Publications

Articles

Perito ER, Martinez M, Turmelle YP, Mason K, Spain KM, Bucuvalas JC, Feng S (2019). Post-transplant biopsy risk for stable long-term pediatric liver transplant recipients:451 percutaneous biopsies from two multi-center immunosuppression withdrawal trials. Am J Transplant. http://dx.doi.org/10.1111/ajt.15255, PMID: 30614623

Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E (2019). Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance. J Immunol, e pub. http://dx.doi.org/10.4049/jimmunol.1801425, PMID: 30683697

Shaked A, DesMarais MR, Kopetskie H, Feng S, Punch J, Levitsky J, Reyes J, Klintmalm G, Demetris AJ, Burrell BE, Priore A, Bridges ND, Sayre PH (2019). Outcomes of immunosuppression minimization and withdrawal early after liver transplantation. Am J Transplant, epub ahead of print. http://dx.doi.org/10.1111/ajt.15205, PMID: 30506630

Dufort MJ, Greenbaum CJ, Speake C, Linsley PS (2019). Cell type–specific immune phenotypes predict loss of insulin secretion in new-onset type 1 diabetes. JCI Insight, 4 (4), e125556. http://dx.doi.org/10.1172/jci.insight.125556, PMID: 30830868, PMCID: PMC6478408

Linsley PS, Greenbaum CJ, Speake C, Long SA, Dufort MJ (2019). B lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes. JCI Insight, 4 (4), e126136. http://dx.doi.org/10.1172/jci.insight.126136, PMID: 30830871, PMCID: PMC6478438

Winters A, Bahnson HT, Ruczinski I, Boorgula MP, Malley C, Keramati AR, Chavan S, Larson D, Cerosaletti K, Sayre PH, Plaut M, Du Toit G, Lack G, Barnes KC, Nepom GT, Mathias RA, Immune Tolerance Network LEAP Study Team (2019). The MALT1 locus and Peanut Avoidance in the Risk for Peanut Allergy. J Allergy Clin Immunol, 19, 30279. http://dx.doi.org/10.1016/j.jaci.2019.02.016, PMID: 30825465

Habib T, Long SA, Samuels PL, Brahmandam A, Tatum M, Funk A, Hocking AM, Cerosaletti K, Mason MT, Whalen E, Rawlings DJ, Greenbaum CJ, Buckner JH, the Type 1 Diabetes TrialNet Study Group (2019). Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression. Diabetes, epub ahead of print. http://dx.doi.org/10.2337/db18-1081, PMID: 30894366

Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliot T, Dutz JP, Tebbutt SJ, Levings MK (2019). Treg gene signatures predict and measure type 1 diabetes trajectory. JCI Insight, 4 (6), e123879. http://dx.doi.org/10.1172/jci.insight.123879, PMID: 30730852, PMCID: PMC6483004

Haller MJ, Long SA, Blanchfield JL, Schatz DA, Skyler JS, Krischer J, Bundy BN, Geyer SM, Warnock MV, Miller J, Atkinson MA, Becker DJ, Baidal DA, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Herold KC, Marks JB, Moran A, Rodriguez H, Russell WE, Wilson DM, Greenbaum CJ, Type 1 Diabetes TrialNet ATG-GCSF Study Group (2019). Low-dose Anti-Thymocyte Globulin Preserves C-Peptide and Reduces A1c in New Onset Type 1 Diabetes: Two Year Clinical Trial Data. Diabetes, db190057. http://dx.doi.org/10.2337/db19-0057, PMID: 30967424

Watanabe A, Su KY, Kuraoka M, Yang G, Reynolds AE, Schmidt AG, Harrison SC, Haynes BF, St Clair EW, Kelsoe G (2019). Self-tolerance curtails the B cell repertoire to microbial epitopes. JCI Insight, 4 (10). http://dx.doi.org/10.1172/jci.insight.122551, PMID: 31092727

Tsilochristou O, Du Toit G, Sayre PH, Roberts G, Lawson K, Sever ML, Bahnson HT, Radulovic S, Basting M, Plaut M, Lack G, Immune Tolerance Network LEAP Study Team (2019). Association of Staphylococcus aureus colonization with food allergy occurs independently of eczema severity. The Journal of Allergy and Clinical Immunology. http://dx.doi.org/10.1016/j.jaci.2019.04.025

Linsley PS, Greenbaum CJ, Rosasco M, Presnell S, Herold KC, Dufort MJ (2019). Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes. Genes Immun, 20 (4), 293-307. http://dx.doi.org/10.1038/s41435-018-0032-1, PMID: 29925930, PMCID: PMC6477779

Wallace ZS, Fu X, Liao K, Kallenberg CGM, Langford CA, Merkel PA, Monach P, Seo P, Specks U, Spiera R, St Clair EW, Zhang Y, Choi H, Stone JH (2019). Disease Activity, ANCA-Type, and Lipid Levels in ANCA-Associated Vasculitis.. Arthritis Rheumatol, epub ahead of print. http://dx.doi.org/10.1002/art.41006, PMID: 31162829

Wood-Trageser MA, Lesniak A, Demetris AJ (2019). Enhancing the Value of Histopathological Assessment of Allograft Biopsy Monitoring. Transplantation, epub ahead of print. http://dx.doi.org/10.1097/TP.0000000000002656, PMID: 30768568

Kronbichler A, Leierer J, Shin JI, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman M, Kallenberg CGM, St Clair EW, Brunetta P, Fervenza FC, Geetha D, Keogh KA, Monach PA, Ytterberg SR, Mayer G, Specks U, Stone JH, RAVE-ITN Research Group (2019). The Association of Pulmonary Haemorrhage, Positive PR3-ANCA and Urinary Red Blood Cell Casts with Venous Thromboembolism in ANCA-Associated Vasculitis. Arthritis Rheumatol., epub ahead of print. http://dx.doi.org/10.1002/art.41017, PMID: 31216123

Le Berre L, Danger R, Mai HL, Amon R, Leviatan Ben-Ayre S, Bruneau S, Senage T, Perreault H, Teraiya M, Nguyen TVH, Le Tourneau T, Yu H, Chen X, Galli C, Roussel JC, Manez R, Costa C, Brouard S, Galinanes, M, Harris KM, Gitelman S, Cozzi E, Charreau B, Padler-Karavani V, Soulillou JP (2019). Elicited and pre‐existing anti‐Neu5Gc antibodies differentially affect human endothelial cells transcriptome. Xenotransplantation, epub ahead of print. http://dx.doi.org/10.1111/xen.12535, PMID: 31293002

Berti A, Warner RL, Johnson KJ, Cornec D, Schroeder DR, Kabat BF, Langford CA, Kallenberg CGM, Seo P, Spiera RF, St Clair EW, Fervenza FC, Stone JH, Monach PA, Specks U, Merkel PA, RAVE-ITN Research Group (2019). The association of serum interleukin-6 levels with clinical outcomes in antineutrophil cytoplasmic antibody-associated vasculitis. J Autoimmun, epub ahead of print. http://dx.doi.org/10.1016/j.jaut.2019.07.001, PMID: 31320177

Sykes M, Griesemer AD (2019). Transplantation tolerance in nonhuman primates and humans.. Bone Marrow Transplant., 54 (Suppl 2), 815-821. http://dx.doi.org/10.1038/s41409-019-0620-3, PMID: 31431694

Savage TM, Shonts BA, Lau S, Obradovic A, Robins H, Shaked A, Shen Y, Sykes M (2019). Deletion of donor-reactive T cell clones following human liver transplantation.. Am J Transplant., epub ahead of print. http://dx.doi.org/10.1111/ajt.15592, PMID: 31509321

Speake C, Bahnson HT, Wesley JD, Perdue N, Friedrich D, Pham MN, Lanxon-Cookson E, Kwok WW, Sehested Hanson B, von Herrath M, Greenbaum CJ (2019). Systematic Assessment of Immune Marker Variation in Type 1 Diabetes: A Prospective Longitudinal Study. . Front Immunol, 10, 2023. http://dx.doi.org/10.3389/fimmu.2019.02023

Bensalem A, Mulleman D, Paintaud G, Azzopardi N, Gouilleux-Gruart V, Cornec D, Specks U, Ternant D (2019). Non-Linear Rituximab Pharmacokinetics and Complex Relationship between Rituximab Concentrations and Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in ANCA-Associated Vasculitis: The RAVE Trial Revisited. Clin Pharmacokinet., epub ahead of print. http://dx.doi.org/10.1007/s40262-019-00826-5, PMID: 31586310

Weir GC, Ehlers MR, Harris KM, Kanaparthi S, Long A, Phippard D, Weiner LJ, Jepson B, McNamara JG, Koulmanda M, Strom TB, ITN RETAIN Study Team (2018). Alpha‐1 antitrypsin treatment of new‐onset type 1 diabetes: an open‐label, phase I clinical trial (RETAIN) to assess safety and pharmacokinetics. Pediatr Diabetes., E published ahead of print. http://dx.doi.org/10.1111/pedi.12660, PMID: 29473705

Feng S, Bucuvalas JC, Demetris AJ, Burrell BE, Spain KM, Kanaparthi S, Magee JC, Ikle D, Lesniak A, Lozano JJ, Alonso EM, Bray RA, Bridges NE, Doo E, Gebel HM, Gupta NA, Himes RW, Jackson AM, Lobritto SJ, Mazariegos GV, Ng VL, Rand EB, Sherker AH, Sundaram S, Turmelle YP, Sanchez-Fueyo A (2018). Evidence of Chronic Allograft Injury in Liver Biopsies From Long-term Pediatric Recipients of Liver Transplants. Gastroenterology, E published ahead of print. http://dx.doi.org/10.1053/j.gastro.2018.08.023, PMID: 30144432

John M. Wentworth, Naiara G. Bediaga, Lynne C. Giles, Mario Ehlers, Stephen E. Gitelman, Susan Geyer, Carmella Evans-Molina, Leonard C. Harrison, the Type 1 Diabetes TrialNet Study Group, the Immune Tolerance Network Study Group (2018). Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables. Diabetologia, Epub ahead of print, 1-8. http://dx.doi.org/10.1007/s00125-018-4722-z, PMID: 30167735

Santos AF, Couto-Francisco N, Becares N, Kwok M, Bahnson HT, Lack G (2018). A novel human mast cell activation test for peanut allergy. J Allergy Clin Immunol, 142 (2), 689-691. http://dx.doi.org/10.1016/j.jaci.2018.03.011, PMID: 29731128, PMCID: PMC6080741

Harris KM, Lu T, Lim N, Turka LA (2018). Challenges and Opportunities for Biomarkers of Clinical Response to AHSCT in Autoimmunity. Front Immunol, 9, 100. http://dx.doi.org/10.3389/fimmu.2018.00100, PMID: 29456529, PMCID: PMC5801415

Savage TM, Shonts BA, Obradovic A, DeWolf S, Lau S, Zuber J, Simpson MT, Berglund E, Fu J, Yang S, Ho S, Tang Q, Turka LA, Shen Y, Sykes M (2018). Early expansion of donor-specific Tregs in tolerant kidney transplant recipients. JCI Insight, 3 (22). http://dx.doi.org/10.1172/jci.insight.124086, PMID: 30429370

Perdigoto AL, Preston-Hurlburt P, Clark P, Long SA, Linsley PS, Harris KM, Gitelman SE, Greenbaum CJ, Gottlieb PA, Hagopian W, Woodwyk A, Dziura J, Herold K (2018). Treatment of type 1 diabetes with teplizumab: clinical and immunological follow-up after 7 years from diagnosis.. Diabetologia, Epub ahead of print, 1-10. http://dx.doi.org/10.1007/s00125-018-4786-9, PMID: 30569273

Hemmings O, Kwok M, McKendry R, Santos AF (2018). Basophil Activation Test: Old and New Applications in Allergy. Current Allergy and Asthma Reports, 18 (12), 77. http://dx.doi.org/10.1007/s11882-018-0831-5, PMID: 30430289, PMCID: PMC6244909

Aranow C, Dall'Era M, Byron M, Ding L, Smilek D, Diamond B, Wofsy D (2018). FRI0305 Phase 2 trial of induction therapy with anti-cd20 (RITUXIMAB) followed by maintenance therapy with anti-baff (BELIMUMAB) in patients with active lupus nephritis. Ann Rheum Dis, 690. http://dx.doi.org/10.1136/annrheumdis-2018-eular.5711

Feng S, Demetris AJ, Kanaparthi S, Ekong UD, Alonso EM, Rosenthal P, Turka LA, Ikle D, Tchao NK, Spain KM, Burrell BE (2017). Five year histological and serological follow-up of operationally tolerant pediatric liver transplant recipients enrolled in WISP-R. Hepatology, 65 (2), 647-60. http://dx.doi.org/10.1002/hep.28681, PMID: 27302659, PMCID: PMC5159322

Khoury SJ, Ding L, Gao W, Arnold DL, Sayre PH, Smilek DE, Rochon J, Byron M, Ryker K, Tosta P, Freedman MS, ACCLAIM Study Group (2017). ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis. Mult Scler. http://dx.doi.org/10.1177/1352458516662727, PMID: 27481207, PMCID: PMC5288398

Wallace ZS, Miloslavsky EM, Cascino M, Unizony SH, Lu N, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera R, St Clair EW, Specks U, Brunetta P, Choi HK, Stone JH (2017). Effect of Disease Activity, Glucocorticoid Exposure, and Rituximab Determine Body Composition Changes during Induction Treatment of ANCA-Associated Vasculitis. Arthritis Care Res (Hoboken)., 69 (7), 1001-10. http://dx.doi.org/10.1002/acr.23099, PMID: 27696762, PMCID: PMC5611860

Shaked A, Sayre P, Li YR, Asare S, DesMarais M, Holmes MV, Guettouche T, Keating BJ, Chang BL, Barnes MR (2017). An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection. Hepatology, 65 (1), 269-80. http://dx.doi.org/10.1002/hep.28786, PMID: 27533743

Cartin-ceba R, Indrakanti D, Specks U, Stone JH, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Spiera RF, Monach PA, Seo P, Tchao NK, Ytterberg SR, St Clair W, Brunetta PG, Song H, Birmingham D, Rovin BH; RAVE-ITN Research Group (2017). The pharmacogenomic association of Fcγ receptors and cytochrome p450 enzymes and response to treatment with rituximab or cyclophosphamide in Anti-Neutrophil Cytoplasmic Antibody-Associated vasculitis. Arthritis Rheumatol, 69 (1), 169-75. http://dx.doi.org/10.1002/art.39822, PMID: 27482943

Pepper RJ, Draibe JB, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Monach PA, Seo P, Spiera R, St Clair EW, Tchao NK, Stone JH, Specks U, Merkel PA, Caplin B, Salama AD; RAVE-ITN Research Group (2017). Association of serum calprotectin (S100A8/S100A9) levels with disease relapses in PR3-ANCA-associated vasculitis. Arthritis Rheumatol, 69 (1), 185-93. http://dx.doi.org/10.1002/art.39814, PMID: 27428710

Unizony S, Miloslavsky EM, Lu N, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, St Clair EW, Ikle D, Tchao NK, Ding L, Brunetta P, Monach PA, Fervenza F, Stone JH, Specks U; RAVE-ITN Research Group, Villarreal M, Kallenberg CM, Choi HK1 (2017). Clinical outcomes of treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis based on ANCA type. Ann Rheum Dis, 75 (6), 1166-9. http://dx.doi.org/10.1136/annrheumdis-2015-208073, PMID: 26621483, PMCID: PMC4908815

Scadding GW, Calderon MA, Shamji MH, Eifan AO, Penagos M, Sever ML, Bahnson HT, Lawson K, Harris KM, Lim N, Tchao NK, Togias A, Dumitru F, Plough AG, Panza JL, Qin T, Durham SR; Immune Tolerance Network GRASS Study Team (2017). Effect of 2 Years of Treatment With Sublingual Grass Pollen Immunotherapy on Nasal Response to Allergen Challenge at 3 Years Among Patients With Moderate to Severe Seasonal Allergic Rhinitis: The GRASS Randomized Clinical Trial. JAMA, 317 (6), 615-625. http://dx.doi.org/10.1001/jama.2016.21040, PMID: 28196255

Lim N, Brouard S, Harris KM, Ehlers MR, Gitelman SE, Soulillou JP, Salama A1, Evanno G, Rousse J, Le Berre L, Nicot A (2017). Anti-Gal and anti-Neu5Gc responses in nonimmunosuppressed patients following treatment with rabbit anti-thymocyte polyclonal IgGs. Transplantation, 101 (10), 2501-07. http://dx.doi.org/10.1097/TP.0000000000001686, PMID: 28198767

Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stüve O, Arnold DL, Georges GE, Wundes A, Kraft GH, Bowen JD, Steinmiller KC, Wener MH (2017). High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS. Neurology, Feb 1 2017. http://dx.doi.org/10.1212/WNL.0000000000003660, PMID: 28148635, PMCID: PMC5331868

Clain JM, Hummel AM, Stone JH, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, McCune WJ, Specks U; WGET and RAVE-ITN Research Groups (2017). Immunoglobulin (Ig)M antibodies to proteinase 3 in granulomatosis with polyangiitis and microscopic polyangiitis. Clin Exp Immunol, 188 (1), 174-81. http://dx.doi.org/0.1111/cei.12925, PMID: 28076879, PMCID: PMC5343341

Asare A, Kanaparthi S, Lim N, Phippard D, Burrell BE, Bridges N, Sanz I, Newell KA, Turka LA, Vincenti F, Friedewald J, Pavlakis M, Poggio E, Heeger P, Mannon R, Morrison Y, Chandraker A (2017). B Cell Receptor Genes Associated with Tolerance Identify a Cohort of Immunosuppressed Patients with Improved Renal Allograft Graft Function. Am J Transplant. http://dx.doi.org/10.1111/ajt.14283, PMID: 28371372, PMCID: PMC5620117

Sprangers B, DeWolf S, Morokata T, LoCascio SA, Shonts B, Zuber J, Morris H, Zorn E, Preffer FI, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M, Savage TM, Obradovic A, Lau SP, Shah R, Steshenko V, Olek S (2017). Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance. Am J Transplant. http://dx.doi.org/10.1111/ajt.14251, PMID: 28251801, PMCID: PMC5519438

Calatroni A, Liu AH, Gergen PJ, Gruchalla RS, Khurana Hershey GK, Kercsmar CM, Teach SJ, Wildfire JJ, Busse WW, Szefler SJ, Hoch HE, West JB, Kim H, Lamm C, Makhija MM, Mitchell HE (2017). Can we predict fall asthma exacerbations? Validation of the seasonal asthma exacerbation index. J Allergy Clin Immunol. http://dx.doi.org/10.1016/j.jaci.2017.01.026, PMID: 28238748, PMCID: PMC5568982

Danger R, Chesneau M, Paul C, Guérif P, Durand M, Newell KA, Kanaparthi S, Turka LA, Soulillou JP, Houlgatte R, Giral M, Ramstein G, Brouard S (2017). A composite score associated with spontaneous operational tolerance in kidney transplant recipients. Kidney Int, 91 (1), 1473-81. http://dx.doi.org/10.1016/j.kint.2016.12.020, PMID: 28242033, PMCID: PMC5432017

Esquivel A, Busse WW, Calatroni A, Togias AG, Grindle KG, Bochkov YA, Gruchalla RS, Kattan M, Kercsmar CM, Khurana Hershey G, Kim H, Lebeau P, Liu AH, Szefler SJ, Teach SJ, West JB, Wildfire J, Pongracic JA, Gern JE (2017). Effects of Omalizumab on Rhinovirus Infections, Illnesses and Exacerbations of Asthma. Am J Respir Crit Care Med, 196 (8), 985-92. http://dx.doi.org/10.1164/rccm.201701-0120OC, PMID: 28608756, PMCID: PMC5649984

Yang J, DeBerg HA, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Gottardo R, Nepom GT, Linsley PS, Cerosaletti K, Barahmand-Pour-Whitman F, Dufort MJ, Murray SA, Israelsson E, Wambre E, Prlic M (2017). Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes. J Immunol, 199 (1), 323-35. http://dx.doi.org/10.4049/jimmunol.1700172, PMID: 28566371, PMCID: PMC5499675

A Long, J Thorpe, KC Herold, M Ehlers, S Sanda, N Lim, PS Linsley, GT Nepom, KM Harris (2017). Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 Diabetes. Cell Immunol. http://dx.doi.org/10.1016/j.cellimm.2017.07.007, PMID: 28844471, PMCID: PMC5614459

N Lim, DE Smilek, L Ding, SG Murray, B Diamond, D Wofsy (2017). Correlation of hypogammaglobulinaemia with proteinuria, and the relationship between hypogammaglobulinaemia and infection in active lupus nephritis. Lupus Sci Med, 4 (1). http://dx.doi.org/10.1136/lupus-2017-000229, PMID: 29214037, PMCID: PMC5704742

Gill MA, Liu AH, Calatroni A, Gern JE, Togias A, Busse WW, Krouse RZ, Shao B, Schiltz A (2017). Enhanced plasmacytoid dendritic cell antiviral responses after omalizumab. J Allergy Clin Immunol. http://dx.doi.org/10.1016/j.jaci.2017.07.035, PMID: 28870461

Geetha D, Specks U, Kallenberg CGM, Lim N, Spiera R, St Clair EW, Merkel PA, Seo P, Monach PA, Fessler BJ, Langford CA, Hoffman GS, Stone JH, Sethi S, De Vriese AS, Lepori N, Sharma R, Fervenza FC; RAVE-ITN Research Group (2017). Interstitial Immunostaining and Renal Outcomes in Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis. Am J Nephrol. http://dx.doi.org/10.1159/000480443, PMID: 28881339

Keever-Taylor CA, Heimfeld S, Steinmiller KC, Nash RA, Sullivan KM, Czarniecki CW, Granderson TC, Goldstein JS, Griffith LM (2017). Manufacture of Autologous CD34+ Selected Grafts in the NIAID-Sponsored HALT-MS and SCOT Multicenter Clinical Trials for Autoimmune Diseases. Biol Blood Marrow Transplant, 23 (9), 1463-1472. http://dx.doi.org/10.1016/j.bbmt.2017.05.018, PMID: 28602891, PMCID: PMC5761325

Merkel PA, Monach PA, Carette S, Cuthbertson D, Hoffman GS, Langford CA, Specks U, Spiera RF, St Clair EW, Stone JH, Ytterberg SR, Xie G, Ji X, Ciavatta DJ, Byun J, Pinder BD, Zhao A, Zhang J, Tadesse Y, Qian D, Weirauch M, Nair R, Tsoi A, Pagnoux C, Chung S, Davis JC Jr, Dellaripa PF, Forbess L, Gewurz-Singer O, Khalidi N, Koening C, Mahr AD, McAlear C, Moreland L, Seo EP, Sreih A, Elder JT, Qu J, Ochi T, Hirano N, Edberg JC, Falk RJ, Amos CI, Siminovitch KA; Vasculitis Clinical Research Consortium (2017). Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis. Arthritis Rheumatol, 69 (5), 1054-66. http://dx.doi.org/10.1002/art.40034, PMID: 28029757, PMCID: PMC5434905

Du Toit G, Sayre PH, Roberts G, Lawson K, Sever ML, Bahnson HT, Fisher HR, Feeney M, Radulovic S, Basting M, Plaut M, Lack G; Immune Tolerance Network LEAP Study Team (2017). The allergen-specificity of early peanut consumption and the impact on the development of allergic disease in the LEAP Study Cohort. J Allergy Clin Immunol, 141 (4), 1343-1353. http://dx.doi.org/10.1016/j.jaci.2017.09.034, PMID: 29097103, PMCID: PMC5889963

Greenhawt M, Fleischer DM, Chan ES, Venter C, Stukus D, Gupta R, Spergel JM (2017). LEAPing through the looking glass: secondary analysis of the effect of skin test size and age of introduction on peanut tolerance after early peanut introduction. Allergy, 72 (8), 1254-60. http://dx.doi.org/10.1111/all.13100, PMID: 27896827, PMCID: PMC5447487

Karnell FG, Lin D, Motley S, Duhen T, Lim N, Campbell DJ, Turka LA, Maecker HT, Harris KM (2017). Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation. Clin Exp Immunol, 189 (3), 268-78. http://dx.doi.org/10.1111/cei.12985, PMID: 28498568, PMCID: PMC5543487

Shamji MH, Harris KM, Qin T, Wambre E, Scadding GW, Wurtzen PA, Till SJ, Togias A, Nepom GT, Kwok WW, Durham SR, Renand A (2017). Synchronous Immune Alterations Mirror Clinical Response During Allergen Immunotherapy. J Allergy Clin Immunol. , PMID: 29128670, PMCID: PMC5938141

Du Toit G, Plaut M, Lack G, Sampson H, Burks W, Akdis C (2017). Food Allergy: Update on Prevention and Tolerance. J Allergy Clin Immunol. http://dx.doi.org/10.1016/j.jaci.2017.11.010, PMID: 29191680

Sicherer SH, Sampson HA (2017). Food Allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention and management. J Allergy Clin Immunol. http://dx.doi.org/10.1016/j.jaci.2017.11.003, PMID: 29157945

Gao B1, Gu Y, Rong C, Moore C, Porcheray F, Wong W, Preffer F, Saidman Sl, Fu Y, Cosimi B, Sachs DH, Kawai T, Sykes M, Zorn E (2017). Dynamics of B Cell Recovery In Kidney/Bone Marrow Transplant Recipients. Transplantation, 101 (11), 2722-2730. http://dx.doi.org/10.1097/TP.0000000000001789, PMID: 28422925, PMCID: PMC5648631

Amon R, Ben-Arye SL, Engler L, Yu H, Lim N, Berre LL, Harris KM, Ehlers MR, Gitelman SE, Chen X, Soulillou JP, Padler-Karavani V (2017). Glycan microarray reveal induced IgGs repertoire shift against a dietary carbohydrate in response to rabbit anti-human thymocyte therapy. Oncotarget, 8 (68), 112236-112244. http://dx.doi.org/10.18632/oncotarget.23096, PMID: 29348821, PMCID: PMC5762506

Brennan DC, Kopetskie HA, Sayre PH, Alejandro R, Cagliero E, Shapiro AM, Goldstein JS, DesMarais MR, Booher S, Bianchine PJ (2016). Long-Term Follow-Up of the Edmonton Protocol of Islet Transplantation in the United States. Am J Transplant, 16 (2), 509-17. http://dx.doi.org/10.1111/ajt.13458, PMID: 26433206

Tooley JE, Vudattu N, Choi J, Cotsapas C, Devine L, Raddassi K, Ehlers MR, Harris KM, Kanaparthi S, Phippard D, Herold KC, McNamara JG (2016). Changes in T-cell subsets identify responders to FcR non-binding anti-CD3 mAb (teplizumab) in patients with Type 1 diabetes. Eur J Immunol, 46 (1), 230-41. http://dx.doi.org/10.1002/eji.201545708, PMID: 26518356, PMCID: PMC4882099

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Mathew JM, Levitsky J, Miller J, Leventhal JR, Salomon DR, Kurian SM, Friedewald JJ, Gallon L, Konieczna I, Tambur AR, Charette J, Jie C, Kanwar YS, Abecassis MM (2016). Nonchimeric HLA-Identical Renal Transplant Tolerance: Regulatory Immunophenotypic/Genomic Biomarkers. Am J Transplant, 16 (1), 221-34. http://dx.doi.org/10.1111/ajt.13416, PMID: 26227106, PMCID: PMC4718825

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Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stüve O, Arnold DL, Spychala ME, McConville KC, Harris KM, Phippard D, Georges GE, Wundes A, Kraft GH, Bowen JD (2015). High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for relapsing-remitting multiple sclerosis (HALT-MS): A 3-year interim report. JAMA Neurology, 72 (2), 159-69. http://dx.doi.org/10.1001/jamaneurol.2014.3780, PMID: 25546364, PMCID: PMC5261862

Morris H, DeWolf S, Robins H, Sprangers B, LoCascio SA, Shonts BA, Kawai T, Wong W, Yang S, Zuber J, Shen Y, Sykes M (2015). Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients. Sci Transl Med, 7 (272), 272ra10. http://dx.doi.org/10.1126/scitranslmed.3010760, PMID: 25632034, PMCID: PMC4360892

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Unizony S, Lim N, Phippard DJ, Carey VJ, Miloslavsky EM, Tchao NK, Ikle D, Asare AL, Merkel PA, Monach PA, Seo P, St Clair EW, Langford CA, Spiera R, Hoffman GS, Kallenberg CG, Specks U, Stone JH. (2015). Peripheral CD5+ B-cells in antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheumatol, 67 (2), 535-44. http://dx.doi.org/10.1002/art.38916, PMID: 25332071, PMCID: PMC4497572

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Mark R. Rigby, Kristina M. Harris, Ashley Pinckney, Linda A. DiMeglio, Marc S. Rendell, Eric I. Felner, Jean M. Dostou, Stephen E. Gitelman, Kurt J. Griffin, Eva Tsalikian, Peter A. Gottlieb, Carla J. Greenbaum, Nicole A. Sherry, Wayne V. Moore, Roshanak Monzavi, Steven M. Willi, Philip Raskin, Lynette Keyes-Elstein, S. Alice Long, Sai Kanaparthi, Noha Lim, Deborah Phippard, Carol L. Soppe, Margret L. Fitzgibbon, James McNamara, Gerald T. Nepom, Mario R. Ehlers, Immune Tolerance Network T1DAL Study Group (2015). Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients. J Clin Invest, 125 (8), 3285-96. http://dx.doi.org/10.1172/JCI81722, PMID: 26193635, PMCID: PMC4623571

Grayson PC, Carmona-Rivera C, Xu L, Lim N, Gao Z, Asare AL, Specks U, Stone JH, Seo P, Spiera RF, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Ytterberg SR, Phippard DJ, Merkel PA, Kaplan MJ, Monach PA; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group (2015). Neutrophil-Related Gene Expression and Low-Density Granulocytes Associated With Disease Activity and Response to Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 67 (7), 1922-32. http://dx.doi.org/10.1002/art.39153, PMID: 25891759, PMCID: PMC4485551

Newell KA, Asare A, Sanz I, Wei C, Rosenberg A, Gao Z, Kanaparthi S, Asare S, Lim N, Stahly M, Howell M, Knechtle S, Kirk A, Marks WH, Kawai T, Spitzer T, Tolkoff-Rubin N, Sykes M, Sachs DH, Cosimi AB, Burlingham WJ, Phippard D, Turka LA (2015). Longitudinal Studies of a B Cell-Derived Signature of Tolerance in Renal Transplant Recipients. Am J Transplant, 15 (11), 2908-20. http://dx.doi.org/10.1111/ajt.13480, PMID: 26461968, PMCID: PMC4725587

Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Ding L, Ikle D, Villareal M, Lim N, Brunetta P, Fervenza FC, Monach PA, Stone JH; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group. (2015). Outcomes of nonsevere relapses in antineutrophil cytoplasmic antibody-associated vasculitis treated with glucocorticoids. Arthritis Rheumatol, 67 (6), 1629-36. http://dx.doi.org/10.1002/art.39104, PMID: 25776953

Geetha D, Specks U, Stone JH, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Fessler BJ, Ding L, Tchao NK, Ikle D, Jepson B, Brunetta P, Fervenza FC; Rituximab for ANCA-Associated Vasculitis Immune Tolerance Network Research Group. (2015). Rituximab versus cyclophosphamide for ANCA-associated vasculitis with renal involvement. J Am Soc Nephrol, 26 (4), 796-85. http://dx.doi.org/10.1681/ASN.2014010046, PMID: 25381429, PMCID: PMC4378104

Burks AW, Wood RA, Jones SM, Scurlock AM, Vickery BP, Liu AH, Lindblad R, Plaut M, Sicherer SH, Fleischer DM, Henning AK, Dawson P, Sampson HA; Consortium of Food Allergy Research. (2015). Sublingual immunotherapy for peanut allergy: Long-term follow-up of a randomized multicenter trial. J Allergy Clin Immunol, 135 (5), 1240-8. http://dx.doi.org/10.1016/j.jaci.2014.12.1917, PMID: 25656999, PMCID: PMC4527157

Scadding GW, Penagos M, Switzer A, Phippard D, Togias A, Shamji MH, Durham SR, Eifan AO, Lao-Araya M, Poon SY, Steveling E, Yan R (2015). Effect of grass pollen immunotherapy on clinical and local immune response to nasal allergen challenge. Allergy, 70 (6), 689-96. http://dx.doi.org/10.1111/all.12608, PMID: 25773990, PMCID: PMC4826905

Speake C, Odegard JM (2015). Evaluation of Candidate Biomarkers of Type 1 Diabetes via the Core for Assay Validation. Biomark Insights, 10 (Suppl 4), 19-24. http://dx.doi.org/10.4137/BMI.S29697, PMID: 26462120, PMCID: PMC4589091

Fuchs EJ (2015). HLA-haploidentical blood or marrow transplantation with high-dose, post-transplantation cyclophosphamide. Bone Marrow Transplant, 50 (Suppl 2), S31-6. http://dx.doi.org/10.1038/bmt.2015.92, PMID: 26039204, PMCID: PMC4634886

Rosenthal P, Alonso EM, Ekong UD, Lobritto SJ, Feng S, Perito ER, Mohammad S (2015). Posttransplant Metabolic Syndrome in the Withdrawal of Immunosuppression in Pediatric Liver Transplant Recipients (WISP-R) Pilot Trial. Am J Transplant, 15 (3), 779-85. http://dx.doi.org/10.1111/ajt.13024, PMID: 25648649, PMCID: PMC4426259

Li YR, van Setten J, Verma SS, Lu Y, Holmes MV, Gao H, Lek M, Nair N, Chandrupatla H, Chang B, Karczewski KJ, Wong C, Mohebnasab M, Mukhtar E, Phillips R, Tragante V, Hou C, Steel L, Lee T, Garifallou J, Guettouche T, Cao H, Guan W, Himes A, van Houten J, Pasquier A, Yu R, Carrigan E, Miller MB, Schladt D, Akdere A, Gonzalez A, Llyod KM, McGinn D, Michaud Z, Colasacco A, Snyder J, Thomas K, Wang T, Wu B, Alzahrani AJ, Al-Ali AK, Al-Muhanna FA, Al-Rubaish AM, Al-Mueilo S, Monos DS, Murphy B, Olthoff KM, Wijmenga C, Webster T, Kamoun M, Balasubramanian S, Lanktree MB, Oetting WS, Garcia-Pavia P, MacArthur DG, Hakonarson H, Birdwell KA, Jacobson PA, Ritchie MD, Asselbergs FW, Israni AK, Shaked A, Keating BJ, Gangasan Ai, de Bakker PIW (2015). Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies. Genome Med, 7 (1), 90. http://dx.doi.org/10.1186/s13073-015-0211-x., PMID: 26423053, PMCID: PMC4589899

Holland CJ, Dolton G, Scurr M, Ladell K, Schauenburg AJ, Miners K, Madura F, Sewell AK, Price DA, Cole DK, Godkin AJ (2015). Enhanced Detection of Antigen-Specific CD4+ T Cells Using Altered Peptide Flanking Residue Peptide-MHC Class II Multimers. J Immunol, 195 (12), 5827-36. http://dx.doi.org/10.4049/jimmunol.1402787, PMID: 26553072, PMCID: PMC4671089

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International Genetics & Translational Research in Transplantation Network (iGeneTRAiN) (2015). Design and Implementation of the International Genetics and Translational Research in Transplantation Network. Transplantation, 99 (11), 2401-12. http://dx.doi.org/10.1097/TP.0000000000000913, PMID: 26479416, PMCID: PMC4623847

Teach SJ, Gill MA, Togias A, Sorkness CA, Arbes SJ Jr, Calatroni A, Wildfire JJ, Gergen PJ, Cohen RT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Gruchalla RS, Liu AH, Zoratti EM, Kattan M, Grindle KA, Gern JE, Busse WW, Szefler SJ1 (2015). Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations. J Allergy Clin Immunol, 136 (6), 1476-85. http://dx.doi.org/10.1016/j.jaci.2015.09.008, PMID: 26518090, PMCID: PMC4679705

Bluestone JA, Buckner JH, Gitelman SE, Herold KC, Long SA, Rieck M, Sayre PH, Tang Q, Fitch M, Gupta S, Hellerstein MK, Lares A, Lee MR, Li K, Liu W, Masiello LM, Nguyen V, Putnam AL (2015). Type 1 diabetes immunotherapy using polyclonal regulatory T cells. Sci Transl Med, 7 (315), 315ra189. http://dx.doi.org/10.1126/scitranslmed.aad4134, PMID: 26606968, PMCID: PMC4729454

Muraro PA, Robins H, Malhotra S, Howell M, Phippard D, Desmarais C, de Paula Alves Sousa A, Griffith LM, Lim N, Nash RA, Turka LA (2014). T cell repertoire following autologous stem cell transplantation for multiple sclerosis . J Clin Invest, 124 (3), 1168-72. http://dx.doi.org/10.1172/JCI71691, PMID: 24531550, PMCID: PMC3934160

Finak G, Jiang W, Krouse K, Wei C, Sanz I, Phippard D, Asare D, De Rosa SC, Self S, Gottardo R (2014). High-throughput flow cytometry data normalization for clinical trials. Cytometry A, 85 (3), 277-86. http://dx.doi.org/10.1002/cyto.a.22433, PMID: 24382714, PMCID: PMC3992339

Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St. Clair EW, Tchao NK, Viviano L, Ding L, Ikle D, Villareal M, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group (2014). Rituximab for the Treatment of Relapses in antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheumatol, 66 (11), 3151-59. http://dx.doi.org/10.1002/art.38788, PMID: 25047592, PMCID: PMC4229846

Vickery BP, Scurlock AM, Kulis M, Steele PH, Kamilaris J, Berglund JP, Burk C, Hiegel A, Carlisle S, Christie L, Perry TT, Pesek RD, Sheikh S, Virkud Y, Smith PB, Shamji MH, Durham SR, Jones SM, Burks AW (2014). Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy. J Allergy Clin Immunol, 133 (2), 468-75. http://dx.doi.org/10.1016/j.jaci.2013.11.007, PMID: 24361082, PMCID: PMC3960331

Wood RA, Togias A, Wildfire J, Visness CM, Matsui EC, Gruchalla R, Hershey G, Liu AH, O’Connor GT, Pongracic JA, Zoratti E, Little F, Granada M, Kennedy S, Durham SR, Shamji MH, Busse WW. (2014). Development of cockroach immunotherapy by the Inner-City Asthma Consortium. J Allergy Clin Immunol, 133 (3), 846-52. http://dx.doi.org/10.1016/j.jaci.2013.08.047, PMID: 24184147, PMCID: PMC3943647

Ang M, Meyer C, Brendel MD, Bretzel RG, Linn T (2014). Magnitude and mechanisms of glucose counterregulation following islet transplantation in patients with type 1 diabetes suffering from severe hypoglycaemic episodes. Diabetologia, 57 (3), 623-32. http://dx.doi.org/10.1007/s00125-013-3120-9, PMID: 24305963

The ACCESS Trial Group (2014). Treatment of lupus nephritis with abatacept: The Abatacept and Cyclophosphamide Combination Efficacy and Safety Study. Arthritis & Rheumatology, 66 (11), 3096-104. http://dx.doi.org/10.1002/art.38790, PMID: 25403681, PMCID: PMC4528976

Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman Sl, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Gao B, Wong W, Morris H, LoCascio SA, Sayre P, Shonts B, Williams WW, Colvin RB, Smith R-N, Sykes M, Cosimi AB. (2014). Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression. Am J Transplant, 14 (7), 1599-1611. http://dx.doi.org/10.1111/ajt.12731, PMID: 24903438, PMCID: PMC4228952

Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, Nepom G, Ehlers M, Staeva T, Garren H, Steinman L, Chan AC, von Herrath M (2013). Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: Immunologic effects and efficacy in NOD mice. PLoS One, 8 (2), e54712. http://dx.doi.org/10.1371/journal.pone.0054712, PMID: 23405091, PMCID: PMC3566105

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Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA, the AbATE Study Team (2013). Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: Metabolic and immunologic features at baseline identify a subgroup of responders. Diabetes, 62 (11), 3766-74. http://dx.doi.org/10.2337/db13-0345, PMID: 23835333, PMCID: PMC3806618

Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Fessler BJ, Ding L, Viviano L, Tchao NK, Phippard DJ, Asare AL, Lim N, Ikle D, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Mueller M, Sejismundo LP, Mieras K, Stone JH for the RAVE-ITN Research Group (2013). Efficacy of Remission-Induction Regimens for ANCA-Associated Vasculitis. N Engl J Med, 369 (5), 417-27. http://dx.doi.org/10.1056/NEJMoa1213277, PMID: 23902481

Gitelman SE, Gottlieb PA, Rigby MR, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, Ding L, Bluestone JA, Ehlers MR, the START Study Team (2013). Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial. Lancet Diabetes Endocrinol, 1 (4), 306-16. http://dx.doi.org/10.1016/S2213-8587(13)70065-2, PMID: 24622416

Rigby MR, DiMeglio LA, Rendell MS, Felner E, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, Immune Tolerance Network T1DAL Study Team (2013). Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Diabetes Endocrinol, 1 (4), 284-94. http://dx.doi.org/10.1016/S2213-8587(13)70111-6, PMID: 24622414, PMCID: PMC3957186

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Viglietta V, Bourcier K, Buckle GJ, Healy B, Weiner HL, Hafler DA, Egorova S, Guttmann CRG, Rusche JR, Khoury SJ (2008). CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial. Neurology, 71 (12), 917-24. http://dx.doi.org/10.1212/01.wnl.0000325915.00112.61, PMID: 18794494

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Lee JA, Spidlen J, Boyce K, Cai J, Crosbie N, Dalphin M, Furlong J, Gasparetto M, Goldberg M, Goralczyk EM, Hyun B, Jansen K, Kollmann T, Kong M, Leif R, McWeeney S, Moloshok TD, Moore W, Nolan G, Nolan J, Nikolich-Zugich J, Parrish D, Purcell B, Qian Y, Selvaraj B, Smith C, Tchuvatkina O, Wertheimer A, Wilkinson P, Wilson C, Wood J, Zigon R; International Society for Advancement of Cytometry Data Standards Task Force, Scheuermann RH, Brinkman RR (2008). MIFlowCyt: the minimum information about a Flow Cytometry Experiment. Cytometry, 73 (10), 926-30. http://dx.doi.org/10.1002/cyto.a.20623, PMID: 18752282, PMCID: PMC2773297

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Feng S (2008). Long-term management of immunosuppression after pediatric liver transplantation: is minimization or withdrawal desirable or possible or both?. Curr Opin Organ Transplant, 13 (5), 506-12. http://dx.doi.org/10.1097/MOT.0b013e328310b0f7, PMID: 19060534, PMCID: PMC2727645

Levesque MC, St Clair EW. (2008). B cell-directed therapies for autoimmune disease and correlates of disease response and relapse. J Allergy Clin Immunol, 121 (1), 13-21. http://dx.doi.org/10.1016/j.jaci.2007.11.030, PMID: 18206502

Xu Q, Lee J, Jankowska-Gan E, Schultz J, Roennburg DA, Haynes LD, Kusaka S, Sollinger HW, Knechtle SJ, Vanbuskirk AM, Torrealba JR, Burlingham WJ (2007). Human CD4+CD25low Adaptive T Regulatory Cells Suppress Delayed-Type Hypersensitivity during Transplant Tolerance. J Immunol, 178 (6), 3983-95. , PMID: 17339499

Derks RA, Jankowska-Gan E, Xu Q, Burlingham WJ (2007). Dendritic cell type determines the mechanism of bystander suppression by adaptive T regulatory cells specific for the minor antigen HA-1. J Immunol, 179 (6), 3443-51. , PMID: 17785778

Klunker S, Saggar LR, Seyfert-Margolis V, Asare AL, Casale TB, Durham SR, Francis JN, Immune Tolerance Network Group (2007). Combination treatment with omalizumab and rush immunotherapy for ragweed-induced allergic rhinitis: Inhibition of IgE-facilitated allergen binding. J Allergy Clin Immunol, 120 (3), 688-95. , PMID: 17631952

Baschal EE, Aly TA, Babu SR, Fernando MS, Yu L, Miao D, Barriga KJ, Norris JM, Noble JA, Erlich HA, Rewers MJ, Eisenbarth GS (2007). HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4DQB1*0302 DAISY population. Diabetes, 56 (9), 2405-2409. , PMID: 17513705

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Wang J, Miao D, Babu S, Yu J, Barker J, Klingensmith G, Rewers M, Eisenbarth GS, Yu L (2007). Prevelence of autoantibody-negative diabetes is not rare at all ages and increases with older age and obesity. J Clin Endocrinol, 92 (1), 88-92. , PMID: 17062766

Yu L, Wang J, O'Dell JR, Oates J, Arend WP, Eisenbarth GS (2007). Anti-dsDNA antibody assay: high specificity and sensitivity with a filtration radioassay in comparison to low specificity with standard ELISA. J Rheumatol, 34 (4), 734-739. , PMID: 17407230

Zhang L, Barker JM, Babu S, Su M, Stenerson M, Cheng M, Shum A, Zamir E, Badolato R, Law A, Eisenbarth GS, Anderson MS (2007). A robust immunoassay for anti-interferon autoantibodies that is highly specific for patients with autoimmune polyglandular syndrome type 1. Clin Immunol, 125 (2), 131-137. , PMID: 17825626, PMCID: PMC2080870

Kis J, Engelmann P, Farkas K, Richman G, Eck S, Lolley J, Jalahej H, Borowiec M, Kent SC, Treszl A, Orban T. (2007). Reduced CD4+ subset and Th1 bias of the human iNKT cells in Type 1 diabetes mellitus. J Leukoc Biol, 81 (3), 654-662. , PMID: 17151140

Aly TA, Eller E, Ide A, Gowan K, Babu SR, Erlich HA, Rewers MJ, Eisenbarth GS, Fain PR (2006). Multi-SNP analysis of MHC region: Remarkable conservation of HLA-A1-B8-DR3 haplotype. Diabetes, 55 (5), 1265-1269. , PMID: 16644681

Aly TA, Ide A, Jahromi MM, Barker JM, Fernando MS, Babu SR, Yu L, Miao D, Erlich HA, Fain PR, Barriga KJ, Norris JM, Rewers MJ, Eisenbarth GS (2006). Extreme genetic risk for type 1A diabetes. Proc Natl Acad Sci, 103 (38), 14074-14079. , PMID: 16966600, PMCID: PMC1563993

Casale TB, Busse WW, Kline JN, Ballas ZK, Moss MH, Townley RG, Mokhtarani M, Seyfert-Margolis V, Asare A, Bateman K, Deniz Y, Immune Tolerance Network (2006). Omalizumab pretreatment decreases acute reactions following rush immunotherapy for ragweed-induced seasonal allergic rhinitis. J Allergy Clin Immunol, 117 (1), 134-140. , PMID: 16387596

Creticos PS, Schroeder JT, Hamilton RG, Balcer-Whaley SL, Khattignavong AP, Lindblad R, Li H, Coffman R, Seyfert V, Eiden JJ, Broide D, Immune Tolerance Network Group (2006). Immunotherapy with a ragweed–toll-like receptor 9 agonist vaccine for allergic rhinitis. New Engl J Med, 355 (14), 1445-1455. , PMID: 17021320

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Seyfert-Margolis V, Gisler TD, Asare AL, Wang RS, Dosch HM, Brooks-Worrell B, Eisenbarth GS, Palmer JP, Greenbaum CJ, Gitelman SE, Nepom GT, Bluestone JA, Herold KC (2006). Analysis of T cell assays to measure autoimmune responses in subjects with type 1 diabetes: results of a blinded controlled study. Diabetes, 55 (9), 2588-2594. , PMID: 16936208

Shamji MH, Wilcock LK, Wachholz PA, Dearman RJ, Kimber I, Wurtzen PA, Larché M, Durham SR, Francis JN (2006). The IgE-facilitated allergen binding (FAB) assay: validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses. J Immunol Meth, 317 (1-2), 71-79. , PMID: 17070537, PMCID: PMC1934503

Shapiro AM, Ricordi C, Hering BJ, Auchincloss H, Lindblad R, Robertson RP, Secchi A, Brendel MD, Berney T, Brennan DC, Cagliero E, Alejandro R, Ryan EA, DiMercurio B, Morel P, Polonsky KS, Reems JA, Bretzel RG, Bertuzzi F, Froud T, Kandaswamy R, Sutherland DE, Eisenbarth G, Segal M, Preiksaitis J, Korbutt GS, Barton FB, Viviano L, Seyfert-Margolis V, Bluestone J, Lakey JR (2006). International trial of the Edmonton protocol for islet transplantation. New Engl J Med, 355 (13), 1318-1330. , PMID: 17005949

Bourdette DN, Edmonds E, Smith C, Bowen JD, Guttmann CR, Nagy ZP, Simon J, Whitham R, Lovera J, Yadav V, Mass M, Spencer L, Culbertson N, Bartholomew RM, Theofan G, Milano J, Offner H, Vandenbark AA (2005). A highly immunogenic trivalent T cell receptor peptide vaccine. Multiple Sclerosis, 11 (5), 552-561. , PMID: 16193893

Bunde T, Kirchner A, Hoffmeister B, Habedank D, Hetzer R, Cherepnev G, Proesch S, Reinke P, Volk HD, Lehmkuhl H, Kern F (2005). Protection from cytomegalovirus after transplantation is correlated with immediate early 1–specific CD8 T cells. J Exp Med, 201 (7), 1031-1036. , PMID: 15795239, PMCID: PMC2213133

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Mallone R, Kochik SA, Reijonen H, Carson B, Ziegler SF, Kwok WW, Nepom GT (2005). Functional avidity directs T-cell fate in autoreactive CD4+ T-cells. Blood, 106 (8), 2798-2805. , PMID: 16030184, PMCID: PMC1895305

Muthukumar T, Dadhania D, Ding R, Snopkowski C, Nagvi R, Lee JB, Hartono C, Li B, Sharma VK, Seshan SV, Kapur S, Hancock WW, Schwartz JE, Suthanthiran M (2005). Messenger RNA for FOXP3 in the urine of renal allograft recipients. New Engl J Med, 353 (22), 2342-2351. , PMID: 16319383

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Yang J, Jaramillo A, Shi R, Kwok WW, Mohanakumar T (2004). In vivo biotinylation of the major histo-compatibility complex (MHC) class II/peptide complex by co-expression of BirA enzyme for the generation of MHC class II/tetramers. Hum Immunol, 65 (7), 692-699. , PMID: 15301857

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Review & Commentary

Renz H, Allen KJ, Sicherer SH, Sampson HA, Lack G, Beyer K, Oettgen HC (2018). Food allergy. Nat Rev Dis Primers, 4 (4), 17098. http://dx.doi.org/10.1038/nrdp.2017.98, PMID: 29300005

Newell KA, Turka LA, Adams AB (2018). Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients.. Hum Immunol., 79 (5), 380-387. http://dx.doi.org/10.1016/j.humimm.2018.02.007, PMID: 29448053, PMCID: PMC5924709

Burks AW, Sampson HA, Plaut M, Lack G, Akdis C (2018). Treatment for food allergy. J Allergy Clin Immunol, 141 (1), 1-9. http://dx.doi.org/10.1016/j.jaci.2017.11.004, PMID: 29307409

Sampson HA, O'Mahony, L. Burks, AW. Plaut, M. Lack, Akdis CA (2018). Mechanisms of food allergy. J Allergy Clin Immunol, 141 (1), 11-19. http://dx.doi.org/10.1016/j.jaci.2017.11.005, PMID: 29307410

Sykes M (2018). Immune monitoring of transplant patients in transient mixed chimerism tolerance trials. Hum Immunol, 79 (5), 334-342. http://dx.doi.org/10.1016/j.humimm.2017.12.011, PMID: 29289741, PMCID: PMC5924718

Fisher HR, Du Toit G, Bahnson HT, Lack G (2018). The challenges of preventing food allergy: Lessons learned from LEAP and EAT. Ann Allergy Asthma Immunol, 121 (3), 313-319. http://dx.doi.org/10.1016/j.anai.2018.06.008, PMID: 29909054

Hemmings O, Kwok M, McKendry R, Santos AF (2018). Basophil Activation Test: Old and New Applications in Allergy. Current Allergy and Asthma Reports, 18 (77). http://dx.doi.org/10.1007/s11882-018-0831-5, PMID: 30430289

Wang J, Lack G (2017). Food Allergy: Unmet Needs and New Perspectives. J Allergy Clin Immunol Pract, 5 (2), 295. http://dx.doi.org/10.1016/j.jaip.2017.01.002, PMID: 28283155

Bahnson HT, Du Toit G, Lack G (2017). Statistical Considerations of Food Allergy Prevention Studies. J Allergy Clin Immunol Pract, 5 (2), 274-82. http://dx.doi.org/10.1016/j.jaip.2016.12.007, PMID: 28283152

Nepom GT, Ramsey BW, Lonial S (2017). Academic, Foundation, and Industry Collaboration in Finding New Therapies. N Engl J Med, 376 (18), 1762-9. http://dx.doi.org/10.1056/NEJMra1612575, PMID: 28467868

Kean LS, Turka LA, Blazar BR (2017). Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy. Immunol Rev, 276 (1), 192-212. http://dx.doi.org/10.1111/imr.12523, PMID: 28258702, PMCID: PMC5338458

Lawson K, Bahnson HT, Sever M, Du Toit G, Lack G, Brittain E, Keet C, Greenhawt M, Fleischer D, Chan ES, Venter C, Stukus D, Gupta R, Spergel J (2017). Letter of response to Greenhawt et al. 'LEAPing Through the Looking Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction on Peanut Tolerance after Early Peanut Introduction'. Allergy, 72 (8), 1267-71. http://dx.doi.org/10.1111/all.13127, PMID: 28691223

Nepom GT, Scott D (2017). Looking behind the data curtain. Cell Immunol. http://dx.doi.org/10.1016/j.cellimm.2017.07.008, PMID: 28754194

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Wofsy D, Diamond B, Houssiau FA (2015). Crossing the Atlantic: the Euro-Lupus Nephritis regimen in North America. Arthritis Rheumatol, 67 (5), 1144-6. http://dx.doi.org/10.1002/art.39067, PMID: 25779381, PMCID: PMC4523131

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