Publications
Review & Commentary
Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation
(2015). Sci Transl Med, 7 (280), 280rv2. http://dx.doi.org/10.1126/scitranslmed.aaa6853., PMID: 25810312, PMCID: PMC4425354
McDonald-Hyman C, Turka LA, Blazar BR
[Reprint] [PubMed]
[Citation View]
McDonald-Hyman C, Turka LA, Blazar BR (2015). Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation. Sci Transl Med, 7 (280), 280rv2.
The Road Traveled: Genomics and Biomarkers in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
(2015). Arthritis Rheumatol, 67 (7), 1700-2. http://dx.doi.org/10.1002/art.39148, PMID: 25891203
Kimberly RP
[Reprint] [PubMed]
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Kimberly RP (2015). The Road Traveled: Genomics and Biomarkers in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 67 (7), 1700-2.
Targeting Memory T Cells in Type 1 Diabetes
(2015). Curr Diab Rep, 15 (11), 84. http://dx.doi.org/10.1007/s11892-015-0659-5, PMID: 26370695
Ehlers MR, Rigby MR
[Reprint] [PubMed]
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Ehlers MR, Rigby MR (2015). Targeting Memory T Cells in Type 1 Diabetes. Curr Diab Rep, 15 (11), 84.
Tolerance signatures in transplant recipients
(2015). Curr Opin Organ Transplant, 20 (4), 400-5. http://dx.doi.org/10.1097/MOT.0000000000000207, PMID: 26107969, PMCID: PMC4524570
Newell KA, Turka LA
[Reprint] [PubMed]
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Newell KA, Turka LA (2015). Tolerance signatures in transplant recipients. Curr Opin Organ Transplant, 20 (4), 400-5.
ABO-compatible liver allograft antibody-mediated rejection: an update
(2015). Curr Opin Organ Transplant, 20 (3), 314-24. http://dx.doi.org/10.1097/MOT.0000000000000194, PMID: 25944231, PMCID: PMC4646419
Demetris AJ, Zeevi A, O'Leary JG
[Reprint] [PubMed]
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Demetris AJ, Zeevi A, O'Leary JG (2015). ABO-compatible liver allograft antibody-mediated rejection: an update. Curr Opin Organ Transplant, 20 (3), 314-24.
Is the use of epinephrine a good marker of severity of allergic reactions during oral food challenges?
(2015). J Allergy Clin Immunol Pract, 3 (3), 429-30. http://dx.doi.org/10.1016/j.jaip.2014.12.009, PMID: 25956314
Santos AF, Du Toit G, Lack G
[Reprint] [PubMed]
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Santos AF, Du Toit G, Lack G (2015). Is the use of epinephrine a good marker of severity of allergic reactions during oral food challenges?. J Allergy Clin Immunol Pract, 3 (3), 429-30.
Crossing the Atlantic: the Euro-Lupus Nephritis regimen in North America
(2015). Arthritis Rheumatol, 67 (5), 1144-6. http://dx.doi.org/10.1002/art.39067, PMID: 25779381, PMCID: PMC4523131
Wofsy D, Diamond B, Houssiau FA
[Reprint] [PubMed]
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Wofsy D, Diamond B, Houssiau FA (2015). Crossing the Atlantic: the Euro-Lupus Nephritis regimen in North America. Arthritis Rheumatol, 67 (5), 1144-6.
Tolerance: one transplant for life
(2014). Transplantation, 98 (2), 117-121. http://dx.doi.org/10.1097/TP.0000000000000260, PMID: 24926829, PMCID: PMC4101034
Kawai T, Leventhal J, Madsen JC, Strober S, Turka LA, Wood KJ
[PubMed]
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Kawai T, Leventhal J, Madsen JC, Strober S, Turka LA, Wood KJ (2014). Tolerance: one transplant for life. Transplantation, 98 (2), 117-121.
Transplantation: moving to the next level
(2014). Immunol Rev, 258 (1), 5-11. http://dx.doi.org/10.1111/imr.12161, PMID: 24517422, PMCID: PMC4038030
Sykes M
[Reprint] [PubMed]
[Citation View]
Sykes M (2014). Transplantation: moving to the next level. Immunol Rev, 258 (1), 5-11.
Immune-modulating effects of alpha-1 antitrypsin
(2014). Biol Chem., 395 (10), 1187-93. http://dx.doi.org/10.1515/hsz-2014-0161, PMID: 24854541, PMCID: PMC4237306
Ehlers MR
[Reprint] [PubMed]
[Citation View]
Ehlers MR (2014). Immune-modulating effects of alpha-1 antitrypsin. Biol Chem., 395 (10), 1187-93.
Targeted immune interventions for type 1 diabetes: not as easy as it looks!
(2014). Curr Opin Endocrinol Diabetes Obes, 21 (4), 271-8. http://dx.doi.org/10.1097/MED.0000000000000075, PMID: 24983393, PMCID: PMC4133939
Rigby MR, Ehlers MR
[Reprint] [PubMed]
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Rigby MR, Ehlers MR (2014). Targeted immune interventions for type 1 diabetes: not as easy as it looks!. Curr Opin Endocrinol Diabetes Obes, 21 (4), 271-8.
Restoring the balance: immunotherapeutic combinations for autoimmune disease
(2014). Dis Model Mech, 7 (5), 503-13. http://dx.doi.org/10.1242/dmm.015099, PMID: 24795433, PMCID: PMC4007402
Smilek DE, Ehlers MR, Nepom GT
[Reprint] [PubMed]
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Smilek DE, Ehlers MR, Nepom GT (2014). Restoring the balance: immunotherapeutic combinations for autoimmune disease. Dis Model Mech, 7 (5), 503-13.
Anti-cytokine therapies in T1D: Concepts and strategies
(2013). Clin Immunol, 14 (3), 279-285. http://dx.doi.org/10.1016/j.clim.2013.02.003, PMID: 23510726, PMCID: 3700624
Nepom GT, Ehlers M, Mandrup-Poulsen T
[Reprint] [PubMed]
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Nepom GT, Ehlers M, Mandrup-Poulsen T (2013). Anti-cytokine therapies in T1D: Concepts and strategies. Clin Immunol, 14 (3), 279-285.
Tolerance induction: hematopoietic chimerism
(2013). Curr Opin Organ Transplant, 18 (4), 402-407. http://dx.doi.org/10.1097/MOT.0b013e328363621d, PMID: 23838644
Kawai T, Sachs DH
[PubMed]
[Citation View]
Kawai T, Sachs DH (2013). Tolerance induction: hematopoietic chimerism. Curr Opin Organ Transplant, 18 (4), 402-407.
Tissue biopsy monitoring of operational tolerance in liver allograft recipients
(2013). Curr Opin Organ Transplant, 18 (3), 345-353. http://dx.doi.org/10.1097/MOT.0b013e3283615d48, PMID: 23619515
Demetris AJ, Isse K
[PubMed]
[Citation View]
Demetris AJ, Isse K (2013). Tissue biopsy monitoring of operational tolerance in liver allograft recipients. Curr Opin Organ Transplant, 18 (3), 345-353.
Regulatory T-cell therapy in transplantation: moving to the clinic
(2013). Cold Spring Harb Perspect Med, 3 (11), na. http://dx.doi.org/10.1101/cshperspect.a015552, PMID: 24186492
Tang Q, Bluestone JA
[Reprint] [PubMed]
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Tang Q, Bluestone JA (2013). Regulatory T-cell therapy in transplantation: moving to the clinic. Cold Spring Harb Perspect Med, 3 (11), na.
Participant-level data and the new frontier in trial transparency
(2013). N Engl J Med, 369 (5), 468-469. http://dx.doi.org/10.1056/NEJMe1307268, PMID: 23902488
Zarin D
[PubMed]
[Citation View]
Zarin D (2013). Participant-level data and the new frontier in trial transparency. N Engl J Med, 369 (5), 468-469.
Type 1 diabetes: primary antigen/peptide/register/trimolecular complex
(2013). Immunol Res, 55 (1-3), 270-6. http://dx.doi.org/10.1007/s12026-012-8367-6, PMID: 22956469, PMCID: PMC3936464
Sosinowski T, Eisenbarth GS
[Reprint] [PubMed]
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Sosinowski T, Eisenbarth GS (2013). Type 1 diabetes: primary antigen/peptide/register/trimolecular complex. Immunol Res, 55 (1-3), 270-6.
Prophylactic use of sublingual allergen immunotherapy in high-risk children: a pilot study
(2013). J Allergy Clin Immunol., 132 (4), 991-3. http://dx.doi.org/10.1016/j.jaci.2013.04.049, PMID: 23768574
Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P
[Reprint] [PubMed]
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Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P (2013). Prophylactic use of sublingual allergen immunotherapy in high-risk children: a pilot study. J Allergy Clin Immunol., 132 (4), 991-3.
HLA-mismatched renal transplantation without maintenance immunosuppression
(2013). N Engl J Med., 368 (19), 1850-2. http://dx.doi.org/10.1056/NEJMc1213779, PMID: 23656665, PMCID: PMC3760499
Kawai T, Sachs DH, Sykes M, Cosimi AB; Immune Tolerance Network
[Reprint] [PubMed]
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Kawai T, Sachs DH, Sykes M, Cosimi AB; Immune Tolerance Network (2013). HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med., 368 (19), 1850-2.
Lymphodepletion and homeostatic proliferation: Implications for transplantation
(2012). Am J Transplant, 12 (5), 1079-1090. http://dx.doi.org/10.1111/j.1600-6143.2012.04008.x, PMID: 22420320
Tchao NK, Turka LA
[Reprint] [PubMed]
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Tchao NK, Turka LA (2012). Lymphodepletion and homeostatic proliferation: Implications for transplantation. Am J Transplant, 12 (5), 1079-1090.
Digital transplantation pathology: combining whole slide imaging, multiplex staining and automated image analysis
(2012). Am J Transplant, 12 (1), 27-37. http://dx.doi.org/10.1111/j.1600-6143.2011.03797.x., PMID: 22053785, PMCID: 3627485
Isse K, Lesniak A, Grama K, Roysam B, Minervini MI, Demetris AJ
[PubMed]
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Isse K, Lesniak A, Grama K, Roysam B, Minervini MI, Demetris AJ (2012). Digital transplantation pathology: combining whole slide imaging, multiplex staining and automated image analysis. Am J Transplant, 12 (1), 27-37.
Humoral autoimmunity in type 1 diabetes: prediction, significance, and detection of distinct disease subtypes
(2012). Cold Spring Harb Perspect Med, 2 (10), na. http://dx.doi.org/10.1101/cshperspect.a012831, PMID: 23028135, PMCID: PMC3475400
Pietropaolo M, Towns R, Eisenbarth GS
[Reprint] [PubMed]
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Pietropaolo M, Towns R, Eisenbarth GS (2012). Humoral autoimmunity in type 1 diabetes: prediction, significance, and detection of distinct disease subtypes. Cold Spring Harb Perspect Med, 2 (10), na.
Prevention of type 1A diabetes mellitus
(2012). Endocr Pract, 18 (5), 745-749. http://dx.doi.org/10.4158/EP12080.OR, PMID: 22548954
Eisenbarth GS
[PubMed]
[Citation View]
Eisenbarth GS (2012). Prevention of type 1A diabetes mellitus. Endocr Pract, 18 (5), 745-749.
Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience
(2012). Rev Diabet Stud, 9 (4), 359-71. http://dx.doi.org/10.1900/RDS.2012.9.359, PMID: 23804273, PMCID: PMC3740703
Ehlers MR, Nepom GT
[Reprint] [PubMed]
[Citation View]
Ehlers MR, Nepom GT (2012). Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience. Rev Diabet Stud, 9 (4), 359-71.
Challenges in the pursuit of immune tolerance
(2011). Immunol Rev, 241 (1), 49-62. http://dx.doi.org/10.1111/j.1600-065X.2011.01003.x, PMID: 21488889, PMCID: 3092524
Nepom GT, St. Clair EW, Turka LA
[Reprint] [PubMed]
[Citation View]
Nepom GT, St. Clair EW, Turka LA (2011). Challenges in the pursuit of immune tolerance. Immunol Rev, 241 (1), 49-62.
Regulatory cells and cell signatures in clinical transplantation tolerance
(2011). Curr Opin Immunol, 23 (5), 655-659. http://dx.doi.org/10.1016/j.coi.2011.07.008, PMID: 21982510
Newell KA, Phippard D, Turka LA
[Reprint] [PubMed]
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Newell KA, Phippard D, Turka LA (2011). Regulatory cells and cell signatures in clinical transplantation tolerance. Curr Opin Immunol, 23 (5), 655-659.
Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism
(2011). Curr Opin Organ Transplant, 16 (4), 366-371. http://dx.doi.org/10.1097/MOT.0b013e3283484b2c, PMID: 21666482, PMCID: 3151013
Kawai T, Cosimi, Sachs DH
[Reprint] [PubMed]
[Citation View]
Kawai T, Cosimi, Sachs DH (2011). Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism. Curr Opin Organ Transplant, 16 (4), 366-371.
Ten years of the Immune Tolerance Network: an integrated clinical research organization
(2010). Sci Transl Med, 2 (19), 1-4. http://dx.doi.org/10.1126/scitranslmed.3000672, PMID: 20371484
Bluestone JA, Krensky AM, Turka LA, Rotrosen D, Matthews JB
[Reprint] [PubMed]
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Bluestone JA, Krensky AM, Turka LA, Rotrosen D, Matthews JB (2010). Ten years of the Immune Tolerance Network: an integrated clinical research organization. Sci Transl Med, 2 (19), 1-4.
Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group
(2010). Clin Exp Immunol, 160 (2), 176-184. , PMID: 20629979, PMCID: 2857940
Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, ITN/JDRF Type 1 Diabetes Combination Therapy Assessment Group
[Reprint] [PubMed]
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Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, ITN/JDRF Type 1 Diabetes Combination Therapy Assessment Group (2010). Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group. Clin Exp Immunol, 160 (2), 176-184.
Bringing transplantation tolerance into the clinic: lessons from the ITN and RISET for the Establishment of Tolerance consortia
(2010). Curr Opin Organ Transplant, 15 (4), 441-448. http://dx.doi.org/10.1097/MOT.0b013e32833bd371, PMID: 20631613
Turka LA, Wood K, Bluestone JA
[PubMed]
[Citation View]
Turka LA, Wood K, Bluestone JA (2010). Bringing transplantation tolerance into the clinic: lessons from the ITN and RISET for the Establishment of Tolerance consortia. Curr Opin Organ Transplant, 15 (4), 441-448.
Immune Tolerance Network at 10 years: Tolerance research at the bedside
(2010). Nat Rev Immunol, 10 (11), 797-803. http://dx.doi.org/10.1038/nri2869, PMID: 20972473
Bluestone JA, Auchincloss H, Nepom GT, Rotrosen D, St. Clair EW, Turka LA
[Reprint] [PubMed]
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Bluestone JA, Auchincloss H, Nepom GT, Rotrosen D, St. Clair EW, Turka LA (2010). Immune Tolerance Network at 10 years: Tolerance research at the bedside. Nat Rev Immunol, 10 (11), 797-803.
Adding value to liver (and allograft) biopsy evaluation using a combination of multiplex quantum dot immunostaining, high-resolution whole-slide digital imaging, and automated image analysis
(2010). Clin Liver Dis, 14 (4), 669-685. http://dx.doi.org/10.1016/j.cld.2010.07.004, PMID: 21055689
Isse K, Grama K, Abbott IM, Lesniak A, Lunz J, Lee WM, Specht S, Corbitt N, Mizuguchi Y, Roysam B, Demetris AJG
[PubMed]
[Citation View]
Isse K, Grama K, Abbott IM, Lesniak A, Lunz J, Lee WM, Specht S, Corbitt N, Mizuguchi Y, Roysam B, Demetris AJG (2010). Adding value to liver (and allograft) biopsy evaluation using a combination of multiplex quantum dot immunostaining, high-resolution whole-slide digital imaging, and automated image analysis. Clin Liver Dis, 14 (4), 669-685.
Marking a path to transplant tolerance
(2008). J Clin Invest, 118 (8), 2684-. http://dx.doi.org/10.1172/JCI36552, PMID: 18654643, PMCID: 2483691
Seyfert-Margolis V, Turka LA
[Reprint] [PubMed]
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Seyfert-Margolis V, Turka LA (2008). Marking a path to transplant tolerance. J Clin Invest, 118 (8), 2684-.
New reagents on the horizon for immune tolerance
(2007). Ann Rev Med, 58 (0), 329–46. , PMID: 16987079
St. Clair EW, Turka LA, Saxon A, Matthews JB, Sayegh MH, Eisenbarth GS, Bluestone J
[Reprint] [PubMed]
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St. Clair EW, Turka LA, Saxon A, Matthews JB, Sayegh MH, Eisenbarth GS, Bluestone J (2007). New reagents on the horizon for immune tolerance. Ann Rev Med, 58 (0), 329–46.
Allorecognition and the alloresponse: clinical implications
(2007). Tissue Antigens, 69 (6), 545-56. , PMID: 17498264
Afzali B, Lechler RI, Hernandez-Fuentes MP
[Reprint] [PubMed]
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Afzali B, Lechler RI, Hernandez-Fuentes MP (2007). Allorecognition and the alloresponse: clinical implications. Tissue Antigens, 69 (6), 545-56.
Role of autoantibodies in type 1 diabetes
(2007). Front Biosci, 12 (0), 1889-1898. , PMID: 17127428
Miao D, Yu L, Eisenbarth GS
[Reprint] [PubMed]
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Miao D, Yu L, Eisenbarth GS (2007). Role of autoantibodies in type 1 diabetes. Front Biosci, 12 (0), 1889-1898.
Interferon alpha--a potential link in the pathogenesis of viral-induced type 1 diabetes and autoimmunity
(2004). Clin Immunol, 111 (3), 225-33. , PMID: 15183143
Devendra D, Eisenbarth GS
[Reprint] [PubMed]
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Devendra D, Eisenbarth GS (2004). Interferon alpha--a potential link in the pathogenesis of viral-induced type 1 diabetes and autoimmunity. Clin Immunol, 111 (3), 225-33.
Type 1 diabetes: recent developments
(2004). BMJ, 328 (7442), 750-754. , PMID: 15044291, PMCID: PMC381328
Devendra D, Liu E, Eisenbarth GS
[Reprint] [PubMed]
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Devendra D, Liu E, Eisenbarth GS (2004). Type 1 diabetes: recent developments. BMJ, 328 (7442), 750-754.
Autoimmune polyendocrine syndromes
(2004). New Engl J Med, 350 (20), 36-47. , PMID: 15141045
Eisenbarth GS, Gottlieb PA
[Reprint] [PubMed]
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Eisenbarth GS, Gottlieb PA (2004). Autoimmune polyendocrine syndromes. New Engl J Med, 350 (20), 36-47.
Disease prevention with islet autoantigens
(2004). Endocrinol Metab Clin North Am, 33 (1), 59-74. , PMID: 15053895
Eisenbarth G, Jasinski J
[Reprint] [PubMed]
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Eisenbarth G, Jasinski J (2004). Disease prevention with islet autoantigens. Endocrinol Metab Clin North Am, 33 (1), 59-74.
What impact will the Immune Tolerance Network have on the future treatment of allergic diseases?
(2004). Clin Exp Allergy, 34 (11), 1657-1659. , PMID: 15544586
Saxon, A
[Reprint] [PubMed]
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Saxon, A (2004). What impact will the Immune Tolerance Network have on the future treatment of allergic diseases?. Clin Exp Allergy, 34 (11), 1657-1659.
Clinical trials of transplant tolerance: slow but steady progress
(2003). Am J Transplant, 3 (7), 794-803. , PMID: 12814471
Matthews JB, Ramos E, Bluestone JA
[Reprint] [PubMed]
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Matthews JB, Ramos E, Bluestone JA (2003). Clinical trials of transplant tolerance: slow but steady progress. Am J Transplant, 3 (7), 794-803.
MHC multimers: expanding the clinical toolkit
(2003). Clin Immunol, 106 (1), 1-4. , PMID: 12584043
Nepom, GT
[Reprint] [PubMed]
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Nepom, GT (2003). MHC multimers: expanding the clinical toolkit. Clin Immunol, 106 (1), 1-4.
The Immune Tolerance Network: a new paradigm for developing tolerance-inducing therapies
(2002). J Allergy Clin Immunol, 110 (1), 17-23. , PMID: 12110811
Rotrosen D, Matthews JB, Bluestone JA
[Reprint] [PubMed]
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Rotrosen D, Matthews JB, Bluestone JA (2002). The Immune Tolerance Network: a new paradigm for developing tolerance-inducing therapies. J Allergy Clin Immunol, 110 (1), 17-23.
The Immune Tolerance Network: tolerance at the crossroads
(2001). Philos Trans R Soc Lond B Biol Sci, 356 (1409), 773-6. , PMID: 11375080, PMCID: PMC1088464
Bluestone JA, Matthews J
[Reprint] [PubMed]
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Bluestone JA, Matthews J (2001). The Immune Tolerance Network: tolerance at the crossroads. Philos Trans R Soc Lond B Biol Sci, 356 (1409), 773-6.
The Immune Tolerance Network and rheumatic disease: immune tolerance comes to the clinic
(2001). Arthritis Rheum, 44 (8), 1730-5. , PMID: 11508422
Diamond B, Bluestone J, Wofsy D
[Reprint] [PubMed]
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Diamond B, Bluestone J, Wofsy D (2001). The Immune Tolerance Network and rheumatic disease: immune tolerance comes to the clinic. Arthritis Rheum, 44 (8), 1730-5.
The Immune Tolerance Network--an NIH/JDF-supported initiative to bring tolerance research into the clinic: a major new resource for clinical immunologists
(2000). Clin Immunol, 96 (3), 171-3. , PMID: 10964534
Bluestone JA, Matthews JB
[Reprint] [PubMed]
[Citation View]
Bluestone JA, Matthews JB (2000). The Immune Tolerance Network--an NIH/JDF-supported initiative to bring tolerance research into the clinic: a major new resource for clinical immunologists. Clin Immunol, 96 (3), 171-3.