Publications
Review & Commentary
Mechanisms of food allergy
(2018). J Allergy Clin Immunol, 141 (1), 11-19. http://dx.doi.org/10.1016/j.jaci.2017.11.005, PMID: 29307410
Sampson HA, O'Mahony, L. Burks, AW. Plaut, M. Lack, Akdis CA
[Reprint] [PubMed]
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Sampson HA, O'Mahony, L. Burks, AW. Plaut, M. Lack, Akdis CA (2018). Mechanisms of food allergy. J Allergy Clin Immunol, 141 (1), 11-19.
Immune monitoring of transplant patients in transient mixed chimerism tolerance trials
(2018). Hum Immunol, 79 (5), 334-342. http://dx.doi.org/10.1016/j.humimm.2017.12.011, PMID: 29289741, PMCID: PMC5924718
Sykes M
[Reprint] [PubMed]
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Sykes M (2018). Immune monitoring of transplant patients in transient mixed chimerism tolerance trials. Hum Immunol, 79 (5), 334-342.
The challenges of preventing food allergy: Lessons learned from LEAP and EAT
(2018). Ann Allergy Asthma Immunol, 121 (3), 313-319. http://dx.doi.org/10.1016/j.anai.2018.06.008, PMID: 29909054
Fisher HR, Du Toit G, Bahnson HT, Lack G
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Fisher HR, Du Toit G, Bahnson HT, Lack G (2018). The challenges of preventing food allergy: Lessons learned from LEAP and EAT. Ann Allergy Asthma Immunol, 121 (3), 313-319.
Basophil Activation Test: Old and New Applications in Allergy
(2018). Current Allergy and Asthma Reports, 18 (77). http://dx.doi.org/10.1007/s11882-018-0831-5, PMID: 30430289
Hemmings O, Kwok M, McKendry R, Santos AF
[Reprint] [PubMed]
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Hemmings O, Kwok M, McKendry R, Santos AF (2018). Basophil Activation Test: Old and New Applications in Allergy. Current Allergy and Asthma Reports, 18 (77).
Food Allergy: Unmet Needs and New Perspectives
(2017). J Allergy Clin Immunol Pract, 5 (2), 295. http://dx.doi.org/10.1016/j.jaip.2017.01.002, PMID: 28283155
Wang J, Lack G
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Wang J, Lack G (2017). Food Allergy: Unmet Needs and New Perspectives. J Allergy Clin Immunol Pract, 5 (2), 295.
Statistical Considerations of Food Allergy Prevention Studies
(2017). J Allergy Clin Immunol Pract, 5 (2), 274-82. http://dx.doi.org/10.1016/j.jaip.2016.12.007, PMID: 28283152
Bahnson HT, Du Toit G, Lack G
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Bahnson HT, Du Toit G, Lack G (2017). Statistical Considerations of Food Allergy Prevention Studies. J Allergy Clin Immunol Pract, 5 (2), 274-82.
Academic, Foundation, and Industry Collaboration in Finding New Therapies
(2017). N Engl J Med, 376 (18), 1762-9. http://dx.doi.org/10.1056/NEJMra1612575, PMID: 28467868
Nepom GT, Ramsey BW, Lonial S
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Nepom GT, Ramsey BW, Lonial S (2017). Academic, Foundation, and Industry Collaboration in Finding New Therapies. N Engl J Med, 376 (18), 1762-9.
Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy
(2017). Immunol Rev, 276 (1), 192-212. http://dx.doi.org/10.1111/imr.12523, PMID: 28258702, PMCID: PMC5338458
Kean LS, Turka LA, Blazar BR
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Kean LS, Turka LA, Blazar BR (2017). Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy. Immunol Rev, 276 (1), 192-212.
Letter of response to Greenhawt et al. 'LEAPing Through the Looking Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction on Peanut Tolerance after Early Peanut Introduction'
(2017). Allergy, 72 (8), 1267-71. http://dx.doi.org/10.1111/all.13127, PMID: 28691223
Lawson K, Bahnson HT, Sever M, Du Toit G, Lack G, Brittain E, Keet C, Greenhawt M, Fleischer D, Chan ES, Venter C, Stukus D, Gupta R, Spergel J
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Lawson K, Bahnson HT, Sever M, Du Toit G, Lack G, Brittain E, Keet C, Greenhawt M, Fleischer D, Chan ES, Venter C, Stukus D, Gupta R, Spergel J (2017). Letter of response to Greenhawt et al. 'LEAPing Through the Looking Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction on Peanut Tolerance after Early Peanut Introduction'. Allergy, 72 (8), 1267-71.
Looking behind the data curtain
(2017). Cell Immunol. http://dx.doi.org/10.1016/j.cellimm.2017.07.008, PMID: 28754194
Nepom GT, Scott D
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Nepom GT, Scott D (2017). Looking behind the data curtain. Cell Immunol.
Mechanisms of Mixed Chimerism-Based Transplant Tolerance
(2017). Trends Immunol., 38 (11), 829-43. http://dx.doi.org/10.1016/j.it.2017.07.008, PMID: 28826941, PMCID: PMC5669809
Zuber J, Sykes M
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Zuber J, Sykes M (2017). Mechanisms of Mixed Chimerism-Based Transplant Tolerance. Trends Immunol., 38 (11), 829-43.
Immune Interventions to Preserve β Cell Function in Type 1 Diabetes
(2016). J Investig Med, 64 (1), 7-13. http://dx.doi.org/10.1097/JIM.0000000000000227, PMID: 26225763, PMCID: PMC4732932
Ehlers MR
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Ehlers MR (2016). Immune Interventions to Preserve β Cell Function in Type 1 Diabetes. J Investig Med, 64 (1), 7-13.
Strategies for clinical trials in type 1 diabetes
(2016). J Autoimmun, Jul (71), 88-96. http://dx.doi.org/10.1016/j.jaut.2016.03.008, PMID: 27068279, PMCID: PMC4903883
Ehlers MR
[Reprint] [PubMed]
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Ehlers MR (2016). Strategies for clinical trials in type 1 diabetes. J Autoimmun, Jul (71), 88-96.
Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes
(2016). J Autoimmun, Jul (71), 44-50. http://dx.doi.org/10.1016/j.jaut.2016.02.009, PMID: 26948997, PMCID: PMC4903876
Buckner JH, Nepom GT
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Buckner JH, Nepom GT (2016). Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes. J Autoimmun, Jul (71), 44-50.
Clinical trial data access: Opening doors with TrialShare
(2016). J Allergy Clin Immunol. http://dx.doi.org/10.1016/j.jaci.2016.05.034, PMID: 27474121
Asare AL, Carey VJ, Rotrosen D, Nepom GT
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Asare AL, Carey VJ, Rotrosen D, Nepom GT (2016). Clinical trial data access: Opening doors with TrialShare. J Allergy Clin Immunol.
Prevention of food allergy
(2016). J Allergy Clin Immunol, 137 (4), 998-1010. http://dx.doi.org/10.1016/j.jaci.2016.02.005, PMID: 27059727
Du Toit G, Lack G, Tsakok T, Lack S
[Reprint] [PubMed]
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Du Toit G, Lack G, Tsakok T, Lack S (2016). Prevention of food allergy. J Allergy Clin Immunol, 137 (4), 998-1010.
Solving the puzzle of autoimmunity: critical questions
(2015). F1000Prime Rep, 3 (7), 17. http://dx.doi.org/10.12703/P7-17, PMID: 25750735, PMCID: PMC4335798
Smilek DE; St Clair EW
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Smilek DE; St Clair EW (2015). Solving the puzzle of autoimmunity: critical questions. F1000Prime Rep, 3 (7), 17.
Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation
(2015). Sci Transl Med, 7 (280), 280rv2. http://dx.doi.org/10.1126/scitranslmed.aaa6853., PMID: 25810312, PMCID: PMC4425354
McDonald-Hyman C, Turka LA, Blazar BR
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McDonald-Hyman C, Turka LA, Blazar BR (2015). Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation. Sci Transl Med, 7 (280), 280rv2.
The Road Traveled: Genomics and Biomarkers in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
(2015). Arthritis Rheumatol, 67 (7), 1700-2. http://dx.doi.org/10.1002/art.39148, PMID: 25891203
Kimberly RP
[Reprint] [PubMed]
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Kimberly RP (2015). The Road Traveled: Genomics and Biomarkers in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 67 (7), 1700-2.
Targeting Memory T Cells in Type 1 Diabetes
(2015). Curr Diab Rep, 15 (11), 84. http://dx.doi.org/10.1007/s11892-015-0659-5, PMID: 26370695
Ehlers MR, Rigby MR
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Ehlers MR, Rigby MR (2015). Targeting Memory T Cells in Type 1 Diabetes. Curr Diab Rep, 15 (11), 84.
Tolerance signatures in transplant recipients
(2015). Curr Opin Organ Transplant, 20 (4), 400-5. http://dx.doi.org/10.1097/MOT.0000000000000207, PMID: 26107969, PMCID: PMC4524570
Newell KA, Turka LA
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Newell KA, Turka LA (2015). Tolerance signatures in transplant recipients. Curr Opin Organ Transplant, 20 (4), 400-5.
ABO-compatible liver allograft antibody-mediated rejection: an update
(2015). Curr Opin Organ Transplant, 20 (3), 314-24. http://dx.doi.org/10.1097/MOT.0000000000000194, PMID: 25944231, PMCID: PMC4646419
Demetris AJ, Zeevi A, O'Leary JG
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Demetris AJ, Zeevi A, O'Leary JG (2015). ABO-compatible liver allograft antibody-mediated rejection: an update. Curr Opin Organ Transplant, 20 (3), 314-24.
Is the use of epinephrine a good marker of severity of allergic reactions during oral food challenges?
(2015). J Allergy Clin Immunol Pract, 3 (3), 429-30. http://dx.doi.org/10.1016/j.jaip.2014.12.009, PMID: 25956314
Santos AF, Du Toit G, Lack G
[Reprint] [PubMed]
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Santos AF, Du Toit G, Lack G (2015). Is the use of epinephrine a good marker of severity of allergic reactions during oral food challenges?. J Allergy Clin Immunol Pract, 3 (3), 429-30.
Crossing the Atlantic: the Euro-Lupus Nephritis regimen in North America
(2015). Arthritis Rheumatol, 67 (5), 1144-6. http://dx.doi.org/10.1002/art.39067, PMID: 25779381, PMCID: PMC4523131
Wofsy D, Diamond B, Houssiau FA
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Wofsy D, Diamond B, Houssiau FA (2015). Crossing the Atlantic: the Euro-Lupus Nephritis regimen in North America. Arthritis Rheumatol, 67 (5), 1144-6.
Tolerance: one transplant for life
(2014). Transplantation, 98 (2), 117-121. http://dx.doi.org/10.1097/TP.0000000000000260, PMID: 24926829, PMCID: PMC4101034
Kawai T, Leventhal J, Madsen JC, Strober S, Turka LA, Wood KJ
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Kawai T, Leventhal J, Madsen JC, Strober S, Turka LA, Wood KJ (2014). Tolerance: one transplant for life. Transplantation, 98 (2), 117-121.
Transplantation: moving to the next level
(2014). Immunol Rev, 258 (1), 5-11. http://dx.doi.org/10.1111/imr.12161, PMID: 24517422, PMCID: PMC4038030
Sykes M
[Reprint] [PubMed]
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Sykes M (2014). Transplantation: moving to the next level. Immunol Rev, 258 (1), 5-11.
Immune-modulating effects of alpha-1 antitrypsin
(2014). Biol Chem., 395 (10), 1187-93. http://dx.doi.org/10.1515/hsz-2014-0161, PMID: 24854541, PMCID: PMC4237306
Ehlers MR
[Reprint] [PubMed]
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Ehlers MR (2014). Immune-modulating effects of alpha-1 antitrypsin. Biol Chem., 395 (10), 1187-93.
Targeted immune interventions for type 1 diabetes: not as easy as it looks!
(2014). Curr Opin Endocrinol Diabetes Obes, 21 (4), 271-8. http://dx.doi.org/10.1097/MED.0000000000000075, PMID: 24983393, PMCID: PMC4133939
Rigby MR, Ehlers MR
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Rigby MR, Ehlers MR (2014). Targeted immune interventions for type 1 diabetes: not as easy as it looks!. Curr Opin Endocrinol Diabetes Obes, 21 (4), 271-8.
Restoring the balance: immunotherapeutic combinations for autoimmune disease
(2014). Dis Model Mech, 7 (5), 503-13. http://dx.doi.org/10.1242/dmm.015099, PMID: 24795433, PMCID: PMC4007402
Smilek DE, Ehlers MR, Nepom GT
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Smilek DE, Ehlers MR, Nepom GT (2014). Restoring the balance: immunotherapeutic combinations for autoimmune disease. Dis Model Mech, 7 (5), 503-13.
Anti-cytokine therapies in T1D: Concepts and strategies
(2013). Clin Immunol, 14 (3), 279-285. http://dx.doi.org/10.1016/j.clim.2013.02.003, PMID: 23510726, PMCID: 3700624
Nepom GT, Ehlers M, Mandrup-Poulsen T
[PubMed]
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Nepom GT, Ehlers M, Mandrup-Poulsen T (2013). Anti-cytokine therapies in T1D: Concepts and strategies. Clin Immunol, 14 (3), 279-285.
Tolerance induction: hematopoietic chimerism
(2013). Curr Opin Organ Transplant, 18 (4), 402-407. http://dx.doi.org/10.1097/MOT.0b013e328363621d, PMID: 23838644
Kawai T, Sachs DH
[PubMed]
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Kawai T, Sachs DH (2013). Tolerance induction: hematopoietic chimerism. Curr Opin Organ Transplant, 18 (4), 402-407.
Tissue biopsy monitoring of operational tolerance in liver allograft recipients
(2013). Curr Opin Organ Transplant, 18 (3), 345-353. http://dx.doi.org/10.1097/MOT.0b013e3283615d48, PMID: 23619515
Demetris AJ, Isse K
[PubMed]
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Demetris AJ, Isse K (2013). Tissue biopsy monitoring of operational tolerance in liver allograft recipients. Curr Opin Organ Transplant, 18 (3), 345-353.
Regulatory T-cell therapy in transplantation: moving to the clinic
(2013). Cold Spring Harb Perspect Med, 3 (11), na. http://dx.doi.org/10.1101/cshperspect.a015552, PMID: 24186492
Tang Q, Bluestone JA
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Tang Q, Bluestone JA (2013). Regulatory T-cell therapy in transplantation: moving to the clinic. Cold Spring Harb Perspect Med, 3 (11), na.
Participant-level data and the new frontier in trial transparency
(2013). N Engl J Med, 369 (5), 468-469. http://dx.doi.org/10.1056/NEJMe1307268, PMID: 23902488
Zarin D
[PubMed]
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Zarin D (2013). Participant-level data and the new frontier in trial transparency. N Engl J Med, 369 (5), 468-469.
Type 1 diabetes: primary antigen/peptide/register/trimolecular complex
(2013). Immunol Res, 55 (1-3), 270-6. http://dx.doi.org/10.1007/s12026-012-8367-6, PMID: 22956469, PMCID: PMC3936464
Sosinowski T, Eisenbarth GS
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Sosinowski T, Eisenbarth GS (2013). Type 1 diabetes: primary antigen/peptide/register/trimolecular complex. Immunol Res, 55 (1-3), 270-6.
Prophylactic use of sublingual allergen immunotherapy in high-risk children: a pilot study
(2013). J Allergy Clin Immunol., 132 (4), 991-3. http://dx.doi.org/10.1016/j.jaci.2013.04.049, PMID: 23768574
Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P
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Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P (2013). Prophylactic use of sublingual allergen immunotherapy in high-risk children: a pilot study. J Allergy Clin Immunol., 132 (4), 991-3.
HLA-mismatched renal transplantation without maintenance immunosuppression
(2013). N Engl J Med., 368 (19), 1850-2. http://dx.doi.org/10.1056/NEJMc1213779, PMID: 23656665, PMCID: PMC3760499
Kawai T, Sachs DH, Sykes M, Cosimi AB; Immune Tolerance Network
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Kawai T, Sachs DH, Sykes M, Cosimi AB; Immune Tolerance Network (2013). HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med., 368 (19), 1850-2.
Lymphodepletion and homeostatic proliferation: Implications for transplantation
(2012). Am J Transplant, 12 (5), 1079-1090. http://dx.doi.org/10.1111/j.1600-6143.2012.04008.x, PMID: 22420320
Tchao NK, Turka LA
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Tchao NK, Turka LA (2012). Lymphodepletion and homeostatic proliferation: Implications for transplantation. Am J Transplant, 12 (5), 1079-1090.
Digital transplantation pathology: combining whole slide imaging, multiplex staining and automated image analysis
(2012). Am J Transplant, 12 (1), 27-37. http://dx.doi.org/10.1111/j.1600-6143.2011.03797.x., PMID: 22053785, PMCID: 3627485
Isse K, Lesniak A, Grama K, Roysam B, Minervini MI, Demetris AJ
[PubMed]
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Isse K, Lesniak A, Grama K, Roysam B, Minervini MI, Demetris AJ (2012). Digital transplantation pathology: combining whole slide imaging, multiplex staining and automated image analysis. Am J Transplant, 12 (1), 27-37.
Humoral autoimmunity in type 1 diabetes: prediction, significance, and detection of distinct disease subtypes
(2012). Cold Spring Harb Perspect Med, 2 (10), na. http://dx.doi.org/10.1101/cshperspect.a012831, PMID: 23028135, PMCID: PMC3475400
Pietropaolo M, Towns R, Eisenbarth GS
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Pietropaolo M, Towns R, Eisenbarth GS (2012). Humoral autoimmunity in type 1 diabetes: prediction, significance, and detection of distinct disease subtypes. Cold Spring Harb Perspect Med, 2 (10), na.
Prevention of type 1A diabetes mellitus
(2012). Endocr Pract, 18 (5), 745-749. http://dx.doi.org/10.4158/EP12080.OR, PMID: 22548954
Eisenbarth GS
[PubMed]
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Eisenbarth GS (2012). Prevention of type 1A diabetes mellitus. Endocr Pract, 18 (5), 745-749.
Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience
(2012). Rev Diabet Stud, 9 (4), 359-71. http://dx.doi.org/10.1900/RDS.2012.9.359, PMID: 23804273, PMCID: PMC3740703
Ehlers MR, Nepom GT
[Reprint] [PubMed]
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Ehlers MR, Nepom GT (2012). Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience. Rev Diabet Stud, 9 (4), 359-71.
Challenges in the pursuit of immune tolerance
(2011). Immunol Rev, 241 (1), 49-62. http://dx.doi.org/10.1111/j.1600-065X.2011.01003.x, PMID: 21488889, PMCID: 3092524
Nepom GT, St. Clair EW, Turka LA
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Nepom GT, St. Clair EW, Turka LA (2011). Challenges in the pursuit of immune tolerance. Immunol Rev, 241 (1), 49-62.
Regulatory cells and cell signatures in clinical transplantation tolerance
(2011). Curr Opin Immunol, 23 (5), 655-659. http://dx.doi.org/10.1016/j.coi.2011.07.008, PMID: 21982510
Newell KA, Phippard D, Turka LA
[Reprint] [PubMed]
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Newell KA, Phippard D, Turka LA (2011). Regulatory cells and cell signatures in clinical transplantation tolerance. Curr Opin Immunol, 23 (5), 655-659.
Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism
(2011). Curr Opin Organ Transplant, 16 (4), 366-371. http://dx.doi.org/10.1097/MOT.0b013e3283484b2c, PMID: 21666482, PMCID: 3151013
Kawai T, Cosimi, Sachs DH
[Reprint] [PubMed]
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Kawai T, Cosimi, Sachs DH (2011). Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism. Curr Opin Organ Transplant, 16 (4), 366-371.
Ten years of the Immune Tolerance Network: an integrated clinical research organization
(2010). Sci Transl Med, 2 (19), 1-4. http://dx.doi.org/10.1126/scitranslmed.3000672, PMID: 20371484
Bluestone JA, Krensky AM, Turka LA, Rotrosen D, Matthews JB
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Bluestone JA, Krensky AM, Turka LA, Rotrosen D, Matthews JB (2010). Ten years of the Immune Tolerance Network: an integrated clinical research organization. Sci Transl Med, 2 (19), 1-4.
Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group
(2010). Clin Exp Immunol, 160 (2), 176-184. , PMID: 20629979, PMCID: 2857940
Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, ITN/JDRF Type 1 Diabetes Combination Therapy Assessment Group
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Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, ITN/JDRF Type 1 Diabetes Combination Therapy Assessment Group (2010). Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group. Clin Exp Immunol, 160 (2), 176-184.
Bringing transplantation tolerance into the clinic: lessons from the ITN and RISET for the Establishment of Tolerance consortia
(2010). Curr Opin Organ Transplant, 15 (4), 441-448. http://dx.doi.org/10.1097/MOT.0b013e32833bd371, PMID: 20631613
Turka LA, Wood K, Bluestone JA
[PubMed]
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Turka LA, Wood K, Bluestone JA (2010). Bringing transplantation tolerance into the clinic: lessons from the ITN and RISET for the Establishment of Tolerance consortia. Curr Opin Organ Transplant, 15 (4), 441-448.
Immune Tolerance Network at 10 years: Tolerance research at the bedside
(2010). Nat Rev Immunol, 10 (11), 797-803. http://dx.doi.org/10.1038/nri2869, PMID: 20972473
Bluestone JA, Auchincloss H, Nepom GT, Rotrosen D, St. Clair EW, Turka LA
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Bluestone JA, Auchincloss H, Nepom GT, Rotrosen D, St. Clair EW, Turka LA (2010). Immune Tolerance Network at 10 years: Tolerance research at the bedside. Nat Rev Immunol, 10 (11), 797-803.
Adding value to liver (and allograft) biopsy evaluation using a combination of multiplex quantum dot immunostaining, high-resolution whole-slide digital imaging, and automated image analysis
(2010). Clin Liver Dis, 14 (4), 669-685. http://dx.doi.org/10.1016/j.cld.2010.07.004, PMID: 21055689
Isse K, Grama K, Abbott IM, Lesniak A, Lunz J, Lee WM, Specht S, Corbitt N, Mizuguchi Y, Roysam B, Demetris AJG
[PubMed]
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Isse K, Grama K, Abbott IM, Lesniak A, Lunz J, Lee WM, Specht S, Corbitt N, Mizuguchi Y, Roysam B, Demetris AJG (2010). Adding value to liver (and allograft) biopsy evaluation using a combination of multiplex quantum dot immunostaining, high-resolution whole-slide digital imaging, and automated image analysis. Clin Liver Dis, 14 (4), 669-685.