI Insight, 4 (6), e123879. http://dx.doi.org/10.1172/jci.insight.123879, PMID: 30730852, PMCID: PMC6483004
Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliot T, Dutz JP, Tebbutt SJ, Levings MK
[Reprint] [PubMed]
[Citation View]
Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliot T, Dutz JP, Tebbutt SJ, Levings MK (2019). Treg gene signatures predict and measure type 1 diabetes trajectory. JCI Insight, 4 (6), e123879.
Low-dose Anti-Thymocyte Globulin Preserves C-Peptide and Reduces A1c in New Onset Type 1 Diabetes: Two Year Clinical Trial Data
(2019). Diabetes, db190057. http://dx.doi.org/10.2337/db19-0057, PMID: 30967424
Haller MJ, Long SA, Blanchfield JL, Schatz DA, Skyler JS, Krischer J, Bundy BN, Geyer SM, Warnock MV, Miller J, Atkinson MA, Becker DJ, Baidal DA, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Herold KC, Marks JB, Moran A, Rodriguez H, Russell WE, Wilson DM, Greenbaum CJ, Type 1 Diabetes TrialNet ATG-GCSF Study Group
[Reprint] [PubMed]
[Citation View]
Haller MJ, Long SA, Blanchfield JL, Schatz DA, Skyler JS, Krischer J, Bundy BN, Geyer SM, Warnock MV, Miller J, Atkinson MA, Becker DJ, Baidal DA, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Herold KC, Marks JB, Moran A, Rodriguez H, Russell WE, Wilson DM, Greenbaum CJ, Type 1 Diabetes TrialNet ATG-GCSF Study Group (2019). Low-dose Anti-Thymocyte Globulin Preserves C-Peptide and Reduces A1c in New Onset Type 1 Diabetes: Two Year Clinical Trial Data. Diabetes, db190057.
Self-tolerance curtails the B cell repertoire to microbial epitopes
(2019). JCI Insight, 4 (10). http://dx.doi.org/10.1172/jci.insight.122551, PMID: 31092727
Watanabe A, Su KY, Kuraoka M, Yang G, Reynolds AE, Schmidt AG, Harrison SC, Haynes BF, St Clair EW, Kelsoe G
[Reprint] [PubMed]
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Watanabe A, Su KY, Kuraoka M, Yang G, Reynolds AE, Schmidt AG, Harrison SC, Haynes BF, St Clair EW, Kelsoe G (2019). Self-tolerance curtails the B cell repertoire to microbial epitopes. JCI Insight, 4 (10).
Association of Staphylococcus aureus colonization with food allergy occurs independently of eczema severity
(2019). The Journal of Allergy and Clinical Immunology. http://dx.doi.org/10.1016/j.jaci.2019.04.025
Tsilochristou O, Du Toit G, Sayre PH, Roberts G, Lawson K, Sever ML, Bahnson HT, Radulovic S, Basting M, Plaut M, Lack G, Immune Tolerance Network LEAP Study Team
Tsilochristou O, Du Toit G, Sayre PH, Roberts G, Lawson K, Sever ML, Bahnson HT, Radulovic S, Basting M, Plaut M, Lack G, Immune Tolerance Network LEAP Study Team (2019). Association of Staphylococcus aureus colonization with food allergy occurs independently of eczema severity. The Journal of Allergy and Clinical Immunology.
Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes
(2019). Genes Immun, 20 (4), 293-307. http://dx.doi.org/10.1038/s41435-018-0032-1, PMID: 29925930, PMCID: PMC6477779
Linsley PS, Greenbaum CJ, Rosasco M, Presnell S, Herold KC, Dufort MJ
[Reprint] [PubMed]
[Citation View]
Linsley PS, Greenbaum CJ, Rosasco M, Presnell S, Herold KC, Dufort MJ (2019). Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes. Genes Immun, 20 (4), 293-307.
Disease Activity, ANCA-Type, and Lipid Levels in ANCA-Associated Vasculitis.
(2019). Arthritis Rheumatol, epub ahead of print. http://dx.doi.org/10.1002/art.41006, PMID: 31162829
Wallace ZS, Fu X, Liao K, Kallenberg CGM, Langford CA, Merkel PA, Monach P, Seo P, Specks U, Spiera R, St Clair EW, Zhang Y, Choi H, Stone JH
[PubMed]
[Citation View]
Wallace ZS, Fu X, Liao K, Kallenberg CGM, Langford CA, Merkel PA, Monach P, Seo P, Specks U, Spiera R, St Clair EW, Zhang Y, Choi H, Stone JH (2019). Disease Activity, ANCA-Type, and Lipid Levels in ANCA-Associated Vasculitis.. Arthritis Rheumatol, epub ahead of print.
Enhancing the Value of Histopathological Assessment of Allograft Biopsy Monitoring
(2019). Transplantation, epub ahead of print. http://dx.doi.org/10.1097/TP.0000000000002656, PMID: 30768568
Wood-Trageser MA, Lesniak A, Demetris AJ
[PubMed]
[Citation View]
Wood-Trageser MA, Lesniak A, Demetris AJ (2019). Enhancing the Value of Histopathological Assessment of Allograft Biopsy Monitoring. Transplantation, epub ahead of print.
The Association of Pulmonary Haemorrhage, Positive PR3-ANCA and Urinary Red Blood Cell Casts with Venous Thromboembolism in ANCA-Associated Vasculitis
(2019). Arthritis Rheumatol., epub ahead of print. http://dx.doi.org/10.1002/art.41017, PMID: 31216123
Kronbichler A, Leierer J, Shin JI, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman M, Kallenberg CGM, St Clair EW, Brunetta P, Fervenza FC, Geetha D, Keogh KA, Monach PA, Ytterberg SR, Mayer G, Specks U, Stone JH, RAVE-ITN Research Group
[PubMed]
[Citation View]
Kronbichler A, Leierer J, Shin JI, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman M, Kallenberg CGM, St Clair EW, Brunetta P, Fervenza FC, Geetha D, Keogh KA, Monach PA, Ytterberg SR, Mayer G, Specks U, Stone JH, RAVE-ITN Research Group (2019). The Association of Pulmonary Haemorrhage, Positive PR3-ANCA and Urinary Red Blood Cell Casts with Venous Thromboembolism in ANCA-Associated Vasculitis. Arthritis Rheumatol., epub ahead of print.
Elicited and pre‐existing anti‐Neu5Gc antibodies differentially affect human endothelial cells transcriptome
(2019). Xenotransplantation, epub ahead of print. http://dx.doi.org/10.1111/xen.12535, PMID: 31293002
Le Berre L, Danger R, Mai HL, Amon R, Leviatan Ben-Ayre S, Bruneau S, Senage T, Perreault H, Teraiya M, Nguyen TVH, Le Tourneau T, Yu H, Chen X, Galli C, Roussel JC, Manez R, Costa C, Brouard S, Galinanes, M, Harris KM, Gitelman S, Cozzi E, Charreau B, Padler-Karavani V, Soulillou JP
[PubMed]
[Citation View]
Le Berre L, Danger R, Mai HL, Amon R, Leviatan Ben-Ayre S, Bruneau S, Senage T, Perreault H, Teraiya M, Nguyen TVH, Le Tourneau T, Yu H, Chen X, Galli C, Roussel JC, Manez R, Costa C, Brouard S, Galinanes, M, Harris KM, Gitelman S, Cozzi E, Charreau B, Padler-Karavani V, Soulillou JP (2019). Elicited and pre‐existing anti‐Neu5Gc antibodies differentially affect human endothelial cells transcriptome. Xenotransplantation, epub ahead of print.
The association of serum interleukin-6 levels with clinical outcomes in antineutrophil cytoplasmic antibody-associated vasculitis
(2019). J Autoimmun, epub ahead of print. http://dx.doi.org/10.1016/j.jaut.2019.07.001, PMID: 31320177
Berti A, Warner RL, Johnson KJ, Cornec D, Schroeder DR, Kabat BF, Langford CA, Kallenberg CGM, Seo P, Spiera RF, St Clair EW, Fervenza FC, Stone JH, Monach PA, Specks U, Merkel PA, RAVE-ITN Research Group
[PubMed]
[Citation View]
Berti A, Warner RL, Johnson KJ, Cornec D, Schroeder DR, Kabat BF, Langford CA, Kallenberg CGM, Seo P, Spiera RF, St Clair EW, Fervenza FC, Stone JH, Monach PA, Specks U, Merkel PA, RAVE-ITN Research Group (2019). The association of serum interleukin-6 levels with clinical outcomes in antineutrophil cytoplasmic antibody-associated vasculitis. J Autoimmun, epub ahead of print.
Transplantation tolerance in nonhuman primates and humans.
(2019). Bone Marrow Transplant., 54 (Suppl 2), 815-821. http://dx.doi.org/10.1038/s41409-019-0620-3, PMID: 31431694
Sykes M, Griesemer AD
[Reprint] [PubMed]
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Sykes M, Griesemer AD (2019). Transplantation tolerance in nonhuman primates and humans.. Bone Marrow Transplant., 54 (Suppl 2), 815-821.
Deletion of donor-reactive T cell clones following human liver transplantation.
(2019). Am J Transplant., epub ahead of print. http://dx.doi.org/10.1111/ajt.15592, PMID: 31509321
Savage TM, Shonts BA, Lau S, Obradovic A, Robins H, Shaked A, Shen Y, Sykes M
[PubMed]
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Savage TM, Shonts BA, Lau S, Obradovic A, Robins H, Shaked A, Shen Y, Sykes M (2019). Deletion of donor-reactive T cell clones following human liver transplantation.. Am J Transplant., epub ahead of print.
Systematic Assessment of Immune Marker Variation in Type 1 Diabetes: A Prospective Longitudinal Study.
(2019). Front Immunol, 10, 2023. http://dx.doi.org/10.3389/fimmu.2019.02023
Speake C, Bahnson HT, Wesley JD, Perdue N, Friedrich D, Pham MN, Lanxon-Cookson E, Kwok WW, Sehested Hanson B, von Herrath M, Greenbaum CJ
Speake C, Bahnson HT, Wesley JD, Perdue N, Friedrich D, Pham MN, Lanxon-Cookson E, Kwok WW, Sehested Hanson B, von Herrath M, Greenbaum CJ (2019). Systematic Assessment of Immune Marker Variation in Type 1 Diabetes: A Prospective Longitudinal Study. . Front Immunol, 10, 2023.
Non-Linear Rituximab Pharmacokinetics and Complex Relationship between Rituximab Concentrations and Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in ANCA-Associated Vasculitis: The RAVE Trial Revisited
(2019). Clin Pharmacokinet., epub ahead of print. http://dx.doi.org/10.1007/s40262-019-00826-5, PMID: 31586310
Bensalem A, Mulleman D, Paintaud G, Azzopardi N, Gouilleux-Gruart V, Cornec D, Specks U, Ternant D
[PubMed]
[Citation View]
Bensalem A, Mulleman D, Paintaud G, Azzopardi N, Gouilleux-Gruart V, Cornec D, Specks U, Ternant D (2019). Non-Linear Rituximab Pharmacokinetics and Complex Relationship between Rituximab Concentrations and Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in ANCA-Associated Vasculitis: The RAVE Trial Revisited. Clin Pharmacokinet., epub ahead of print.
T-cell exhaustion correlates with improved outcomes in kidney transplant recipients
(2019). Kidney Int, 96 (2), 436-449. http://dx.doi.org/10.1016/j.kint.2019.01.040, PMID: 31040060, PMCID: PMC6650324
Fribourg M, Anderson L, Fischman C, Cantarelli C, Perin L, La Manna G, Rahman A, Burrell BE, Heeger PS, Cravedi P
[PubMed]
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Fribourg M, Anderson L, Fischman C, Cantarelli C, Perin L, La Manna G, Rahman A, Burrell BE, Heeger PS, Cravedi P (2019). T-cell exhaustion correlates with improved outcomes in kidney transplant recipients. Kidney Int, 96 (2), 436-449.
IgG4 donor-specific HLA antibody profile is associated with subclinical rejection in stable pediatric liver recipients
(2019). Am J Transplant, epub ahead of print. http://dx.doi.org/10.1111/ajt.15621, PMID: 31561279
Jackson AM, Kanaparthi S, Burrell BE, Lucas DP, Vega RM, Demetris AJ, Feng S
[PubMed]
[Citation View]
Jackson AM, Kanaparthi S, Burrell BE, Lucas DP, Vega RM, Demetris AJ, Feng S (2019). IgG4 donor-specific HLA antibody profile is associated with subclinical rejection in stable pediatric liver recipients. Am J Transplant, epub ahead of print.
A composite immune signature parallels disease progression across T1D subjects
(2019). JCI Insight, 4 (23), 126917. http://dx.doi.org/10.1172/jci.insight.126917, PMID: 31671072
Speake C, Skinner SO, Berel D, Whalen E, Dufort MJ, Young WC, Odegard JM, Pesenacker AM, Gorus FK, James E, Levings MK, Linsley PS, Akirav EM, Pugliese A, Hessner MJ, Nepom GT, Gottardo R, Long SA
[Reprint] [PubMed]
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Speake C, Skinner SO, Berel D, Whalen E, Dufort MJ, Young WC, Odegard JM, Pesenacker AM, Gorus FK, James E, Levings MK, Linsley PS, Akirav EM, Pugliese A, Hessner MJ, Nepom GT, Gottardo R, Long SA (2019). A composite immune signature parallels disease progression across T1D subjects. JCI Insight, 4 (23), 126917.
Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression
(2019). J Clin Invest, epub ahead of print. http://dx.doi.org/10.1172/JCI126595, PMID: 31815738
Wiedeman AE, Muir VS, Rosasco M, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James E, Linsley PS, Long SA
[Reprint] [PubMed]
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Wiedeman AE, Muir VS, Rosasco M, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James E, Linsley PS, Long SA (2019). Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression. J Clin Invest, epub ahead of print.
Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis
(2019). JCI Insight, epub ahead of print. http://dx.doi.org/10.1172/jci.insight.127655, PMID: 31877116
Harris KM, Lim N, Lindau P, Robins H, Griffith LM, Nash RA, Turka LA, Muraro PA
[Reprint] [PubMed]
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Harris KM, Lim N, Lindau P, Robins H, Griffith LM, Nash RA, Turka LA, Muraro PA (2019). Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis. JCI Insight, epub ahead of print.
Alpha‐1 antitrypsin treatment of new‐onset type 1 diabetes: an open‐label, phase I clinical trial (RETAIN) to assess safety and pharmacokinetics
(2018). Pediatr Diabetes., E published ahead of print. http://dx.doi.org/10.1111/pedi.12660, PMID: 29473705
Weir GC, Ehlers MR, Harris KM, Kanaparthi S, Long A, Phippard D, Weiner LJ, Jepson B, McNamara JG, Koulmanda M, Strom TB, ITN RETAIN Study Team
[Reprint] [PubMed]
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Weir GC, Ehlers MR, Harris KM, Kanaparthi S, Long A, Phippard D, Weiner LJ, Jepson B, McNamara JG, Koulmanda M, Strom TB, ITN RETAIN Study Team (2018). Alpha‐1 antitrypsin treatment of new‐onset type 1 diabetes: an open‐label, phase I clinical trial (RETAIN) to assess safety and pharmacokinetics. Pediatr Diabetes., E published ahead of print.
Evidence of Chronic Allograft Injury in Liver Biopsies From Long-term Pediatric Recipients of Liver Transplants
(2018). Gastroenterology, E published ahead of print. http://dx.doi.org/10.1053/j.gastro.2018.08.023, PMID: 30144432
Feng S, Bucuvalas JC, Demetris AJ, Burrell BE, Spain KM, Kanaparthi S, Magee JC, Ikle D, Lesniak A, Lozano JJ, Alonso EM, Bray RA, Bridges NE, Doo E, Gebel HM, Gupta NA, Himes RW, Jackson AM, Lobritto SJ, Mazariegos GV, Ng VL, Rand EB, Sherker AH, Sundaram S, Turmelle YP, Sanchez-Fueyo A
[Reprint] [PubMed]
[Citation View]
Feng S, Bucuvalas JC, Demetris AJ, Burrell BE, Spain KM, Kanaparthi S, Magee JC, Ikle D, Lesniak A, Lozano JJ, Alonso EM, Bray RA, Bridges NE, Doo E, Gebel HM, Gupta NA, Himes RW, Jackson AM, Lobritto SJ, Mazariegos GV, Ng VL, Rand EB, Sherker AH, Sundaram S, Turmelle YP, Sanchez-Fueyo A (2018). Evidence of Chronic Allograft Injury in Liver Biopsies From Long-term Pediatric Recipients of Liver Transplants. Gastroenterology, E published ahead of print.
Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables
(2018). Diabetologia, Epub ahead of print, 1-8. http://dx.doi.org/10.1007/s00125-018-4722-z, PMID: 30167735
John M. Wentworth, Naiara G. Bediaga, Lynne C. Giles, Mario Ehlers, Stephen E. Gitelman, Susan Geyer, Carmella Evans-Molina, Leonard C. Harrison, the Type 1 Diabetes TrialNet Study Group, the Immune Tolerance Network Study Group
[Reprint] [PubMed]
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John M. Wentworth, Naiara G. Bediaga, Lynne C. Giles, Mario Ehlers, Stephen E. Gitelman, Susan Geyer, Carmella Evans-Molina, Leonard C. Harrison, the Type 1 Diabetes TrialNet Study Group, the Immune Tolerance Network Study Group (2018). Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables. Diabetologia, Epub ahead of print, 1-8.
A novel human mast cell activation test for peanut allergy
(2018). J Allergy Clin Immunol, 142 (2), 689-691. http://dx.doi.org/10.1016/j.jaci.2018.03.011, PMID: 29731128, PMCID: PMC6080741
Santos AF, Couto-Francisco N, Becares N, Kwok M, Bahnson HT, Lack G
[Reprint] [PubMed]
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Santos AF, Couto-Francisco N, Becares N, Kwok M, Bahnson HT, Lack G (2018). A novel human mast cell activation test for peanut allergy. J Allergy Clin Immunol, 142 (2), 689-691.
Challenges and Opportunities for Biomarkers of Clinical Response to AHSCT in Autoimmunity
(2018). Front Immunol, 9, 100. http://dx.doi.org/10.3389/fimmu.2018.00100, PMID: 29456529, PMCID: PMC5801415
Harris KM, Lu T, Lim N, Turka LA
[Reprint] [PubMed]
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Harris KM, Lu T, Lim N, Turka LA (2018). Challenges and Opportunities for Biomarkers of Clinical Response to AHSCT in Autoimmunity. Front Immunol, 9, 100.
Early expansion of donor-specific Tregs in tolerant kidney transplant recipients
(2018). JCI Insight, 3 (22). http://dx.doi.org/10.1172/jci.insight.124086, PMID: 30429370
Savage TM, Shonts BA, Obradovic A, DeWolf S, Lau S, Zuber J, Simpson MT, Berglund E, Fu J, Yang S, Ho S, Tang Q, Turka LA, Shen Y, Sykes M
[Reprint] [PubMed]
[Citation View]
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Treatment of type 1 diabetes with teplizumab: clinical and immunological follow-up after 7 years from diagnosis.
(2018). Diabetologia, Epub ahead of print, 1-10. http://dx.doi.org/10.1007/s00125-018-4786-9, PMID: 30569273
Perdigoto AL, Preston-Hurlburt P, Clark P, Long SA, Linsley PS, Harris KM, Gitelman SE, Greenbaum CJ, Gottlieb PA, Hagopian W, Woodwyk A, Dziura J, Herold K
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FRI0305 Phase 2 trial of induction therapy with anti-cd20 (RITUXIMAB) followed by maintenance therapy with anti-baff (BELIMUMAB) in patients with active lupus nephritis
(2018). Ann Rheum Dis, 690. http://dx.doi.org/10.1136/annrheumdis-2018-eular.5711
Aranow C, Dall'Era M, Byron M, Ding L, Smilek D, Diamond B, Wofsy D
Aranow C, Dall'Era M, Byron M, Ding L, Smilek D, Diamond B, Wofsy D (2018). FRI0305 Phase 2 trial of induction therapy with anti-cd20 (RITUXIMAB) followed by maintenance therapy with anti-baff (BELIMUMAB) in patients with active lupus nephritis. Ann Rheum Dis, 690.
Five year histological and serological follow-up of operationally tolerant pediatric liver transplant recipients enrolled in WISP-R
(2017). Hepatology, 65 (2), 647-60. http://dx.doi.org/10.1002/hep.28681, PMID: 27302659, PMCID: PMC5159322
Feng S, Demetris AJ, Kanaparthi S, Ekong UD, Alonso EM, Rosenthal P, Turka LA, Ikle D, Tchao NK, Spain KM, Burrell BE
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Feng S, Demetris AJ, Kanaparthi S, Ekong UD, Alonso EM, Rosenthal P, Turka LA, Ikle D, Tchao NK, Spain KM, Burrell BE (2017). Five year histological and serological follow-up of operationally tolerant pediatric liver transplant recipients enrolled in WISP-R. Hepatology, 65 (2), 647-60.
ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis
(2017). Mult Scler. http://dx.doi.org/10.1177/1352458516662727, PMID: 27481207, PMCID: PMC5288398
Khoury SJ, Ding L, Gao W, Arnold DL, Sayre PH, Smilek DE, Rochon J, Byron M, Ryker K, Tosta P, Freedman MS, ACCLAIM Study Group
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Khoury SJ, Ding L, Gao W, Arnold DL, Sayre PH, Smilek DE, Rochon J, Byron M, Ryker K, Tosta P, Freedman MS, ACCLAIM Study Group (2017). ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis. Mult Scler.
Effect of Disease Activity, Glucocorticoid Exposure, and Rituximab Determine Body Composition Changes during Induction Treatment of ANCA-Associated Vasculitis
(2017). Arthritis Care Res (Hoboken)., 69 (7), 1001-10. http://dx.doi.org/10.1002/acr.23099, PMID: 27696762, PMCID: PMC5611860
Wallace ZS, Miloslavsky EM, Cascino M, Unizony SH, Lu N, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera R, St Clair EW, Specks U, Brunetta P, Choi HK, Stone JH
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Wallace ZS, Miloslavsky EM, Cascino M, Unizony SH, Lu N, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera R, St Clair EW, Specks U, Brunetta P, Choi HK, Stone JH (2017). Effect of Disease Activity, Glucocorticoid Exposure, and Rituximab Determine Body Composition Changes during Induction Treatment of ANCA-Associated Vasculitis. Arthritis Care Res (Hoboken)., 69 (7), 1001-10.
An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection
(2017). Hepatology, 65 (1), 269-80. http://dx.doi.org/10.1002/hep.28786, PMID: 27533743
Shaked A, Sayre P, Li YR, Asare S, DesMarais M, Holmes MV, Guettouche T, Keating BJ, Chang BL, Barnes MR
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Shaked A, Sayre P, Li YR, Asare S, DesMarais M, Holmes MV, Guettouche T, Keating BJ, Chang BL, Barnes MR (2017). An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection. Hepatology, 65 (1), 269-80.
The pharmacogenomic association of Fcγ receptors and cytochrome p450 enzymes and response to treatment with rituximab or cyclophosphamide in Anti-Neutrophil Cytoplasmic Antibody-Associated vasculitis
(2017). Arthritis Rheumatol, 69 (1), 169-75. http://dx.doi.org/10.1002/art.39822, PMID: 27482943
Cartin-ceba R, Indrakanti D, Specks U, Stone JH, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Spiera RF, Monach PA, Seo P, Tchao NK, Ytterberg SR, St Clair W, Brunetta PG, Song H, Birmingham D, Rovin BH; RAVE-ITN Research Group
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Cartin-ceba R, Indrakanti D, Specks U, Stone JH, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Spiera RF, Monach PA, Seo P, Tchao NK, Ytterberg SR, St Clair W, Brunetta PG, Song H, Birmingham D, Rovin BH; RAVE-ITN Research Group (2017). The pharmacogenomic association of Fcγ receptors and cytochrome p450 enzymes and response to treatment with rituximab or cyclophosphamide in Anti-Neutrophil Cytoplasmic Antibody-Associated vasculitis. Arthritis Rheumatol, 69 (1), 169-75.
Association of serum calprotectin (S100A8/S100A9) levels with disease relapses in PR3-ANCA-associated vasculitis
(2017). Arthritis Rheumatol, 69 (1), 185-93. http://dx.doi.org/10.1002/art.39814, PMID: 27428710
Pepper RJ, Draibe JB, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Monach PA, Seo P, Spiera R, St Clair EW, Tchao NK, Stone JH, Specks U, Merkel PA, Caplin B, Salama AD; RAVE-ITN Research Group
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Pepper RJ, Draibe JB, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Monach PA, Seo P, Spiera R, St Clair EW, Tchao NK, Stone JH, Specks U, Merkel PA, Caplin B, Salama AD; RAVE-ITN Research Group (2017). Association of serum calprotectin (S100A8/S100A9) levels with disease relapses in PR3-ANCA-associated vasculitis. Arthritis Rheumatol, 69 (1), 185-93.
Clinical outcomes of treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis based on ANCA type
(2017). Ann Rheum Dis, 75 (6), 1166-9. http://dx.doi.org/10.1136/annrheumdis-2015-208073, PMID: 26621483, PMCID: PMC4908815
Unizony S, Miloslavsky EM, Lu N, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, St Clair EW, Ikle D, Tchao NK, Ding L, Brunetta P, Monach PA, Fervenza F, Stone JH, Specks U; RAVE-ITN Research Group, Villarreal M, Kallenberg CM, Choi HK1
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Unizony S, Miloslavsky EM, Lu N, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, St Clair EW, Ikle D, Tchao NK, Ding L, Brunetta P, Monach PA, Fervenza F, Stone JH, Specks U; RAVE-ITN Research Group, Villarreal M, Kallenberg CM, Choi HK1 (2017). Clinical outcomes of treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis based on ANCA type. Ann Rheum Dis, 75 (6), 1166-9.
Effect of 2 Years of Treatment With Sublingual Grass Pollen Immunotherapy on Nasal Response to Allergen Challenge at 3 Years Among Patients With Moderate to Severe Seasonal Allergic Rhinitis: The GRASS Randomized Clinical Trial
(2017). JAMA, 317 (6), 615-625. http://dx.doi.org/10.1001/jama.2016.21040, PMID: 28196255
Scadding GW, Calderon MA, Shamji MH, Eifan AO, Penagos M, Sever ML, Bahnson HT, Lawson K, Harris KM, Lim N, Tchao NK, Togias A, Dumitru F, Plough AG, Panza JL, Qin T, Durham SR; Immune Tolerance Network GRASS Study Team
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Scadding GW, Calderon MA, Shamji MH, Eifan AO, Penagos M, Sever ML, Bahnson HT, Lawson K, Harris KM, Lim N, Tchao NK, Togias A, Dumitru F, Plough AG, Panza JL, Qin T, Durham SR; Immune Tolerance Network GRASS Study Team (2017). Effect of 2 Years of Treatment With Sublingual Grass Pollen Immunotherapy on Nasal Response to Allergen Challenge at 3 Years Among Patients With Moderate to Severe Seasonal Allergic Rhinitis: The GRASS Randomized Clinical Trial. JAMA, 317 (6), 615-625.
Anti-Gal and anti-Neu5Gc responses in nonimmunosuppressed patients following treatment with rabbit anti-thymocyte polyclonal IgGs
(2017). Transplantation, 101 (10), 2501-07. http://dx.doi.org/10.1097/TP.0000000000001686, PMID: 28198767
Lim N, Brouard S, Harris KM, Ehlers MR, Gitelman SE, Soulillou JP, Salama A1, Evanno G, Rousse J, Le Berre L, Nicot A
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Lim N, Brouard S, Harris KM, Ehlers MR, Gitelman SE, Soulillou JP, Salama A1, Evanno G, Rousse J, Le Berre L, Nicot A (2017). Anti-Gal and anti-Neu5Gc responses in nonimmunosuppressed patients following treatment with rabbit anti-thymocyte polyclonal IgGs. Transplantation, 101 (10), 2501-07.
High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS
(2017). Neurology, Feb 1 2017. http://dx.doi.org/10.1212/WNL.0000000000003660, PMID: 28148635, PMCID: PMC5331868
Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stüve O, Arnold DL, Georges GE, Wundes A, Kraft GH, Bowen JD, Steinmiller KC, Wener MH
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Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stüve O, Arnold DL, Georges GE, Wundes A, Kraft GH, Bowen JD, Steinmiller KC, Wener MH (2017). High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS. Neurology, Feb 1 2017.
Immunoglobulin (Ig)M antibodies to proteinase 3 in granulomatosis with polyangiitis and microscopic polyangiitis
(2017). Clin Exp Immunol, 188 (1), 174-81. http://dx.doi.org/0.1111/cei.12925, PMID: 28076879, PMCID: PMC5343341
Clain JM, Hummel AM, Stone JH, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, McCune WJ, Specks U; WGET and RAVE-ITN Research Groups
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Clain JM, Hummel AM, Stone JH, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, McCune WJ, Specks U; WGET and RAVE-ITN Research Groups (2017). Immunoglobulin (Ig)M antibodies to proteinase 3 in granulomatosis with polyangiitis and microscopic polyangiitis. Clin Exp Immunol, 188 (1), 174-81.
B Cell Receptor Genes Associated with Tolerance Identify a Cohort of Immunosuppressed Patients with Improved Renal Allograft Graft Function
(2017). Am J Transplant. http://dx.doi.org/10.1111/ajt.14283, PMID: 28371372, PMCID: PMC5620117
Asare A, Kanaparthi S, Lim N, Phippard D, Burrell BE, Bridges N, Sanz I, Newell KA, Turka LA, Vincenti F, Friedewald J, Pavlakis M, Poggio E, Heeger P, Mannon R, Morrison Y, Chandraker A
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Asare A, Kanaparthi S, Lim N, Phippard D, Burrell BE, Bridges N, Sanz I, Newell KA, Turka LA, Vincenti F, Friedewald J, Pavlakis M, Poggio E, Heeger P, Mannon R, Morrison Y, Chandraker A (2017). B Cell Receptor Genes Associated with Tolerance Identify a Cohort of Immunosuppressed Patients with Improved Renal Allograft Graft Function. Am J Transplant.
Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance
(2017). Am J Transplant. http://dx.doi.org/10.1111/ajt.14251, PMID: 28251801, PMCID: PMC5519438
Sprangers B, DeWolf S, Morokata T, LoCascio SA, Shonts B, Zuber J, Morris H, Zorn E, Preffer FI, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M, Savage TM, Obradovic A, Lau SP, Shah R, Steshenko V, Olek S
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Sprangers B, DeWolf S, Morokata T, LoCascio SA, Shonts B, Zuber J, Morris H, Zorn E, Preffer FI, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M, Savage TM, Obradovic A, Lau SP, Shah R, Steshenko V, Olek S (2017). Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance. Am J Transplant.