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Blood Transcriptomics & Repertoire Core

Principal Investigator

Eoin McKinney | University of Cambridge | Cambridge, UK
Peter Linsley | Benaroya Research Institute | Seattle, WA

Abstract

The ITN engages two labs for RNAseq analysis of ITN trial blood samples:

  • Peter Linsley's group specializes in RNAseq on T1D studies. They also perform TCR repertoire studies on sorted cell populations and on single-cell, tetramer-positive, antigen-specific cells, using the Adaptive Biotechnologies analytic platform.
  • Eoin McKinney's group provides a combination of whole blood transcriptomics, sorted lymphocyte population transcriptomics, and validation through functional studies. 

Principal Investigator

Eoin McKinney | University of Cambridge | Cambridge, UK
Peter Linsley | Benaroya Research Institute | Seattle, WA

The Immune Tolerance Network and is sponsored by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

National Institute of Allergy and Infectious Diseases

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