Publications
Articles
Antithymocyte globulin therapy for patients with recent-onset type 1 diabetes: 2 year results of a randomised trial
(2016). Diabetologia, 59 (6), 1153-61. http://dx.doi.org/10.1007/s00125-016-3917-4, PMID: 27053235, PMCID: PMC4869699
Gitelman SE, Gottlieb PA, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Harris KM, Kanaparthi S, Phippard D, Ding L, Bluestone JA, Ehlers MR; ITN START Study Team
[Reprint] [PubMed]
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Gitelman SE, Gottlieb PA, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Harris KM, Kanaparthi S, Phippard D, Ding L, Bluestone JA, Ehlers MR; ITN START Study Team (2016). Antithymocyte globulin therapy for patients with recent-onset type 1 diabetes: 2 year results of a randomised trial. Diabetologia, 59 (6), 1153-61.
Correlation Among Hypoglycemia, Glycemic Variability, and C-Peptide Preservation After Alefacept Therapy in Patients with Type 1 Diabetes Mellitus: Analysis of Data from the Immune Tolerance Network T1DAL Trial
(2016). Clin Ther, 38 (6), 1327-39. http://dx.doi.org/10.1016/j.clinthera.2016.04.032, PMID: 27209482, PMCID: PMC4916002
Pinckney A, Rigby MR, Keyes-Elstein L, Soppe CL, Nepom GT, Ehlers MR
[Reprint] [PubMed]
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Pinckney A, Rigby MR, Keyes-Elstein L, Soppe CL, Nepom GT, Ehlers MR (2016). Correlation Among Hypoglycemia, Glycemic Variability, and C-Peptide Preservation After Alefacept Therapy in Patients with Type 1 Diabetes Mellitus: Analysis of Data from the Immune Tolerance Network T1DAL Trial. Clin Ther, 38 (6), 1327-39.
Impact of peanut consumption in the LEAP Study: Feasibility, growth, and nutrition
(2016). J Allergy Clin Immunol, pii: S0091-6749 (16), 30262-7. http://dx.doi.org/10.1016/j.jaci.2016.04.016, PMID: 27297994, PMCID: PMC5056823
Feeney M, Du Toit G, Roberts G, Sayre PH, Lawson K, Bahnson HT, Sever ML, Radulovic S, Plaut M, Lack G, Immune Tolerance Network LEAP Study Team
[Reprint] [PubMed]
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Feeney M, Du Toit G, Roberts G, Sayre PH, Lawson K, Bahnson HT, Sever ML, Radulovic S, Plaut M, Lack G, Immune Tolerance Network LEAP Study Team (2016). Impact of peanut consumption in the LEAP Study: Feasibility, growth, and nutrition . J Allergy Clin Immunol, pii: S0091-6749 (16), 30262-7.
International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials
(2016). Cytotherapy, 18 (2), 151-9. http://dx.doi.org/10.1016/j.jcyt.2015.11.008, PMID: 26724220, PMCID: PMC4745114
Galipeau J, Krampera M, Barrett J, Dazzi F, Deans RJ, DeBruijn J, Dominici M, Fibbe WE, Gee AP, Gimble JM, Hematti P, Koh MB, LeBlanc K, Martin I, McNiece IK, Mendicino M, Oh S, Ortiz L, Phinney DG, Planat V, Shi Y, Stroncek DF, Viswanathan S, Weiss DJ, Sensebe L
[Reprint] [PubMed]
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Galipeau J, Krampera M, Barrett J, Dazzi F, Deans RJ, DeBruijn J, Dominici M, Fibbe WE, Gee AP, Gimble JM, Hematti P, Koh MB, LeBlanc K, Martin I, McNiece IK, Mendicino M, Oh S, Ortiz L, Phinney DG, Planat V, Shi Y, Stroncek DF, Viswanathan S, Weiss DJ, Sensebe L (2016). International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials. Cytotherapy, 18 (2), 151-9.
Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes
(2016). Science Immunology, 1 (5), pii: eaai7793. http://dx.doi.org/10.1126/sciimmunol.aai7793, PMID: 28664195, PMCID: PMC5486405
Long SA, Harris KM, Ehlers M, Herold KC, Nepom GT, Jerill Thorpe J, DeBerg HA, Gersuk V, Eddy JA, Linsley PS
[Reprint] [PubMed]
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Long SA, Harris KM, Ehlers M, Herold KC, Nepom GT, Jerill Thorpe J, DeBerg HA, Gersuk V, Eddy JA, Linsley PS (2016). Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes. Science Immunology, 1 (5), pii: eaai7793.
A role for plasma cell targeting agents in immune tolerance induction in autoimmune disease and antibody responses to therapeutic proteins
(2016). Clin Immunol, 165 (April 2016), 55-9. http://dx.doi.org/10.1016/j.clim.2016.02.009, PMID: 26928739
Diamond B, Turka LA, Rosenberg AS, Pariser AR, Yao L, Lacana E, Kishnani PS
[Reprint] [PubMed]
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Diamond B, Turka LA, Rosenberg AS, Pariser AR, Yao L, Lacana E, Kishnani PS (2016). A role for plasma cell targeting agents in immune tolerance induction in autoimmune disease and antibody responses to therapeutic proteins. Clin Immunol, 165 (April 2016), 55-9.
Myeloperoxidase-Antineutrophil Cytoplasmic Antibody (ANCA)-Positive and ANCA-Negative Patients With Granulomatosis With Polyangiitis (Wegener's): Distinct Patient Subsets
(2016). Arthritis Rheumatol, 68 (12), 2945-52. http://dx.doi.org/10.1002/art.39812, PMID: 27428559, PMCID: PMC5541999
Miloslavsky EM, Lu N, Unizony S, Choi HK, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Fervenza F, Monach PA, Specks U, Stone JH
[Reprint] [PubMed]
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Miloslavsky EM, Lu N, Unizony S, Choi HK, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Fervenza F, Monach PA, Specks U, Stone JH (2016). Myeloperoxidase-Antineutrophil Cytoplasmic Antibody (ANCA)-Positive and ANCA-Negative Patients With Granulomatosis With Polyangiitis (Wegener's): Distinct Patient Subsets. Arthritis Rheumatol, 68 (12), 2945-52.
High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for relapsing-remitting multiple sclerosis (HALT-MS): A 3-year interim report
(2015). JAMA Neurology, 72 (2), 159-69. http://dx.doi.org/10.1001/jamaneurol.2014.3780, PMID: 25546364, PMCID: PMC5261862
Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stüve O, Arnold DL, Spychala ME, McConville KC, Harris KM, Phippard D, Georges GE, Wundes A, Kraft GH, Bowen JD
[Reprint] [PubMed]
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Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stüve O, Arnold DL, Spychala ME, McConville KC, Harris KM, Phippard D, Georges GE, Wundes A, Kraft GH, Bowen JD (2015). High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for relapsing-remitting multiple sclerosis (HALT-MS): A 3-year interim report. JAMA Neurology, 72 (2), 159-69.
Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients
(2015). Sci Transl Med, 7 (272), 272ra10. http://dx.doi.org/10.1126/scitranslmed.3010760, PMID: 25632034, PMCID: PMC4360892
Morris H, DeWolf S, Robins H, Sprangers B, LoCascio SA, Shonts BA, Kawai T, Wong W, Yang S, Zuber J, Shen Y, Sykes M
[Reprint] [PubMed]
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Morris H, DeWolf S, Robins H, Sprangers B, LoCascio SA, Shonts BA, Kawai T, Wong W, Yang S, Zuber J, Shen Y, Sykes M (2015). Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients. Sci Transl Med, 7 (272), 272ra10.
Randomized trial of peanut consumption in infants at risk for peanut allergy
(2015). N Engl J Med, 372 (9), 803-813. http://dx.doi.org/10.1056/NEJMoa1414850, PMID: 25705822, PMCID: PMC4416404
Du Toit G, Roberts G, Sayre PH, Bahnson HT, Radulovic S, Santos AF, Brough HA, Phippard D, Basting M, Feeney M, Turcanu V, Sever ML, Gomez Lorenzo M, Plaut M, Lack G; LEAP Study Team
[Reprint] [PubMed]
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Du Toit G, Roberts G, Sayre PH, Bahnson HT, Radulovic S, Santos AF, Brough HA, Phippard D, Basting M, Feeney M, Turcanu V, Sever ML, Gomez Lorenzo M, Plaut M, Lack G; LEAP Study Team (2015). Randomized trial of peanut consumption in infants at risk for peanut allergy. N Engl J Med, 372 (9), 803-813.
Peripheral CD5+ B-cells in antineutrophil cytoplasmic antibody-associated vasculitis
(2015). Arthritis Rheumatol, 67 (2), 535-44. http://dx.doi.org/10.1002/art.38916, PMID: 25332071, PMCID: PMC4497572
Unizony S, Lim N, Phippard DJ, Carey VJ, Miloslavsky EM, Tchao NK, Ikle D, Asare AL, Merkel PA, Monach PA, Seo P, St Clair EW, Langford CA, Spiera R, Hoffman GS, Kallenberg CG, Specks U, Stone JH.
[Reprint] [PubMed]
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Unizony S, Lim N, Phippard DJ, Carey VJ, Miloslavsky EM, Tchao NK, Ikle D, Asare AL, Merkel PA, Monach PA, Seo P, St Clair EW, Langford CA, Spiera R, Hoffman GS, Kallenberg CG, Specks U, Stone JH. (2015). Peripheral CD5+ B-cells in antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheumatol, 67 (2), 535-44.
Effector cell signature in peripheral blood following nasal allergen challenge in grass pollen allergic individuals
(2015). Allergy, 70 (2), 171-9. http://dx.doi.org/10.1111/all.12543, PMID: 25377909
Shamji MH, Bellido V, Scadding GW, Layhadi JA, Cheung DK, Calderon MA, Asare A, Gao Z, Turka LA, Tchao N, Togias A, Phippard D, Durham SR.
[Reprint] [PubMed]
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Shamji MH, Bellido V, Scadding GW, Layhadi JA, Cheung DK, Calderon MA, Asare A, Gao Z, Turka LA, Tchao N, Togias A, Phippard D, Durham SR. (2015). Effector cell signature in peripheral blood following nasal allergen challenge in grass pollen allergic individuals. Allergy, 70 (2), 171-9.
Basophil expression of diamine oxidase: a novel biomarker of allergen immunotherapy response
(2015). J Allergy Clin Immunol, 135 (4), 913-21. http://dx.doi.org/10.1016/j.jaci.2014.09.049, PMID: 25457150
Shamji MH, Layhadi JA, Scadding GW, Cheung DK, Calderon MA, Turka LA, Phippard D, Durham SR
[Reprint] [PubMed]
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Shamji MH, Layhadi JA, Scadding GW, Cheung DK, Calderon MA, Turka LA, Phippard D, Durham SR (2015). Basophil expression of diamine oxidase: a novel biomarker of allergen immunotherapy response. J Allergy Clin Immunol, 135 (4), 913-21.
Local and systemic effects of cat allergen nasal provocation
(2015). Clin Exp Allergy, 45 (3), 613-23. http://dx.doi.org/10.1111/cea.12434, PMID: 25303516, PMCID: PMC4778413
Scadding GW, Eifan A, Penagos M, Dumitru A, Switzer A, McMahon O, Phippard D, Togias A, Durham SR, Shamji MH
[Reprint] [PubMed]
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Scadding GW, Eifan A, Penagos M, Dumitru A, Switzer A, McMahon O, Phippard D, Togias A, Durham SR, Shamji MH (2015). Local and systemic effects of cat allergen nasal provocation. Clin Exp Allergy, 45 (3), 613-23.
An interactive web application for the dissemination of human systems immunology data
(2015). J Transl Med, 19 (13), 196. http://dx.doi.org/10.1186/s12967-015-0541-x, PMID: 26088622, PMCID: PMC4474328
Speake C, Presnell S, Domico K, Zeitner B, Bjork A, Anderson D, Mason MJ, Whalen E, Vargas O, Popov D, Rinchai D, Jourde-Chiche N, Chiche L, Quinn C, Chaussabel D
[Reprint] [PubMed]
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Speake C, Presnell S, Domico K, Zeitner B, Bjork A, Anderson D, Mason MJ, Whalen E, Vargas O, Popov D, Rinchai D, Jourde-Chiche N, Chiche L, Quinn C, Chaussabel D (2015). An interactive web application for the dissemination of human systems immunology data. J Transl Med, 19 (13), 196.
Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients
(2015). J Clin Invest, 125 (8), 3285-96. http://dx.doi.org/10.1172/JCI81722, PMID: 26193635, PMCID: PMC4623571
Mark R. Rigby, Kristina M. Harris, Ashley Pinckney, Linda A. DiMeglio, Marc S. Rendell, Eric I. Felner, Jean M. Dostou, Stephen E. Gitelman, Kurt J. Griffin, Eva Tsalikian, Peter A. Gottlieb, Carla J. Greenbaum, Nicole A. Sherry, Wayne V. Moore, Roshanak Monzavi, Steven M. Willi, Philip Raskin, Lynette Keyes-Elstein, S. Alice Long, Sai Kanaparthi, Noha Lim, Deborah Phippard, Carol L. Soppe, Margret L. Fitzgibbon, James McNamara, Gerald T. Nepom, Mario R. Ehlers, Immune Tolerance Network T1DAL Study Group
[Reprint] [PubMed]
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Mark R. Rigby, Kristina M. Harris, Ashley Pinckney, Linda A. DiMeglio, Marc S. Rendell, Eric I. Felner, Jean M. Dostou, Stephen E. Gitelman, Kurt J. Griffin, Eva Tsalikian, Peter A. Gottlieb, Carla J. Greenbaum, Nicole A. Sherry, Wayne V. Moore, Roshanak Monzavi, Steven M. Willi, Philip Raskin, Lynette Keyes-Elstein, S. Alice Long, Sai Kanaparthi, Noha Lim, Deborah Phippard, Carol L. Soppe, Margret L. Fitzgibbon, James McNamara, Gerald T. Nepom, Mario R. Ehlers, Immune Tolerance Network T1DAL Study Group (2015). Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients. J Clin Invest, 125 (8), 3285-96.
Neutrophil-Related Gene Expression and Low-Density Granulocytes Associated With Disease Activity and Response to Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
(2015). Arthritis Rheumatol, 67 (7), 1922-32. http://dx.doi.org/10.1002/art.39153, PMID: 25891759, PMCID: PMC4485551
Grayson PC, Carmona-Rivera C, Xu L, Lim N, Gao Z, Asare AL, Specks U, Stone JH, Seo P, Spiera RF, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Ytterberg SR, Phippard DJ, Merkel PA, Kaplan MJ, Monach PA; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group
[Reprint] [PubMed]
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Grayson PC, Carmona-Rivera C, Xu L, Lim N, Gao Z, Asare AL, Specks U, Stone JH, Seo P, Spiera RF, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Ytterberg SR, Phippard DJ, Merkel PA, Kaplan MJ, Monach PA; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group (2015). Neutrophil-Related Gene Expression and Low-Density Granulocytes Associated With Disease Activity and Response to Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 67 (7), 1922-32.
Longitudinal Studies of a B Cell-Derived Signature of Tolerance in Renal Transplant Recipients
(2015). Am J Transplant, 15 (11), 2908-20. http://dx.doi.org/10.1111/ajt.13480, PMID: 26461968, PMCID: PMC4725587
Newell KA, Asare A, Sanz I, Wei C, Rosenberg A, Gao Z, Kanaparthi S, Asare S, Lim N, Stahly M, Howell M, Knechtle S, Kirk A, Marks WH, Kawai T, Spitzer T, Tolkoff-Rubin N, Sykes M, Sachs DH, Cosimi AB, Burlingham WJ, Phippard D, Turka LA
[Reprint] [PubMed]
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Newell KA, Asare A, Sanz I, Wei C, Rosenberg A, Gao Z, Kanaparthi S, Asare S, Lim N, Stahly M, Howell M, Knechtle S, Kirk A, Marks WH, Kawai T, Spitzer T, Tolkoff-Rubin N, Sykes M, Sachs DH, Cosimi AB, Burlingham WJ, Phippard D, Turka LA (2015). Longitudinal Studies of a B Cell-Derived Signature of Tolerance in Renal Transplant Recipients. Am J Transplant, 15 (11), 2908-20.
Outcomes of nonsevere relapses in antineutrophil cytoplasmic antibody-associated vasculitis treated with glucocorticoids
(2015). Arthritis Rheumatol, 67 (6), 1629-36. http://dx.doi.org/10.1002/art.39104, PMID: 25776953
Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Ding L, Ikle D, Villareal M, Lim N, Brunetta P, Fervenza FC, Monach PA, Stone JH; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group.
[Reprint] [PubMed]
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Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Ding L, Ikle D, Villareal M, Lim N, Brunetta P, Fervenza FC, Monach PA, Stone JH; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group. (2015). Outcomes of nonsevere relapses in antineutrophil cytoplasmic antibody-associated vasculitis treated with glucocorticoids. Arthritis Rheumatol, 67 (6), 1629-36.
Rituximab versus cyclophosphamide for ANCA-associated vasculitis with renal involvement
(2015). J Am Soc Nephrol, 26 (4), 796-85. http://dx.doi.org/10.1681/ASN.2014010046, PMID: 25381429, PMCID: PMC4378104
Geetha D, Specks U, Stone JH, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Fessler BJ, Ding L, Tchao NK, Ikle D, Jepson B, Brunetta P, Fervenza FC; Rituximab for ANCA-Associated Vasculitis Immune Tolerance Network Research Group.
[Reprint] [PubMed]
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Geetha D, Specks U, Stone JH, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Fessler BJ, Ding L, Tchao NK, Ikle D, Jepson B, Brunetta P, Fervenza FC; Rituximab for ANCA-Associated Vasculitis Immune Tolerance Network Research Group. (2015). Rituximab versus cyclophosphamide for ANCA-associated vasculitis with renal involvement. J Am Soc Nephrol, 26 (4), 796-85.
Effect of grass pollen immunotherapy on clinical and local immune response to nasal allergen challenge
(2015). Allergy, 70 (6), 689-96. http://dx.doi.org/10.1111/all.12608, PMID: 25773990, PMCID: PMC4826905
Scadding GW, Penagos M, Switzer A, Phippard D, Togias A, Shamji MH, Durham SR, Eifan AO, Lao-Araya M, Poon SY, Steveling E, Yan R
[Reprint] [PubMed]
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Scadding GW, Penagos M, Switzer A, Phippard D, Togias A, Shamji MH, Durham SR, Eifan AO, Lao-Araya M, Poon SY, Steveling E, Yan R (2015). Effect of grass pollen immunotherapy on clinical and local immune response to nasal allergen challenge. Allergy, 70 (6), 689-96.
Evaluation of Candidate Biomarkers of Type 1 Diabetes via the Core for Assay Validation
(2015). Biomark Insights, 10 (Suppl 4), 19-24. http://dx.doi.org/10.4137/BMI.S29697, PMID: 26462120, PMCID: PMC4589091
Speake C, Odegard JM
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Speake C, Odegard JM (2015). Evaluation of Candidate Biomarkers of Type 1 Diabetes via the Core for Assay Validation. Biomark Insights, 10 (Suppl 4), 19-24.
Posttransplant Metabolic Syndrome in the Withdrawal of Immunosuppression in Pediatric Liver Transplant Recipients (WISP-R) Pilot Trial
(2015). Am J Transplant, 15 (3), 779-85. http://dx.doi.org/10.1111/ajt.13024, PMID: 25648649, PMCID: PMC4426259
Rosenthal P, Alonso EM, Ekong UD, Lobritto SJ, Feng S, Perito ER, Mohammad S
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Rosenthal P, Alonso EM, Ekong UD, Lobritto SJ, Feng S, Perito ER, Mohammad S (2015). Posttransplant Metabolic Syndrome in the Withdrawal of Immunosuppression in Pediatric Liver Transplant Recipients (WISP-R) Pilot Trial. Am J Transplant, 15 (3), 779-85.
Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies
(2015). Genome Med, 7 (1), 90. http://dx.doi.org/10.1186/s13073-015-0211-x., PMID: 26423053, PMCID: PMC4589899
Li YR, van Setten J, Verma SS, Lu Y, Holmes MV, Gao H, Lek M, Nair N, Chandrupatla H, Chang B, Karczewski KJ, Wong C, Mohebnasab M, Mukhtar E, Phillips R, Tragante V, Hou C, Steel L, Lee T, Garifallou J, Guettouche T, Cao H, Guan W, Himes A, van Houten J, Pasquier A, Yu R, Carrigan E, Miller MB, Schladt D, Akdere A, Gonzalez A, Llyod KM, McGinn D, Michaud Z, Colasacco A, Snyder J, Thomas K, Wang T, Wu B, Alzahrani AJ, Al-Ali AK, Al-Muhanna FA, Al-Rubaish AM, Al-Mueilo S, Monos DS, Murphy B, Olthoff KM, Wijmenga C, Webster T, Kamoun M, Balasubramanian S, Lanktree MB, Oetting WS, Garcia-Pavia P, MacArthur DG, Hakonarson H, Birdwell KA, Jacobson PA, Ritchie MD, Asselbergs FW, Israni AK, Shaked A, Keating BJ, Gangasan Ai, de Bakker PIW
[Reprint] [PubMed]
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Li YR, van Setten J, Verma SS, Lu Y, Holmes MV, Gao H, Lek M, Nair N, Chandrupatla H, Chang B, Karczewski KJ, Wong C, Mohebnasab M, Mukhtar E, Phillips R, Tragante V, Hou C, Steel L, Lee T, Garifallou J, Guettouche T, Cao H, Guan W, Himes A, van Houten J, Pasquier A, Yu R, Carrigan E, Miller MB, Schladt D, Akdere A, Gonzalez A, Llyod KM, McGinn D, Michaud Z, Colasacco A, Snyder J, Thomas K, Wang T, Wu B, Alzahrani AJ, Al-Ali AK, Al-Muhanna FA, Al-Rubaish AM, Al-Mueilo S, Monos DS, Murphy B, Olthoff KM, Wijmenga C, Webster T, Kamoun M, Balasubramanian S, Lanktree MB, Oetting WS, Garcia-Pavia P, MacArthur DG, Hakonarson H, Birdwell KA, Jacobson PA, Ritchie MD, Asselbergs FW, Israni AK, Shaked A, Keating BJ, Gangasan Ai, de Bakker PIW (2015). Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies. Genome Med, 7 (1), 90.
Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients
(2015). J Autoimmun, Apr (58), 48-58. http://dx.doi.org/10.1016/j.jaut.2015.01.001, PMID: 25634360
Rosenzwajg M, Churlaud G, Mallone R, Six A, Dérian N, Chaara W, Lorenzon R, Long SA, Buckner JH, Afonso G, Pham HP, Hartemann A, Yu A, Pugliese A, Malek TR, Klatzmann D
[Reprint] [PubMed]
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Rosenzwajg M, Churlaud G, Mallone R, Six A, Dérian N, Chaara W, Lorenzon R, Long SA, Buckner JH, Afonso G, Pham HP, Hartemann A, Yu A, Pugliese A, Malek TR, Klatzmann D (2015). Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients. J Autoimmun, Apr (58), 48-58.
Type 1 diabetes immunotherapy using polyclonal regulatory T cells
(2015). Sci Transl Med, 7 (315), 315ra189. http://dx.doi.org/10.1126/scitranslmed.aad4134, PMID: 26606968, PMCID: PMC4729454
Bluestone JA, Buckner JH, Gitelman SE, Herold KC, Long SA, Rieck M, Sayre PH, Tang Q, Fitch M, Gupta S, Hellerstein MK, Lares A, Lee MR, Li K, Liu W, Masiello LM, Nguyen V, Putnam AL
[Reprint] [PubMed]
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Bluestone JA, Buckner JH, Gitelman SE, Herold KC, Long SA, Rieck M, Sayre PH, Tang Q, Fitch M, Gupta S, Hellerstein MK, Lares A, Lee MR, Li K, Liu W, Masiello LM, Nguyen V, Putnam AL (2015). Type 1 diabetes immunotherapy using polyclonal regulatory T cells. Sci Transl Med, 7 (315), 315ra189.
T cell repertoire following autologous stem cell transplantation for multiple sclerosis
(2014). J Clin Invest, 124 (3), 1168-72. http://dx.doi.org/10.1172/JCI71691, PMID: 24531550, PMCID: PMC3934160
Muraro PA, Robins H, Malhotra S, Howell M, Phippard D, Desmarais C, de Paula Alves Sousa A, Griffith LM, Lim N, Nash RA, Turka LA
[Reprint] [PubMed]
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Muraro PA, Robins H, Malhotra S, Howell M, Phippard D, Desmarais C, de Paula Alves Sousa A, Griffith LM, Lim N, Nash RA, Turka LA (2014). T cell repertoire following autologous stem cell transplantation for multiple sclerosis . J Clin Invest, 124 (3), 1168-72.
High-throughput flow cytometry data normalization for clinical trials
(2014). Cytometry A, 85 (3), 277-86. http://dx.doi.org/10.1002/cyto.a.22433, PMID: 24382714, PMCID: PMC3992339
Finak G, Jiang W, Krouse K, Wei C, Sanz I, Phippard D, Asare D, De Rosa SC, Self S, Gottardo R
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Finak G, Jiang W, Krouse K, Wei C, Sanz I, Phippard D, Asare D, De Rosa SC, Self S, Gottardo R (2014). High-throughput flow cytometry data normalization for clinical trials. Cytometry A, 85 (3), 277-86.
Rituximab for the Treatment of Relapses in antineutrophil cytoplasmic antibody-associated vasculitis
(2014). Arthritis Rheumatol, 66 (11), 3151-59. http://dx.doi.org/10.1002/art.38788, PMID: 25047592, PMCID: PMC4229846
Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St. Clair EW, Tchao NK, Viviano L, Ding L, Ikle D, Villareal M, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH; Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group
[Reprint] [PubMed]
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Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy
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Treatment of lupus nephritis with abatacept: The Abatacept and Cyclophosphamide Combination Efficacy and Safety Study
(2014). Arthritis & Rheumatology, 66 (11), 3096-104. http://dx.doi.org/10.1002/art.38790, PMID: 25403681, PMCID: PMC4528976
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The ACCESS Trial Group (2014). Treatment of lupus nephritis with abatacept: The Abatacept and Cyclophosphamide Combination Efficacy and Safety Study. Arthritis & Rheumatology, 66 (11), 3096-104.
Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression
(2014). Am J Transplant, 14 (7), 1599-1611. http://dx.doi.org/10.1111/ajt.12731, PMID: 24903438, PMCID: PMC4228952
Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman Sl, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Gao B, Wong W, Morris H, LoCascio SA, Sayre P, Shonts B, Williams WW, Colvin RB, Smith R-N, Sykes M, Cosimi AB.
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Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman Sl, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Gao B, Wong W, Morris H, LoCascio SA, Sayre P, Shonts B, Williams WW, Colvin RB, Smith R-N, Sykes M, Cosimi AB. (2014). Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression. Am J Transplant, 14 (7), 1599-1611.
Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: Immunologic effects and efficacy in NOD mice
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Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, Nepom G, Ehlers M, Staeva T, Garren H, Steinman L, Chan AC, von Herrath M (2013). Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: Immunologic effects and efficacy in NOD mice. PLoS One, 8 (2), e54712.
Estimating the ratio of CD4+ to CD8+ T cells using high-throughput sequence data
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Emerson R, Sherwood A, Desmarais C, Malhotra S, Phippard D, Robins H (2013). Estimating the ratio of CD4+ to CD8+ T cells using high-throughput sequence data. J Immunol Methods, 391 (1-2), 14-21.
Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: Metabolic and immunologic features at baseline identify a subgroup of responders
(2013). Diabetes, 62 (11), 3766-74. http://dx.doi.org/10.2337/db13-0345, PMID: 23835333, PMCID: PMC3806618
Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA, the AbATE Study Team
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Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA, the AbATE Study Team (2013). Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: Metabolic and immunologic features at baseline identify a subgroup of responders. Diabetes, 62 (11), 3766-74.
Efficacy of Remission-Induction Regimens for ANCA-Associated Vasculitis
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Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Fessler BJ, Ding L, Viviano L, Tchao NK, Phippard DJ, Asare AL, Lim N, Ikle D, Jepson B, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Mueller M, Sejismundo LP, Mieras K, Stone JH for the RAVE-ITN Research Group (2013). Efficacy of Remission-Induction Regimens for ANCA-Associated Vasculitis. N Engl J Med, 369 (5), 417-27.
Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial
(2013). Lancet Diabetes Endocrinol, 1 (4), 306-16. http://dx.doi.org/10.1016/S2213-8587(13)70065-2, PMID: 24622416
Gitelman SE, Gottlieb PA, Rigby MR, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, Ding L, Bluestone JA, Ehlers MR, the START Study Team
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Gitelman SE, Gottlieb PA, Rigby MR, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, Ding L, Bluestone JA, Ehlers MR, the START Study Team (2013). Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial. Lancet Diabetes Endocrinol, 1 (4), 306-16.
Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial
(2013). Lancet Diabetes Endocrinol, 1 (4), 284-94. http://dx.doi.org/10.1016/S2213-8587(13)70111-6, PMID: 24622414, PMCID: PMC3957186
Rigby MR, DiMeglio LA, Rendell MS, Felner E, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, Immune Tolerance Network T1DAL Study Team
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Rigby MR, DiMeglio LA, Rendell MS, Felner E, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, Immune Tolerance Network T1DAL Study Team (2013). Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Diabetes Endocrinol, 1 (4), 284-94.
Clinical Outcomes of Remission Induction Therapy for Severe Antineutrophil Cytoplasmic Antibody–Associated Vasculitis
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Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Tchao NK, Viviano L, Ding L, Sejismundo LP, Mieras K, Ikle D, Jepson B, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH, for the Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group
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Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CGM, St. Clair EW, Tchao NK, Viviano L, Ding L, Sejismundo LP, Mieras K, Ikle D, Jepson B, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh K, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Stone JH, for the Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group (2013). Clinical Outcomes of Remission Induction Therapy for Severe Antineutrophil Cytoplasmic Antibody–Associated Vasculitis. Arthritis Rheum, 65 (9), 2441-9.
Proinsulin/insulin autoantibodies measured with electrochemiluminescent assay are the earliest indicator of prediabetic islet autoimmunity
(2013). Diabetes Care, 36 (8), 2266-70. http://dx.doi.org/10.2337/dc12-2245, PMID: 23423694, PMCID: PMC3714529
Yu L, Dong F, Miao D, Fouts AR, Wenzlau JM, Steck AK
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Yu L, Dong F, Miao D, Fouts AR, Wenzlau JM, Steck AK (2013). Proinsulin/insulin autoantibodies measured with electrochemiluminescent assay are the earliest indicator of prediabetic islet autoimmunity. Diabetes Care, 36 (8), 2266-70.
Pre-existing epithelial diversity in normal human livers: A tissue-tethered cytometric analysis in portal/periportal epithelial cells
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Isse K, Lesniak A, Grama K, Maier J, Specht S, Castillo-Rama M, Lunz J, Roysam B, Michalopoulos G, Demetris AJ
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Isse K, Lesniak A, Grama K, Maier J, Specht S, Castillo-Rama M, Lunz J, Roysam B, Michalopoulos G, Demetris AJ (2013). Pre-existing epithelial diversity in normal human livers: A tissue-tethered cytometric analysis in portal/periportal epithelial cells. Hepatology, 57 (4), 1632-43.
Ancillary study management systems: a review of needs
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Nelson EK, Piehler B, Rauch A, Ramsay S, Holman D, Asare S, Asare A, Igra M
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Nelson EK, Piehler B, Rauch A, Ramsay S, Holman D, Asare S, Asare A, Igra M (2013). Ancillary study management systems: a review of needs. BMC Med Inform Decis Mak, 13 (5), 1-17.
Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants
(2012). JAMA, 307 (3), 283-93. http://dx.doi.org/10.1001/jama.2011.2014, PMID: 22253395
Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP, Rosenthal P, Alonso EM, Philogene MC, Ikle D, Poole KM, Bridges ND, Turka LA, Tchao NK
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Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP, Rosenthal P, Alonso EM, Philogene MC, Ikle D, Poole KM, Bridges ND, Turka LA, Tchao NK (2012). Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants. JAMA, 307 (3), 283-93.
Circulating angiopoietin-2 as a biomarker in ANCA-associated Vasculitis
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Monach PA, Kumpers P, Lukasz A, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Carette S, Ding L, Hoffman GS, Ikle D, Kallenberg CG, Khalidi NA, Langford CA, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Haubitz M, Merkel PA
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Monach PA, Kumpers P, Lukasz A, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Carette S, Ding L, Hoffman GS, Ikle D, Kallenberg CG, Khalidi NA, Langford CA, Seo P, St. Clair EW, Spiera R, Tchao N, Ytterberg SR, Haubitz M, Merkel PA (2012). Circulating angiopoietin-2 as a biomarker in ANCA-associated Vasculitis. PLoS One, 7 (1), e30197.
Randomized controlled trial of atorvastatin in clinically isolated syndrome
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Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Ikle D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C, Zamvil SS, ITN020AI Study Management Team, ITN STAyCIS Study Group
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Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Ikle D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C, Zamvil SS, ITN020AI Study Management Team, ITN STAyCIS Study Group (2012). Randomized controlled trial of atorvastatin in clinically isolated syndrome. Neurology, 78 (15), 1171-8.
Rapamycin/IL-2 combination therapy in Type 1 Diabetes
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Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network
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Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network (2012). Rapamycin/IL-2 combination therapy in Type 1 Diabetes. Diabetes, 61 (9), 2340-8.
Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes
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Scadding GW, Calderon MA, Bellido V, Koed GK, Nielsen NC, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA
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Scadding GW, Calderon MA, Bellido V, Koed GK, Nielsen NC, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA (2012). Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes. J Immunol Methods, 384 (1-2), 25-31.
Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study
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Du Toit G, Roberts G, Sayre PH, Plaut M, Bahnson HT, Mitchell H, Radulovic S, Chan S, Fox A, Turcanu V, Lack G
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Du Toit G, Roberts G, Sayre PH, Plaut M, Bahnson HT, Mitchell H, Radulovic S, Chan S, Fox A, Turcanu V, Lack G (2012). Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study. J Allergy Clin Immunol, 131 (1), 135-143.
QUAliFiER: An automated pipeline for quality assessment of gated flow cytometry data
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Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy
(2012). Allergy, 62 (2), 217-26. http://dx.doi.org/10.1111/j.1398-9995.2011.02745.x, PMID: 22077562
Shamji MH, Ljorring C, Francis JN, Calderon MA, Larché M, Kimber I, Frew AJ, Ipsen H, Lund K, Wurtzen PA, Durham SR
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Shamji MH, Ljorring C, Francis JN, Calderon MA, Larché M, Kimber I, Frew AJ, Ipsen H, Lund K, Wurtzen PA, Durham SR (2012). Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy. Allergy, 62 (2), 217-26.