Publications
Articles
A CD8 + NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis
(2021). Nat Commun, 12 (1), 635. http://dx.doi.org/10.1038/s41467-020-20594-2, PMID: 33504809, PMCID: PMC7840761
McKinney EF, Cuthbertson I, Harris KM, Smilek D, Connor C, Manferrari G, Carr EJ, Zamvil SS, Smith KGC
[PubMed]
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McKinney EF, Cuthbertson I, Harris KM, Smilek D, Connor C, Manferrari G, Carr EJ, Zamvil SS, Smith KGC (2021). A CD8 + NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis. Nat Commun, 12 (1), 635.
Differential Induction of Allergen-specific IgA Responses following Timothy Grass Subcutaneous and Sublingual Immunotherapy
(2021). J Allergy Clin Immunol, S0091-6749 (21), 00552-2. http://dx.doi.org/10.1016/j.jaci.2021.03.030, PMID: 33819508
Shamji MH, Larson D, Eifan A, Scadding GW, Qin T, Lawson K, Sever ML, Macfarlane Ellen, Layhadi JA, Wurtzen PA, Parkin RV, Sanda S, Harris KM, Nepom GT, Togias A, Durham SR
[Reprint] [PubMed]
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Shamji MH, Larson D, Eifan A, Scadding GW, Qin T, Lawson K, Sever ML, Macfarlane Ellen, Layhadi JA, Wurtzen PA, Parkin RV, Sanda S, Harris KM, Nepom GT, Togias A, Durham SR (2021). Differential Induction of Allergen-specific IgA Responses following Timothy Grass Subcutaneous and Sublingual Immunotherapy. J Allergy Clin Immunol, S0091-6749 (21), 00552-2.
Non-Linear Rituximab Pharmacokinetics and Complex Relationship between Rituximab Concentrations and Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in ANCA-Associated Vasculitis: The RAVE Trial Revisited
(2020). Clin Pharmacokinet., 59 (4), 519-530. http://dx.doi.org/10.1007/s40262-019-00826-5, PMID: 31586310
Bensalem A, Mulleman D, Paintaud G, Azzopardi N, Gouilleux-Gruart V, Cornec D, Specks U, Ternant D
[PubMed]
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Bensalem A, Mulleman D, Paintaud G, Azzopardi N, Gouilleux-Gruart V, Cornec D, Specks U, Ternant D (2020). Non-Linear Rituximab Pharmacokinetics and Complex Relationship between Rituximab Concentrations and Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in ANCA-Associated Vasculitis: The RAVE Trial Revisited. Clin Pharmacokinet., 59 (4), 519-530.
Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression
(2020). J Clin Invest, 130 (1), 480-490. http://dx.doi.org/10.1172/JCI126595, PMID: 31815738, PMCID: PMC6934185
Wiedeman AE, Muir VS, Rosasco M, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James E, Linsley PS, Long SA
[Reprint] [PubMed]
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Wiedeman AE, Muir VS, Rosasco M, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James E, Linsley PS, Long SA (2020). Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression. J Clin Invest, 130 (1), 480-490.
Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes
(2020). Nat Immunol, 21 (5), 578-587. http://dx.doi.org/10.1038/s41590-020-0633-5, PMID: 32231298, PMCID: PMC7183435
Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Chase Crawford J, Alfei F, Alli S, Pereira Ribeiro S, Castellaw AH, McGargill MA, Jin H, Boi SH, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly R, Zehn D, James E, Nepom GT, Youngblood B
[Reprint] [PubMed]
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Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Chase Crawford J, Alfei F, Alli S, Pereira Ribeiro S, Castellaw AH, McGargill MA, Jin H, Boi SH, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly R, Zehn D, James E, Nepom GT, Youngblood B (2020). Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nat Immunol, 21 (5), 578-587.
Nasal Allergen Challenge and Environmental Exposure Chamber Challenge: A Randomized Trial Comparing Clinical and Biological Responses to Cat Allergen
(2020). J Allergy Clin Immunol, 145 (6), 1585-1597. http://dx.doi.org/10.1016/j.jaci.2020.02.024, PMID: 32169380
Larson D, Patel P, Salapatek AM, Couroux P, Whitehouse D, Pina A, Johnson JL, Sever ML, Sanda S, Poyser J, Allio T, Scadding GW, Qin T, Shamji MH, Kwok WW, James E, French D, Lelic A, Larché M, Altman MC, Togias A, Durham SR
[Reprint] [PubMed]
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Larson D, Patel P, Salapatek AM, Couroux P, Whitehouse D, Pina A, Johnson JL, Sever ML, Sanda S, Poyser J, Allio T, Scadding GW, Qin T, Shamji MH, Kwok WW, James E, French D, Lelic A, Larché M, Altman MC, Togias A, Durham SR (2020). Nasal Allergen Challenge and Environmental Exposure Chamber Challenge: A Randomized Trial Comparing Clinical and Biological Responses to Cat Allergen. J Allergy Clin Immunol, 145 (6), 1585-1597.
Association of Respiratory Allergy, Asthma and Expression of the SARS-CoV-2 Receptor, ACE2
(2020). J Allergy Clin Immunol, epub ahead of print. http://dx.doi.org/10.1016/j.jaci.2020.04.009, PMID: 32333915, PMCID: PMC7175851
Jackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, Ober C, Gergen PJ, Becker P, Togias A, Gern JE, Altman MC
[Reprint] [PubMed]
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Jackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, Ober C, Gergen PJ, Becker P, Togias A, Gern JE, Altman MC (2020). Association of Respiratory Allergy, Asthma and Expression of the SARS-CoV-2 Receptor, ACE2. J Allergy Clin Immunol, epub ahead of print.
CALIBRATE: A Phase 2 Randomized Trial of Rituximab Plus Cyclophosphamide Followed by Belimumab for the Treatment of Lupus Nephritis
(2020). Arthritis Rheumatol., 73 (1), 121-131. http://dx.doi.org/10.1002/art.41466, PMID: 32755035, PMCID: PMC7839443
Atisha-Fregoso Y, Malkiel S, Harris KM, Byron M, Ding L, Kanaparthi S, Barry WT, Gao W, Ryker K, Tosta P, Askanase AD, Boackle SA, Chatham WW, Kamen DL, Karp DR, Kirou KA, Lim SS, Marder B, McMahon M, Parikh SV, Pendergraft WF 3rd, Podoll AS, Saxena A, Wofsy D, Diamond B, Smilek DE, Aranow C, Dall'Era M
[Reprint] [PubMed]
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Atisha-Fregoso Y, Malkiel S, Harris KM, Byron M, Ding L, Kanaparthi S, Barry WT, Gao W, Ryker K, Tosta P, Askanase AD, Boackle SA, Chatham WW, Kamen DL, Karp DR, Kirou KA, Lim SS, Marder B, McMahon M, Parikh SV, Pendergraft WF 3rd, Podoll AS, Saxena A, Wofsy D, Diamond B, Smilek DE, Aranow C, Dall'Era M (2020). CALIBRATE: A Phase 2 Randomized Trial of Rituximab Plus Cyclophosphamide Followed by Belimumab for the Treatment of Lupus Nephritis. Arthritis Rheumatol., 73 (1), 121-131.
Precision transplant pathology
(2020). Curr Opin Organ Transplant, 25 (4), 412-419. http://dx.doi.org/10.1097/MOT.0000000000000772, PMID: 32520786, PMCID: PMC7737245
Wood-Trageser MA, Xu Q, Zeevi A, Randhawa P, Lesniak A, Demetris AJ
[PubMed]
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Wood-Trageser MA, Xu Q, Zeevi A, Randhawa P, Lesniak A, Demetris AJ (2020). Precision transplant pathology. Curr Opin Organ Transplant, 25 (4), 412-419.
Biomarkers of severity and threshold of allergic reactions during oral peanut challenges
(2020). J Allergy Clin Immunol, 146 (2), 344-355. http://dx.doi.org/10.1016/j.jaci.2020.03.035, PMID: 32311390, PMCID: PMC7417812
Santos AF, Du Toit G, O'Rourke C, Becares N, Couto-Francisco N, Radulovic S, Khaleva Ekaterina, Basting M, Harris KM, Larson D, Sayre P, Plaut M, Roberts G, Bahnson HT, Lack G
[PubMed]
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Santos AF, Du Toit G, O'Rourke C, Becares N, Couto-Francisco N, Radulovic S, Khaleva Ekaterina, Basting M, Harris KM, Larson D, Sayre P, Plaut M, Roberts G, Bahnson HT, Lack G (2020). Biomarkers of severity and threshold of allergic reactions during oral peanut challenges. J Allergy Clin Immunol, 146 (2), 344-355.
Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis
(2020). JCI Insight, 5 (2), e127655. http://dx.doi.org/10.1172/jci.insight.127655, PMID: 31877116, PMCID: PMC7098711
Harris KM, Lim N, Lindau P, Robins H, Griffith LM, Nash RA, Turka LA, Muraro PA
[Reprint] [PubMed]
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Harris KM, Lim N, Lindau P, Robins H, Griffith LM, Nash RA, Turka LA, Muraro PA (2020). Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis. JCI Insight, 5 (2), e127655.
Stem, effector and hybrid states of memory CD8+ T cells
(2020). Trends Immunol., 41 (1), 17-28. http://dx.doi.org/10.1016/j.it.2019.11.004., PMID: 31810790, PMCID: PMC6934921
Lugli E, Galletti G, Boi SK, Youngblood B
[Reprint] [PubMed]
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Lugli E, Galletti G, Boi SK, Youngblood B (2020). Stem, effector and hybrid states of memory CD8+ T cells. Trends Immunol., 41 (1), 17-28.
Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3 in ANCA-Associated Vasculitis
(2020). Front Immunol, 11, 2053. http://dx.doi.org/10.3389/fimmu.2020.02053, PMID: 33013868, PMCID: PMC7495134
Thompson GE, Fussner LA, Hummel AM, Schroeder DR, Silva F, Snyder MR, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Stone JH, Specks U
[Reprint] [PubMed]
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Thompson GE, Fussner LA, Hummel AM, Schroeder DR, Silva F, Snyder MR, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Stone JH, Specks U (2020). Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3 in ANCA-Associated Vasculitis. Front Immunol, 11, 2053.
Deletion of donor-reactive T cell clones after human liver transplant
(2020). Am J Transplant, 20 (2), 538-545. http://dx.doi.org/10.1111/ajt.15592, PMID: 31509321, PMCID: PMC6984984
Savage TM, Shonts BA, Lau S, Obradovic A, Robins H, Shaked A, Shen Y, Sykes M
[Reprint] [PubMed]
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Savage TM, Shonts BA, Lau S, Obradovic A, Robins H, Shaked A, Shen Y, Sykes M (2020). Deletion of donor-reactive T cell clones after human liver transplant. Am J Transplant, 20 (2), 538-545.
Medical algorithm: Early introduction of food allergens in high-risk Populations
(2020). Allergy, epub ahead of print. http://dx.doi.org/10.1111/all.14717, PMID: 33346913
Fisher HR, Lack G, Roberts G, Bahnson HT, Du Toit G
[PubMed]
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Fisher HR, Lack G, Roberts G, Bahnson HT, Du Toit G (2020). Medical algorithm: Early introduction of food allergens in high-risk Populations. Allergy, epub ahead of print.
Pediatric Allergic Diseases, Food Allergy, and Oral Tolerance
(2020). Annu Rev Cell Dev Biol, 36, 511-528. http://dx.doi.org/10.1146/annurev-cellbio-100818-125346, PMID: 32634325
Logan K, Du Toit G, Giovannini M, Turcanu V, Lack G
[PubMed]
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Logan K, Du Toit G, Giovannini M, Turcanu V, Lack G (2020). Pediatric Allergic Diseases, Food Allergy, and Oral Tolerance. Annu Rev Cell Dev Biol, 36, 511-528.
Epicutaneous sensitization in the development of food allergy: What is the evidence and how can this be prevented?
(2020). Allergy, 75 (9), 2185-2205. http://dx.doi.org/10.1111/all.14304, PMID: 32249942, PMCID: PMC7494573
Brough HA, Nadeau KC, Sindher SB, Alkotob SS, Chan S, Bahnson HT, Leung DYM, Lack G
[PubMed]
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Brough HA, Nadeau KC, Sindher SB, Alkotob SS, Chan S, Bahnson HT, Leung DYM, Lack G (2020). Epicutaneous sensitization in the development of food allergy: What is the evidence and how can this be prevented?. Allergy, 75 (9), 2185-2205.
IgE to epitopes of Ara h 2 enhance the diagnostic accuracy of Ara h 2-specific IgE
(2020). Allergy, 75 (9), 2309-2318. http://dx.doi.org/10.1111/all.14301, PMID: 32248566
Santos AF, Barbosa-Morais NL, Hurlburt BK, Ramaswamy S, Hemmings O, Kwok M, O'Rourke C, Bahnson HT, Cheng H, James L, Gould HJ, Sutton BJ, Maleki SJ, Lack G
[PubMed]
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Santos AF, Barbosa-Morais NL, Hurlburt BK, Ramaswamy S, Hemmings O, Kwok M, O'Rourke C, Bahnson HT, Cheng H, James L, Gould HJ, Sutton BJ, Maleki SJ, Lack G (2020). IgE to epitopes of Ara h 2 enhance the diagnostic accuracy of Ara h 2-specific IgE. Allergy, 75 (9), 2309-2318.
Fc receptor-like 5 and anti-CD20 treatment response in granulomatosis with polyangiitis and microscopic polyangiitis
(2020). JCI Insight, 5 (18), e136180. http://dx.doi.org/10.1172/jci.insight.136180, PMID: 32841219, PMCID: PMC7526555
Owczarczyk K, Cascino M, Holweg C, Tew GW, Ortmann W, Behrens T, Schindler T, Langford CA, St Clair EW, Merkel PA, Spiera R, Seo P, Kallenberg CG, Specks U, Lim N, Stone J, Brunetta P, Prunotto M, RAVE-ITN Research Group
[Reprint] [PubMed]
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Owczarczyk K, Cascino M, Holweg C, Tew GW, Ortmann W, Behrens T, Schindler T, Langford CA, St Clair EW, Merkel PA, Spiera R, Seo P, Kallenberg CG, Specks U, Lim N, Stone J, Brunetta P, Prunotto M, RAVE-ITN Research Group (2020). Fc receptor-like 5 and anti-CD20 treatment response in granulomatosis with polyangiitis and microscopic polyangiitis. JCI Insight, 5 (18), e136180.
Efficacy and Safety of Immunosuppression Withdrawal in Pediatric Liver Transplant Recipients: Moving Towards Personalized Management
(2020). Hepatology, epub ahead of print. http://dx.doi.org/10.1002/hep.31520, PMID: 32786149
Feng S, Bucuvalas JC, Mazariegos GV, Magee JC, Sanchez-Fueyo A, Spain KM, Lesniak A, Kanaparthi S, Perito ER, Venkat V, Burrell BE, Alonso EM, Bridges ND, Doo E, Gupta NA, Himes RW, Ikle D, Jackson AM, Lobritto SJ, Jose Lozano J, Martinez M, Ng VL, Rand EB, Sherker AH, Sundaram S, Turmelle YP, Wood-Trageser MA, Demetris AJ
[PubMed]
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Feng S, Bucuvalas JC, Mazariegos GV, Magee JC, Sanchez-Fueyo A, Spain KM, Lesniak A, Kanaparthi S, Perito ER, Venkat V, Burrell BE, Alonso EM, Bridges ND, Doo E, Gupta NA, Himes RW, Ikle D, Jackson AM, Lobritto SJ, Jose Lozano J, Martinez M, Ng VL, Rand EB, Sherker AH, Sundaram S, Turmelle YP, Wood-Trageser MA, Demetris AJ (2020). Efficacy and Safety of Immunosuppression Withdrawal in Pediatric Liver Transplant Recipients: Moving Towards Personalized Management. Hepatology, epub ahead of print.
Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus
(2020). Hepatology, 72 (2), 569-583. http://dx.doi.org/10.1002/hep.31036, PMID: 31721246, PMCID: PMC7217743
Levitsky J, Burrell BE, Kanaparthi S, Turka LA, Kurian SM, Sanchez-Fueyo A, Lozano JJ, Demetris A, Lesniak A, Kirk AD, Stempora L, Yang G, Mathew JM
[PubMed]
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Levitsky J, Burrell BE, Kanaparthi S, Turka LA, Kurian SM, Sanchez-Fueyo A, Lozano JJ, Demetris A, Lesniak A, Kirk AD, Stempora L, Yang G, Mathew JM (2020). Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus. Hepatology, 72 (2), 569-583.
Exhausted-like CD8 T cell phenotypes linked to C-peptide preservation in alefacept-treated T1D subjects
(2020). JCI Insight, epub ahead of print, 142680. http://dx.doi.org/10.1172/jci.insight.142680, PMID: 33351781
Diggins KE, Serti E, Muir VS, Rosasco M, Lu T, Balmas E, Nepom GT, Linsley PS
[Reprint] [PubMed]
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Diggins KE, Serti E, Muir VS, Rosasco M, Lu T, Balmas E, Nepom GT, Linsley PS (2020). Exhausted-like CD8 T cell phenotypes linked to C-peptide preservation in alefacept-treated T1D subjects. JCI Insight, epub ahead of print, 142680.
CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes
(2020). JCI Insight, 6 (2), e136114. http://dx.doi.org/10.1172/jci.insight.136114, PMID: 33301420
Narsale A, Lam B, Moya R, Lu T, Mandelli A, Gotuzzo I, Pessina B, Giamporcaro G, Geoffrey R, Buchanan K, Harris M, Bergot A, Thomas R, Hessner MJ, Battaglia M, Serti E, Davies JD
[Reprint] [PubMed]
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Narsale A, Lam B, Moya R, Lu T, Mandelli A, Gotuzzo I, Pessina B, Giamporcaro G, Geoffrey R, Buchanan K, Harris M, Bergot A, Thomas R, Hessner MJ, Battaglia M, Serti E, Davies JD (2020). CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes. JCI Insight, 6 (2), e136114.
Post-transplant biopsy risk for stable long-term pediatric liver transplant recipients: 451 percutaneous biopsies from two multi-center immunosuppression withdrawal trials
(2019). Am J Transplant. http://dx.doi.org/10.1111/ajt.15255, PMID: 30614623
Perito ER, Martinez M, Turmelle YP, Mason K, Spain KM, Bucuvalas JC, Feng S
[PubMed]
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Perito ER, Martinez M, Turmelle YP, Mason K, Spain KM, Bucuvalas JC, Feng S (2019). Post-transplant biopsy risk for stable long-term pediatric liver transplant recipients: 451 percutaneous biopsies from two multi-center immunosuppression withdrawal trials. Am J Transplant.
Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance
(2019). J Immunol, e pub. http://dx.doi.org/10.4049/jimmunol.1801425, PMID: 30683697
Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E
[Reprint] [PubMed]
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Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E (2019). Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance. J Immunol, e pub.
Outcomes of immunosuppression minimization and withdrawal early after liver transplantation
(2019). Am J Transplant, 19 (5), 1397‐1409. http://dx.doi.org/10.1111/ajt.15205, PMID: 30506630, PMCID: PMC6482056
Shaked A, DesMarais MR, Kopetskie H, Feng S, Punch J, Levitsky J, Reyes J, Klintmalm G, Demetris AJ, Burrell BE, Priore A, Bridges ND, Sayre PH
[Reprint] [PubMed]
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Shaked A, DesMarais MR, Kopetskie H, Feng S, Punch J, Levitsky J, Reyes J, Klintmalm G, Demetris AJ, Burrell BE, Priore A, Bridges ND, Sayre PH (2019). Outcomes of immunosuppression minimization and withdrawal early after liver transplantation. Am J Transplant, 19 (5), 1397‐1409.
Cell type–specific immune phenotypes predict loss of insulin secretion in new-onset type 1 diabetes
(2019). JCI Insight, 4 (4), e125556. http://dx.doi.org/10.1172/jci.insight.125556, PMID: 30830868, PMCID: PMC6478408
Dufort MJ, Greenbaum CJ, Speake C, Linsley PS
[Reprint] [PubMed]
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Dufort MJ, Greenbaum CJ, Speake C, Linsley PS (2019). Cell type–specific immune phenotypes predict loss of insulin secretion in new-onset type 1 diabetes. JCI Insight, 4 (4), e125556.
B lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes
(2019). JCI Insight, 4 (4), e126136. http://dx.doi.org/10.1172/jci.insight.126136, PMID: 30830871, PMCID: PMC6478438
Linsley PS, Greenbaum CJ, Speake C, Long SA, Dufort MJ
[Reprint] [PubMed]
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Linsley PS, Greenbaum CJ, Speake C, Long SA, Dufort MJ (2019). B lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes. JCI Insight, 4 (4), e126136.
The MALT1 locus and Peanut Avoidance in the Risk for Peanut Allergy
(2019). J Allergy Clin Immunol, 19, 30279. http://dx.doi.org/10.1016/j.jaci.2019.02.016, PMID: 30825465
Winters A, Bahnson HT, Ruczinski I, Boorgula MP, Malley C, Keramati AR, Chavan S, Larson D, Cerosaletti K, Sayre PH, Plaut M, Du Toit G, Lack G, Barnes KC, Nepom GT, Mathias RA, Immune Tolerance Network LEAP Study Team
[Reprint] [PubMed]
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Winters A, Bahnson HT, Ruczinski I, Boorgula MP, Malley C, Keramati AR, Chavan S, Larson D, Cerosaletti K, Sayre PH, Plaut M, Du Toit G, Lack G, Barnes KC, Nepom GT, Mathias RA, Immune Tolerance Network LEAP Study Team (2019). The MALT1 locus and Peanut Avoidance in the Risk for Peanut Allergy. J Allergy Clin Immunol, 19, 30279.
Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression
(2019). Diabetes, epub ahead of print. http://dx.doi.org/10.2337/db18-1081, PMID: 30894366
Habib T, Long SA, Samuels PL, Brahmandam A, Tatum M, Funk A, Hocking AM, Cerosaletti K, Mason MT, Whalen E, Rawlings DJ, Greenbaum CJ, Buckner JH, the Type 1 Diabetes TrialNet Study Group
[PubMed]
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Habib T, Long SA, Samuels PL, Brahmandam A, Tatum M, Funk A, Hocking AM, Cerosaletti K, Mason MT, Whalen E, Rawlings DJ, Greenbaum CJ, Buckner JH, the Type 1 Diabetes TrialNet Study Group (2019). Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression. Diabetes, epub ahead of print.
Treg gene signatures predict and measure type 1 diabetes trajectory
(2019). JCI Insight, 4 (6), e123879. http://dx.doi.org/10.1172/jci.insight.123879, PMID: 30730852, PMCID: PMC6483004
Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliot T, Dutz JP, Tebbutt SJ, Levings MK
[Reprint] [PubMed]
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Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliot T, Dutz JP, Tebbutt SJ, Levings MK (2019). Treg gene signatures predict and measure type 1 diabetes trajectory. JCI Insight, 4 (6), e123879.
Low-dose Anti-Thymocyte Globulin Preserves C-Peptide and Reduces A1c in New Onset Type 1 Diabetes: Two Year Clinical Trial Data
(2019). Diabetes, db190057. http://dx.doi.org/10.2337/db19-0057, PMID: 30967424
Haller MJ, Long SA, Blanchfield JL, Schatz DA, Skyler JS, Krischer J, Bundy BN, Geyer SM, Warnock MV, Miller J, Atkinson MA, Becker DJ, Baidal DA, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Herold KC, Marks JB, Moran A, Rodriguez H, Russell WE, Wilson DM, Greenbaum CJ, Type 1 Diabetes TrialNet ATG-GCSF Study Group
[Reprint] [PubMed]
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Haller MJ, Long SA, Blanchfield JL, Schatz DA, Skyler JS, Krischer J, Bundy BN, Geyer SM, Warnock MV, Miller J, Atkinson MA, Becker DJ, Baidal DA, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Herold KC, Marks JB, Moran A, Rodriguez H, Russell WE, Wilson DM, Greenbaum CJ, Type 1 Diabetes TrialNet ATG-GCSF Study Group (2019). Low-dose Anti-Thymocyte Globulin Preserves C-Peptide and Reduces A1c in New Onset Type 1 Diabetes: Two Year Clinical Trial Data. Diabetes, db190057.
Self-tolerance curtails the B cell repertoire to microbial epitopes
(2019). JCI Insight, 4 (10). http://dx.doi.org/10.1172/jci.insight.122551, PMID: 31092727
Watanabe A, Su KY, Kuraoka M, Yang G, Reynolds AE, Schmidt AG, Harrison SC, Haynes BF, St Clair EW, Kelsoe G
[Reprint] [PubMed]
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Watanabe A, Su KY, Kuraoka M, Yang G, Reynolds AE, Schmidt AG, Harrison SC, Haynes BF, St Clair EW, Kelsoe G (2019). Self-tolerance curtails the B cell repertoire to microbial epitopes. JCI Insight, 4 (10).
Association of Staphylococcus aureus colonization with food allergy occurs independently of eczema severity
(2019). The Journal of Allergy and Clinical Immunology. http://dx.doi.org/10.1016/j.jaci.2019.04.025
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Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes
(2019). Genes Immun, 20 (4), 293-307. http://dx.doi.org/10.1038/s41435-018-0032-1, PMID: 29925930, PMCID: PMC6477779
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Linsley PS, Greenbaum CJ, Rosasco M, Presnell S, Herold KC, Dufort MJ (2019). Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes. Genes Immun, 20 (4), 293-307.
Disease Activity, ANCA-Type, and Lipid Levels in ANCA-Associated Vasculitis.
(2019). Arthritis Rheumatol, epub ahead of print. http://dx.doi.org/10.1002/art.41006, PMID: 31162829
Wallace ZS, Fu X, Liao K, Kallenberg CGM, Langford CA, Merkel PA, Monach P, Seo P, Specks U, Spiera R, St Clair EW, Zhang Y, Choi H, Stone JH
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Enhancing the Value of Histopathological Assessment of Allograft Biopsy Monitoring
(2019). Transplantation, 103 (7), 1306–1322. http://dx.doi.org/10.1097/TP.0000000000002656, PMID: 30768568
Wood-Trageser MA, Lesniak A, Demetris AJ
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The Association of Pulmonary Haemorrhage, Positive PR3-ANCA and Urinary Red Blood Cell Casts with Venous Thromboembolism in ANCA-Associated Vasculitis
(2019). Arthritis Rheumatol., epub ahead of print. http://dx.doi.org/10.1002/art.41017, PMID: 31216123
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Kronbichler A, Leierer J, Shin JI, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman M, Kallenberg CGM, St Clair EW, Brunetta P, Fervenza FC, Geetha D, Keogh KA, Monach PA, Ytterberg SR, Mayer G, Specks U, Stone JH, RAVE-ITN Research Group (2019). The Association of Pulmonary Haemorrhage, Positive PR3-ANCA and Urinary Red Blood Cell Casts with Venous Thromboembolism in ANCA-Associated Vasculitis. Arthritis Rheumatol., epub ahead of print.
Elicited and pre‐existing anti‐Neu5Gc antibodies differentially affect human endothelial cells transcriptome
(2019). Xenotransplantation, epub ahead of print. http://dx.doi.org/10.1111/xen.12535, PMID: 31293002
Le Berre L, Danger R, Mai HL, Amon R, Leviatan Ben-Ayre S, Bruneau S, Senage T, Perreault H, Teraiya M, Nguyen TVH, Le Tourneau T, Yu H, Chen X, Galli C, Roussel JC, Manez R, Costa C, Brouard S, Galinanes, M, Harris KM, Gitelman S, Cozzi E, Charreau B, Padler-Karavani V, Soulillou JP
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Le Berre L, Danger R, Mai HL, Amon R, Leviatan Ben-Ayre S, Bruneau S, Senage T, Perreault H, Teraiya M, Nguyen TVH, Le Tourneau T, Yu H, Chen X, Galli C, Roussel JC, Manez R, Costa C, Brouard S, Galinanes, M, Harris KM, Gitelman S, Cozzi E, Charreau B, Padler-Karavani V, Soulillou JP (2019). Elicited and pre‐existing anti‐Neu5Gc antibodies differentially affect human endothelial cells transcriptome. Xenotransplantation, epub ahead of print.
The association of serum interleukin-6 levels with clinical outcomes in antineutrophil cytoplasmic antibody-associated vasculitis
(2019). J Autoimmun, epub ahead of print. http://dx.doi.org/10.1016/j.jaut.2019.07.001, PMID: 31320177
Berti A, Warner RL, Johnson KJ, Cornec D, Schroeder DR, Kabat BF, Langford CA, Kallenberg CGM, Seo P, Spiera RF, St Clair EW, Fervenza FC, Stone JH, Monach PA, Specks U, Merkel PA, RAVE-ITN Research Group
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Berti A, Warner RL, Johnson KJ, Cornec D, Schroeder DR, Kabat BF, Langford CA, Kallenberg CGM, Seo P, Spiera RF, St Clair EW, Fervenza FC, Stone JH, Monach PA, Specks U, Merkel PA, RAVE-ITN Research Group (2019). The association of serum interleukin-6 levels with clinical outcomes in antineutrophil cytoplasmic antibody-associated vasculitis. J Autoimmun, epub ahead of print.
Transplantation tolerance in nonhuman primates and humans.
(2019). Bone Marrow Transplant., 54 (Suppl 2), 815-821. http://dx.doi.org/10.1038/s41409-019-0620-3, PMID: 31431694
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Systematic Assessment of Immune Marker Variation in Type 1 Diabetes: A Prospective Longitudinal Study.
(2019). Front Immunol, 10, 2023. http://dx.doi.org/10.3389/fimmu.2019.02023
Speake C, Bahnson HT, Wesley JD, Perdue N, Friedrich D, Pham MN, Lanxon-Cookson E, Kwok WW, Sehested Hanson B, von Herrath M, Greenbaum CJ
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T-cell exhaustion correlates with improved outcomes in kidney transplant recipients
(2019). Kidney Int, 96 (2), 436-449. http://dx.doi.org/10.1016/j.kint.2019.01.040, PMID: 31040060, PMCID: PMC6650324
Fribourg M, Anderson L, Fischman C, Cantarelli C, Perin L, La Manna G, Rahman A, Burrell BE, Heeger PS, Cravedi P
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Fribourg M, Anderson L, Fischman C, Cantarelli C, Perin L, La Manna G, Rahman A, Burrell BE, Heeger PS, Cravedi P (2019). T-cell exhaustion correlates with improved outcomes in kidney transplant recipients. Kidney Int, 96 (2), 436-449.
IgG4 donor-specific HLA antibody profile is associated with subclinical rejection in stable pediatric liver recipients
(2019). Am J Transplant, epub ahead of print. http://dx.doi.org/10.1111/ajt.15621, PMID: 31561279
Jackson AM, Kanaparthi S, Burrell BE, Lucas DP, Vega RM, Demetris AJ, Feng S
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Jackson AM, Kanaparthi S, Burrell BE, Lucas DP, Vega RM, Demetris AJ, Feng S (2019). IgG4 donor-specific HLA antibody profile is associated with subclinical rejection in stable pediatric liver recipients. Am J Transplant, epub ahead of print.
A composite immune signature parallels disease progression across T1D subjects
(2019). JCI Insight, 4 (23), 126917. http://dx.doi.org/10.1172/jci.insight.126917, PMID: 31671072
Speake C, Skinner SO, Berel D, Whalen E, Dufort MJ, Young WC, Odegard JM, Pesenacker AM, Gorus FK, James E, Levings MK, Linsley PS, Akirav EM, Pugliese A, Hessner MJ, Nepom GT, Gottardo R, Long SA
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Speake C, Skinner SO, Berel D, Whalen E, Dufort MJ, Young WC, Odegard JM, Pesenacker AM, Gorus FK, James E, Levings MK, Linsley PS, Akirav EM, Pugliese A, Hessner MJ, Nepom GT, Gottardo R, Long SA (2019). A composite immune signature parallels disease progression across T1D subjects. JCI Insight, 4 (23), 126917.
Alpha‐1 antitrypsin treatment of new‐onset type 1 diabetes: an open‐label, phase I clinical trial (RETAIN) to assess safety and pharmacokinetics
(2018). Pediatr Diabetes., E published ahead of print. http://dx.doi.org/10.1111/pedi.12660, PMID: 29473705
Weir GC, Ehlers MR, Harris KM, Kanaparthi S, Long A, Phippard D, Weiner LJ, Jepson B, McNamara JG, Koulmanda M, Strom TB, ITN RETAIN Study Team
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Weir GC, Ehlers MR, Harris KM, Kanaparthi S, Long A, Phippard D, Weiner LJ, Jepson B, McNamara JG, Koulmanda M, Strom TB, ITN RETAIN Study Team (2018). Alpha‐1 antitrypsin treatment of new‐onset type 1 diabetes: an open‐label, phase I clinical trial (RETAIN) to assess safety and pharmacokinetics. Pediatr Diabetes., E published ahead of print.
Evidence of Chronic Allograft Injury in Liver Biopsies From Long-term Pediatric Recipients of Liver Transplants
(2018). Gastroenterology, E published ahead of print. http://dx.doi.org/10.1053/j.gastro.2018.08.023, PMID: 30144432
Feng S, Bucuvalas JC, Demetris AJ, Burrell BE, Spain KM, Kanaparthi S, Magee JC, Ikle D, Lesniak A, Lozano JJ, Alonso EM, Bray RA, Bridges NE, Doo E, Gebel HM, Gupta NA, Himes RW, Jackson AM, Lobritto SJ, Mazariegos GV, Ng VL, Rand EB, Sherker AH, Sundaram S, Turmelle YP, Sanchez-Fueyo A
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Feng S, Bucuvalas JC, Demetris AJ, Burrell BE, Spain KM, Kanaparthi S, Magee JC, Ikle D, Lesniak A, Lozano JJ, Alonso EM, Bray RA, Bridges NE, Doo E, Gebel HM, Gupta NA, Himes RW, Jackson AM, Lobritto SJ, Mazariegos GV, Ng VL, Rand EB, Sherker AH, Sundaram S, Turmelle YP, Sanchez-Fueyo A (2018). Evidence of Chronic Allograft Injury in Liver Biopsies From Long-term Pediatric Recipients of Liver Transplants. Gastroenterology, E published ahead of print.
Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables
(2018). Diabetologia, Epub ahead of print, 1-8. http://dx.doi.org/10.1007/s00125-018-4722-z, PMID: 30167735
John M. Wentworth, Naiara G. Bediaga, Lynne C. Giles, Mario Ehlers, Stephen E. Gitelman, Susan Geyer, Carmella Evans-Molina, Leonard C. Harrison, the Type 1 Diabetes TrialNet Study Group, the Immune Tolerance Network Study Group
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John M. Wentworth, Naiara G. Bediaga, Lynne C. Giles, Mario Ehlers, Stephen E. Gitelman, Susan Geyer, Carmella Evans-Molina, Leonard C. Harrison, the Type 1 Diabetes TrialNet Study Group, the Immune Tolerance Network Study Group (2018). Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables. Diabetologia, Epub ahead of print, 1-8.
A novel human mast cell activation test for peanut allergy
(2018). J Allergy Clin Immunol, 142 (2), 689-691. http://dx.doi.org/10.1016/j.jaci.2018.03.011, PMID: 29731128, PMCID: PMC6080741
Santos AF, Couto-Francisco N, Becares N, Kwok M, Bahnson HT, Lack G
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Santos AF, Couto-Francisco N, Becares N, Kwok M, Bahnson HT, Lack G (2018). A novel human mast cell activation test for peanut allergy. J Allergy Clin Immunol, 142 (2), 689-691.
Challenges and Opportunities for Biomarkers of Clinical Response to AHSCT in Autoimmunity
(2018). Front Immunol, 9, 100. http://dx.doi.org/10.3389/fimmu.2018.00100, PMID: 29456529, PMCID: PMC5801415
Harris KM, Lu T, Lim N, Turka LA
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Harris KM, Lu T, Lim N, Turka LA (2018). Challenges and Opportunities for Biomarkers of Clinical Response to AHSCT in Autoimmunity. Front Immunol, 9, 100.