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May 14, 2012

New Review: Lymphodepletion and homeostatic proliferation in transplantation

In a recently published review in the American Journal of Transplantation, ITN authors Nadia Tchao, MD and Laurence Turka, MD discuss the biology of lymphocyte depletion and considerations for strategies that aim to promote pro-tolerogenic reconstitution in transplant settings. The depletion of lymphocytes (T cells and B cells) is a strategy increasingly being used to help prevent rejection in transplant settings by reducing the pool of alloreactive cells.
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May 9, 2012

T1DAL Study Completes Enrollment

The T1DAL ITN045AI clinical research study for recently diagnosed type 1 diabetes has completed enrollment at 19 clinical centers across the U.S. T1DAL is a randomized, placebo-controlled research study for participants between the ages of 12-35 and recently diagnosed with type 1 diabetes. The goal of this trial is to determine whether the drug alefacept (Amevive ®) can delay or permanently halt the destruction of beta cells in new-onset type 1 diabetes.
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May 1, 2012

NIH Renews Its Dedication to Fighting Worldwide Asthma

This World Asthma Day 2012, NIH renews its commitment to working with individuals, families, and healthcare professionals to reduce the worldwide burden of asthma. We commend the NIH-supported investigators who continue to make significant progress in asthma research, and we express our gratitude to the people who have participated in NIH-sponsored asthma research studies, as well as to the organizations that provide support for those affected by this disease.Read the NIH joint statement on World Asthma Day.
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