Publications
Review & Commentary
Food allergy
(2018). Nat Rev Dis Primers, 4 (4), 17098. http://dx.doi.org/10.1038/nrdp.2017.98, PMID: 29300005
Renz H, Allen KJ, Sicherer SH, Sampson HA, Lack G, Beyer K, Oettgen HC
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Renz H, Allen KJ, Sicherer SH, Sampson HA, Lack G, Beyer K, Oettgen HC (2018). Food allergy. Nat Rev Dis Primers, 4 (4), 17098.
Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients.
(2018). Hum Immunol., 79 (5), 380-387. http://dx.doi.org/10.1016/j.humimm.2018.02.007, PMID: 29448053, PMCID: PMC5924709
Newell KA, Turka LA, Adams AB
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Newell KA, Turka LA, Adams AB (2018). Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients.. Hum Immunol., 79 (5), 380-387.
Treatment for food allergy
(2018). J Allergy Clin Immunol, 141 (1), 1-9. http://dx.doi.org/10.1016/j.jaci.2017.11.004, PMID: 29307409
Burks AW, Sampson HA, Plaut M, Lack G, Akdis C
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Burks AW, Sampson HA, Plaut M, Lack G, Akdis C (2018). Treatment for food allergy. J Allergy Clin Immunol, 141 (1), 1-9.
Mechanisms of food allergy
(2018). J Allergy Clin Immunol, 141 (1), 11-19. http://dx.doi.org/10.1016/j.jaci.2017.11.005, PMID: 29307410
Sampson HA, O'Mahony, L. Burks, AW. Plaut, M. Lack, Akdis CA
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Sampson HA, O'Mahony, L. Burks, AW. Plaut, M. Lack, Akdis CA (2018). Mechanisms of food allergy. J Allergy Clin Immunol, 141 (1), 11-19.
Immune monitoring of transplant patients in transient mixed chimerism tolerance trials
(2018). Hum Immunol, 79 (5), 334-342. http://dx.doi.org/10.1016/j.humimm.2017.12.011, PMID: 29289741, PMCID: PMC5924718
Sykes M
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Sykes M (2018). Immune monitoring of transplant patients in transient mixed chimerism tolerance trials. Hum Immunol, 79 (5), 334-342.
The challenges of preventing food allergy: Lessons learned from LEAP and EAT
(2018). Ann Allergy Asthma Immunol, 121 (3), 313-319. http://dx.doi.org/10.1016/j.anai.2018.06.008, PMID: 29909054
Fisher HR, Du Toit G, Bahnson HT, Lack G
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Fisher HR, Du Toit G, Bahnson HT, Lack G (2018). The challenges of preventing food allergy: Lessons learned from LEAP and EAT. Ann Allergy Asthma Immunol, 121 (3), 313-319.
Basophil Activation Test: Old and New Applications in Allergy
(2018). Current Allergy and Asthma Reports, 18 (77). http://dx.doi.org/10.1007/s11882-018-0831-5, PMID: 30430289
Hemmings O, Kwok M, McKendry R, Santos AF
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Hemmings O, Kwok M, McKendry R, Santos AF (2018). Basophil Activation Test: Old and New Applications in Allergy. Current Allergy and Asthma Reports, 18 (77).
Food Allergy: Unmet Needs and New Perspectives
(2017). J Allergy Clin Immunol Pract, 5 (2), 295. http://dx.doi.org/10.1016/j.jaip.2017.01.002, PMID: 28283155
Wang J, Lack G
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Wang J, Lack G (2017). Food Allergy: Unmet Needs and New Perspectives. J Allergy Clin Immunol Pract, 5 (2), 295.
Statistical Considerations of Food Allergy Prevention Studies
(2017). J Allergy Clin Immunol Pract, 5 (2), 274-82. http://dx.doi.org/10.1016/j.jaip.2016.12.007, PMID: 28283152
Bahnson HT, Du Toit G, Lack G
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Bahnson HT, Du Toit G, Lack G (2017). Statistical Considerations of Food Allergy Prevention Studies. J Allergy Clin Immunol Pract, 5 (2), 274-82.
Academic, Foundation, and Industry Collaboration in Finding New Therapies
(2017). N Engl J Med, 376 (18), 1762-9. http://dx.doi.org/10.1056/NEJMra1612575, PMID: 28467868
Nepom GT, Ramsey BW, Lonial S
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Nepom GT, Ramsey BW, Lonial S (2017). Academic, Foundation, and Industry Collaboration in Finding New Therapies. N Engl J Med, 376 (18), 1762-9.
Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy
(2017). Immunol Rev, 276 (1), 192-212. http://dx.doi.org/10.1111/imr.12523, PMID: 28258702, PMCID: PMC5338458
Kean LS, Turka LA, Blazar BR
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Kean LS, Turka LA, Blazar BR (2017). Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy. Immunol Rev, 276 (1), 192-212.
Letter of response to Greenhawt et al. 'LEAPing Through the Looking Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction on Peanut Tolerance after Early Peanut Introduction'
(2017). Allergy, 72 (8), 1267-71. http://dx.doi.org/10.1111/all.13127, PMID: 28691223
Lawson K, Bahnson HT, Sever M, Du Toit G, Lack G, Brittain E, Keet C, Greenhawt M, Fleischer D, Chan ES, Venter C, Stukus D, Gupta R, Spergel J
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Lawson K, Bahnson HT, Sever M, Du Toit G, Lack G, Brittain E, Keet C, Greenhawt M, Fleischer D, Chan ES, Venter C, Stukus D, Gupta R, Spergel J (2017). Letter of response to Greenhawt et al. 'LEAPing Through the Looking Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction on Peanut Tolerance after Early Peanut Introduction'. Allergy, 72 (8), 1267-71.
Looking behind the data curtain
(2017). Cell Immunol. http://dx.doi.org/10.1016/j.cellimm.2017.07.008, PMID: 28754194
Nepom GT, Scott D
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Nepom GT, Scott D (2017). Looking behind the data curtain. Cell Immunol.
Mechanisms of Mixed Chimerism-Based Transplant Tolerance
(2017). Trends Immunol., 38 (11), 829-43. http://dx.doi.org/10.1016/j.it.2017.07.008, PMID: 28826941, PMCID: PMC5669809
Zuber J, Sykes M
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Zuber J, Sykes M (2017). Mechanisms of Mixed Chimerism-Based Transplant Tolerance. Trends Immunol., 38 (11), 829-43.
Immune Interventions to Preserve β Cell Function in Type 1 Diabetes
(2016). J Investig Med, 64 (1), 7-13. http://dx.doi.org/10.1097/JIM.0000000000000227, PMID: 26225763, PMCID: PMC4732932
Ehlers MR
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Ehlers MR (2016). Immune Interventions to Preserve β Cell Function in Type 1 Diabetes. J Investig Med, 64 (1), 7-13.
Strategies for clinical trials in type 1 diabetes
(2016). J Autoimmun, Jul (71), 88-96. http://dx.doi.org/10.1016/j.jaut.2016.03.008, PMID: 27068279, PMCID: PMC4903883
Ehlers MR
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Ehlers MR (2016). Strategies for clinical trials in type 1 diabetes. J Autoimmun, Jul (71), 88-96.
Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes
(2016). J Autoimmun, Jul (71), 44-50. http://dx.doi.org/10.1016/j.jaut.2016.02.009, PMID: 26948997, PMCID: PMC4903876
Buckner JH, Nepom GT
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Buckner JH, Nepom GT (2016). Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes. J Autoimmun, Jul (71), 44-50.
Clinical trial data access: Opening doors with TrialShare
(2016). J Allergy Clin Immunol. http://dx.doi.org/10.1016/j.jaci.2016.05.034, PMID: 27474121
Asare AL, Carey VJ, Rotrosen D, Nepom GT
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Asare AL, Carey VJ, Rotrosen D, Nepom GT (2016). Clinical trial data access: Opening doors with TrialShare. J Allergy Clin Immunol.
Prevention of food allergy
(2016). J Allergy Clin Immunol, 137 (4), 998-1010. http://dx.doi.org/10.1016/j.jaci.2016.02.005, PMID: 27059727
Du Toit G, Lack G, Tsakok T, Lack S
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Du Toit G, Lack G, Tsakok T, Lack S (2016). Prevention of food allergy. J Allergy Clin Immunol, 137 (4), 998-1010.
Solving the puzzle of autoimmunity: critical questions
(2015). F1000Prime Rep, 3 (7), 17. http://dx.doi.org/10.12703/P7-17, PMID: 25750735, PMCID: PMC4335798
Smilek DE; St Clair EW
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Smilek DE; St Clair EW (2015). Solving the puzzle of autoimmunity: critical questions. F1000Prime Rep, 3 (7), 17.
Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation
(2015). Sci Transl Med, 7 (280), 280rv2. http://dx.doi.org/10.1126/scitranslmed.aaa6853., PMID: 25810312, PMCID: PMC4425354
McDonald-Hyman C, Turka LA, Blazar BR
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McDonald-Hyman C, Turka LA, Blazar BR (2015). Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation. Sci Transl Med, 7 (280), 280rv2.
The Road Traveled: Genomics and Biomarkers in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
(2015). Arthritis Rheumatol, 67 (7), 1700-2. http://dx.doi.org/10.1002/art.39148, PMID: 25891203
Kimberly RP
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Kimberly RP (2015). The Road Traveled: Genomics and Biomarkers in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 67 (7), 1700-2.
Targeting Memory T Cells in Type 1 Diabetes
(2015). Curr Diab Rep, 15 (11), 84. http://dx.doi.org/10.1007/s11892-015-0659-5, PMID: 26370695
Ehlers MR, Rigby MR
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Ehlers MR, Rigby MR (2015). Targeting Memory T Cells in Type 1 Diabetes. Curr Diab Rep, 15 (11), 84.
Tolerance signatures in transplant recipients
(2015). Curr Opin Organ Transplant, 20 (4), 400-5. http://dx.doi.org/10.1097/MOT.0000000000000207, PMID: 26107969, PMCID: PMC4524570
Newell KA, Turka LA
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Newell KA, Turka LA (2015). Tolerance signatures in transplant recipients. Curr Opin Organ Transplant, 20 (4), 400-5.
ABO-compatible liver allograft antibody-mediated rejection: an update
(2015). Curr Opin Organ Transplant, 20 (3), 314-24. http://dx.doi.org/10.1097/MOT.0000000000000194, PMID: 25944231, PMCID: PMC4646419
Demetris AJ, Zeevi A, O'Leary JG
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Demetris AJ, Zeevi A, O'Leary JG (2015). ABO-compatible liver allograft antibody-mediated rejection: an update. Curr Opin Organ Transplant, 20 (3), 314-24.
Is the use of epinephrine a good marker of severity of allergic reactions during oral food challenges?
(2015). J Allergy Clin Immunol Pract, 3 (3), 429-30. http://dx.doi.org/10.1016/j.jaip.2014.12.009, PMID: 25956314
Santos AF, Du Toit G, Lack G
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Santos AF, Du Toit G, Lack G (2015). Is the use of epinephrine a good marker of severity of allergic reactions during oral food challenges?. J Allergy Clin Immunol Pract, 3 (3), 429-30.
Crossing the Atlantic: the Euro-Lupus Nephritis regimen in North America
(2015). Arthritis Rheumatol, 67 (5), 1144-6. http://dx.doi.org/10.1002/art.39067, PMID: 25779381, PMCID: PMC4523131
Wofsy D, Diamond B, Houssiau FA
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Wofsy D, Diamond B, Houssiau FA (2015). Crossing the Atlantic: the Euro-Lupus Nephritis regimen in North America. Arthritis Rheumatol, 67 (5), 1144-6.
Tolerance: one transplant for life
(2014). Transplantation, 98 (2), 117-121. http://dx.doi.org/10.1097/TP.0000000000000260, PMID: 24926829, PMCID: PMC4101034
Kawai T, Leventhal J, Madsen JC, Strober S, Turka LA, Wood KJ
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Kawai T, Leventhal J, Madsen JC, Strober S, Turka LA, Wood KJ (2014). Tolerance: one transplant for life. Transplantation, 98 (2), 117-121.
Transplantation: moving to the next level
(2014). Immunol Rev, 258 (1), 5-11. http://dx.doi.org/10.1111/imr.12161, PMID: 24517422, PMCID: PMC4038030
Sykes M
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Sykes M (2014). Transplantation: moving to the next level. Immunol Rev, 258 (1), 5-11.
Immune-modulating effects of alpha-1 antitrypsin
(2014). Biol Chem., 395 (10), 1187-93. http://dx.doi.org/10.1515/hsz-2014-0161, PMID: 24854541, PMCID: PMC4237306
Ehlers MR
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Ehlers MR (2014). Immune-modulating effects of alpha-1 antitrypsin. Biol Chem., 395 (10), 1187-93.
Targeted immune interventions for type 1 diabetes: not as easy as it looks!
(2014). Curr Opin Endocrinol Diabetes Obes, 21 (4), 271-8. http://dx.doi.org/10.1097/MED.0000000000000075, PMID: 24983393, PMCID: PMC4133939
Rigby MR, Ehlers MR
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Rigby MR, Ehlers MR (2014). Targeted immune interventions for type 1 diabetes: not as easy as it looks!. Curr Opin Endocrinol Diabetes Obes, 21 (4), 271-8.
Restoring the balance: immunotherapeutic combinations for autoimmune disease
(2014). Dis Model Mech, 7 (5), 503-13. http://dx.doi.org/10.1242/dmm.015099, PMID: 24795433, PMCID: PMC4007402
Smilek DE, Ehlers MR, Nepom GT
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Smilek DE, Ehlers MR, Nepom GT (2014). Restoring the balance: immunotherapeutic combinations for autoimmune disease. Dis Model Mech, 7 (5), 503-13.
Anti-cytokine therapies in T1D: Concepts and strategies
(2013). Clin Immunol, 14 (3), 279-285. http://dx.doi.org/10.1016/j.clim.2013.02.003, PMID: 23510726, PMCID: 3700624
Nepom GT, Ehlers M, Mandrup-Poulsen T
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Nepom GT, Ehlers M, Mandrup-Poulsen T (2013). Anti-cytokine therapies in T1D: Concepts and strategies. Clin Immunol, 14 (3), 279-285.
Tolerance induction: hematopoietic chimerism
(2013). Curr Opin Organ Transplant, 18 (4), 402-407. http://dx.doi.org/10.1097/MOT.0b013e328363621d, PMID: 23838644
Kawai T, Sachs DH
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Kawai T, Sachs DH (2013). Tolerance induction: hematopoietic chimerism. Curr Opin Organ Transplant, 18 (4), 402-407.
Tissue biopsy monitoring of operational tolerance in liver allograft recipients
(2013). Curr Opin Organ Transplant, 18 (3), 345-353. http://dx.doi.org/10.1097/MOT.0b013e3283615d48, PMID: 23619515
Demetris AJ, Isse K
[PubMed]
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Demetris AJ, Isse K (2013). Tissue biopsy monitoring of operational tolerance in liver allograft recipients. Curr Opin Organ Transplant, 18 (3), 345-353.
Regulatory T-cell therapy in transplantation: moving to the clinic
(2013). Cold Spring Harb Perspect Med, 3 (11), na. http://dx.doi.org/10.1101/cshperspect.a015552, PMID: 24186492
Tang Q, Bluestone JA
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Tang Q, Bluestone JA (2013). Regulatory T-cell therapy in transplantation: moving to the clinic. Cold Spring Harb Perspect Med, 3 (11), na.
Participant-level data and the new frontier in trial transparency
(2013). N Engl J Med, 369 (5), 468-469. http://dx.doi.org/10.1056/NEJMe1307268, PMID: 23902488
Zarin D
[PubMed]
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Zarin D (2013). Participant-level data and the new frontier in trial transparency. N Engl J Med, 369 (5), 468-469.
Type 1 diabetes: primary antigen/peptide/register/trimolecular complex
(2013). Immunol Res, 55 (1-3), 270-6. http://dx.doi.org/10.1007/s12026-012-8367-6, PMID: 22956469, PMCID: PMC3936464
Sosinowski T, Eisenbarth GS
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Sosinowski T, Eisenbarth GS (2013). Type 1 diabetes: primary antigen/peptide/register/trimolecular complex. Immunol Res, 55 (1-3), 270-6.
Prophylactic use of sublingual allergen immunotherapy in high-risk children: a pilot study
(2013). J Allergy Clin Immunol., 132 (4), 991-3. http://dx.doi.org/10.1016/j.jaci.2013.04.049, PMID: 23768574
Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P
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Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P (2013). Prophylactic use of sublingual allergen immunotherapy in high-risk children: a pilot study. J Allergy Clin Immunol., 132 (4), 991-3.
HLA-mismatched renal transplantation without maintenance immunosuppression
(2013). N Engl J Med., 368 (19), 1850-2. http://dx.doi.org/10.1056/NEJMc1213779, PMID: 23656665, PMCID: PMC3760499
Kawai T, Sachs DH, Sykes M, Cosimi AB; Immune Tolerance Network
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Kawai T, Sachs DH, Sykes M, Cosimi AB; Immune Tolerance Network (2013). HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med., 368 (19), 1850-2.
Lymphodepletion and homeostatic proliferation: Implications for transplantation
(2012). Am J Transplant, 12 (5), 1079-1090. http://dx.doi.org/10.1111/j.1600-6143.2012.04008.x, PMID: 22420320
Tchao NK, Turka LA
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Tchao NK, Turka LA (2012). Lymphodepletion and homeostatic proliferation: Implications for transplantation. Am J Transplant, 12 (5), 1079-1090.
Digital transplantation pathology: combining whole slide imaging, multiplex staining and automated image analysis
(2012). Am J Transplant, 12 (1), 27-37. http://dx.doi.org/10.1111/j.1600-6143.2011.03797.x., PMID: 22053785, PMCID: 3627485
Isse K, Lesniak A, Grama K, Roysam B, Minervini MI, Demetris AJ
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Isse K, Lesniak A, Grama K, Roysam B, Minervini MI, Demetris AJ (2012). Digital transplantation pathology: combining whole slide imaging, multiplex staining and automated image analysis. Am J Transplant, 12 (1), 27-37.
Humoral autoimmunity in type 1 diabetes: prediction, significance, and detection of distinct disease subtypes
(2012). Cold Spring Harb Perspect Med, 2 (10), na. http://dx.doi.org/10.1101/cshperspect.a012831, PMID: 23028135, PMCID: PMC3475400
Pietropaolo M, Towns R, Eisenbarth GS
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Pietropaolo M, Towns R, Eisenbarth GS (2012). Humoral autoimmunity in type 1 diabetes: prediction, significance, and detection of distinct disease subtypes. Cold Spring Harb Perspect Med, 2 (10), na.
Prevention of type 1A diabetes mellitus
(2012). Endocr Pract, 18 (5), 745-749. http://dx.doi.org/10.4158/EP12080.OR, PMID: 22548954
Eisenbarth GS
[PubMed]
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Eisenbarth GS (2012). Prevention of type 1A diabetes mellitus. Endocr Pract, 18 (5), 745-749.
Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience
(2012). Rev Diabet Stud, 9 (4), 359-71. http://dx.doi.org/10.1900/RDS.2012.9.359, PMID: 23804273, PMCID: PMC3740703
Ehlers MR, Nepom GT
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Ehlers MR, Nepom GT (2012). Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience. Rev Diabet Stud, 9 (4), 359-71.
Challenges in the pursuit of immune tolerance
(2011). Immunol Rev, 241 (1), 49-62. http://dx.doi.org/10.1111/j.1600-065X.2011.01003.x, PMID: 21488889, PMCID: 3092524
Nepom GT, St. Clair EW, Turka LA
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Nepom GT, St. Clair EW, Turka LA (2011). Challenges in the pursuit of immune tolerance. Immunol Rev, 241 (1), 49-62.
Regulatory cells and cell signatures in clinical transplantation tolerance
(2011). Curr Opin Immunol, 23 (5), 655-659. http://dx.doi.org/10.1016/j.coi.2011.07.008, PMID: 21982510
Newell KA, Phippard D, Turka LA
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Newell KA, Phippard D, Turka LA (2011). Regulatory cells and cell signatures in clinical transplantation tolerance. Curr Opin Immunol, 23 (5), 655-659.
Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism
(2011). Curr Opin Organ Transplant, 16 (4), 366-371. http://dx.doi.org/10.1097/MOT.0b013e3283484b2c, PMID: 21666482, PMCID: 3151013
Kawai T, Cosimi, Sachs DH
[Reprint] [PubMed]
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Kawai T, Cosimi, Sachs DH (2011). Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism. Curr Opin Organ Transplant, 16 (4), 366-371.
Ten years of the Immune Tolerance Network: an integrated clinical research organization
(2010). Sci Transl Med, 2 (19), 1-4. http://dx.doi.org/10.1126/scitranslmed.3000672, PMID: 20371484
Bluestone JA, Krensky AM, Turka LA, Rotrosen D, Matthews JB
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Bluestone JA, Krensky AM, Turka LA, Rotrosen D, Matthews JB (2010). Ten years of the Immune Tolerance Network: an integrated clinical research organization. Sci Transl Med, 2 (19), 1-4.
Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group
(2010). Clin Exp Immunol, 160 (2), 176-184. , PMID: 20629979, PMCID: 2857940
Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, ITN/JDRF Type 1 Diabetes Combination Therapy Assessment Group
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Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, ITN/JDRF Type 1 Diabetes Combination Therapy Assessment Group (2010). Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group. Clin Exp Immunol, 160 (2), 176-184.